PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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7M5L	PCNA bound to peptide mimetic with linker 分子名称: PROPANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen 著者 Vandborg, B.A, Bruning, J.B. 登録日 2021-03-24 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
5FG4	Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe 分子名称: 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide, Peregrin 著者 Tallant, C, Owen, D.R, Gerstenberger, B.S, Savitsky, P, Chaikuad, A, Fedorov, O, Nunez-Alonso, G, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Knapp, S. 登録日 2015-12-20 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe To Be Published
6KMK	Crystal structure of hydrogen peroxide bound bovine lactoperoxidase at 2.3 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HYDROGEN PEROXIDE, ... 著者 Singh, P.K, Sirohi, H.V, Bhusan, A, Kaur, P, Sharma, S, Singh, T.P. 登録日 2019-07-31 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of hydrogen peroxide bound bovine lactoperoxidase at 2.3 A resolution To Be Published
6OZJ	Crystal structure of Mus musculus (Mm) Endonuclease V in complex with a 23mer RNA oligo containing an inosine in the absence of divalent cation 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.247 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6DOG	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 600 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.285 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
7QZ6	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7M5N	PCNA bound to peptide mimetic with linker 分子名称: 1,3-dimethylbenzene, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen 著者 Vandborg, B.A, Bruning, J.B. 登録日 2021-03-24 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
6DEF	Vps1 GTPase-BSE fusion complexed with GMPPCP 分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Vps1 GTPase-BSE 著者 Ford, M.G.J, Varlakhanova, N.V, Brady, T.M, Chappie, J.S, Hosford, C.J. 登録日 2018-05-11 公開日 2018-08-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture. J. Cell Biol., 217, 2018
6FNQ	Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N,N-trimethylhistidine (hercynine) 分子名称: GLYCEROL, Histidine N-alpha-methyltransferase, MAGNESIUM ION, ... 著者 Vit, A, Blankenfeldt, W, Seebeck, F.P. 登録日 2018-02-05 公開日 2018-06-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD. ACS Chem. Biol., 13, 2018
6OZQ	Crystal structure of Mus musculus (Mm) Endonuclease V (K155M) in complex with a 23mer RNA oligo containing an inosine after a 100 min soak in 10 mM Mn2+ and K+ 分子名称: 1,2-ETHANEDIOL, DNA/RNA (5'-R(P*CP*GP*GP*UP*AP*AP*CP*CP*C)-D(P*I)-R(P*AP*UP*AP*UP*GP*CP*AP*UP*GP*CP*AP*UP*U)-3'), Endonuclease V, ... 著者 Samara, N.L, Yang, W. 登録日 2019-05-15 公開日 2019-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.153 Å) 主引用文献 Evolution of Inosine-Specific Endonuclease V from Bacterial DNase to Eukaryotic RNase. Mol.Cell, 76, 2019
6KNI	Crystal structure of SbnH in complex with the cofactor PLP, a PLP-dependent decarboxylase in Staphyloferrin B biothesynthesis 分子名称: PYRIDOXAL-5'-PHOSPHATE, Probable diaminopimelate decarboxylase protein 著者 Tang, J, Ju, Y, Zhou, H. 登録日 2019-08-05 公開日 2019-11-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural Insights into Substrate Recognition and Activity Regulation of the Key Decarboxylase SbnH in Staphyloferrin B Biosynthesis. J.Mol.Biol., 431, 2019
6DOU	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 5 mM Mg2+ and 200 mM Rb+ for 120 s at 21 C 分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', 5'-R(P*CP*G)-3' portion of cleaved RNA 5'-R(*AP*CP*AP*UP*CP*G)-3', ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.487 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
7MJ6	HLA-A*02:01 bound to Neuroblastoma Derived IGFBPL1 peptide 分子名称: Beta-2-microglobulin, GLYCEROL, Insulin-like growth factor-binding protein-like 1 peptide, ... 著者 Toor, J.S, Tripathi, S.M, Truong, H.V, Yarmarkovich, M, Maris, J.M, Sgourakis, N.G. 登録日 2021-04-19 公開日 2021-08-18 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs. Nature, 599, 2021
7R05	ATAD2 in complex with PepLite-Ile 分子名称: (2~{S},3~{S})-2-acetamido-~{N}-(3-bromanylprop-2-ynyl)-3-methyl-pentanamide, 1,2-ETHANEDIOL, ATPase family AAA domain-containing protein 2, ... 著者 Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. 登録日 2022-02-01 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions. J.Med.Chem., 65, 2022
6DP7	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 500 mM Mn2+ and 200 mM K+ for 40 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), IODIDE ION, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.381 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
6P0K	Crystal structure of GDP-bound human RalA in a covalent complex with aryl sulfonyl fluoride compounds. 分子名称: 4-[(6-chloropyridin-2-yl)sulfamoyl]benzene-1-sulfonic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Bum-Erdene, K, Gonzalez-Gutierrez, G, Liu, D, Ghozayel, M.K, Xu, D, Meroueh, S.O. 登録日 2019-05-17 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases. Proc.Natl.Acad.Sci.USA, 117, 2020
6FZH	Crystal structure of a streptococcal dehydrogenase at 1.5 Angstroem resolution 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ... 著者 Gomez, S, Querol-Garcia, J, Sanchez-Barron, G, Subias, M, Gonzalez-Alsina, A, Melchor-Tafur, C, Franco-Hidalgo, V, Alberti, S, Rodriguez de Cordoba, S, Fernandez, F.J, Vega, M.C. 登録日 2018-03-14 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Antimicrobials Anacardic Acid and Curcumin Are Not-Competitive Inhibitors of Gram-Positive Bacterial Pathogenic Glyceraldehyde-3-Phosphate Dehydrogenase by a Mechanism Unrelated to Human C5a Anaphylatoxin Binding. Front Microbiol, 10, 2019
7RHO	Human IgG1 Fc fragment, hinge-free, expressed in E. coli 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fc fragment of human IgG1 著者 Gallagher, D.T. 登録日 2021-07-18 公開日 2022-11-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Effects of glycans and hinge on dynamics in the IgG1 Fc. J.Biomol.Struct.Dyn., 2023
6DFJ	Crystal structure of anti-Zika antibody Z021 bound to DENV-1 envelope protein DIII 分子名称: Dengue 1 Envelope DIII domain, anti-Zika antibody Z021, Heavy Chain, ... 著者 Keeffe, J.R, Bjorkman, P.J. 登録日 2018-05-14 公開日 2018-10-24 最終更新日 2018-11-14 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates. Cell Rep, 25, 2018
6P0O	Crystal structure of GDP-bound human RalA 分子名称: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Ral-A 著者 Bum-Erdene, K, Gonzalez-Gutierrez, G, Liu, D, Ghozayel, M.K, Xu, D, Meroueh, S.O. 登録日 2019-05-17 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Small-molecule covalent bond formation at tyrosine creates a binding site and inhibits activation of Ral GTPases. Proc.Natl.Acad.Sci.USA, 117, 2020
5FHD	Structure of Bacteroides sp Pif1 complexed with tailed dsDNA resulting in ssDNA bound complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*CP*GP*GP*GP*GP*CP*CP*GP*CP*GP*C)-3'), MAGNESIUM ION, ... 著者 Zhou, X, Ren, W, Bharath, S.R, Song, H. 登録日 2015-12-22 公開日 2016-03-30 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1 Cell Rep, 14, 2016
6DPN	Crystal Structure of Bacillus Halodurans Ribonuclease H1 E188A in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 200 s at 21 C 分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.493 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
5FJC	SAM-I riboswitch bearing the H. marismortui Kt-7 variant C-2bU 分子名称: BARIUM ION, MAGNESIUM ION, POTASSIUM ION, ... 著者 Huang, L, Lilley, D.M.J. 登録日 2015-10-07 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function. Nucleic Acids Res., 44, 2016
8TCZ	Structure of PYCR1 complexed with 2-(pyridin-2-yl)cyclopropane-1-carboxylic acid 分子名称: (1S,2S)-2-(pyridin-2-yl)cyclopropane-1-carboxylic acid, Pyrroline-5-carboxylate reductase 1, mitochondrial, ... 著者 Tanner, J.J, Meeks, K.R. 登録日 2023-07-02 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography. J.Chem.Inf.Model., 64, 2024
7QZ8	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022

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