1KT6
 
 | | Crystal structure of bovine holo-RBP at pH 9.0 | | Descriptor: | RETINOL, plasma retinol-binding protein | | Authors: | Calderone, V, Berni, R, Zanotti, G. | | Deposit date: | 2002-01-15 | | Release date: | 2003-06-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | High-resolution Structures of Retinol-binding Protein in
Complex with Retinol: pH-induced Protein Structural
Changes in the Crystal State
J.Mol.Biol., 329, 2003
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1KT4
 | | Crystal structure of bovine holo-RBP at pH 3.0 | | Descriptor: | RETINOL, plasma retinol-binding protein | | Authors: | Calderone, V, Berni, R, Zanotti, G. | | Deposit date: | 2002-01-15 | | Release date: | 2003-06-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.461 Å) | | Cite: | High-resolution Structures of Retinol-binding Protein in
Complex with Retinol: pH-induced Protein Structural
Changes in the Crystal State
J.Mol.Biol., 329, 2003
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1RBP
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2AD9
 | | Solution structure of Polypyrimidine Tract Binding protein RBD1 complexed with CUCUCU RNA | | Descriptor: | 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 | | Authors: | Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. | | Deposit date: | 2005-07-20 | | Release date: | 2005-10-04 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
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1KT5
 | | Crystal structure of bovine holo-RBP at pH 4.0 | | Descriptor: | Plasma retinol-binding protein, RETINOL | | Authors: | Calderone, V, Berni, R, Zanotti, G. | | Deposit date: | 2002-01-15 | | Release date: | 2003-06-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | High-resolution Structures of Retinol-binding Protein in
Complex with Retinol: pH-induced Protein Structural
Changes in the Crystal State
J.Mol.Biol., 329, 2003
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6RX5
 | | Trypanosoma brucei PTR1 (TbPTR1) in complex with inhibitor 1 (NMT-C0003) | | Descriptor: | ACETATE ION, GLYCEROL, METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE, ... | | Authors: | Landi, G, Pozzi, C, Mangani, S. | | Deposit date: | 2019-06-07 | | Release date: | 2020-07-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
J.Med.Chem., 65, 2022
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1JYD
 | | Crystal Structure of Recombinant Human Serum Retinol-Binding Protein at 1.7 A Resolution | | Descriptor: | GLYCEROL, PLASMA RETINOL-BINDING PROTEIN | | Authors: | Greene, L.H, Chrysina, E.D, Irons, L.I, Papageorgiou, A.C, Acharya, K.R, Brew, K. | | Deposit date: | 2001-09-12 | | Release date: | 2003-07-01 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Role of conserved residues in structure and stability: Tryptophans of human serum
retinol-binding protein, a model for the lipocalin superfamily
Protein Sci., 10, 2001
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2ADC
 | | Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA | | Descriptor: | 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 | | Authors: | Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. | | Deposit date: | 2005-07-20 | | Release date: | 2005-10-04 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
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2ADB
 | | Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA | | Descriptor: | 5'-R(*CP*UP*CP*UP*CP*U)-3', Polypyrimidine tract-binding protein 1 | | Authors: | Oberstrass, F.C, Auweter, S.D, Erat, M, Hargous, Y, Henning, A, Wenter, P, Reymond, L, Pitsch, S, Black, D.L, Allain, F.H.T. | | Deposit date: | 2005-07-20 | | Release date: | 2005-10-04 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of PTB bound to RNA: specific binding and implications for splicing regulation
Science, 309, 2005
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1FEL
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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2EVZ
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1HBQ
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1FEN
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | ALL-TRANS AXEROPHTHENE, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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1HBP
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3BSZ
 | | Crystal structure of the transthyretin-retinol binding protein-Fab complex | | Descriptor: | Fab fragment heavy chain, Fab fragment light chain, Plasma retinol-binding protein, ... | | Authors: | Zanotti, G, Cendron, L, Gliubich, F, Folli, C, Berni, R. | | Deposit date: | 2007-12-27 | | Release date: | 2008-11-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.38 Å) | | Cite: | Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein.
Febs J., 275, 2008
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1FEM
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | RETINOIC ACID, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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1IIU
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7OPJ
 | | Trypanosoma brucei PTR1 (TbPTR1) in complex with pyrimethamine | | Descriptor: | 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, ACETATE ION, GLYCEROL, ... | | Authors: | Tassone, G, Landi, G, Pozzi, C, Mangani, S. | | Deposit date: | 2021-05-31 | | Release date: | 2021-07-14 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase.
Pharmaceuticals, 14, 2021
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3ZZY
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3ZZZ
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4DX9
 | | ICAP1 in complex with integrin beta 1 cytoplasmic tail | | Descriptor: | Integrin beta-1, Integrin beta-1-binding protein 1 | | Authors: | Liu, W, Draheim, K, Zhang, R, Calderwood, D.A, Boggon, T.J. | | Deposit date: | 2012-02-27 | | Release date: | 2013-01-09 | | Last modified: | 2020-09-02 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation.
Mol.Cell, 49, 2013
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6RX0
 | | Trypanosoma brucei PTR1 (TbPTR1) in complex with inhibitor 3 (NMT-C0013) | | Descriptor: | ACETATE ION, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Landi, G, Pozzi, C, Mangani, S. | | Deposit date: | 2019-06-07 | | Release date: | 2020-07-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
J.Med.Chem., 65, 2022
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5HSQ
 | | The surface engineered photosensory module (PAS-GAF-PHY) of the bacterial phytochrome Agp1 (AtBphP1) in the Pr form, chromophore modelled with an endocyclic double bond in pyrrole ring A. | | Descriptor: | BILIVERDINE IX ALPHA, Bacteriophytochrome protein, CALCIUM ION, ... | | Authors: | Nagano, S, Scheerer, P, Zubow, K, Lamparter, T, Krauss, N. | | Deposit date: | 2016-01-26 | | Release date: | 2016-08-03 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Crystal Structures of the N-terminal Photosensory Core Module of Agrobacterium Phytochrome Agp1 as Parallel and Anti-parallel Dimers.
J.Biol.Chem., 291, 2016
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6GD4
 | | Trypanosoma brucei PTR1 in complex with inhibitor 4c (F188) | | Descriptor: | 2-amino-1,3-benzothiazole-6-carboxamide, ACETATE ION, GLYCEROL, ... | | Authors: | Landi, G, Pozzi, C, Mangani, S. | | Deposit date: | 2018-04-21 | | Release date: | 2019-04-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.
J.Med.Chem., 62, 2019
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6GCQ
 | | Trypanosoma brucei PTR1 in complex with inhibitor 2b (F192) | | Descriptor: | 6-(trifluoromethylsulfanyl)-1,3-benzothiazol-2-amine, ACETATE ION, DIMETHYL SULFOXIDE, ... | | Authors: | Pozzi, C, Landi, G, Mangani, S. | | Deposit date: | 2018-04-18 | | Release date: | 2019-04-03 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections.
J.Med.Chem., 62, 2019
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