PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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4CWS	Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor 分子名称: 2-{[2-amino-5-(1,3-benzodioxol-5-ylmethyl)[1,2,4]triazolo[1,5-c]quinazolin-8-yl]amino}ethanol, HEAT SHOCK PROTEIN HSP 90-ALPHA 著者 Casale, E, Amboldi, N, Brasca, G, Caronni, D, Colombo, N, Dalvit, C, Felder, E.R, Fogliatto, G, Isacchi, A, Mantegani, S, Polucci, P, Riceputi, L, Sola, F, Visco, C, Zuccotto, F, Casuscelli, F. 登録日 2014-04-03 公開日 2014-07-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment-Based Hit Discovery and Structure-Based Optimization of Aminotriazoloquinazolines as Novel Hsp90 Inhibitors. Bioorg.Med.Chem., 22, 2014
4JJQ	Crystal structure of usp7-ntd with an e2 enzyme 分子名称: Ubiquitin carboxyl-terminal hydrolase 7, Ubiquitin-conjugating enzyme E2 E1 著者 Saridakis, V. 登録日 2013-03-08 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1. J. Biol. Chem., 288, 2013
3OXQ	Crystal Structure of Ca2+/CaM-CaV1.2 pre-IQ/IQ domain complex 分子名称: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C 著者 Kim, E.Y, Rumpf, C.H, Van Petegem, F, Arant, R, Findeisen, F, Cooley, E.S, Isacoff, E.Y, Minor, D.L. 登録日 2010-09-21 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization. Embo J., 29, 2010
1NNF	Crystal Structure Analysis of Haemophlius Influenzae Ferric-ion Binding Protein H9Q Mutant Form 分子名称: FE (III) ION, Iron-utilization periplasmic protein, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID 著者 Shouldice, S.R, Dougan, D.R, Skene, R.J, Tari, L.W, McRee, D.E, Yu, R.-H, Schryvers, A.B. 登録日 2003-01-13 公開日 2003-04-01 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 High Resolution Structure of an Alternate Form of the Ferric ion Binding Protein from Haemophilus influenzae J.Biol.Chem., 278, 2003
1NRK	YGFZ PROTEIN 分子名称: SULFATE ION, YGFZ Protein 著者 Teplyakov, A, Obmolova, G, Gilliland, G.L, Structure 2 Function Project (S2F) 登録日 2003-01-24 公開日 2004-03-09 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the YgfZ protein from Escherichia coli suggests a folate-dependent regulatory role in one-carbon metabolism. J.Bacteriol., 186, 2004
1NUA	Crystal structure of 3-dehydroquinate synthase (DHQS) in complex with ZN2+ 分子名称: 3-DEHYDROQUINATE SYNTHASE, CHLORIDE ION, ZINC ION 著者 Nichols, C.E, Ren, J, Lamb, H.K, Hawkins, A.R, Stammers, D.K. 登録日 2003-01-31 公開日 2003-03-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Ligand-induced Conformational Changes and a Mechanism for Domain Closure in Aspergillus nidulans Dehydroquinate Synthase J.MOL.BIOL., 327, 2003
4CMV	Crystal structure of Rv3378c 分子名称: CITRIC ACID, DITERPENE SYNTHASE, MERCURY (II) ION 著者 Layre, E, Lee, H.J, Young, D.C, Martinot, A.J, Buter, J, Minnaard, A.J, Annand, J.W, Fortune, S.M, Snider, B.B, Matsunaga, I, Rubin, E.J, Alber, T, Moody, D.B. 登録日 2014-01-18 公開日 2014-02-19 最終更新日 2014-03-12 実験手法 X-RAY DIFFRACTION (2.307 Å) 主引用文献 Molecular Profiling of Mycobacterium Tuberculosis Identifies Tuberculosinyl Nucleoside Products of the Virulence-Associated Enzyme Rv3378C. Proc.Natl.Acad.Sci.USA, 111, 2014
1JF2	Crystal Structure of W92F obelin mutant from Obelia longissima at 1.72 Angstrom resolution 分子名称: C2-HYDROPEROXY-COELENTERAZINE, obelin 著者 Liu, Z.-J, Vysotski, E.S, Deng, L, Markova, S.V, Lee, J, Rose, J.P, Wang, B.-C. 登録日 2001-06-19 公開日 2001-07-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Violet bioluminescence and fast kinetics from W92F obelin: structure-based proposals for the bioluminescence triggering and the identification of the emitting species. Biochemistry, 42, 2003
4L8M	Human p38 MAP kinase in complex with a Dibenzoxepinone 分子名称: Mitogen-activated protein kinase 14, N-[2-fluoro-5-({9-[2-(morpholin-4-yl)ethoxy]-11-oxo-6,11-dihydrodibenzo[b,e]oxepin-3-yl}amino)phenyl]benzamide, octyl beta-D-glucopyranoside 著者 Richters, A, Mayer-Wrangowski, S.C, Gruetter, C, Rauh, D. 登録日 2013-06-17 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Metabolically Stable Dibenzo[b,e]oxepin-11(6H)-ones as Highly Selective p38 MAP Kinase Inhibitors: Optimizing Anti-Cytokine Activity in Human Whole Blood. J.Med.Chem., 56, 2013
1O8K	Pectate Lyase C from Erwinia Chrysanthemi at pH 4.5 with 20mM CA2+ 分子名称: CALCIUM ION, PECTATE LYASE C 著者 Herron, S.R, Jurnak, F.A. 登録日 2002-11-27 公開日 2003-01-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Characterization and Implications of Ca2+ Binding to Pectate Lyase C J.Biol.Chem., 278, 2003
1NZG	Crystal structure of A-DNA decamer GCGTA(3ME)ACGC, with a modified 5-methyluridine 分子名称: 5'-D(*GP*CP*GP*TP*AP*(3ME)P*AP*CP*GP*C)-3' 著者 Prhavc, M, Prakash, T.P, Minasov, G, Egli, M, Manoharan, M. 登録日 2003-02-17 公開日 2003-08-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects Org.Lett., 5, 2003
1NRA	SOLUTION STRUCTURE OF AN OLD WORLD-LIKE NEUROTOXIN FROM THE VENOM OF THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING 分子名称: NEUROTOXIN V, CSE-V 著者 Jablonsky, M.J, Krishna, N.R. 登録日 1995-01-03 公開日 1995-02-27 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of an Old World-like neurotoxin from the venom of the New World scorpion Centruroides sculpturatus Ewing. J.Mol.Biol., 248, 1995
4DN8	Structure of porcine surfactant protein D neck and carbohydrate recognition domain complexed with mannose 分子名称: CALCIUM ION, Pulmonary surfactant-associated protein D, beta-D-mannopyranose 著者 van Eijk, M, Rynkiewicz, M.J, White, M.R, Hartshorn, K.L, Zou, X, Schulten, K, Luo, D, Crouch, E.C, Cafarella, T.M, Head, J.F, Haagsman, H.P, Seaton, B.A. 登録日 2012-02-08 公開日 2012-06-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A Unique Sugar-binding Site Mediates the Distinct Anti-influenza Activity of Pig Surfactant Protein D. J.Biol.Chem., 287, 2012
4DZT	Aqualysin I: the crystal structure of a serine protease from an extreme thermophile, Thermus aquaticus YT-1 分子名称: Aqualysin-1, CALCIUM ION, phenylmethanesulfonic acid 著者 Barnett, B.L, Green, P.R, Strickland, L.C, Oliver, J.D, Rydel, T, Sullivan, J.F. 登録日 2012-03-01 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Aqualysin I: the crystal structure of a serine protease from an extreme thermophile, Thermus aquaticus YT-1 To be Published
4L1Y	Crystal structure of Cimex nitrophorin A21V mutant 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Salivary nitrophorin 著者 Badgandi, H.B, Weichsel, A, Montfort, W.R. 登録日 2013-06-04 公開日 2014-09-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Proximal Cysteine Protonation in Cimex Nitrophorin is key to efficient NO transport and release. To be Published
1NMK	The Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data 分子名称: (13E,15E)-(3S,6S,9R,10R,11S,12S,18S,21S)-10,12-DIHYDROXY-3-(3-HYDROXYBEN-ZYL)-18-((E)-3-HYDROXY-1-METHYLPROPENYL)-6-ISOPROPYL-11-METHYL-9-(3-OXO-BUTYL)-19-OXA-1,4,7,25-TETRAAZA-BICYCLO[19.3.1]PENTACOSA-13,15-DIENE-2,5,8,20-TETRAONE, Peptidyl-prolyl cis-trans isomerase A 著者 Kallen, J, Sedrani, R, Wagner, J. 登録日 2003-01-10 公開日 2003-04-01 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data J.Am.Chem.Soc., 125, 2003
1O5F	Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA) 分子名称: 2-{5-[AMINO(IMINIO)METHYL]-6-FLUORO-1H-BENZIMIDAZOL-2-YL}-6-[(2-METHYLCYCLOHEXYL)OXY]BENZENOLATE, Serine protease hepsin 著者 Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E. 登録日 2003-09-09 公開日 2004-09-21 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA). J.Mol.Biol., 344, 2004
1NVU	Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Margarit, S.M, Sondermann, H, Hall, B.E, Nagar, B, Hoelz, A, Pirruccello, M, Bar-Sagi, D, Kuriyan, J. 登録日 2003-02-04 公開日 2003-04-01 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS Cell(Cambridge,Mass.), 112, 2003
4DNQ	Crystal Structure of DAD2 S96A mutant 分子名称: DAD2 著者 Hamiaux, C. 登録日 2012-02-08 公開日 2012-11-14 最終更新日 2013-06-26 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 DAD2 Is an alpha/beta Hydrolase likely to Be Involved in the Perception of the Plant Branching Hormone, Strigolactone Curr.Biol., 22, 2012
4JNU	Crystal structure of the human Nup57CCS3* coiled-coil segment, space group P21 分子名称: Nucleoporin p54 著者 Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A. 登録日 2013-03-15 公開日 2014-09-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.445 Å) 主引用文献 Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015
1TDY	DISSECTION OF THE FUNCTIONAL ROLE OF STRUCTURAL ELEMENTS OF TYROSINE-63 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME 分子名称: HUMAN LYSOZYME 著者 Harata, K, Muraki, M, Jigami, Y. 登録日 1992-08-06 公開日 1993-01-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Dissection of the functional role of structural elements of tyrosine-63 in the catalytic action of human lysozyme. Biochemistry, 31, 1992
1P0Z	Sensor Kinase CitA binding domain 分子名称: CITRATE ANION, MO(VI)(=O)(OH)2 CLUSTER, SODIUM ION, ... 著者 Reinelt, S, Hofmann, E, Gerharz, T, Bott, M, Madden, D.R. 登録日 2003-04-11 公開日 2003-08-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The structure of the periplasmic ligand-binding domain of the sensor kinase CitA reveals the first extracellular PAS domain. J.Biol.Chem., 278, 2003
1M7D	Crystal structure of a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide complexed with a trisaccharide 分子名称: alpha-L-rhamnopyranose-(1-3)-alpha-L-Olivopyranose-(1-3)-methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, heavy chain of the monoclonal antibody Fab SYA/J6, light chain of the monoclonal antibody Fab SYA/J6 著者 Vyas, N.K, Vyas, M.N, Chervenak, M.C, Johnson, M.A, Pinto, B.M, Bundle, D.R, Quiocho, F.A. 登録日 2002-07-19 公開日 2003-07-22 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Recognition of Oligosaccharide Epitopes by a Monoclonal Fab Specific for Shigella flexneri Y Lipopolysaccharide: X-ray Structures and Thermodynamics Biochemistry, 41, 2002
1OYW	Structure of the RecQ Catalytic Core 分子名称: ATP-dependent DNA helicase, MANGANESE (II) ION, ZINC ION 著者 Bernstein, D.A, Zittel, M.C, Keck, J.L. 登録日 2003-04-07 公開日 2003-10-07 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High-resolution structure of the E. coli RecQ helicase catalytic core Embo J., 22, 2003
1P5E	The structure of phospho-CDK2/cyclin A in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole (TBS) 分子名称: 4,5,6,7-TETRABROMOBENZOTRIAZOLE, Cell division protein kinase 2, Cyclin A2 著者 De Moliner, E, Brown, N.R, Johnson, L.N. 登録日 2003-04-26 公開日 2003-07-01 最終更新日 2016-12-21 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Alternative binding modes of an inhibitor to two different kinases Eur.J.Biochem., 270, 2003

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