PDB: 17153 件ウェブページステータス検索Chemie searchBIRD

---

7UJP	Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... 著者 Ozden, C, Foster, J.C, Stratton, M.M, Garman, S.C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
7UE8	PANK3 complex structure with compound PZ-3890 分子名称: 1,2-ETHANEDIOL, 1-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-(4-cyclopropyl-3-fluorophenyl)ethan-1-one, ACETATE ION, ... 著者 White, S.W, Yun, M, Lee, R.E. 登録日 2022-03-21 公開日 2023-03-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia. J Inherit Metab Dis, 46, 2023
7WNW	Crystal structure of Imine Reductase Mutant(M5) from Actinoalloteichus hymeniacidonis in complex with NADPH 分子名称: 3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Zhand, J, Chen, R, Gao, S. 登録日 2022-01-19 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure-Guided Engineering. Angew.Chem.Int.Ed.Engl., 61, 2022
7WNN	Crystal structure of Imine Reductase from Actinoalloteichus hymeniacidonis in complex with NADPH 分子名称: 3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Zhang, J, Chen, R, Gao, S. 登録日 2022-01-19 公開日 2022-04-06 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure-Guided Engineering. Angew.Chem.Int.Ed.Engl., 61, 2022
7KL1	Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ... 著者 Ozden, C, Stratton, M.M, Garman, S.C. 登録日 2020-10-28 公開日 2020-12-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
5IAN	Caspase 3 V266N 分子名称: ACE-ASP-GLU-VAL-ASK, Caspase-3, LEU-SER-SER, ... 著者 Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. 登録日 2016-02-21 公開日 2016-10-26 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
5IAE	Caspase 3 V266F 分子名称: ACE-ASP-GLU-VAL-ASK, ACETATE ION, CHLORIDE ION, ... 著者 Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. 登録日 2016-02-21 公開日 2016-10-26 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
5IBR	Caspase 3 V266K 分子名称: ACE-ASP-GLU-VAL-ASK, Caspase-3 著者 Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. 登録日 2016-02-22 公開日 2016-10-26 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
5IAG	Caspase 3 V266Q 分子名称: ACE-ASP-GLU-VAL-ASK, ASP-ASP-ASP-MET, Caspase-3 著者 Maciag, J.J, Mackenzie, S.H, Tucker, M.B, Schipper, J.L, Swartz, P.D, Clark, A.C. 登録日 2016-02-21 公開日 2016-10-26 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. Proc.Natl.Acad.Sci.USA, 113, 2016
7KL0	Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) 分子名称: 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ... 著者 Ozden, C, Stratton, M.M, Garman, S.C. 登録日 2020-10-28 公開日 2020-12-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 CaMKII binds both substrates and activators at the active site. Cell Rep, 40, 2022
5IUZ	STRUCTURE OF P450 2B4 F202W MUTANT (CYMAL-5) 分子名称: 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Jang, H.-H, Halpert, J.R, Shah, M.B. 登録日 2016-03-18 公開日 2016-06-08 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry. Biophys.Chem., 216, 2016
7L5M	Crystal Structure of the DiB-RM-split Protein 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lipocalin family protein, SODIUM ION, ... 著者 Bozhanova, N.G, Harp, J.M, Meiler, J. 登録日 2020-12-22 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Computational redesign of a fluorogen activating protein with Rosetta. Plos Comput.Biol., 17, 2021
7L5L	Crystal structure of the DiB-RM protein 分子名称: Lipocalin family protein, SULFATE ION 著者 Bozhanova, N.G, Harp, J.M, Meiler, J. 登録日 2020-12-22 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Computational redesign of a fluorogen activating protein with Rosetta. Plos Comput.Biol., 17, 2021
7L5K	Crystal structure of the DiB-RM protein 分子名称: DODECYL-BETA-D-MALTOSIDE, ISOPROPYL ALCOHOL, Lipocalin family protein, ... 著者 Bozhanova, N.G, Harp, J.M, Meiler, J. 登録日 2020-12-22 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Computational redesign of a fluorogen activating protein with Rosetta. Plos Comput.Biol., 17, 2021
7L4X	YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by two six-bp DNA duplexes in P3221 Crystal 分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA w/N6A 著者 Horton, J.R, Cheng, X. 登録日 2020-12-21 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions. Nucleic Acids Res., 49, 2021
7L4Y	YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by Two Six-bp DNA Duplexes in P212121 Crystal 分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA 13mer 著者 Horton, J.R, Cheng, X. 登録日 2020-12-21 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions. Nucleic Acids Res., 49, 2021
5JV3	The neck-linker and alpha 7 helix of Homo sapiens Eg5 fused to EB1 分子名称: CALCIUM ION, Chimera protein of Kinesin-like protein KIF11 and Microtubule-associated protein RP/EB family member 1 著者 Phillips, R.K, Rayment, I. 登録日 2016-05-10 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.006 Å) 主引用文献 Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil. J.Biol.Chem., 291, 2016
5JVS	The neck-linker + DAL and alpha 7 helix of Drosophila melanogaster Kinesin-1 fused to EB1 分子名称: 1,2-ETHANEDIOL, Chimera protein of Kinesin heavy chain and Microtubule-associated protein RP/EB family member 1, ZINC ION 著者 Phillips, R.K, Rayment, I. 登録日 2016-05-11 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.248 Å) 主引用文献 Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil. J.Biol.Chem., 291, 2016
5JVU	The neck-linker and alpha 7 helix of Drosophila melanogaster kinesin-1 fused to EB1 分子名称: 1,2-ETHANEDIOL, Chimera protein of Kinesin heavy chain and Microtubule-associated protein RP/EB family member 1 著者 Phillips, R.K, Rayment, I. 登録日 2016-05-11 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.948 Å) 主引用文献 Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil. J.Biol.Chem., 291, 2016
5C66	E. Coli Alkaline Phosphatase in complex with tungstate 分子名称: Alkaline phosphatase, TUNGSTATE(VI)ION, ZINC ION 著者 Peck, A, Herschlag, D. 登録日 2015-06-22 公開日 2016-06-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Tungstate as a Transition State Analog for Catalysis by Alkaline Phosphatase. J.Mol.Biol., 428, 2016
5JVR	The neck-linker of Mus musculus KIF3A fused to the alpha 7 helix of Drosophila melanogaster Kinesin-1 fused to EB1 分子名称: Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1 著者 Phillips, R.K, Rayment, I. 登録日 2016-05-11 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil. J.Biol.Chem., 291, 2016
5JVM	The neck-linker and alpha 7 helix of Mus musculus KIF3C 分子名称: Chimera protein of Kinesin-like protein KIF3C and Microtubule-associated protein RP/EB family member 1, MAGNESIUM ION 著者 Phillips, R.K, Rayment, I. 登録日 2016-05-11 公開日 2016-08-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.567 Å) 主引用文献 Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil. J.Biol.Chem., 291, 2016
5KDQ	Deoxyhemoglobin in Complex with an Aryloxyalkanoic acid 分子名称: 3-[2-chloranyl-4-(1~{H}-imidazol-2-yl)phenoxy]propanoic acid, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Ahmed, M.H, Omar, A.M, Safo, M.K. 登録日 2016-06-08 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin. Molecules, 21, 2016
5CD1	Structure of an asymmetric tetramer of human tRNA m1A58 methyltransferase in a complex with SAH and tRNA3Lys 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SODIUM ION, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A, ... 著者 Finer-Moore, J, Czudnochowski, N, O'Connell III, J.D, Wang, A.L, Stroud, R.M. 登録日 2015-07-02 公開日 2015-11-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target. J.Mol.Biol., 427, 2015
5K69	Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase 2 with carbapenem drug T224 分子名称: (2~{S},3~{R},4~{R})-4-(1~{H}-indol-3-ylsulfanyl)-3-methyl-2-[(2~{S},3~{S})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, GLYCEROL, L,D-transpeptidase 2 著者 Lamichhane, G, Ginell, S.L, Kumar, P. 登録日 2016-05-24 公開日 2016-11-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Non-classical transpeptidases yield insight into new antibacterials. Nat. Chem. Biol., 13, 2017

<83848586878889909192939495969798>