4ASG
| The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90 | 分子名称: | ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, NICKEL (II) ION, [(3R,5S,6R,7R,11S,12Z,14E)-5,11,21-trimethoxy-3,7,9,15-tetramethyl-6-oxidanyl-16,20,22-tris(oxidanylidene)-19-phenyl-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate | 著者 | Roe, S.M, Prodromou, C. | 登録日 | 2012-05-01 | 公開日 | 2013-04-03 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Synthesis of 19-Substituted Geldanamycins with Altered Conformations and Their Binding to Heat Shock Protein Hsp90. Nat.Chem., 5, 2013
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4ASA
| The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90 | 分子名称: | ATP-DEPENDENT MOLECULAR CHAPERONE HSP82, CHLORIDE ION, [(3R,5S,6R,7R,12E)-5,11-dimethoxy-3,7,9,15,19-pentamethyl-6-oxidanyl-16,20,22-tris(oxidanylidene)-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate | 著者 | Roe, S.M, Prodromou, C. | 登録日 | 2012-04-30 | 公開日 | 2013-04-03 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Synthesis of 19-Substituted Geldanamycins with Altered Conformations and Their Binding to Heat Shock Protein Hsp90. Nat.Chem., 5, 2013
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4ASB
| The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90 | 分子名称: | (4E,6E,8S,9R,10E,12R,13R,14S,16R)-19-{[2-(dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16,21-pentamethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate, ATP-DEPENDENT MOLECULAR CHAPERONE HSP82 | 著者 | Roe, S.M, Prodromou, C. | 登録日 | 2012-04-30 | 公開日 | 2013-04-03 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90. Nat Chem, 5, 2013
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4DA8
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 8-bromoguanosine | 分子名称: | 8-bromoguanosine, Purine nucleoside phosphorylase deoD-type | 著者 | Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-12 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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1E66
| STRUCTURE OF ACETYLCHOLINESTERASE COMPLEXED WITH (-)-HUPRINE X AT 2.1A RESOLUTION | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-CHLORO-9-ETHYL-6,7,8,9,10,11-HEXAHYDRO-7,11-METHANOCYCLOOCTA[B]QUINOLIN-12-AMINE, ACETYLCHOLINESTERASE | 著者 | Dvir, H, Harel, M, Silman, I, Sussman, J.L. | 登録日 | 2000-08-08 | 公開日 | 2001-08-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | 3D Structure of Torpedo Californica Acetylcholinesterase Complexed with Huprine X at 2. 1 A Resolution: Kinetic and Molecular Dynamic Correlates. Biochemistry, 41, 2002
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1EA5
| NATIVE ACETYLCHOLINESTERASE (E.C. 3.1.1.7) FROM TORPEDO CALIFORNICA at 1.8A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE | 著者 | Harel, M, Weik, M, Silman, I, Sussman, J.L. | 登録日 | 2000-11-06 | 公開日 | 2000-11-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-Ray Structures of Torpedo Californica Acetylcholinesterase Complexed with (+)-Huperzine a and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement Biochemistry, 41, 2002
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4D8Y
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group P212121 at pH 5.6 | 分子名称: | GLYCEROL, Purine nucleoside phosphorylase deoD-type, SULFATE ION | 著者 | Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. | 登録日 | 2012-01-11 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4D8X
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group P6322 at pH 4.6 | 分子名称: | Purine nucleoside phosphorylase deoD-type | 著者 | Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. | 登録日 | 2012-01-11 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4D8V
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis at pH 4.2 | 分子名称: | ADENINE, Purine nucleoside phosphorylase deoD-type, SULFATE ION | 著者 | Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. | 登録日 | 2012-01-11 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4D98
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in space group H32 at pH 7.5 | 分子名称: | CHLORIDE ION, GLYCEROL, Purine nucleoside phosphorylase deoD-type, ... | 著者 | Santos, C.R, Meza, A.N, Martins, N.H, Giuseppe, P.O, Murakami, M.T. | 登録日 | 2012-01-11 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4D9H
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with adenosine | 分子名称: | ADENOSINE, Purine nucleoside phosphorylase deoD-type | 著者 | Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-11 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4DA0
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2'-deoxyguanosine | 分子名称: | 2'-DEOXY-GUANOSINE, CHLORIDE ION, Purine nucleoside phosphorylase deoD-type | 著者 | Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-12 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4DAB
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with hypoxanthine | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-12 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4DAE
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 6-chloroguanosine | 分子名称: | 6-chloro-9-(beta-D-ribofuranosyl)-9H-purin-2-amine, ACETATE ION, CHLORIDE ION, ... | 著者 | Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-12 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4DAN
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2-fluoroadenosine | 分子名称: | 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Purine nucleoside phosphorylase deoD-type | 著者 | Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-13 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4DAO
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with adenine | 分子名称: | ADENINE, GLYCEROL, Purine nucleoside phosphorylase deoD-type | 著者 | Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-13 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4DAR
| Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with tubercidin | 分子名称: | '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, Purine nucleoside phosphorylase deoD-type | 著者 | Giuseppe, P.O, Martins, N.H, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-13 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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4MP4
| Crystal structure of a glutathione transferase family member from Acinetobacter baumannii, Target EFI-501785, apo structure | 分子名称: | Glutathione S-transferase, SULFATE ION | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Armstrong, R.N, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-09-12 | 公開日 | 2013-10-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | 主引用文献 | Crystal structure of a glutathione transferase family member from Acinetobacter baumannii, Target EFI-501785, apo structure To be Published
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1TFS
| NMR AND RESTRAINED MOLECULAR DYNAMICS STUDY OF THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF TOXIN FS2, A SPECIFIC BLOCKER OF THE L-TYPE CALCIUM CHANNEL, ISOLATED FROM BLACK MAMBA VENOM | 分子名称: | TOXIN FS2 | 著者 | Albrand, J.-P, Blackledge, M.J, Pascaud, F, Hollecker, M, Marion, D. | 登録日 | 1995-01-26 | 公開日 | 1995-03-31 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR and restrained molecular dynamics study of the three-dimensional solution structure of toxin FS2, a specific blocker of the L-type calcium channel, isolated from black mamba venom. Biochemistry, 34, 1995
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1EZR
| CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR | 分子名称: | CALCIUM ION, NUCLEOSIDE HYDROLASE | 著者 | Shi, W, Schramm, V.L, Almo, S.C. | 登録日 | 2000-05-11 | 公開日 | 2000-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure. J.Biol.Chem., 274, 1999
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5KY9
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8CHY
| Crystal structure of an 8-repeat consensus TPR superhelix with Zinc. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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8CH0
| Crystal structure of an 8-repeat consensus TPR superhelix with Gadolinium. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Consensus tetratricopeptide repeat protein, ... | 著者 | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | 登録日 | 2023-02-06 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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8CIG
| Crystal structure of an 8-repeat consensus TPR superhelix in tris Buffer with Calcium. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | 著者 | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | 登録日 | 2023-02-09 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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5KY0
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