1PM9
 
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3O8A
 | | Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with novel Inhibitor Genz667348 | | 分子名称: | Dihydroorotate dehydrogenase homolog, mitochondrial, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Deng, X, Booker, M.L, Phillips, M.A. | | 登録日 | 2010-08-02 | | 公開日 | 2010-08-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Novel inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase with anti-malarial activity in the mouse model.
J.Biol.Chem., 285, 2010
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3NY8
 | | Crystal structure of the human beta2 adrenergic receptor in complex with the inverse agonist ICI 118,551 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]butan-2-ol, Beta-2 adrenergic receptor, ... | | 著者 | Wacker, D, Fenalti, G, Brown, M.A, Katritch, V, Abagyan, R, Cherezov, V, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | | 登録日 | 2010-07-14 | | 公開日 | 2010-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Conserved Binding Mode of Human beta(2) Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
J.Am.Chem.Soc., 132, 2010
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1K9W
 | | HIV-1(MAL) RNA Dimerization Initiation Site | | 分子名称: | HIV-1 DIS(Mal)UU RNA, MAGNESIUM ION | | 著者 | Ennifar, E, Walter, P, Ehresmann, B, Ehresmann, C, Dumas, P. | | 登録日 | 2001-10-31 | | 公開日 | 2001-11-30 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site.
Nat.Struct.Biol., 8, 2001
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1F30
 | | THE STRUCTURAL BASIS FOR DNA PROTECTION BY E. COLI DPS PROTEIN | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA PROTECTION DURING STARVATION PROTEIN, ZINC ION | | 著者 | Luo, J, Liu, D, White, M.A, Fox, R.O. | | 登録日 | 2000-05-31 | | 公開日 | 2003-06-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The Structural Basis for DNA Protection by E. coli Dps Protein
To be Published
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2WV3
 | | Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NEUROPLASTIN | | 著者 | Soroka, V, Owczarek, S, Kastrup, J.S, Berezin, V, Bock, E, Gajhede, M. | | 登録日 | 2009-10-13 | | 公開日 | 2009-12-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Neuroplastin-55 Binds to and Signals Through the Fibroblast Growth Factor Receptor
Faseb J., 24, 2010
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1A5N
 | | K217A VARIANT OF KLEBSIELLA AEROGENES UREASE, CHEMICALLY RESCUED BY FORMATE AND NICKEL | | 分子名称: | FORMIC ACID, NICKEL (II) ION, UREASE (ALPHA SUBUNIT), ... | | 著者 | Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. | | 登録日 | 1998-02-17 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
Biochemistry, 37, 1998
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2WQ3
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3VPG
 | | L-lactate dehydrogenase from Thermus caldophilus GK24 | | 分子名称: | GLYCEROL, L-lactate dehydrogenase | | 著者 | Arai, K, Ohno, T, Miyanaga, A, Fushinobu, S, Taguchi, H. | | 登録日 | 2012-03-01 | | 公開日 | 2013-03-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The core of allosteric motion in Thermus caldophilus L-lactate dehydrogenase.
J.Biol.Chem., 2014
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6T8G
 | | Stalled FtsK motor domain bound to dsDNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA translocase FtsK, dsDNA substrate | | 著者 | Jean, N.L, Lowe, J. | | 登録日 | 2019-10-24 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.34 Å) | | 主引用文献 | FtsK in motion reveals its mechanism for double-stranded DNA translocation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6DDE
 | | Mu Opioid Receptor-Gi Protein Complex | | 分子名称: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Koehl, A, Hu, H, Maeda, S, Manglik, A, Zhang, Y, Kobilka, B.K, Skiniotis, G, Weis, W.I. | | 登録日 | 2018-05-10 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of the mu-opioid receptor-Giprotein complex.
Nature, 558, 2018
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1KC2
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3W1T
 | | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-095 | | 分子名称: | 2,6-dioxo-5-{2-[3-(trifluoromethyl)phenyl]ethyl}-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid, COBALT HEXAMMINE(III), Dihydroorotate dehydrogenase (fumarate), ... | | 著者 | Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Matsuoka, S, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. | | 登録日 | 2012-11-21 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-3-095
To be Published
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1AJC
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1UA6
 | | Crystal structure of HYHEL-10 FV MUTANT SFSF complexed with HEN EGG WHITE LYSOZYME complex | | 分子名称: | Ig VH,anti-lysozyme, Lysozyme C, lysozyme binding Ig kappa chain V23-J2 region | | 著者 | Kumagai, I, Nishimiya, Y, Kondo, H, Tsumoto, K. | | 登録日 | 2003-02-28 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural consequences of target epitope-directed functional alteration of an antibody. The case of anti-hen lysozyme antibody, HyHEL-10
J.Biol.Chem., 278, 2003
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1F12
 | | L-3-HYDROXYACYL-COA DEHYDROGENASE COMPLEXED WITH 3-HYDROXYBUTYRYL-COA | | 分子名称: | 3-HYDROXYBUTANOYL-COENZYME A, L-3-HYDROXYACYL-COA DEHYDROGENASE | | 著者 | Barycki, J.J, O'Brien, L.K, Strauss, A.W, Banaszak, L.J. | | 登録日 | 2000-05-18 | | 公開日 | 2000-09-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase.
J.Biol.Chem., 275, 2000
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1EZR
 | | CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR | | 分子名称: | CALCIUM ION, NUCLEOSIDE HYDROLASE | | 著者 | Shi, W, Schramm, V.L, Almo, S.C. | | 登録日 | 2000-05-11 | | 公開日 | 2000-05-24 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure.
J.Biol.Chem., 274, 1999
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1ANJ
 | | ALKALINE PHOSPHATASE (K328H) | | 分子名称: | ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION | | 著者 | Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R. | | 登録日 | 1995-09-06 | | 公開日 | 1996-01-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
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1A5K
 | | K217E VARIANT OF KLEBSIELLA AEROGENES UREASE | | 分子名称: | UREASE (ALPHA SUBUNIT), UREASE (BETA SUBUNIT), UREASE (GAMMA SUBUNIT) | | 著者 | Pearson, M.A, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. | | 登録日 | 1998-02-17 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Chemical rescue of Klebsiella aerogenes urease variants lacking the carbamylated-lysine nickel ligand.
Biochemistry, 37, 1998
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4HP8
 | | Crystal structure of a putative 2-deoxy-d-gluconate 3-dehydrogenase from Agrobacterium Tumefaciens (target EFI-506435) with bound NADP | | 分子名称: | 2-deoxy-D-gluconate 3-dehydrogenase, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Vetting, M.W, Bouvier, J.T, Groninger-Poe, F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2012-10-23 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Crystal structure of a putative 2-deoxy-d-gluconate 3-dehydrogenase from Agrobacterium Tumefaciens (target EFI-506435) with bound NADP
To be Published
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3VRB
 | | Mitochondrial rhodoquinol-fumarate reductase from the parasitic nematode Ascaris suum with the specific inhibitor flutolanil and substrate fumarate | | 分子名称: | Cytochrome b-large subunit, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | | 著者 | Shimizu, H, Shiba, T, Inaoka, D.K, Osanai, A, Kita, K, Sakamoto, K, Harada, S. | | 登録日 | 2012-04-07 | | 公開日 | 2012-07-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Crystal structure of mitochondrial quinol-fumarate reductase from the parasitic nematode Ascaris suum
J.Biochem., 151, 2012
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6DKS
 | | Structure of the Rbpj-SHARP-DNA Repressor Complex | | 分子名称: | DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | | 著者 | Kovall, R.A, VanderWielen, B.D, Yuan, Z. | | 登録日 | 2018-05-30 | | 公開日 | 2019-01-02 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site.
Cell Rep, 26, 2019
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1F4T
 | | THERMOPHILIC P450: CYP119 FROM SULFOLOBUS SOLFACTARICUS WITH 4-PHENYLIMIDAZOLE BOUND | | 分子名称: | 4-PHENYL-1H-IMIDAZOLE, CYTOCHROME P450 119, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Yano, J.K, Koo, L.S, Schuller, D.J, Li, H, Ortiz de Montellano, P.R, Poulos, T.L. | | 登録日 | 2000-06-09 | | 公開日 | 2000-10-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus.
J.Biol.Chem., 275, 2000
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1AJB
 | | THREE-DIMENSIONAL STRUCTURE OF THE D153G MUTANT OF E. COLI ALKALINE PHOSPHATASE: A MUTANT WITH WEAKER MAGNESIUM BINDING AND INCREASED CATALYTIC ACTIVITY | | 分子名称: | ALKALINE PHOSPHATASE, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Dealwis, C.G, Chen, L, Abad-Zapatero, C. | | 登録日 | 1995-08-19 | | 公開日 | 1995-11-14 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | 3-D structure of the D153G mutant of Escherichia coli alkaline phosphatase: an enzyme with weaker magnesium binding and increased catalytic activity.
Protein Eng., 8, 1995
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1ANI
 | | ALKALINE PHOSPHATASE (D153H, K328H) | | 分子名称: | ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION | | 著者 | Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R. | | 登録日 | 1995-09-06 | | 公開日 | 1996-01-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases.
J.Mol.Biol., 253, 1995
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