PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

---

5KNM	Human leukocyte antigen F (HLA-F) presents peptides and regulates immunity through interactions with NK-cell receptors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Leukocyte immunoglobulin-like receptor subfamily B member 1, ... 著者 Dulberger, C.L, Adams, E.J. 登録日 2016-06-28 公開日 2017-06-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors. Immunity, 46, 2017
1H80	1,3-ALPHA-1,4-BETA-D-GALACTOSE-4-SULFATE- 3,6-ANHYDRO-D-GALACTOSE-2-SULFATE 4 GALACTOHYDROLASE 分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ... 著者 Michel, G, Chantalat, L, Dideberg, O. 登録日 2001-01-22 公開日 2001-11-27 最終更新日 2018-10-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The Iota-Carrageenase of Alteromonas Fortis. A Beta-Helix Fold-Containing Enzyme for the Degradation of a Highly Polyanionic Polysaccharide J.Biol.Chem., 276, 2001
2HIS	CELLULOMONAS FIMI XYLANASE/CELLULASE DOUBLE MUTANT E127A/H205N WITH COVALENT CELLOBIOSE 分子名称: CELLULOMONAS FIMI FAMILY 10 BETA-1,4-GLYCANASE, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Notenboom, V, Birsan, C, Nitz, M, Rose, D.R, Warren, R.A.J, Wither, S.G. 登録日 1998-02-23 公開日 1998-10-14 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Insights into transition state stabilization of the beta-1,4-glycosidase Cex by covalent intermediate accumulation in active site mutants. Nat.Struct.Biol., 5, 1998
8RZB	IL-1beta in complex with covalent DEL hit 分子名称: 8-[4-methyl-3-(trifluoromethyl)phenyl]-2-[[(7S)-7-(2-morpholin-4-ylethylcarbamoyl)-4-(phenylsulfonyl)-1,4-diazepan-1-yl]carbonyl]imidazo[1,2-a]pyridine-6-carboxylic acid, Interleukin-1 beta 著者 Rondeau, J.-M, Lehmann, S. 登録日 2024-02-12 公開日 2024-05-22 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.836 Å) 主引用文献 Ligandability Assessment of IL-1 beta by Integrated Hit Identification Approaches. J.Med.Chem., 67, 2024
1GRR	CHLORAMPHENICOL PHOSPHOTRANSFERASE IN COMPLEX WITH 2-Nac-CHLORAMPHENICOL FROM STREPTOMYCES VENEZUELAE 分子名称: CHLORAMPHENICOL 3-O PHOSPHOTRANSFERASE, N-ACETYL-P-NITROPHENYLSERINOL, SULFATE ION 著者 Izard, T. 登録日 2001-12-15 公開日 2002-01-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Basis for Chloramphenicol Tolerance in Streptomyces Venezuelae by Chloramphenicol Phosphotransferase Activity Protein Sci., 10, 2001
1CB7	GLUTAMATE MUTASE FROM CLOSTRIDIUM COCHLEARIUM RECONSTITUTED WITH METHYL-COBALAMIN 分子名称: CO-METHYLCOBALAMIN, D(-)-TARTARIC ACID, PROTEIN (GLUTAMATE MUTASE) 著者 Gruber, K, Reitzer, R, Kratky, C. 登録日 1999-03-03 公開日 2000-02-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights. Structure Fold.Des., 7, 1999
1CCN	DIRECT NOE REFINEMENT OF CRAMBIN FROM 2D NMR DATA USING A SLOW-COOLING ANNEALING PROTOCOL 分子名称: CRAMBIN 著者 Bonvin, A.M.J.J, Rullmann, J.A.C, Lamerichs, R.M.J.N, Boelens, R, Kaptein, R. 登録日 1993-04-14 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Direct NOE refinement of biomolecular structures using 2D NMR data J.Biomol.NMR, 1, 1991
5KKN	Crystal structure of human ACC2 BC domain in complex with ND-646, the primary amide of ND-630 分子名称: 2-[1-[(2~{R})-2-(2-methoxyphenyl)-2-(oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-bis(oxidanylidene)thieno[2,3-d]pyrimidin-3-yl]-2-methyl-propanamide, Acetyl-CoA carboxylase 2 著者 Wang, R, Paul, D, Tong, L. 登録日 2016-06-22 公開日 2016-07-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proc.Natl.Acad.Sci.USA, 113, 2016
1CCW	STRUCTURE OF THE COENZYME B12 DEPENDENT ENZYME GLUTAMATE MUTASE FROM CLOSTRIDIUM COCHLEARIUM 分子名称: CYANOCOBALAMIN, D(-)-TARTARIC ACID, PROTEIN (GLUTAMATE MUTASE) 著者 Reitzer, R, Gruber, K, Kratky, C. 登録日 1999-03-01 公開日 2000-03-01 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Glutamate mutase from Clostridium cochlearium: the structure of a coenzyme B12-dependent enzyme provides new mechanistic insights Structure Fold.Des., 7, 1999
1GZB	PEROXIDASE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PEROXIDASE, ... 著者 Fukuyama, K, Kunishima, N, Amada, F. 登録日 1996-11-13 公開日 1997-03-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Pentacoordination of the heme iron of Arthromyces ramosus peroxidase shown by a 1.8 A resolution crystallographic study at pH 4.5. FEBS Lett., 378, 1996
1H1D	Catechol O-Methyltransferase 分子名称: 1-(3,4,DIHYDROXY-5-NITROPHENYL)-3-{4-[3-(TRIFLUOROMETHYL) PHENYL] PIPERAZIN-1-YL}PROPAN-1-ONE, CATECHOL-O-METHYLTRANSFERASE, MAGNESIUM ION, ... 著者 Archer, M, Rodrigues, M.L, Matias, P.M, Bonifacio, M.J, Learmonth, D.A, Soares-da-Silva, P, Carrondo, M.A. 登録日 2002-07-12 公開日 2003-07-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Kinetics and Crystal Structure of Catechol-O-Methyltransferase Complex with Co-Substrate and a Novel Inhibitor with Potential Therapeutic Application Mol.Pharmacol., 62, 2002
1CC4	PHE161 AND ARG166 VARIANTS OF P-HYDROXYBENZOATE HYDROXYLASE. IMPLICATIONS FOR NADPH RECOGNITION AND STRUCTURAL STABILITY. 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE) 著者 Eppink, M.H.M, Bunthof, C, Schreuder, H.A, Van Berkel, W.J.H. 登録日 1999-03-04 公開日 1999-03-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Phe161 and Arg166 variants of p-hydroxybenzoate hydroxylase. Implications for NADPH recognition and structural stability. Febs Lett., 443, 1999
1CCM	DIRECT NOE REFINEMENT OF CRAMBIN FROM 2D NMR DATA USING A SLOW-COOLING ANNEALING PROTOCOL 分子名称: CRAMBIN 著者 Bonvin, A.M.J.J, Rullmann, J.A.C, Lamerichs, R.M.J.N, Boelens, R, Kaptein, R. 登録日 1993-04-14 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 "Ensemble" iterative relaxation matrix approach: a new NMR refinement protocol applied to the solution structure of crambin. Proteins, 15, 1993
1GOH	NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE 分子名称: GALACTOSE OXIDASE, SODIUM ION 著者 Ito, N, Phillips, S.E.V, Knowles, P.F. 登録日 1993-09-30 公開日 1994-01-31 最終更新日 2023-07-26 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Nature, 350, 1991
2HIU	NMR STRUCTURE OF HUMAN INSULIN IN 20% ACETIC ACID, ZINC-FREE, 10 STRUCTURES 分子名称: INSULIN 著者 Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A. 登録日 1996-10-08 公開日 1997-04-01 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Structure of a protein in a kinetic trap. Nat.Struct.Biol., 2, 1995
1CCD	REFINED STRUCTURE OF RAT CLARA CELL 17 KDA PROTEIN AT 3.0 ANGSTROMS RESOLUTION 分子名称: CLARA CELL 17 kD PROTEIN, SULFATE ION 著者 Umland, T.C, Swaminathan, S, Furey, W, Singh, G, Pletcher, J, Sax, M. 登録日 1991-09-17 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Refined structure of rat Clara cell 17 kDa protein at 3.0 A resolution. J.Mol.Biol., 224, 1992
1KGQ	Crystal Structure of Tetrahydrodipicolinate N-Succinyltransferase in Complex with L-2-aminopimelate and Succinamide-CoA 分子名称: (2S)-2-aminoheptanedioic acid, 2,3,4,5-TETRAHYDROPYRIDINE-2-CARBOXYLATE N-SUCCINYLTRANSFERASE, SUCCINAMIDE-COA 著者 Beaman, T.W, Vogel, K.W, Drueckhammer, D.G, Blanchard, J.S, Roderick, S.L. 登録日 2001-11-28 公開日 2002-04-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Acyl group specificity at the active site of tetrahydridipicolinate N-succinyltransferase. Protein Sci., 11, 2002
1C5G	PLASMINOGEN ACTIVATOR INHIBITOR-1 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Goldsmith, E.J. 登録日 1999-12-07 公開日 1999-12-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition. Nat.Struct.Biol., 2, 1995
2C93	thrombin inhibitors 分子名称: DIMETHYL SULFOXIDE, HIRUDIN VARIANT-2, N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDE, ... 著者 Howard, N, Abell, C, Blakemore, W, Carr, R, Chessari, G, Congreve, M, Howard, S, Jhoti, H, Murray, C.W, Seavers, L.C.A, van Montfort, R.L.M. 登録日 2005-12-09 公開日 2006-07-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors J.Med.Chem., 49, 2006
2Y0E	BceC and the final step of UGDs reaction 分子名称: ACETATE ION, GLYCEROL, SULFATE ION, ... 著者 Rocha, J, Popescu, A.O, Borges, P, Mil-Homens, D, Sa-Correia, I, Fialho, A.M, Frazao, C. 登録日 2010-12-02 公開日 2011-07-27 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of Burkholderia Cepacia Udp-Glucose Dehydrogenase (Ugd) Bcec and Role of Tyr10 in Final Hydrolysis of Ugd Thioester Intermediate. J.Bacteriol., 193, 2011
3FTX	Leukotriene A4 hydrolase in complex with dihydroresveratrol and bestatin 分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, 5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol, ACETATE ION, ... 著者 Davies, D.R. 登録日 2009-01-13 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FUI	Leukotriene A4 hydrolase in complex with N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline 分子名称: IMIDAZOLE, Leukotriene A-4 hydrolase, N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline, ... 著者 Davies, D.R. 登録日 2009-01-14 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
2C8Z	thrombin inhibitors 分子名称: 1-(3-CHLOROPHENYL)METHANAMINE, DIMETHYL SULFOXIDE, HIRUDIN VARIANT-2, ... 著者 Howard, N, Abell, C, Blakemore, W, Carr, R, Chessari, G, Congreve, M, Howard, S, Jhoti, H, Murray, C.W, Seavers, L.C.A, van Montfort, R.L.M. 登録日 2005-12-08 公開日 2006-07-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors J.Med.Chem., 49, 2006
3FU0	Leukotriene A4 hydrolase in complex with fragment 4-(4-fluorobenzoyl)pyridine 分子名称: (4-fluorophenyl)(pyridin-4-yl)methanone, ACETATE ION, IMIDAZOLE, ... 著者 Davies, D.R. 登録日 2009-01-13 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FUH	Leukotriene A4 hydrolase in complex with fragment 5-hydroxyindole and bestatin 分子名称: 1H-indol-5-ol, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, IMIDAZOLE, ... 著者 Davies, D.R. 登録日 2009-01-14 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009

<873874875876877878879880881882883884885886887888>