PDB: 35863 件ウェブページステータス検索Chemie searchBIRD

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4NME	Crystal structure of proline utilization A (PutA) from Geobacter sulfurreducens PCA inactivated by N-propargylglycine 分子名称: 1,2-ETHANEDIOL, N-propargylglycine-modified flavin adenine dinucleotide, Proline dehydrogenase and Delta-1-pyrroline-5-carboxylate dehydrogenase 著者 Singh, H, Tanner, J.J. 登録日 2013-11-14 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.088 Å) 主引用文献 Structures of the PutA peripheral membrane flavoenzyme reveal a dynamic substrate-channeling tunnel and the quinone-binding site. Proc.Natl.Acad.Sci.USA, 111, 2014
4NRE	The structure of human 15-lipoxygenase-2 with a substrate mimic 分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Arachidonate 15-lipoxygenase B, CALCIUM ION, ... 著者 Kobe, M.J, Neau, D.B, Mitchell, C.E, Bartlett, S.G, Newcomer, M.E. 登録日 2013-11-26 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 The structure of human 15-lipoxygenase-2 with a substrate mimic. J.Biol.Chem., 289, 2014
4YVV	Crystal structure of AKR1C3 complexed with glibenclamide 分子名称: 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Zhao, Y, Zheng, X, Zhang, H, Hu, X. 登録日 2015-03-20 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis Chem.Biol.Interact., 240, 2015
4NSH	Carboplatin binding to HEWL in 0.2M NH4SO4, 0.1M NaAc in 25% PEG 4000 at pH 4.6 分子名称: ACETATE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... 著者 Tanley, S.W.M, Diederichs, K, Kroon-Batenburg, L.M.J, Levy, C, Schreurs, A.M.M, Helliwell, J.R. 登録日 2013-11-28 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Carboplatin binding to histidine. Acta Crystallogr F Struct Biol Commun, 70, 2014
4YGF	Crystal structure of the complex of Helicobacter pylori alpha-Carbonic Anhydrase with acetazolamide 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Alpha-carbonic anhydrase, CHLORIDE ION, ... 著者 Roujeinikova, A, Modak, J.K. 登録日 2015-02-26 公開日 2015-07-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Basis for the Inhibition of Helicobacter pylori alpha-Carbonic Anhydrase by Sulfonamides. Plos One, 10, 2015
4NEV	Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor EP127 (5-{5-[1-(PYRROLIDIN-1-YL)CYCLOHEXYL]-1,3-THIAZOL-2-YL}-1H-INDOLE) 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-1,3-thiazol-2-yl}-1H-indole, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Persch, E, Bryson, S, Pai, E.F, Krauth-Siegel, R.L, Diederich, F. 登録日 2013-10-30 公開日 2014-05-14 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductase. Chemmedchem, 9, 2014
4Y9U	rat CYPOR mutant - G143del 分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Xia, C, Kim, J.J.P. 登録日 2015-02-17 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone. J.Biol.Chem., 291, 2016
4YA4	Yeast 20S proteasome beta2-H114D mutant 分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Huber, E.M, Groll, M. 登録日 2015-02-17 公開日 2015-06-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. J.Am.Chem.Soc., 137, 2015
4NGK	Previously de-ionized HEW lysozyme batch crystallized in 0.2 M CoCl2 分子名称: CHLORIDE ION, COBALT (II) ION, Lysozyme C 著者 Benas, P, Legrand, L, Ries-Kautt, M. 登録日 2013-11-02 公開日 2014-05-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Weak protein-cationic co-ion interactions addressed by X-ray crystallography and mass spectrometry. Acta Crystallogr.,Sect.D, 70, 2014
4YMK	Crystal Structure of Stearoyl-Coenzyme A Desaturase 1 分子名称: Acyl-CoA desaturase 1, STEAROYL-COENZYME A, ZINC ION, ... 著者 Bai, Y, McCoy, J.G, Rajashankar, K.R, Zhou, M. 登録日 2015-03-06 公開日 2015-06-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 X-ray structure of a mammalian stearoyl-CoA desaturase. Nature, 524, 2015
4NHY	Crystal structure of human OGFOD1, 2-oxoglutarate and iron-dependent oxygenase domain containing 1, in complex with pyridine-2,4-dicarboxylic acid (2,4-PDCA) 分子名称: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1, GLYCEROL, MANGANESE (II) ION, ... 著者 Horita, S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.603 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
4YEO	Triclinic HEWL co-crystallised with cisplatin, studied at a data collection temperature of 150K - new refinement 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Cisplatin, ... 著者 Shabalin, I.G, Dauter, Z, Jaskolski, M, Minor, W, Wlodawer, A. 登録日 2015-02-24 公開日 2015-03-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin. Acta Crystallogr.,Sect.D, 71, 2015
4YFA	Structure of N-acylhomoserine lactone acylase MacQ in complex with decanoic acid 分子名称: DECANOIC ACID, Protein related to penicillin acylase 著者 Yasutake, Y, Kusada, H, Kimura, N. 登録日 2015-02-25 公開日 2016-03-02 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Bifunctional quorum-quenching and antibiotic-acylase MacQ forms a 170-kDa capsule-shaped molecule containing spacer polypeptides Sci Rep, 7, 2017
4NHK	Crystal structure of Tpa1p from Saccharomyces cerevisiae, termination and polyadenylation protein 1, in complex with pyridine-2,4-dicarboxylic acid (2,4-PDCA) 分子名称: GLYCEROL, MANGANESE (II) ION, PKHD-type hydroxylase TPA1, ... 著者 Scotti, J.S, McDonough, M.A, Schofield, C.J. 登録日 2013-11-05 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of the Ribosomal Oxygenase OGFOD1 Provides Insights into the Regio- and Stereoselectivity of Prolyl Hydroxylases. Structure, 23, 2015
4XAQ	mGluR2 ECD and mGluR3 ECD with ligands 分子名称: (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, CHLORIDE ION, Metabotropic glutamate receptor 2, ... 著者 Clawson, D.K. 登録日 2014-12-15 公開日 2015-02-04 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures. J.Med.Chem., 58, 2015
4XB3	Structure of dextran glucosidase 分子名称: CALCIUM ION, Glucan 1,6-alpha-glucosidase, HEXAETHYLENE GLYCOL 著者 Kobayashi, M, Kato, K, Yao, M. 登録日 2014-12-16 公開日 2015-08-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.093 Å) 主引用文献 Structural insights into the catalytic reaction that is involved in the reorientation of Trp238 at the substrate-binding site in GH13 dextran glucosidase Febs Lett., 589, 2015
4XET	Fe-Cl bound Y157F CDO at pH ~7.0 in the presence of azide 分子名称: CHLORIDE ION, Cysteine dioxygenase type 1, FE (III) ION 著者 Driggers, C.M, Karplus, P.A. 登録日 2014-12-24 公開日 2016-04-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
4XF0	cysteine dioxygenase variant - C93A at pH 8.0 with cysteine 分子名称: CHLORIDE ION, CYSTEINE, Cysteine dioxygenase type 1, ... 著者 Driggers, C.M, Karplus, P.A. 登録日 2014-12-25 公開日 2016-03-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3994 Å) 主引用文献 Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
4XGV	Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. 登録日 2015-01-02 公開日 2015-12-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.883 Å) 主引用文献 Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm. Microbiologyopen, 5, 2016
4XHY	NADH:FMN oxidoreductase from Paracoccus denitrificans 分子名称: Flavin reductase domain protein, FMN-binding protein 著者 Sedlacek, V, Klumpler, T, Marek, J, Kucera, I. 登録日 2015-01-06 公開日 2016-01-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Biochemical properties and crystal structure of the flavin reductase FerA from Paracoccus denitrificans. Microbiol. Res., 188-189, 2016
4XII	X-ray structure of human butyrylcholinesterase in complex with N-((1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl)methyl)-8-hydroxy-N-(2-methoxyethyl)-5-nitroquinoline-7-carboxamide 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Knez, D, Boris, B, Coquelle, N, Sosic, I, Sink, R, Brazzolotto, X, Mravljak, J, Colletier, J.P, Gobec, S. 登録日 2015-01-07 公開日 2015-07-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents. Bioorg.Med.Chem., 23, 2015
4XIW	Carbonic anhydrase Cah3 from Chlamydomonas reinhardtii in complex with acetazolamide 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase, alpha type, ... 著者 Hainzl, T, Grundstrom, C, Benlloch, R, Shevela, D, Shutova, T, Messinger, J, Samuelsson, G, Sauer-Eriksson, A.E. 登録日 2015-01-07 公開日 2015-02-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure and Functional Characterization of Photosystem II-Associated Carbonic Anhydrase CAH3 in Chlamydomonas reinhardtii. Plant Physiol., 167, 2015
4XAG	Cycles of destabilization and repair underlie the evolution of new enzyme function 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-R6, ... 著者 Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. 登録日 2014-12-14 公開日 2015-12-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The role of protein dynamics in the evolution of new enzyme function. Nat.Chem.Biol., 12, 2016
4M11	Crystal Structure of Murine Cyclooxygenase-2 Complex with Meloxicam 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, ... 著者 Xu, S, Banerjee, S, Hermanson, D.J, Marnett, L.J. 登録日 2013-08-02 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network. J.Biol.Chem., 289, 2014
4XFG	cysteine dioxygenase variant - C93A at pH 6.2 with cysteine 分子名称: CHLORIDE ION, CYSTEINE, Cysteine dioxygenase type 1, ... 著者 Driggers, C.M, Karplus, P.A. 登録日 2014-12-26 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.401 Å) 主引用文献 Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016

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