1KGA
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2X52
| CRYSTAL STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 3 IN COMPLEX WITH A SYNTHETIC DIVALENT CARBOHYDRATE LIGAND | Descriptor: | AGGLUTININ ISOLECTIN 3, BIS-(2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSYLOXYCARBONYL)-4,7,10-TRIOXA-1,13-TRIDECANEDIAMINE, GLYCEROL | Authors: | Schwefel, D, Maierhofer, C, Wittmann, V, Diederichs, K, Welte, W. | Deposit date: | 2010-02-05 | Release date: | 2010-02-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Multivalent Binding to Wheat Germ Agglutinin. J.Am.Chem.Soc., 132, 2010
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6BIT
| SIRPalpha antibody complex | Descriptor: | KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1 | Authors: | Ring, N.G, Herndler-Brandstetter, D, Weiskopf, K, Shan, L, Volkmer, J.P, George, B.M, Lietzenmayer, M, McKenna, K.M, Naik, T.J, McCarty, A, Zheng, Y, Ring, A.M, Flavell, R.A, Weissman, I.L. | Deposit date: | 2017-11-03 | Release date: | 2017-12-06 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2.191 Å) | Cite: | Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5D3W
| Crystal Structure of the P-Rex1 PH domain with Sulfate Bound | Descriptor: | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, SULFATE ION | Authors: | Cash, J.N, Tesmer, J.J.G. | Deposit date: | 2015-08-06 | Release date: | 2016-04-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.852 Å) | Cite: | Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. Structure, 24, 2016
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5DDF
| Menin in complex with MI-273 | Descriptor: | 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-(pentafluoroethyl)thieno[2,3-d]pyrimidine, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | Authors: | Pollock, J, Dmitry, B, Cierpicki, T, Grembecka, J. | Deposit date: | 2015-08-24 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand Complexes. J.Med.Chem., 58, 2015
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4WFX
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4JPX
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4JQ9
| Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex | Descriptor: | CHLORIDE ION, Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Tietzel, M, Neumann, P, Meyer, D, Ficner, R, Tittmann, K. | Deposit date: | 2013-03-20 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Dihydrolipoyl dehydrogenase of Escherichia coli pyruvate dehydrogenase complex TO BE PUBLISHED
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6WXG
| Cryo-EM reconstruction of VP5*/VP8* assembly from rhesus rotavirus particles - Reversed conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Intermediate capsid protein VP6, ... | Authors: | Herrmann, T, Harrison, S.C, Jenni, S. | Deposit date: | 2020-05-10 | Release date: | 2021-01-20 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Functional refolding of the penetration protein on a non-enveloped virus. Nature, 590, 2021
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5DEN
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4JSJ
| Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((5-(((3-fluorophenethyl)amino)methyl)pyridin-3-yl)oxy)methyl)-4-methylpyridin-2-amine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-({[5-({[2-(3-fluorophenyl)ethyl]amino}methyl)pyridin-3-yl]oxy}methyl)-4-methylpyridin-2-amine, ACETATE ION, ... | Authors: | Li, H, Poulos, T.L. | Deposit date: | 2013-03-22 | Release date: | 2013-08-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | In search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structures. Bioorg.Med.Chem., 21, 2013
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3G5H
| Crystallographic analysis of cytochrome P450 cyp121 | Descriptor: | (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Belin, P, Le Du, M.H, Gondry, M. | Deposit date: | 2009-02-05 | Release date: | 2009-04-21 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.USA, 106, 2009
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1KRN
| STRUCTURE OF KRINGLE 4 AT 4C TEMPERATURE AND 1.67 ANGSTROMS RESOLUTION | Descriptor: | PLASMINOGEN, SULFATE ION | Authors: | Stec, B, Teeter, M.M, Whitlow, M, Yamano, A. | Deposit date: | 1995-06-21 | Release date: | 1997-01-11 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structure of human plasminogen kringle 4 at 1.68 a and 277 K. A possible structural role of disordered residues. Acta Crystallogr.,Sect.D, 53, 1997
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4JMW
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2C0M
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2BF2
| Crystal structure of native toluene-4-monooxygenase catalytic effector protein, T4moD | Descriptor: | TOLUENE-4-MONOOXYGENASE SYSTEM PROTEIN D | Authors: | Lountos, G.T, Mitchell, K.H, Studts, J.M, Fox, B.G, Orville, A.M. | Deposit date: | 2004-12-03 | Release date: | 2005-05-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures and Functional Studies of T4Mod, the Toluene 4-Monooxygenase Catalytic Effector Protein Biochemistry, 44, 2005
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4JNC
| Soluble Epoxide Hydrolase complexed with a carboxamide inhibitor | Descriptor: | 1-[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]-N-[2-(trifluoromethyl)benzyl]piperidine-4-carboxamide, Bifunctional epoxide hydrolase 2 | Authors: | Shewchuk, L.M. | Deposit date: | 2013-03-15 | Release date: | 2013-06-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase. Bioorg.Med.Chem.Lett., 23, 2013
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4WRF
| Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) Complexed with Mannose | Descriptor: | CALCIUM ION, CHLORIDE ION, HEXANE-1,6-DIOL, ... | Authors: | Rynkiewicz, M.J, Wu, H, Cafarella, T.R, Nikolaidis, N.M, Head, J.F, Seaton, B.A, McCormack, F.X. | Deposit date: | 2014-10-23 | Release date: | 2016-02-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop To be published
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2BWP
| 5-Aminolevulinate Synthase from Rhodobacter capsulatus in complex with glycine | Descriptor: | 5-AMINOLEVULINATE SYNTHASE, ACETIC ACID, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE] | Authors: | Astner, I, Schulze, J.O, Van Den Heuvel, J.J, Jahn, D, Schubert, W.-D, Heinz, D.W. | Deposit date: | 2005-07-15 | Release date: | 2005-09-27 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and its Link to Xlsa in Humans. Embo J., 24, 2005
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1KIV
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6CAM
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1KDU
| SEQUENTIAL 1H NMR ASSIGNMENTS AND SECONDARY STRUCTURE OF THE KRINGLE DOMAIN FROM UROKINASE | Descriptor: | PLASMINOGEN ACTIVATOR | Authors: | Li, X, Bokman, A.M, Llinas, M, Smith, R.A.G, Dobson, C.M. | Deposit date: | 1993-07-15 | Release date: | 1993-10-31 | Last modified: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | Solution structure of the kringle domain from urokinase-type plasminogen activator. J.Mol.Biol., 235, 1994
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2XKR
| Crystal Structure of Mycobacterium tuberculosis CYP142: A novel cholesterol oxidase | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 142, TETRAETHYLENE GLYCOL | Authors: | Driscoll, M, McLean, K.J, Levy, C.W, Lafite, P, Mast, N, Pikuleva, I.A, Rigby, S.E.J, Leys, D, Munro, A.W. | Deposit date: | 2010-07-12 | Release date: | 2010-09-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Structural and Biochemical Characterization of Mycobacterium Tuberculosis Cyp142: Evidence for Multiple Cholesterol 27-Hydroxylase Activities in a Human Pathogen. J.Biol.Chem., 285, 2010
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2BNH
| PORCINE RIBONUCLEASE INHIBITOR | Descriptor: | RIBONUCLEASE INHIBITOR | Authors: | Kobe, B, Deisenhofer, J. | Deposit date: | 1996-06-29 | Release date: | 1997-03-12 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A. J.Mol.Biol., 264, 1996
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6BGV
| LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR 2-((2-chlorophenyl)(2-(piperidin-1-yl)ethoxy)methyl)-1l2-pyrrolo[3,2-b]pyridine-7-carboxylic acid (Compound N40) | Descriptor: | 1,2-ETHANEDIOL, 2-{(S)-(2-chlorophenyl)[2-(piperidin-1-yl)ethoxy]methyl}-1H-pyrrolo[3,2-b]pyridine-7-carboxylic acid, DIMETHYL SULFOXIDE, ... | Authors: | Horton, J.R, Cheng, X. | Deposit date: | 2017-10-29 | Release date: | 2018-03-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.592 Å) | Cite: | Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A. J. Med. Chem., 61, 2018
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