PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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5UBG	Catalytic core domain of Adenosine triphosphate phosphoribosyltransferase from Campylobacter jejuni with bound Phosphoribosyl-ATP 分子名称: ATP phosphoribosyltransferase, CHLORIDE ION, PHOSPHORIBOSYL ATP, ... 著者 Mittelstaedt, G, Jiao, W, Livingstone, E.K, Parker, E.J. 登録日 2016-12-20 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase. Biochem. J., 475, 2018
6R5P	The crystal structure of Glycoside Hydrolase BglX inactive mutant D286N from P. aeruginosa in complex with glucose 分子名称: MAGNESIUM ION, Periplasmic beta-glucosidase, beta-D-glucopyranose 著者 Batuecas, M.T, Hermoso, J.A. 登録日 2019-03-25 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Catalytic Cycle of Glycoside Hydrolase BglX fromPseudomonas aeruginosaand Its Implications for Biofilm Formation. Acs Chem.Biol., 15, 2020
7R8R	Physachenolide C with Bromodomain (BRD3-BD1) 分子名称: Bromodomain-containing protein 3, Physachenolide C 著者 Fromme, R, Sivinski, J, Zerio, C, Gunatilaka, A.A.L, Chapman, E. 登録日 2021-06-27 公開日 2022-09-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Physachenolide C is a Potent, Selective BET Inhibitor. J.Med.Chem., 66, 2023
6DVC	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
6DVU	Structure of the Monoclinic-1 (Monocl-1) Crystal Form of Human Apolipoprotein C1 分子名称: Apolipoprotein C-I 著者 McPherson, A, Larson, S.B. 登録日 2018-06-25 公開日 2018-12-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structure of human apolipoprotein C-1 in four different crystal forms. J. Lipid Res., 60, 2019
7M8R	Complex structure of Methane monooxygenase hydroxylase and regulatory subunit with fluorosubstituted tryptophans 分子名称: 1,1,1-tris(fluoranyl)propan-2-one, 1,2-ETHANEDIOL, BENZOIC ACID, ... 著者 Johns, J.C, Banerjee, R, Shi, K, Semonis, M.M, Aihara, H, Pomerantz, W.C.K, Lipscomb, J.D. 登録日 2021-03-30 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Soluble Methane Monooxygenase Component Interactions Monitored by 19 F NMR. Biochemistry, 60, 2021
7A9U	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)-N-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)propanamide 分子名称: 1,2-ETHANEDIOL, 3-(3-(but-3-yn-1-yl)-3H-diazirin-3-yl)-N-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-8-yl)propanamide, Bromodomain-containing protein 4 著者 Chung, C. 登録日 2020-09-02 公開日 2020-10-21 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.444 Å) 主引用文献 A Photoaffinity-Based Fragment-Screening Platform for Efficient Identification of Protein Ligands. Angew.Chem.Int.Ed.Engl., 59, 2020
8BR0	ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin (residue Q3455 to L3863) in complex with 3'deoxyCTP and two manganese cations bound to Latrunculin-B-ADP-Mn-actin 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Actin, ... 著者 Texeira-Nuns, M, Retailleau, P, Renault, L. 登録日 2022-11-22 公開日 2023-09-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.218 Å) 主引用文献 Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin. Plos Pathog., 19, 2023
7R4L	Crystal structure of human mitochondrial NAD kinase 分子名称: FE (III) ION, NAD kinase 2, mitochondrial, ... 著者 Labesse, G, Mary, C, Gelin, M, Lionne, C. 登録日 2022-02-08 公開日 2022-07-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82, 2022
6ICF	The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA12 tag inserted between the residues 263 and 266 分子名称: Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ... 著者 Tamura, R, Oi, R, Kaneko, M.K, Kato, Y, Nogi, T. 登録日 2018-09-05 公開日 2019-02-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Application of the NZ-1 Fab as a crystallization chaperone for PA tag-inserted target proteins. Protein Sci., 28, 2019
8QA8	Crystal structure of the C-terminally truncated transcriptional repressor protein KorB from the RK2 plasmid complexed with CTP-gamma-S 分子名称: CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, Transcriptional repressor protein KorB 著者 McLean, T.C, Mundy, J.E.A, Lawson, D.M, Le, T.B.K. 登録日 2023-08-22 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the C-terminally truncated transcriptional repressor protein KorB from the RK2 plasmid complexed with CTP-gamma-S To Be Published
7RPA	X-ray crystal structure of OXA-24/40 K84D in complex with meropenem 分子名称: (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, BICARBONATE ION, Beta-lactamase, ... 著者 Powers, R.A, Mitchell, J.M, June, C.M. 登録日 2021-08-03 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Conformational flexibility in carbapenem hydrolysis drives substrate specificity of the class D carbapenemase OXA-24/40. J.Biol.Chem., 298, 2022
5HO1	MamB-CTD 分子名称: Magnetosome protein MamB, ZINC ION 著者 Keren, N, Zarivach, R. 登録日 2016-01-19 公開日 2017-02-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 The dual role of MamB in magnetosome membrane assembly and magnetite biomineralization. Mol. Microbiol., 107, 2018
5HQG	WD40 domain of Human E3 Ubiquitin Ligase COP1 (RFWD2) 分子名称: E3 ubiquitin-protein ligase RFWD2 著者 Uljon, S, Blacklow, S.C. 登録日 2016-01-21 公開日 2016-04-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for Substrate Selectivity of the E3 Ligase COP1. Structure, 24, 2016
7R7M	Crystal structure of Triosephosphate isomerase from Candidate division Katanobacteria (WWE3) bacterium 分子名称: PHOSPHATE ION, Triosephosphate isomerase 著者 Vickers, C.J, Patrick, W.M, Fraga, D. 登録日 2021-06-24 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of WweTPI - Candidate division WWE3 To Be Published
7MFL	Structure of the Clostridium perfringens GH89 in complex with beta-HNJNAc 分子名称: 1,2-ETHANEDIOL, Alpha-N-acetylglucosaminidase family protein, CALCIUM ION, ... 著者 Boraston, A.B. 登録日 2021-04-09 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Iminosugar C-Glycosides Work as Pharmacological Chaperones of NAGLU, a Glycosidase Involved in MPS IIIB Rare Disease*. Chemistry, 27, 2021
6R2U	Zinc-alpha2-Glycoprotein with a Fluorescent Dansyl C 11 Fatty Acid 分子名称: 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid, AZIDE ION, SULFATE ION, ... 著者 Lau, A.M, Gor, J, Perkins, S.J, Coker, A.R, McDermott, L.C. 登録日 2019-03-18 公開日 2019-09-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Crystal structure of zinc-alpha 2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding. Biochem.J., 476, 2019
6GDQ	Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of ERK1/2 分子名称: 4-[5-chloranyl-2-(propan-2-ylamino)pyridin-4-yl]-~{N}-[(1~{S})-1-(3-chlorophenyl)-2-oxidanyl-ethyl]-1~{H}-pyrrole-2-carboxamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 O'Reilly, M. 登録日 2018-04-24 公開日 2018-05-30 最終更新日 2018-06-27 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J. Med. Chem., 61, 2018
7RBP	Medicago truncatula D-1-piperideine-2-carboxylic acid reductase 分子名称: Ornithine cyclodeaminase/mu-crystallin 著者 Torrens-spence, M.P, Weng, J.K. 登録日 2021-07-06 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Pipecolic acid pathway is conserved in systemic acquired resistance between dicotyledon and monocotyledon plants To Be Published
5UBP	TREX2 M-region 分子名称: 26S proteasome complex subunit SEM1, Leucine permease transcriptional regulator, Nuclear mRNA export protein THP1 著者 Stewart, M, Gordon, J. 登録日 2016-12-21 公開日 2017-04-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex. Nucleic Acids Res., 45, 2017
7AAU	Crystal structure of nitrosoglutathione reductase from Chlamydomonas reinhardtii in complex with NAD+ 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Fermani, S, Zaffagnini, M, Falini, G, Lemaire, S.D. 登録日 2020-09-04 公開日 2020-12-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Structural and functional insights into nitrosoglutathione reductase from Chlamydomonas reinhardtii. Redox Biol, 38, 2020
6G84	Structure of Cdc14 bound to CBK1 PxL motif 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CBK1, ... 著者 Mouilleron, S, Kataria, M, Uhlmann, F. 登録日 2018-04-07 公開日 2018-10-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase. Nat. Struct. Mol. Biol., 25, 2018
7RP9	X-ray crystal structure of OXA-24/40 V130D in complex with imipenem 分子名称: (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid, BICARBONATE ION, Beta-lactamase, ... 著者 Powers, R.A, Mitchell, J.M, June, C.M. 登録日 2021-08-03 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Conformational flexibility in carbapenem hydrolysis drives substrate specificity of the class D carbapenemase OXA-24/40. J.Biol.Chem., 298, 2022
8QZD	Soluble epoxide hydrolase in complex with Epoxykinin 分子名称: 1,2-ETHANEDIOL, 2-[5-bromanyl-3-[2,2,2-tris(fluoranyl)ethanoyl]indol-1-yl]-N-cycloheptyl-ethanamide, BROMIDE ION, ... 著者 Kumar, A, Ehrler, J.M.H, Ziegler, S, Doetsch, L, Proschak, E, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2023-10-27 公開日 2024-02-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator. J.Med.Chem., 67, 2024
7ACG	In meso structure of the alginate exporter, AlgE, from Pseudomonas aeruginosa in 9.8 monoacylglycerol 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 2-(2-METHOXYETHOXY)ETHANOL, Alginate biosynthesis protein AlgE, ... 著者 Smithers, L, van Dalsen, L, Boland, C, Caffrey, M. 登録日 2020-09-10 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 9.8 MAG. A new host lipid for in meso (lipid cubic phase) crystallization of integral membrane proteins Cryst.Growth Des., 2020

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