PDB: 47902 件ウェブページステータス検索Chemie searchBIRD

---

6P1I	Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA Primer 20-mer, DNA template 27-mer, ... 著者 Bertoletti, N, Anderson, K.S. 登録日 2019-05-19 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.74 Å) 主引用文献 Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine. Protein Sci., 28, 2019
5OF1	The structural versatility of TasA in B. subtilis biofilm formation 分子名称: 2-HYDROXYBENZOIC ACID, Spore coat-associated protein N, ethane-1,2-diol 著者 Roske, Y, Diehl, A, Ball, L, Chowdhury, A, Hiller, M, Moliere, N, Kramer, R, Nagaraj, M, Stoeppler, D, Worth, C.L, Schlegel, B, Leidert, M, Cremer, N, Eisenmenger, F, Lopez, D, Schmieder, P, Heinemann, U, Turgay, K, Akbey, U, Oschkinat, H. 登録日 2017-07-10 公開日 2018-03-21 最終更新日 2018-04-11 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Structural changes of TasA in biofilm formation ofBacillus subtilis. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5O3M	Crystal structure of apo Klebsiella pneumoniae 3,4-dihydroxybenzoic acid decarboxylase (AroY) 分子名称: Protocatechuate decarboxylase, pentane-1,5-diol 著者 Marshall, S.A, Leys, D. 登録日 2017-05-24 公開日 2017-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Regioselective para-Carboxylation of Catechols with a Prenylated Flavin Dependent Decarboxylase. Angew. Chem. Int. Ed. Engl., 56, 2017
6P26	Escherichia coli tRNA synthetase in complex with compound 1 分子名称: N-benzyl-2-(cyclohex-1-en-1-yl)ethan-1-amine, Phenylalanine--tRNA ligase alpha subunit, Phenylalanine--tRNA ligase beta subunit 著者 Kahne, D, Baidin, V, Owens, T.W. 登録日 2019-05-21 公開日 2020-11-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through Highly Selective Binding to Phenylalanyl-tRNA Synthetase. J.Am.Chem.Soc., 143, 2021
6P2S	Structure of a nested set of N-terminally extended MHC I-peptides provide novel insights into antigen processing and presentation 分子名称: Beta-2-microglobulin, MHC I-peptide, MHC class I antigen 著者 Li, L, Batliwala, M, Bouvier, M. 登録日 2019-05-22 公開日 2019-10-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation. J.Biol.Chem., 294, 2019
6PFY	Membrane Protein Megahertz Crystallography at the European XFEL, Photosystem I at synchrotron to 2.9 A 分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... 著者 Fromme, R. 登録日 2019-06-23 公開日 2019-11-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Membrane protein megahertz crystallography at the European XFEL. Nat Commun, 10, 2019
6P3E	Mobile loops and electrostatic interactions maintain the flexible lambda tail tube 分子名称: Tail tube protein 著者 Campbell, P, Duda, R.L, Nassur, J, Hendrix, R.W, Conway, J.F, Huet, A. 登録日 2019-05-23 公開日 2019-11-27 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (5.4 Å) 主引用文献 Mobile Loops and Electrostatic Interactions Maintain the Flexible Tail Tube of Bacteriophage Lambda. J.Mol.Biol., 432, 2020
5OFN	Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus. 分子名称: DNA primase large subunit PriL,PriL-X fusion protein, DNA primase small subunit PriS, ZINC ION 著者 Pellegrini, L, Holzer, S. 登録日 2017-07-11 公開日 2017-11-29 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.005 Å) 主引用文献 Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster. Nat Commun, 8, 2017
6POD	ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 2 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... 著者 Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. 登録日 2019-07-03 公開日 2020-03-11 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.05 Å) 主引用文献 Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
6P5T	Surface-layer (S-layer) RsaA protein from Caulobacter crescentus bound to strontium and iodide 分子名称: IODIDE ION, S-layer protein, STRONTIUM ION 著者 Chan, A.C, Herrmann, J, Smit, J, Wakatsuki, S, Murphy, M.E. 登録日 2019-05-30 公開日 2020-01-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly. Proc.Natl.Acad.Sci.USA, 117, 2020
6PLI	Crystal Structure of EcDsbA in a complex with purified oxadiazole 11 分子名称: 2-[4-(4-cyano-3-methylphenoxy)phenyl]-N-methyl-N-[2-(5-methyl-1,2,4-oxadiazol-3-yl)ethyl]acetamide, COPPER (II) ION, Thiol:disulfide interchange protein DsbA 著者 Ilyichova, O.V, Bentley, M, Doak, B, Scanlon, M.J. 登録日 2019-07-01 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiL X ). J.Med.Chem., 63, 2020
5OGP	Metalacarborane inhibitors of Carbonic Anhydrase IX 分子名称: Carbonic anhydrase 2, ZINC ION, cobaltcarborane 著者 Brynda, J, Rezacova, P, Pospisilova, K, Kugler, M, Gruner, B, Sicha, V. 登録日 2017-07-13 公開日 2018-08-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX. J.Med.Chem., 2019
6PNA	Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 7-(4-(2-Aminoethyl)phenyl)-4-methylquinolin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[4-(2-aminoethyl)phenyl]-4-methylquinolin-2-amine, GLYCEROL, ... 著者 Li, H, Poulos, T.L. 登録日 2019-07-02 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate. J.Med.Chem., 63, 2020
6PNY	X-ray Structure of Flpp3 分子名称: Flpp3 著者 Zook, J.D, Shekhar, M, Hansen, D.T, Conrad, C, Grant, T.D, Gupta, C, White, T, Barty, A, Basu, S, Zhao, Y, Zatsepin, N.A, Ishchenko, A, Batyuk, A, Gati, C, Li, C, Galli, L, Coe, J, Hunter, M, Liang, M, Weierstall, U, Nelson, G, James, D, Stauch, B, Craciunescu, F, Thifault, D, Liu, W, Cherezov, V, Singharoy, A, Fromme, P. 登録日 2019-07-03 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. Structure, 28, 2020
6P9S	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 7 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6P0X	Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACRYLIC ACID, GLYCEROL, ... 著者 Xu, C, Boniecki, M, Cygler, M. 登録日 2019-05-17 公開日 2019-06-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2 To Be Published
5O8E	Mutant of class II CPD photolyase from Methanosarcina mazei 分子名称: Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Ignatz, E, Geisselbrecht, Y, Essen, L.-O. 登録日 2017-06-13 公開日 2017-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Nicotinamide Adenine Dinucleotides Arrest Photoreduction of Class II DNA Photolyases in FADH ̇ State. Photochem. Photobiol., 94, 2018
6P1X	Structure of HIV-1 Reverse Transcriptase (RT) in complex with dsDNA and L-ddCTP 分子名称: DNA Primer 20-mer, DNA template 27-mer, MAGNESIUM ION, ... 著者 Bertoletti, N, Anderson, K.S. 登録日 2019-05-20 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.553 Å) 主引用文献 Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine. Protein Sci., 28, 2019
6P2H	Structural basis for 2'-deoxyguanosine recognition by the 2'-dG-II class of riboswitches 分子名称: 2'-DEOXY-GUANOSINE, COBALT HEXAMMINE(III), MAGNESIUM ION, ... 著者 Matyjasik, M.M, Batey, R.T. 登録日 2019-05-21 公開日 2019-10-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.803 Å) 主引用文献 Structural basis for 2'-deoxyguanosine recognition by the 2'-dG-II class of riboswitches. Nucleic Acids Res., 47, 2019
5OKI	Crystal structure of the Ctf18-1-8 module from Ctf18-RFC in complex with a 63 kDa fragment of DNA Polymerase epsilon 分子名称: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ... 著者 Grabarczyk, D.B, Kisker, C. 登録日 2017-07-25 公開日 2017-12-20 最終更新日 2018-01-10 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structural Basis for the Recruitment of Ctf18-RFC to the Replisome. Structure, 26, 2018
7WIM	Crystal structure of Arabidopsis thaliana FKBP43 N-terminal domain 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP43 著者 Singh, A.K, Saharan, K, Baral, S, Vasudevan, D. 登録日 2022-01-03 公開日 2022-09-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 The plant nucleoplasmin AtFKBP43 needs its extended arms for histone interaction. Biochim Biophys Acta Gene Regul Mech, 1865, 2022
7WCV	Co-crystal structure of FTO bound to 6e 分子名称: 2-OXOGLUTARIC ACID, 2-[[2,6-bis(chloranyl)-4-pyridin-4-yl-phenyl]amino]benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ... 著者 Yang, C.-G, Gan, J.H. 登録日 2021-12-20 公開日 2022-07-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors. J.Med.Chem., 65, 2022
6P4X	Crystal Structure of the S. cerevisiae glucokinase, Glk1 分子名称: Glucokinase-1, PHOSPHATE ION 著者 Stoddard, P.R, Garner, E.C, Murray, A.W. 登録日 2019-05-28 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.59 Å) 主引用文献 Polymerization in the actin ATPase clan regulates hexokinase activity in yeast. Science, 367, 2020
5NXR	Trimeric structure of Omp-Pst1, the major porin from Providencia stuartii 分子名称: CALCIUM ION, CHLORIDE ION, LAURYL DIMETHYLAMINE-N-OXIDE, ... 著者 Colletier, J.P, Nasrallah, C. 登録日 2017-05-10 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Porin self-association enables cell-to-cell contact in Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6P6Z	HCV NS3/4A protease domain of genotype 4a with an extended linker in complex with glecaprevir 分子名称: (3aR,7S,10S,12R,21E,24aR)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclop ropyl]-20,20-difluoro-5,8-dioxo-2,3,3a,5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12-methanocyclopenta[18,19][1,10,17, 3,6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide, Non-structural protein 4A,Serine protease NS3, ... 著者 Timm, J, Schiffer, C.A. 登録日 2019-06-04 公開日 2020-06-10 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.294 Å) 主引用文献 Molecular mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir and characterization of genotype-specific structural differences To Be Published

<807808809810811812813814815816817818819820821822>