PDB: 52 件ウェブページステータス検索Chemie searchBIRD

---

2CBL	N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE ON ZAP-70 分子名称: CALCIUM ION, PROTO-ONCOGENE CBL, ZAP-70 著者 Meng, W, Sawasdikosol, S, Burakoff, S.J, Eck, M.J. 登録日 1998-08-28 公開日 1999-05-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature, 398, 1999
1B47	STRUCTURE OF THE N-TERMINAL DOMAIN OF CBL IN COMPLEX WITH ITS BINDING SITE IN ZAP-70 分子名称: CALCIUM ION, CBL 著者 Meng, W, Sawasdikosol, S, Burakoff, S.J, Eck, M.J. 登録日 1999-01-06 公開日 1999-04-27 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase. Nature, 398, 1999
1FBV	STRUCTURE OF A CBL-UBCH7 COMPLEX: RING DOMAIN FUNCTION IN UBIQUITIN-PROTEIN LIGASES 分子名称: SIGNAL TRANSDUCTION PROTEIN CBL, SULFATE ION, UBIQUITIN-CONJUGATING ENZYME E12-18 KDA UBCH7, ... 著者 Zheng, N, Wang, P, Jeffrey, P.D, Pavletich, N.P. 登録日 2000-07-17 公開日 2000-08-30 最終更新日 2017-10-04 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell(Cambridge,Mass.), 102, 2000
1YVH	Crystal Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide 分子名称: 13-mer fragment of SH2 and PH domain-containing adapter protein APS, CBL E3 ubiquitin protein ligase, MAGNESIUM ION 著者 Hu, J, Hubbard, S.R. 登録日 2005-02-15 公開日 2005-03-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins J.Biol.Chem., 280, 2005
3BUX	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in c-Met 分子名称: 13-meric peptide from Hepatocyte growth factor receptor, E3 ubiquitin-protein ligase CBL 著者 Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. 登録日 2008-01-03 公開日 2008-02-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
3BUM	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2 分子名称: E3 ubiquitin-protein ligase CBL, Protein sprouty homolog 2 著者 Ng, C, Jackson, A.R, Buschdorf, P.J, Sun, Q, Guy, R.G, Sivaraman, J. 登録日 2008-01-03 公開日 2008-02-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
3BUW	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Syk 分子名称: 13-meric peptide from Tyrosine-protein kinase SYK, E3 ubiquitin-protein ligase CBL 著者 Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. 登録日 2008-01-03 公開日 2008-02-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
3BUO	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in EGF receptor' 分子名称: 13-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL 著者 Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. 登録日 2008-01-03 公開日 2008-02-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
3BUN	Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty4 分子名称: 13-meric peptide from Protein sprouty homolog 4, E3 ubiquitin-protein ligase CBL 著者 Ng, C, Jackson, R.A, Buschdorf, J.P, Sun, Q, Guy, G.R, Sivaraman, J. 登録日 2008-01-03 公開日 2008-02-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for a novel intrapeptidyl H-bond and reverse binding of c-Cbl-TKB domain substrates Embo J., 27, 2008
3OB1	Crystal structure of c-Cbl TKB domain in complex with double phosphorylated Spry2 peptide 分子名称: 12-meric peptide from Protein sprouty homolog 2, E3 ubiquitin-protein ligase CBL 著者 Sun, Q, Sivaraman, J. 登録日 2010-08-06 公開日 2010-08-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain Plos One, 5, 2010
3OB2	Crystal structure of c-Cbl TKB domain in complex with double phosphorylated EGFR peptide 分子名称: 12-meric peptide from Epidermal growth factor receptor, E3 ubiquitin-protein ligase CBL 著者 Sun, Q, Sivaraman, J. 登録日 2010-08-06 公開日 2010-08-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Additional serine/threonine phosphorylation reduces binding affinity but preserves interface topography of substrate proteins to the c-Cbl TKB domain Plos One, 5, 2010
3OP0	Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide 分子名称: Epidermal growth factor receptor, NICKEL (II) ION, SODIUM ION, ... 著者 Chaikuad, A, Guo, K, Cooper, C.D.O, Ayinampudi, V, Krojer, T, Ugochukwu, E, Muniz, J.R.C, Vollmar, M, Canning, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2010-08-31 公開日 2010-10-20 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Crystal structure of Cbl-c (Cbl-3) TKB domain in complex with EGFR pY1069 peptide To be Published
3PFV	Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide 分子名称: 1,2-ETHANEDIOL, 11-meric peptide from Epidermal growth factor receptor, CHLORIDE ION, ... 著者 Chaikuad, A, Guo, K, Cooper, C.D.O, Ayinampudi, V, Krojer, T, Muniz, J.R.C, Vollmar, M, Canning, P, Gileadi, O, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) 登録日 2010-10-29 公開日 2010-12-08 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide To be Published
3PLF	Reverse Binding Mode of MetRD peptide complexed with c-Cbl TKB domain 分子名称: CALCIUM ION, CHLORIDE ION, E3 ubiquitin-protein ligase CBL, ... 著者 Sun, Q, Sivaraman, J. 登録日 2010-11-15 公開日 2010-12-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding Febs Lett., 585, 2011
2Y1N	Structure of c-Cbl-ZAP-70 peptide complex 分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, TYROSINE-PROTEIN KINASE ZAP-70 ZAP-70,70 KDA ZETA-ASSOCIATED PROTEIN, ... 著者 Dou, H, Sibbet, G.J, Huang, D.T. 登録日 2010-12-08 公開日 2012-01-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl. Nat.Struct.Mol.Biol., 19, 2012
2Y1M	Structure of native c-Cbl 分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, ZINC ION 著者 Dou, H, Sibbet, G.J, Huang, D.T. 登録日 2010-12-08 公開日 2012-01-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl. Nat.Struct.Mol.Biol., 19, 2012
3VGO	Crystal structure of the N-terminal fragment of Cbl-b 分子名称: E3 ubiquitin-protein ligase CBL-B 著者 Kobashigawa, Y, Noda, N.N, Inagaki, F. 登録日 2011-08-18 公開日 2011-12-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b Proc.Natl.Acad.Sci.USA, 108, 2011
4A4C	Structure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex 分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ... 著者 Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T. 登録日 2011-10-08 公開日 2012-01-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.704 Å) 主引用文献 Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl Nat.Struct.Mol.Biol., 19, 2012
4A4B	Structure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex 分子名称: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ... 著者 Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T. 登録日 2011-10-08 公開日 2012-01-25 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.789 Å) 主引用文献 Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl Nat.Struct.Mol.Biol., 19, 2012
3VRN	Crystal structure of the tyrosine kinase binding domain of Cbl-c 分子名称: CALCIUM ION, Signal transduction protein CBL-C 著者 Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. 登録日 2012-04-13 公開日 2013-03-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c J.Biochem., 152, 2012
3VRQ	Crystal structure of the tyrosine kinase binding domain of Cbl-c (PL mutant) 分子名称: CALCIUM ION, Signal transduction protein CBL-C 著者 Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. 登録日 2012-04-13 公開日 2013-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c. J.Biochem., 152, 2012
3VRR	Crystal structure of the tyrosine kinase binding domain of Cbl-c (PL mutant) in complex with phospho-EGFR peptide 分子名称: CALCIUM ION, Epidermal growth factor receptor, Signal transduction protein CBL-C 著者 Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. 登録日 2012-04-13 公開日 2013-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c. J.Biochem., 152, 2012
3VRP	Crystal structure of the tyrosine kinase binding domain of Cbl-c in complex with phospho-EGFR peptide 分子名称: CALCIUM ION, Epidermal growth factor receptor, Signal transduction protein CBL-C 著者 Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. 登録日 2012-04-13 公開日 2013-03-06 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c. J.Biochem., 152, 2012
3VRO	Crystal structure of the tyrosine kinase binding domain of Cbl-c in complex with phospho-Src peptide 分子名称: CALCIUM ION, Proto-oncogene tyrosine-protein kinase Src, Signal transduction protein CBL-C 著者 Takeshita, K, Tezuka, T, Isozaki, Y, Yamashita, E, Suzuki, M, Yamanashi, Y, Yamamoto, T, Nakagawa, A. 登録日 2012-04-13 公開日 2013-03-06 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c. J.Biochem., 152, 2012
4GPL	Structure of Cbl(TKB) bound to a phosphorylated pentapeptide 分子名称: ACE-PTR-THR-PRO-GLU-PRO, PEPTIDE INHIBITOR, E3 ubiquitin-protein ligase CBL 著者 Borgstahl, G, Natarajan, A. 登録日 2012-08-21 公開日 2013-09-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The paradox of conformational constraint in the design of Cbl(TKB)-binding peptides. Sci Rep, 3, 2013

 

123>