1PDO
| |
1JIA
| |
4HR7
| Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli | 分子名称: | 1,2-ETHANEDIOL, Biotin carboxyl carrier protein of acetyl-CoA carboxylase, Biotin carboxylase, ... | 著者 | Broussard, T.C, Kobe, M.J, Pakhomova, S, Neau, D.B, Price, A.E, Champion, T.S, Waldrop, G.L. | 登録日 | 2012-10-26 | 公開日 | 2013-03-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | 主引用文献 | The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase. Structure, 21, 2013
|
|
4HMH
| Crystal structure of tankyrase 2 in complex with 7,3-dihydroxyflavone | 分子名称: | 7-hydroxy-2-(3-hydroxyphenyl)-4H-chromen-4-one, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Narwal, M, Haikarainen, T, Lehtio, L. | 登録日 | 2012-10-18 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
|
|
1K7C
| |
4HLF
| Crystal structure of Tankyrase 2 in complex with 7,3',4'-Trihydroxyflavone | 分子名称: | 2-(3,4-dihydroxyphenyl)-7-hydroxy-4H-chromen-4-one, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Narwal, M, Haikarainen, T, Lehtio, L. | 登録日 | 2012-10-17 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
|
|
1KBC
| PROCARBOXYPEPTIDASE TERNARY COMPLEX | 分子名称: | 3-AMINO-AZACYCLOTRIDECAN-2-ONE, 3-FORMYL-2-HYDROXY-5-METHYL-HEXANOIC ACID HYDROXYAMIDE, CALCIUM ION, ... | 著者 | Betz, M, Gomis-Rueth, F.X, Bode, W. | 登録日 | 1997-04-29 | 公開日 | 1997-08-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | 1.8-A crystal structure of the catalytic domain of human neutrophil collagenase (matrix metalloproteinase-8) complexed with a peptidomimetic hydroxamate primed-side inhibitor with a distinct selectivity profile. Eur.J.Biochem., 247, 1997
|
|
4M69
| Crystal structure of the mouse RIP3-MLKL complex | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Mixed lineage kinase domain-like protein, ... | 著者 | Xie, T, Peng, W, Yan, C, Wu, J, Shi, Y. | 登録日 | 2013-08-09 | 公開日 | 2013-10-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.497 Å) | 主引用文献 | Structural Insights into RIP3-Mediated Necroptotic Signaling Cell Rep, 5, 2013
|
|
4HLG
| Crystal structure of Tankyrase 2 in complex with 3'-hydroxyflavone | 分子名称: | 2-(3-hydroxyphenyl)-4H-chromen-4-one, GLYCEROL, SULFATE ION, ... | 著者 | Narwal, M, Haikarainen, T, Lehtio, L. | 登録日 | 2012-10-17 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
|
|
4EON
| Thr 160 phosphorylated CDK2 H84S, Q85M, Q131E - human cyclin A3 complex with the inhibitor RO3306 | 分子名称: | (5E)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one, Cyclin-A2, Cyclin-dependent kinase 2, ... | 著者 | Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D. | 登録日 | 2012-04-14 | 公開日 | 2013-02-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity. Chem.Biol., 19, 2012
|
|
1PTO
| |
4ERW
| CDK2 in complex with staurosporine | 分子名称: | 1,2-ETHANEDIOL, Cyclin-dependent kinase 2, STAUROSPORINE | 著者 | Alam, R, Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | 登録日 | 2012-04-20 | 公開日 | 2012-08-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem, 13, 2012
|
|
3O3R
| Crystal Structure of AKR1B14 in complex with NADP | 分子名称: | Aldo-keto reductase family 1, member B7, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Sundaram, K, Dhagat, U, El-Kabbani, O. | 登録日 | 2010-07-26 | 公開日 | 2011-01-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis Bioorg.Med.Chem.Lett., 21, 2011
|
|
1PXR
| Structure of Pro50Ala mutant of Bacteriorhodopsin | 分子名称: | Bacteriorhodopsin, RETINAL | 著者 | Faham, S, Yang, D, Bare, E, Yohannan, S, Whitelegge, J.P, Bowie, J.U. | 登録日 | 2003-07-06 | 公開日 | 2003-12-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Side-chain Contributions to Membrane Protein Structure and Stability. J.Mol.Biol., 335, 2004
|
|
1PY6
| Bacteriorhodopsin crystallized from bicells | 分子名称: | Bacteriorhodopsin, RETINAL | 著者 | Faham, S, Yang, D, Bare, E, Yohannan, S, Whitelegge, J.P, Bowie, J.U. | 登録日 | 2003-07-08 | 公開日 | 2003-12-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Side-chain Contributions to Membrane Protein Structure and Stability. J.Mol.Biol., 335, 2004
|
|
1PZC
| |
1UDX
| Crystal structure of the conserved protein TT1381 from Thermus thermophilus HB8 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, the GTP-binding protein Obg | 著者 | Kukimoto-Niino, M, Shirouzu, M, Murayama, K, Inoue, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-05-07 | 公開日 | 2004-03-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal structure of the GTP-binding protein Obg from Thermus thermophilus HB8. J.Mol.Biol., 337, 2004
|
|
4HKI
| Tankyrase 2 in complex with flavone | 分子名称: | 2-PHENYL-4H-CHROMEN-4-ONE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Narwal, M, Haikarainen, T, Lehtio, L. | 登録日 | 2012-10-15 | 公開日 | 2012-10-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Screening and structural analysis of flavones inhibiting tankyrases. J.Med.Chem., 56, 2013
|
|
1Q5I
| Crystal structure of bacteriorhodopsin mutant P186A crystallized from bicelles | 分子名称: | Bacteriorhodopsin, RETINAL | 著者 | Yohannan, S, Faham, S, Yang, D, Whitelegge, J.P, Bowie, J.U. | 登録日 | 2003-08-07 | 公開日 | 2004-01-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors. Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1PNH
| SOLUTION STRUCTURE OF PO5-NH2, A SCORPION TOXIN ANALOG WITH HIGH AFFINITY FOR THE APAMIN-SENSITIVE POTASSIUM CHANNEL | 分子名称: | SCORPION TOXIN | 著者 | Meunier, S, Bernassau, J.-M, Sabatier, J.-M, Martin-Eauclaire, M.-F, Van Rietschoten, J, Cambillau, C, Darbon, H. | 登録日 | 1993-08-25 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of P05-NH2, a scorpion toxin analog with high affinity for the apamin-sensitive potassium channel. Biochemistry, 32, 1993
|
|
4EOR
| Thr 160 phosphorylated CDK2 WT - human cyclin A3 complex with the inhibitor NU6102 | 分子名称: | Cyclin-A2, Cyclin-dependent kinase 2, O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE | 著者 | Echalier, A, Cot, E, Camasses, A, Hodimont, E, Hoh, F, Sheinerman, F, Krasinska, L, Fisher, D. | 登録日 | 2012-04-14 | 公開日 | 2013-02-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity. Chem.Biol., 19, 2012
|
|
1FLT
| |
1KLC
| SOLUTION STRUCTURE OF TGF-B1, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | TRANSFORMING GROWTH FACTOR-BETA 1 | 著者 | Hinck, A.P, Archer, S.J, Qian, S.W, Roberts, A.B, Sporn, M.B, Weatherbee, J.A, Tsang, M.L.-S, Lucas, R, Zhang, B.-L, Wenker, J, Torchia, D.A. | 登録日 | 1996-01-16 | 公開日 | 1996-08-17 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2. Biochemistry, 35, 1996
|
|
1YYF
| Correction of X-ray Intensities from an HslV-HslU co-crystal containing lattice translocation defects | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent hsl protease ATP-binding subunit hslU, ATP-dependent protease hslV | 著者 | Wang, J, Rho, S.H, Park, H.H, Eom, S.H. | 登録日 | 2005-02-24 | 公開日 | 2005-07-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (4.16 Å) | 主引用文献 | Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects. Acta Crystallogr.,Sect.D, 61, 2005
|
|
4N9O
| Probing the N-terminal beta-sheet conversion in the crystal structure of the human prion protein bound to a Nanobody | 分子名称: | Major prion protein, Nanobody Nb484 | 著者 | Abskharon, R.N.N, Giachin, G, Wohlkonig, A, Soror, S.H, Pardon, E, Legname, G, Steyaert, J. | 登録日 | 2013-10-21 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Probing the N-Terminal beta-Sheet Conversion in the Crystal Structure of the Human Prion Protein Bound to a Nanobody. J.Am.Chem.Soc., 136, 2014
|
|