1KMS
 
 | | HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 6-([5-QUINOLYLAMINO]METHYL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE (SRI-9439), A LIPOPHILIC ANTIFOLATE | | 分子名称: | 6-([5-QUINOLYLAMINO]METHYL)-2,4-DIAMINO-5-METHYLPYRIDO[2,3-D]PYRIMIDINE, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Klon, A.E, Heroux, A, Ross, L.J, Pathak, V, Johnson, C.A, Piper, J.R, Borhani, D.W. | | 登録日 | 2001-12-17 | | 公開日 | 2002-07-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution.
J.Mol.Biol., 320, 2002
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1KLD
 | | SOLUTION STRUCTURE OF TGF-B1, NMR, MODELS 18-33 OF 33 STRUCTURES | | 分子名称: | TRANSFORMING GROWTH FACTOR-BETA 1 | | 著者 | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | | 登録日 | 1996-01-16 | | 公開日 | 1996-08-17 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2.
Biochemistry, 35, 1996
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4HW6
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4HL5
 | | Complex structure of human tankyrase 2 with 7-hydroxy -4'-methoxyflavone | | 分子名称: | 7-hydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | | 著者 | Narwal, M, Haikarainen, T, Lehtio, L. | | 登録日 | 2012-10-16 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Screening and structural analysis of flavones inhibiting tankyrases.
J.Med.Chem., 56, 2013
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4NAZ
 | | Crystal Structure of FosB from Staphylococcus aureus with Zn and Sulfate at 1.15 Angstrom Resolution | | 分子名称: | GLYCEROL, Metallothiol transferase FosB, SULFATE ION, ... | | 著者 | Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Cook, P.D, Armstrong, R.N. | | 登録日 | 2013-10-22 | | 公開日 | 2014-02-26 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus.
Biochemistry, 53, 2014
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1PCA
 | | THREE DIMENSIONAL STRUCTURE OF PORCINE PANCREATIC PROCARBOXYPEPTIDASE A. A COMPARISON OF THE A AND B ZYMOGENS AND THEIR DETERMINANTS FOR INHIBITION AND ACTIVATION | | 分子名称: | CITRIC ACID, PROCARBOXYPEPTIDASE A PCPA, VALINE, ... | | 著者 | Guasch, A, Coll, M, Aviles, F.X, Huber, R. | | 登録日 | 1991-10-28 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structure of porcine pancreatic procarboxypeptidase A. A comparison of the A and B zymogens and their determinants for inhibition and activation.
J.Mol.Biol., 224, 1992
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3W3A
 | | Crystal structure of V1-ATPase at 3.9 angstrom resolution | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | | 著者 | Nagamatsu, Y, Takeda, K, Kuranaga, T, Numoto, N, Miki, K. | | 登録日 | 2012-12-14 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Origin of Asymmetry at the Intersubunit Interfaces of V1-ATPase from Thermusthermophilus
J.Mol.Biol., 425, 2013
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1PSF
 | | THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF PSAE FROM THE CYANOBACTERIUM SYNECHOCOCCUS SP. STRAIN PCC 7002: A PHOTOSYSTEM I PROTEIN THAT SHOWS STRUCTURAL HOMOLOGY WITH SH3 DOMAINS | | 分子名称: | PHOTOSYSTEM I ACCESSORY PROTEIN E | | 著者 | Falzone, C.J, Kao, Y.-H, Zhao, J, Bryant, D.A, Lecomte, J.T.J. | | 登録日 | 1994-04-13 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of PsaE from the cyanobacterium Synechococcus sp. strain PCC 7002, a photosystem I protein that shows structural homology with SH3 domains.
Biochemistry, 33, 1994
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1PSE
 | | THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF PSAE FROM THE CYANOBACTERIUM SYNECHOCOCCUS SP. STRAIN PCC 7002: A PHOTOSYSTEM I PROTEIN THAT SHOWS STRUCTURAL HOMOLOGY WITH SH3 DOMAINS | | 分子名称: | PHOTOSYSTEM I ACCESSORY PROTEIN E | | 著者 | Falzone, C.J, Kao, Y.-H, Zhao, J, Bryant, D.A, Lecomte, J.T.J. | | 登録日 | 1994-04-13 | | 公開日 | 1995-04-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of PsaE from the cyanobacterium Synechococcus sp. strain PCC 7002, a photosystem I protein that shows structural homology with SH3 domains.
Biochemistry, 33, 1994
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1PRU
 | | PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING | | 分子名称: | PURINE REPRESSOR | | 著者 | Nagadoi, A, Morikawa, S, Nakamura, H, Enari, M, Kobayashi, K, Yamamoto, H, Sampei, G, Mizobuchi, K, Schumacher, M.A, Brennan, R.G, Nishimura, Y. | | 登録日 | 1995-05-08 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
Structure, 3, 1995
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1PRV
 | | PURINE REPRESSOR DNA-BINDING DOMAIN DNA BINDING | | 分子名称: | PURINE REPRESSOR | | 著者 | Nagadoi, A, Morikawa, S, Nakamura, H, Enari, M, Kobayashi, K, Yamamoto, H, Sampei, G, Mizobuchi, K, Schumacher, M.A, Brennan, R.G, Nishimura, Y. | | 登録日 | 1995-05-08 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural comparison of the free and DNA-bound forms of the purine repressor DNA-binding domain.
Structure, 3, 1995
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1KU5
 | | Crystal Structure of recombinant histone HPhA from hyperthermophilic archaeon Pyrococcus horikoshii OT3 | | 分子名称: | ACETATE ION, HPhA, SULFATE ION | | 著者 | Li, T, Sun, F, Ji, X, Feng, Y, Rao, Z. | | 登録日 | 2002-01-21 | | 公開日 | 2003-08-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure based hyperthermostability of archaeal histone HPhA from Pyrococcus horikoshii
J.MOL.BIOL., 325, 2003
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1QPD
 | | STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS | | 分子名称: | LCK KINASE, STAUROSPORINE, SULFATE ION | | 著者 | Zhu, X, Kim, J.L, Rose, P.E, Stover, D.R, Toledo, L.M, Zhao, H, Morgenstern, K.A. | | 登録日 | 1999-05-24 | | 公開日 | 2000-05-24 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.
Structure Fold.Des., 7, 1999
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4I1N
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1QSV
 | | THE VEGF-BINDING DOMAIN OF FLT-1, 20 NMR STRUCTURES | | 分子名称: | VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 | | 著者 | Starovasnik, M.A, Christinger, H.W, Wiesmann, C, Champe, M.A, de Vos, A.M, Skelton, N.J. | | 登録日 | 1999-06-23 | | 公開日 | 1999-11-10 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the VEGF-binding domain of Flt-1: comparison of its free and bound states.
J.Mol.Biol., 293, 1999
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3O5X
 | | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor | | 分子名称: | 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J. | | 登録日 | 2010-07-28 | | 公開日 | 2010-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
J.Med.Chem., 53, 2010
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4CWR
 | | Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor | | 分子名称: | 5-(1,3-benzodioxol-5-ylmethyl)-10-fluoro[1,2,4]triazolo[1,5-c]quinazolin-2-amine, HEAT SHOCK PROTEIN HSP 90-ALPHA | | 著者 | Casale, E, Amboldi, N, Brasca, G, Caronni, D, Colombo, N, Dalvit, C, Felder, E.R, Fogliatto, G, Isacchi, A, Mantegani, S, Polucci, P, Riceputi, L, Sola, F, Visco, C, Zuccotto, F, Casuscelli, F. | | 登録日 | 2014-04-03 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Fragment-Based Hit Discovery and Structure-Based Optimization of Aminotriazoloquinazolines as Novel Hsp90 Inhibitors.
Bioorg.Med.Chem., 22, 2014
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1ZNF
 | | THREE-DIMENSIONAL SOLUTION STRUCTURE OF A SINGLE ZINC FINGER DNA-BINDING DOMAIN | | 分子名称: | 31ST ZINC FINGER FROM XFIN, ZINC ION | | 著者 | Lee, M.S, Gippert, G.P, Soman, K.V, Case, D.A, Wright, P.E. | | 登録日 | 1989-09-25 | | 公開日 | 1991-07-15 | | 最終更新日 | 2017-11-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of a single zinc finger DNA-binding domain.
Science, 245, 1989
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1QS9
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1QH4
 | | CRYSTAL STRUCTURE OF CHICKEN BRAIN-TYPE CREATINE KINASE AT 1.41 ANGSTROM RESOLUTION | | 分子名称: | ACETATE ION, CALCIUM ION, CREATINE KINASE | | 著者 | Eder, M, Schlattner, U, Becker, A, Wallimann, T, Kabsch, W, Fritz-Wolf, K. | | 登録日 | 1999-05-11 | | 公開日 | 1999-11-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Crystal structure of brain-type creatine kinase at 1.41 A resolution.
Protein Sci., 8, 1999
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1QU9
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4LHL
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1QKL
 | | hRPABC14.4, essential subunit of human RNA polymerases I, II and III | | 分子名称: | DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE | | 著者 | Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G. | | 登録日 | 1999-07-26 | | 公開日 | 1999-11-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases
Nat.Struct.Biol., 6, 1999
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4HKN
 | | Complex structure of human tankyrase 2 with luteolin | | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, SULFATE ION, Tankyrase-2, ... | | 著者 | Narwal, M, Haikarainen, T, Lehtio, L. | | 登録日 | 2012-10-15 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Screening and structural analysis of flavones inhibiting tankyrases.
J.Med.Chem., 56, 2013
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4HL0
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