6WUE
 
 | | Tetragonal crystal form of SbtB from Synechocystis PCC6803 | | Descriptor: | ISOPROPYL ALCOHOL, Membrane-associated protein slr1513, SODIUM ION | | Authors: | Bu, G, Simmons, C.R, Nielsen, D.R, Nannenga, B.L. | | Deposit date: | 2020-05-04 | | Release date: | 2020-08-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Tetragonal crystal form of the cyanobacterial bicarbonate-transporter regulator SbtB from Synechocystis sp. PCC 6803.
Acta Crystallogr.,Sect.F, 76, 2020
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5O3Q
 | | Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803 in complex with cyclic AMP (cAMP) | | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, BICARBONATE ION, Membrane-associated protein slr1513 | | Authors: | Selim, K.A, Albrecht, R, Forchhammer, K, Hartmann, M.D. | | Deposit date: | 2017-05-24 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | PII-like signaling protein SbtB links cAMP sensing with cyanobacterial inorganic carbon response.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5L9N
 | | Structure of uridylylated GlnB from Escherichia coli bound to ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nitrogen regulatory protein P-II 1 | | Authors: | Rubio, V, Palanca, C. | | Deposit date: | 2016-06-10 | | Release date: | 2017-04-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.901 Å) | | Cite: | Effects of T-loop modification on the PII-signalling protein: structure of uridylylated Escherichia coli GlnB bound to ATP.
Environ Microbiol Rep, 9, 2017
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3L7P
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3DFE
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3LF0
 | | Crystal structure of the ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Nitrogen regulatory protein P-II | | Authors: | Shetty, N.D, Palaninathan, S.K, Reddy, M.C.M, Owen, J.L, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2010-01-15 | | Release date: | 2010-07-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein.
Protein Sci., 19, 2010
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6N4A
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1PIL
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3MHY
 | | A New PII Protein Structure | | Descriptor: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-OXOGLUTARIC ACID, ... | | Authors: | Winkler, F.K, Truan, D, Li, X.D. | | Deposit date: | 2010-04-09 | | Release date: | 2010-06-09 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A new P(II) protein structure identifies the 2-oxoglutarate binding site.
J.Mol.Biol., 400, 2010
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6YC6
 | | Structure of C. glutamicum GlnK | | Descriptor: | 1,2-ETHANEDIOL, PHOSPHATE ION, PII protein | | Authors: | Grau, F.C, Muller, Y.A. | | Deposit date: | 2020-03-18 | | Release date: | 2021-03-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of adenylylated and unadenylylated P II protein GlnK from Corynebacterium glutamicum.
Acta Crystallogr D Struct Biol, 77, 2021
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6YC7
 | | Structure of adenylylated C. glutamicum GlnK | | Descriptor: | ADENINE ARABINOSE-5'-PHOSPHATE, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Grau, F.C, Muller, Y.A. | | Deposit date: | 2020-03-18 | | Release date: | 2021-03-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structures of adenylylated and unadenylylated P II protein GlnK from Corynebacterium glutamicum.
Acta Crystallogr D Struct Biol, 77, 2021
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6NTB
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2Z0G
 | | The crystal structure of PII protein | | Descriptor: | CHLORIDE ION, Nitrogen regulatory protein P-II, PHOSPHATE ION | | Authors: | Sakai, H, Shinkai, A, Kitamura, Y, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-05-07 | | Release date: | 2008-05-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The crystal structure of PII protein
To be Published
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4R25
 | | Structure of B. subtilis GlnK | | Descriptor: | Nitrogen regulatory PII-like protein, ZINC ION | | Authors: | Schumacher, M.A. | | Deposit date: | 2014-08-08 | | Release date: | 2015-03-04 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5193 Å) | | Cite: | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
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4RX6
 | | Structure of B. subtilis GlnK-ATP complex to 2.6 Angstrom | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Nitrogen regulatory PII-like protein | | Authors: | Schumacher, M.A, Cuthbert, B, Tonthat, N, Chinnam, N.G, Whitfill, T. | | Deposit date: | 2014-12-09 | | Release date: | 2015-12-30 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5994 Å) | | Cite: | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
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4AFF
 | | High resolution structure of a PII mutant (I86N) protein in complex with ATP, MG and FLC | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CITRATE ANION, MAGNESIUM ION, ... | | Authors: | Zeth, K, Fokina, O, Chellamuthu, V.R, Forchhammer, K. | | Deposit date: | 2012-01-19 | | Release date: | 2012-02-01 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | An Engineered Pii Protein Variant that Senses a Novel Ligand: Atomic Resolution Structure of the Complex with Citrate.
Acta Crystallogr.,Sect.D, 68, 2012
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1GNK
 | | GLNK, A SIGNAL PROTEIN FROM E. COLI | | Descriptor: | PROTEIN (GLNK), SULFATE ION | | Authors: | Xu, Y, Cheah, E, Carr, P.D, Vanheeswijk, W.C, Westerhoff, H.V, Vasudevan, S.G, Ollis, D.L. | | Deposit date: | 1998-07-14 | | Release date: | 1999-07-23 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | GlnK, a PII-homologue: structure reveals ATP binding site and indicates how the T-loops may be involved in molecular recognition.
J.Mol.Biol., 282, 1998
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3BZQ
 | | High resolution crystal structure of Nitrogen Regulatory Protein (Rv2919c) of Mycobacterium tuberculosis | | Descriptor: | Nitrogen regulatory protein P-II | | Authors: | Reddy, M.C, Palaninathan, S.K, Shetty, N.D, Owen, J.L, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2008-01-18 | | Release date: | 2008-04-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structures of the apo and ATP bound Mycobacterium tuberculosis nitrogen regulatory PII protein.
Protein Sci., 19, 2010
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1HWU
 | | STRUCTURE OF PII PROTEIN FROM HERBASPIRILLUM SEROPEDICAE | | Descriptor: | PII PROTEIN | | Authors: | Benelli, E.M, Buck, M, Polikarpov, I, De Souza, E.M, Cruz, L.M, Pedrosa, F.O. | | Deposit date: | 2001-01-10 | | Release date: | 2003-06-17 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK.
Eur.J.Biochem., 269, 2002
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1QY7
 | | The structure of the PII protein from the cyanobacteria Synechococcus sp. PCC 7942 | | Descriptor: | NICKEL (II) ION, Nitrogen regulatory protein P-II, SULFATE ION | | Authors: | Xu, Y, Carr, P.D, Clancy, P, Garcia-Dominguez, M, Forchhammer, K, Florencio, F, Tandeau de Marsac, N, Vasudevan, S.G, Ollis, D.L. | | Deposit date: | 2003-09-09 | | Release date: | 2003-09-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structures of the PII proteins from the cyanobacteria Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803.
Acta Crystallogr.,Sect.D, 59, 2003
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4C3L
 | | Structure of wildtype PII from S. elongatus at high resolution | | Descriptor: | CHLORIDE ION, NITROGEN REGULATORY PROTEIN P-II, TETRAETHYLENE GLYCOL | | Authors: | Zeth, K, Forchhammer, K. | | Deposit date: | 2013-08-25 | | Release date: | 2014-01-15 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural Basis and Target-Specific Modulation of Adp Sensing by the Synechococcus Elongatus Pii Signaling Protein.
J.Biol.Chem., 289, 2014
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7OBJ
 | | Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803 in complex with cyclic di-AMP (c-di-AMP) | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Membrane-associated protein slr1513 | | Authors: | Selim, K.A, Albrecht, R, Hartmann, M.D. | | Deposit date: | 2021-04-22 | | Release date: | 2022-02-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Diurnal metabolic control in cyanobacteria requires perception of second messenger signaling molecule c-di-AMP by the carbon control protein SbtB.
Sci Adv, 7, 2021
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7O4X
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7P52
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5O3R
 | | Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803 in complex with AMP | | Descriptor: | ADENOSINE MONOPHOSPHATE, BICARBONATE ION, Membrane-associated protein slr1513 | | Authors: | Selim, K.A, Forchhammer, K, Albrecht, R, Hartmann, M.D. | | Deposit date: | 2017-05-24 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | PII-like signaling protein SbtB links cAMP sensing with cyanobacterial inorganic carbon response.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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