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8F8Z
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PHF2 (PHD+JMJ) in Complex with H3 Histone N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, H3 N-Terminal Peptide, Lysine-specific demethylase PHF2, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
8F8Y
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PHF2 (PHD+JMJ) in Complex with VRK1 N-Terminal Peptide
分子名称: 1,2-ETHANEDIOL, Lysine-specific demethylase PHF2, SULFATE ION, ...
著者Horton, J.R, Cheng, X.
登録日2022-11-22
公開日2023-01-18
最終更新日2023-02-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2.
J.Biol.Chem., 299, 2022
7YTA
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crystal structure of NtAGDP3 AGD1-2 in complex with an H3K9me2 peptide
分子名称: AGDP3 AGD1-2, H3(1-15)K9me2 peptide
著者Zhou, X, Du, J.
登録日2022-08-13
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The H3K9me2-binding protein AGDP3 limits DNA methylation and transcriptional gene silencing in Arabidopsis.
J Integr Plant Biol, 64, 2022
7YT9
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crystal structure of AGD1-4 of Arabidopsis AGDP3
分子名称: AGD1-4 of Arabidopsis AGDP3
著者Zhou, X, Du, J.
登録日2022-08-13
公開日2022-10-12
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The H3K9me2-binding protein AGDP3 limits DNA methylation and transcriptional gene silencing in Arabidopsis.
J Integr Plant Biol, 64, 2022
7XUD
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Structure of G9a in complex with compound 26a
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T.
登録日2022-05-18
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
7XUC
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Structure of G9a in complex with compound 11a
分子名称: 1,2-ETHANEDIOL, 3,6,6-trimethyl-4-oxidanylidene-~{N}-[(2~{S})-1-oxidanylidene-1-phenylazanyl-hexan-2-yl]-5,7-dihydro-1~{H}-indole-2-carboxamide, CHLORIDE ION, ...
著者Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T.
登録日2022-05-18
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
7XUB
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Structure of G9a in complex with compound 10d
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ...
著者Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T.
登録日2022-05-18
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
7XUA
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Structure of G9a in complex with compound 10a
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ...
著者Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T.
登録日2022-05-18
公開日2023-03-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents.
J.Med.Chem., 66, 2023
7XPK
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crystal structure of rice ASI1 BAH domain in complex with a rice SUVH6 peptide
分子名称: Alpha-aminoacylpeptide hydrolase, BAH domain-containing protein
著者Yuan, J, Du, J.
登録日2022-05-04
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis of locus-specific H3K9 methylation catalyzed by SUVH6 in plants.
Proc.Natl.Acad.Sci.USA, 120, 2023
7XPJ
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crystal structure of rice ASI1 BAH domain
分子名称: BAH domain-containing protein
著者Yuan, J, Du, J.
登録日2022-05-04
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Molecular basis of locus-specific H3K9 methylation catalyzed by SUVH6 in plants.
Proc.Natl.Acad.Sci.USA, 120, 2023
7VZ2
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Crystal structure of chromodomain of Arabidopsis LHP1
分子名称: Chromo domain-containing protein LHP1, UNKNOWN ATOM OR ION
著者Liu, Y, Min, J.
登録日2021-11-15
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for the recognition of methylated histone H3 by the Arabidopsis LHP1 chromodomain.
J.Biol.Chem., 298, 2022
7VYW
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Crystal structure of the chromodomain of Arabidopsis LHP1 in complex with methylated histone H3K9 peptide
分子名称: Chromo domain-containing protein LHP1, SULFATE ION, methylated histone H3K9 peptide
著者Liu, Y, Zhang, M, Min, J.
登録日2021-11-15
公開日2022-02-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for the recognition of methylated histone H3 by the Arabidopsis LHP1 chromodomain.
J.Biol.Chem., 298, 2022
7UVE
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Drosophila melanogaster setdb1-tuor domain with peptide H3K9me2K14ac
分子名称: Histone-lysine N-methyltransferase eggless, peptide H3K9me2K14ac
著者Zhou, M, Dong, A, Liu, K, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2022-05-01
公開日2022-08-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Drosophila melanogaster setdb1-tuor domain with peptide H3K9me2K14ac
To Be Published
7UBU
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Crystal structure of ZMET2 in complex with hemimethylated CAG DNA and a histone H3Kc9me2 peptide
分子名称: 5MC SSDNA, C49 SSDNA, DNA (cytosine-5)-methyltransferase 1, ...
著者Fang, J, Song, J.
登録日2022-03-15
公開日2022-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Mechanistic basis for maintenance of CHG DNA methylation in plants.
Nat Commun, 13, 2022
7EF3
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crystal structure of maize SHH2 SAWADEE domain in complex with H3K9me2 peptide
分子名称: HB transcription factor, Histone H3.2, ZINC ION
著者Wang, Y, Du, J.
登録日2021-03-20
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recognition of H3K9me1 by maize RNA-directed DNA methylation factor SHH2.
J Integr Plant Biol, 63, 2021
6Z2A
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BU of 6z2a by Molmil
Structure of Clr4 mutant - F256A/F310A/F427A bound to SAH
分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific, MAGNESIUM ION, ...
著者Stirpe, A, Schalch, T.
登録日2020-05-15
公開日2021-05-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.456 Å)
主引用文献SUV39 SET domains mediate crosstalk of heterochromatic histone marks.
Elife, 10, 2021
6IE7
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Crystal structure of ADCP1 tandem Agenet domain 1-2 in complex with H3K9me2
分子名称: AMMONIUM ION, Agenet domain-containing protein, H3K9me2 peptide
著者Zhao, S, Zhang, B, Li, H.
登録日2018-09-13
公開日2019-01-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献ADCP1-tandem Agenet domain 1-2 in complex wit h H3K9me2
Cell Res., 29, 2019
6IE6
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Crystal structure of ADCP1 tandem Agenet domain 3-4 in complex with H3K9me2
分子名称: Agenet domain-containing protein, H3K9me2
著者Zhao, S, Zhang, B, Li, H.
登録日2018-09-13
公開日2019-01-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献ADCP1-tandem Agenet domain 1-2 in complex wit h H3K9me2
Cell Res., 29, 2019
6IE5
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BU of 6ie5 by Molmil
Crystal structure of ADCP1 tandem Agenet domain 3-4
分子名称: Agenet domain-containing protein
著者Zhao, S, Zhang, B, Li, H.
登録日2018-09-13
公開日2019-01-16
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献ADCP1-tandem Agenet domain 1-2 in complex wit h H3K9me2
Cell Res., 29, 2019
6IE4
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Crystal structure of ADCP1 tandem Agenet domain 1-2 in complex with H3K9me1
分子名称: Agenet domain-containing protein, H3K9me1 peptide
著者Zhao, S, Zhang, B, Li, H.
登録日2018-09-13
公開日2019-01-16
実験手法X-RAY DIFFRACTION (2.696 Å)
主引用文献ADCP1-tandem Agenet domain 1-2 in complex wit h H3K9me2
Cell Res., 29, 2019
6A5N
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BU of 6a5n by Molmil
Crystal structure of Arabidopsis thaliana SUVH6 in complex with methylated DNA
分子名称: DNA (5'-D(*CP*AP*CP*TP*GP*CP*TP*GP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*TP*AP*CP*TP*(5CM)P*AP*GP*CP*AP*GP*T)-3'), Histone-lysine N-methyltransferase, ...
著者Li, X, Du, J.
登録日2018-06-24
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6A5M
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Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 2
分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ...
著者Li, X, Du, J.
登録日2018-06-24
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6A5K
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BU of 6a5k by Molmil
Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1
分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ...
著者Li, X, Du, J.
登録日2018-06-24
公開日2018-08-29
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZWZ
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BU of 5zwz by Molmil
Crystal structure of Arabidopsis thaliana AGDP1 AGD34
分子名称: Agenet domain-containing protein
著者Du, X, Du, J.
登録日2018-05-17
公開日2018-11-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Arabidopsis AGDP1 links H3K9me2 to DNA methylation in heterochromatin
Nat Commun, 9, 2018
5ZWX
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Crystal structure of Raphanus sativus AGDP1 AGD12 in complex with an H3K9me2 peptide
分子名称: DUF724 domain-containing protein 6-like, H3(1-15)K9me2 peptide
著者Du, X, Du, J.
登録日2018-05-17
公開日2018-11-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Arabidopsis AGDP1 links H3K9me2 to DNA methylation in heterochromatin
Nat Commun, 9, 2018

 

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