PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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8TCU	Structure of PYCR1 complexed with 2-chloro-5-(2-oxoimidazolidin-1-yl)benzoic acid 分子名称: 2-chloro-5-(2-oxoimidazolidin-1-yl)benzoic acid, Pyrroline-5-carboxylate reductase 1, mitochondrial, ... 著者 Tanner, J.J, Meeks, K.R. 登録日 2023-07-02 公開日 2024-03-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography. J.Chem.Inf.Model., 64, 2024
5FKD	SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is UA 分子名称: BARIUM ION, POTASSIUM ION, S-ADENOSYLMETHIONINE, ... 著者 Huang, L, Lilley, D.M.J. 登録日 2015-10-15 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function. Nucleic Acids Res., 44, 2016
5WSB	Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, allosteric activators AMP and Glucose 6-Phosphate 分子名称: 6-O-phosphono-alpha-D-glucopyranose, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... 著者 Zhong, W, Cai, Q, El Sahili, A, Lescar, J, Dedon, P.C. 登録日 2016-12-06 公開日 2017-11-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis. Nat Commun, 8, 2017
8BI6	Crystal structure of human Choline Kinase A in complex with UNC0638 分子名称: 1,2-ETHANEDIOL, 2-cyclohexyl-6-methoxy-N-[1-(1-methylethyl)piperidin-4-yl]-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine, CHLORIDE ION, ... 著者 Diaz-Saez, L, Ward, J, Kennedy, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Huber, K, Structural Genomics Consortium (SGC) 登録日 2022-11-01 公開日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of human Choline Kinase A in complex with UNC0638 To Be Published
6FUN	F11 T-Cell Receptor Recognising PKYVKQNTLKLAT Peptide Presented by HLA-DR*0101 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Human F11 T-Cell Receptor alpha chain, ... 著者 Rizkallah, P.J, Cole, D.K. 登録日 2018-02-27 公開日 2018-04-18 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 In Silicoand Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility. Front Immunol, 9, 2018
7RMN	Crystal structure of triosephosphate isomerase from Verrucomicrobium spinosum 分子名称: Triosephosphate isomerase 著者 Vickers, C.J, Fraga, D, Patrick, W.M. 登録日 2021-07-27 公開日 2022-08-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Structure of VspTPI - Verrucomicrobium spinosum triosephoshate isomerase To be published
6KGK	LSD1-CoREST-S2101 five-membered ring adduct model 分子名称: 3-[3,5-bis(fluoranyl)-2-phenylmethoxy-phenyl]propanal, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Niwa, H, Sato, S, Sengoku, S, Umehara, T, Yokoyama, S. 登録日 2019-07-12 公開日 2020-03-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Development and Structural Evaluation of N-Alkylated trans-2-Phenylcyclopropylamine-Based LSD1 Inhibitors. Chemmedchem, 15, 2020
7ROM	Crystal structure of Saccharomyces cerevisiae NADH-cytochrome b5 reductase 1 (Cbr1) fragment (residues 28-284) bound to FAD 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NADH-cytochrome b5 reductase 1, ... 著者 Fenwick, M.K, Zhang, Y, Lin, H. 登録日 2021-07-31 公開日 2022-08-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of Saccharomyces cerevisiae NADH-cytochrome b5 reductase 1 (Cbr1) fragment (residues 28-284) bound to FAD To Be Published
6DJW	Crystal Structure of pParkin (REP and RING2 deleted)-pUb-UbcH7 complex 分子名称: RBR-type E3 ubiquitin transferase,RBR-type E3 ubiquitin transferase, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... 著者 Sauve, V, Sung, G, Trempe, J.F, Gehring, K. 登録日 2018-05-26 公開日 2018-07-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.801 Å) 主引用文献 Mechanism of parkin activation by phosphorylation. Nat. Struct. Mol. Biol., 25, 2018
8BF0	Structure of a Fab portion from TKH2 分子名称: Anti-dectin-1 15E2 light chain, Anti-lox-1 15C4 heavy chain, CITRIC ACID, ... 著者 Diskin, R, Borenstein-Katz, A. 登録日 2022-10-23 公開日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of a Fab portion from TKH2 To Be Published
7RQ0	HIV Integrase CORE domain in complex with 2-{2-[2-(3-{[4-(2-{[(3-{2-[3-(carboxymethyl)-5-methyl-1-benzofuran-2-yl]ethynyl}phenyl)methyl]amino}ethyl)piperazin-1-yl]methyl}phenyl)ethynyl]-5-methyl-1-benzofuran-3-yl}acetic acid 分子名称: IODIDE ION, Integrase, SULFATE ION, ... 著者 Gorman, M.A, Parker, M.W. 登録日 2021-08-05 公開日 2022-08-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 HIV integrase-LEDGF interaction screening by fragment linking using off-rate screening To Be Published
8TFO	Structure of MKvar 分子名称: (R)-MEVALONATE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Peat, T.S, Newman, J, Esquirol, L, Nebl, T, Scott, C, Vickers, C, Sainsbury, F. 登録日 2023-07-11 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Characterization of novel mevalonate kinases from the tardigrade Ramazzottius varieornatus and the psychrophilic archaeon Methanococcoides burtonii. Acta Crystallogr D Struct Biol, 80, 2024
6FVE	Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound FITC 分子名称: 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(E)-(sulfanylmethylidene)amino]benzoic acid, Macrophage migration inhibitory factor, SULFATE ION 著者 Samygina, V.R, Bourenkov, G, Sokolov, A.V. 登録日 2018-03-02 公開日 2018-06-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor. Biochemistry Mosc., 83, 2018
8TFU	Structure of Red beta C-terminal domain in complex with SSB C-terminal peptide, Form 1 分子名称: Plasmid-derived single-stranded DNA-binding protein, Recombination protein bet 著者 Bell, C.E. 登録日 2023-07-11 公開日 2024-03-13 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.482 Å) 主引用文献 Structural Basis for the Interaction of Red beta Single-Strand Annealing Protein with Escherichia coli Single-Stranded DNA-Binding Protein. J.Mol.Biol., 436, 2024
7R0X	Structure of the branching thioesterase from oocydin biosynthesis 分子名称: Polyketide synthase 著者 Fraley, A.E, Piel, J. 登録日 2022-02-02 公開日 2022-08-10 最終更新日 2022-09-28 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Structure of a Promiscuous Thioesterase Domain Responsible for Branching Acylation in Polyketide Biosynthesis. Angew.Chem.Int.Ed.Engl., 61, 2022
6DKK	Structure of BoNT 分子名称: Botulinum neurotoxin type A, PHOSPHATE ION 著者 Lam, K, Jin, R. 登録日 2018-05-29 公開日 2018-12-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1. Nat Commun, 9, 2018
5G0B	An unusual natural product primary sulfonamide: synthesis, carbonic anhydrase inhibition and protein x-ray structure of Psammaplin C 分子名称: CARBONIC ANHYDRASE 2, CHLORIDE ION, GLYCEROL, ... 著者 Mujumdar, P, Supuran, C.T, Peat, T.S, Poulsen, S.A. 登録日 2016-03-17 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition and Protein X-Ray Structures of Psammaplin C. J.Med.Chem., 59, 2016
5W74	Crystal Structure of the Group II Chaperonin from Methanococcus Maripaludis D386ADeltaLid Mutant in the Open, ADP-Bound State 分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperonin, MAGNESIUM ION 著者 Dalton, K.M, Lopez, T, Liu, C, Ralston, C.Y, Pereira, J.H, Chartron, J.W, McAndrew, R.P, Douglas, N.R, Adams, P.D, Pande, V.S, Frydman, J. 登録日 2017-06-19 公開日 2018-06-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 The Conformational Cycle of the Group II Chaperonin Termini To Be Published
7RPP	Crystal structure of human CEACAM1 with GFCC' and ABED face 分子名称: 1,2-ETHANEDIOL, Carcinoembryonic antigen-related cell adhesion molecule 1 著者 Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Petsko, G.A, Blumberg, R.S. 登録日 2021-08-04 公開日 2022-08-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural analysis of human CEACAM1 oligomerization. Commun Biol, 5, 2022
6DKV	Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 21 round 5 分子名称: 5-nitro-2-oxidanyl-benzenecarbonitrile, DI(HYDROXYETHYL)ETHER, Kemp eliminase KE07 著者 Jackson, C.J, Hong, N.-S, Carr, P.D. 登録日 2018-05-30 公開日 2018-08-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 The evolution of multiple active site configurations in a designed enzyme. Nat Commun, 9, 2018
5W8N	Lipid A Disaccharide Synthase (LpxB)-6 solubilizing mutations 分子名称: Lipid-A-disaccharide synthase 著者 Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. 登録日 2017-06-22 公開日 2018-01-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli. Nat Commun, 9, 2018
5FNH	Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination 分子名称: 5-[(3-chloranylphenoxy)methyl]-1,2,4-triaza-3-azanidacyclopenta-1,4-diene, CARBONIC ANHYDRASE 2, DIMETHYL SULFOXIDE, ... 著者 Woods, L.A, Dolezal, O, Ren, B, Ryan, J.H, Peat, T.S, Poulsen, S.A. 登録日 2015-11-15 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59, 2016
7LMC	Structure of SARS CoV-2 main protease shows simultaneous processing of its N- and C-terminii 分子名称: 3C-like proteinase, Non-structural protein 4 peptide 著者 Gajiwala, K.S, Ferre, R.A, Liu, W, Ryan, K. 登録日 2021-02-05 公開日 2021-04-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.977 Å) 主引用文献 SARS coronavirus-2 main protease dimer auto-processes N-terminus in cis and C-terminus in trans To Be Published
6DL0	Crystal structure of pohlianin C, an orbitide from Jatropha pohliana 分子名称: pohlianin C 著者 Wang, C.K, King, G.J, Ramalho, S.D. 登録日 2018-05-31 公開日 2018-11-07 最終更新日 2023-07-26 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Synthesis, Racemic X-ray Crystallographic, and Permeability Studies of Bioactive Orbitides from Jatropha Species. J. Nat. Prod., 81, 2018
5FHB	Crystal Structure of Protective Ebola Virus Antibody 100 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Antibody 100 Fab heavy chain, ... 著者 Gilman, M.S.A, McLellan, J.S. 登録日 2015-12-21 公開日 2016-03-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.973 Å) 主引用文献 Structural and molecular basis for Ebola virus neutralization by protective human antibodies. Science, 351, 2016

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