PDB: 2824 件ウェブページステータス検索Chemie searchBIRD

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5KY8	mouse POFUT1 in complex with O-glucosylated mouse Notch1 EGF12 mutant (D464G) and GDP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP-fucose protein O-fucosyltransferase 1, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Li, Z, Rini, J.M. 登録日 2016-07-21 公開日 2017-05-17 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1. Nat. Chem. Biol., 13, 2017
5L0R	human POGLUT1 in complex with Notch1 EGF12 and UDP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Li, Z, Rini, J.M. 登録日 2016-07-28 公開日 2017-08-09 最終更新日 2021-03-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1). Nat Commun, 8, 2017
6CGX	Backbone cyclised conotoxin Vc1.1 mutant - D11A, E14A 分子名称: Alpha-conotoxin Vc1A 著者 Clark, R.J. 登録日 2018-02-21 公開日 2018-05-23 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structure-Activity Studies Reveal the Molecular Basis for GABAB-Receptor Mediated Inhibition of High Voltage-Activated Calcium Channels by alpha-Conotoxin Vc1.1. ACS Chem. Biol., 13, 2018
1ZWH	Yeast Hsp82 in complex with the novel Hsp90 inhibitor Radester amine 分子名称: 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE, ATP-dependent molecular chaperone HSP82 著者 Immormino, R.M, Blagg, B.S, Gewirth, D.T. 登録日 2005-06-03 公開日 2006-06-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Inhibitory Ligands Adopt Different Conformations When Bound to Hsp90 or GRP94: Implications for Paralog-specific Drug Design To be Published
2FYP	GRP94 in complex with the novel HSP90 Inhibitor Radester amine 分子名称: 2-(3-AMINO-2,5,6-TRIMETHOXYPHENYL)ETHYL 5-CHLORO-2,4-DIHYDROXYBENZOATE, Endoplasmin, PENTAETHYLENE GLYCOL, ... 著者 Immormino, R.M, Gewirth, D.T. 登録日 2006-02-08 公開日 2007-02-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Inhibittory Ligands Adopt Different Conformations When Bound to Hsp90 or GRP94: Implications for Paralog-specific Drug Design To be Published
7O3C	Murine supercomplex CIII2CIV in the mature unlocked conformation 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... 著者 Vercellino, I, Sazanov, L.A. 登録日 2021-04-01 公開日 2021-10-13 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV. Nature, 598, 2021
7O3E	Murine supercomplex CIII2CIV in the intermediate locked conformation 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... 著者 Vercellino, I, Sazanov, L.A. 登録日 2021-04-01 公開日 2021-10-13 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV. Nature, 598, 2021
7O37	Murine supercomplex CIII2CIV in the assembled locked conformation 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... 著者 Vercellino, I, Sazanov, L.A. 登録日 2021-04-01 公開日 2021-10-13 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV. Nature, 598, 2021
5UB5	human POGLUT1 in complex with human Notch1 EGF12 S458T mutant and UDP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus notch homolog protein 1, ... 著者 Li, Z, Rini, J.M. 登録日 2016-12-20 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.089 Å) 主引用文献 Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1). Nat Commun, 8, 2017
4QHR	The structure of alanine racemase from Acinetobacter baumannii 分子名称: Alanine racemase 著者 Davis, E, Scaletti-Hutchinson, E, Nakatani, Y, Krause, K.L. 登録日 2014-05-29 公開日 2015-05-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structure of alanine racemase from Acinetobacter baumannii ACTA CRYSTALLOGR.,SECT.F, 70, 2014
2YGE	E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin 分子名称: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN, GLYCEROL 著者 Roe, M, Prodromou, C, Pearl, L.H. 登録日 2011-04-14 公開日 2011-11-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.956 Å) 主引用文献 Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise by Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25, 2011
2YGF	L89V, L93I and V136M Mutant of N-Term HSP90 complexed with Geldanamycin 分子名称: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN, GLYCEROL 著者 Roe, M, Prodromou, C, Pearl, L.H. 登録日 2011-04-14 公開日 2011-11-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise by Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25, 2011
2YGA	E88G-N92L Mutant of N-Term HSP90 complexed with Geldanamycin 分子名称: ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, GELDANAMYCIN 著者 Roe, S.M, Prodromou, C, Pearl, L.H. 登録日 2011-04-12 公開日 2011-11-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Features of the Streptomyces Hygroscopicus Htpg Reveal How Partial Geldanamycin Resistance Can Arise with Mutation to the ATP Binding Pocket of a Eukaryotic Hsp90. Faseb J., 25, 2011
3A7Q	Structural basis for specific recognition of reelin by its receptors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Yasui, N, Nogi, T, Takagi, J. 登録日 2009-10-01 公開日 2010-03-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for Specific Recognition of Reelin by Its Receptors Structure, 18, 2010
2ZCI	Structure of a GTP-dependent bacterial PEP-carboxykinase from Corynebacterium glutamicum 分子名称: Phosphoenolpyruvate carboxykinase [GTP] 著者 Aich, S, Prasad, L, Delbaere, L.T.J. 登録日 2007-11-09 公開日 2008-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of a GTP-dependent bacterial PEP-carboxykinase from Corynebacterium glutamicum. Int.J.Biochem.Cell Biol., 40, 2008
7ZZ6	Cryo-EM structure of "CT-CT dimer" of Lactococcus lactis pyruvate carboxylase with acetyl-CoA 分子名称: MAGNESIUM ION, MANGANESE (II) ION, PYRUVIC ACID, ... 著者 Lopez-Alonso, J.P, Lazaro, M, Gil, D, Choi, P.H, Tong, L, Valle, M. 登録日 2022-05-25 公開日 2022-12-28 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.15 Å) 主引用文献 CryoEM structural exploration of catalytically active enzyme pyruvate carboxylase. Nat Commun, 13, 2022
8A1G	Structure of the SNX1-SNX5 complex 分子名称: N-PROPANOL, Sorting nexin-1, Sorting nexin-5 著者 Lopez-Robles, C, Scaramuzza, S, Astorga-Simon, E.N, Banos-Mateos, S, Vidaurrazaga, A, Rojas, A.L, Castano, D, Hierro, A. 登録日 2022-06-01 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Architecture of the ESCPE-1 membrane coat. Nat.Struct.Mol.Biol., 30, 2023
2C5G	Torpedo californica acetylcholinesterase in complex with 20mM thiocholine 分子名称: 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... 著者 Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M. 登録日 2005-10-27 公開日 2006-06-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase. Embo J., 25, 2006
2C4H	Torpedo californica acetylcholinesterase in complex with 500mM acetylthiocholine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ACETYL GROUP, ... 著者 Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M. 登録日 2005-10-19 公開日 2006-06-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural insights into substrate traffic and inhibition in acetylcholinesterase. EMBO J., 25, 2006
2C5F	Torpedo californica acetylcholinesterase in complex with a non hydrolysable substrate analogue, 4-oxo-N,N,N-trimethylpentanaminium 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, ACETYLCHOLINESTERASE, ... 著者 Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M. 登録日 2005-10-27 公開日 2006-06-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase. Embo J., 25, 2006
2C58	Torpedo californica acetylcholinesterase in complex with 20mM acetylthiocholine 分子名称: 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... 著者 Colletier, J.P, Fournier, D, Greenblatt, H.M, Sussman, J.L, Zaccai, G, Silman, I, Weik, M. 登録日 2005-10-26 公開日 2006-06-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Insights Into Substrate Traffic and Inhibition in Acetylcholinesterase. Embo J., 25, 2006
2C0Q	non-aged form of mouse acetylcholinesterase inhibited by tabun 分子名称: ACETYLCHOLINESTERASE, HEXAETHYLENE GLYCOL, R-ETHYL N,N-DIMETHYLPHOSPHONAMIDATE 著者 Ekstrom, F, Akfur, C, Tunemalm, A.-K, Lundberg, S. 登録日 2005-09-07 公開日 2006-01-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Changes of Phenylalanine 338 and Histidine 447 Revealed by the Crystal Structures of Tabun-Inhibited Murine Acetylcholinesterase. Biochemistry, 45, 2006
2C0P	Aged form of mouse acetylcholinesterase inhibited by tabun 分子名称: ACETYLCHOLINESTERASE, ETHYL HYDROGEN PHOSPHONATE 著者 Ekstrom, F, Akfur, C, Tunemalm, A.-K, Lundberg, S. 登録日 2005-09-07 公開日 2006-01-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Changes of Phenylalanine 338 and Histidine 447 Revealed by the Crystal Structures of Tabun-Inhibited Murine Acetylcholinesterase. Biochemistry, 45, 2006
1XDT	COMPLEX OF DIPHTHERIA TOXIN AND HEPARIN-BINDING EPIDERMAL GROWTH FACTOR 分子名称: DIPHTHERIA TOXIN, HEPARIN-BINDING EPIDERMAL GROWTH FACTOR 著者 Louie, G.V, Yang, W, Bowman, M.E, Choe, S. 登録日 1997-11-18 公開日 1998-02-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor. Mol.Cell, 1, 1997
2E26	Crystal structure of two repeat fragment of reelin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Yasui, N, Nogi, T, Kitao, T, Takagi, J. 登録日 2006-11-08 公開日 2007-05-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors. Proc.Natl.Acad.Sci.Usa, 104, 2007

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