PDB: 35863 件ウェブページステータス検索Chemie searchBIRD

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2Z4W	S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-749 分子名称: Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, [(6E,11E)-2,6,12,16-tetramethylheptadeca-2,6,11,15-tetraene-9,9-diyl]bis(phosphonic acid) 著者 Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J. 登録日 2007-06-26 公開日 2008-07-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation J.Med.Chem., 51, 2008
5M0P	Crystal structure of cytochrome P450 OleT F79A in complex with arachidonic acid 分子名称: PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, Terminal olefin-forming fatty acid decarboxylase, ... 著者 Tee, K.L, Munro, A, Matthews, S, Leys, D, Levy, C. 登録日 2016-10-05 公開日 2017-01-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE. J. Biol. Chem., 292, 2017
5U3A	Ultra High Resolution Crystal Structure of Human Pancreatic Alpha Amylase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Caner, S, Brayer, G.D. 登録日 2016-12-01 公開日 2017-12-06 最終更新日 2022-04-27 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Folding Then Binding vs Folding Through Binding in Macrocyclic Peptide Inhibitors of Human Pancreatic alpha-Amylase. Acs Chem.Biol., 14, 2019
5LI6	Crystal structure of Mycobacterium tuberculosis CYP126A1 in complex with N-isopropyl-N-((3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl)methyl)-2-(4-nitrophenyl)acetamide 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative cytochrome P450 126, ~{N}-[[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl]-2-(4-nitrophenyl)-~{N}-propan-2-yl-ethanamide 著者 Levy, C, Munro, A.W, Leys, D. 登録日 2016-07-14 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1. J. Biol. Chem., 292, 2017
8IWD	Aspergillus niger Rha-2 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Li, L.J, Li, L, Wang, M.H, Jiang, Z.D, Zhu, Y.B, Jin, T.C, Ni, H. 登録日 2023-03-29 公開日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Crystal structure and catalytic function of alpha-L-rhamnosidase from Aspergillus niger To Be Published
5M0X	Structure of apo structure of GH36 alpha-galactosidase from Thermotoga maritima 分子名称: Alpha-galactosidase, MAGNESIUM ION, SULFATE ION 著者 Pengelly, R, Gloster, T. 登録日 2016-10-06 公開日 2016-11-09 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Snapshots for Mechanism-Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars. Angew.Chem.Int.Ed.Engl., 55, 2016
6GE3	X-ray structure of TEAD4 (wildtype) complexed with YAP (wildtype): The role of residual flexibility and water molecules in the adaptation of a bound intrinsically disordered protein to mutations at a binding interface 分子名称: GLYCEROL, MYRISTIC ACID, Transcriptional coactivator YAP1, ... 著者 Kallen, J. 登録日 2018-04-25 公開日 2018-09-19 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface. Protein Sci., 27, 2018
3NYJ	Crystal Structure Analysis of APP E2 domain 分子名称: Amyloid beta A4 protein, OSMIUM ION 著者 Ha, Y, Hu, J, Lee, S, Liu, X. 登録日 2010-07-15 公開日 2011-06-01 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization. Biochemistry, 50, 2011
8J0N	cryo-EM structure of human EMC 分子名称: ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... 著者 Li, M, Zhang, C, Wu, J, Lei, M. 登録日 2023-04-11 公開日 2024-04-03 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Structural insights into human EMC and its interaction with VDAC. Aging (Albany NY), 16, 2024
5LIN	Lysozyme, collected at rotation 1 degree per second 分子名称: CHLORIDE ION, Lysozyme C 著者 Casanas, A, Finke, A, Wang, M. 登録日 2016-07-15 公開日 2016-08-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.496 Å) 主引用文献 EIGER detector: application in macromolecular crystallography. Acta Crystallogr D Struct Biol, 72, 2016
1F1W	SRC SH2 THREF1TRP MUTANT COMPLEXED WITH THE PHOSPHOPEPTIDE S(PTR)VNVQN 分子名称: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, S(PTR)VNVQN PHOSPHOPEPTIDE 著者 Kimber, M.S, Nachman, J, Cunningham, A.M, Gish, G.D, Pawson, T, Pai, E.F. 登録日 2000-05-20 公開日 2000-07-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for specificity switching of the Src SH2 domain. Mol.Cell, 5, 2000
8D8P	Crystal structure of a novel fatty acid decarboxylase from Rothia nasimurium 分子名称: Decarboxylase, PALMITIC ACID, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Vieira, P.S, Murakami, M.T, Zanphorlin, L.M. 登録日 2022-06-08 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystal structure of a novel fatty acid decarboxylase from Rothia nasimurium Proc.Natl.Acad.Sci.USA, 2023
8DHL	Tannerella forsythia beta-glucuronidase (L2) 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Glycosyl hydrolase family 2, ... 著者 Lietzan, A.D, Redinbo, M.R. 登録日 2022-06-27 公開日 2023-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Microbial beta-glucuronidases drive human periodontal disease etiology. Sci Adv, 9, 2023
6G3W	Crystal structure of the BIR3 - SERK2 complex from Arabidopsis thaliana. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... 著者 Hothorn, M, Hohmann, U. 登録日 2018-03-26 公開日 2018-04-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The SERK3 elongated allele defines a role for BIR ectodomains in brassinosteroid signalling. Nat Plants, 4, 2018
1F5F	CRYSTAL STRUCTURE OF THE N-TERMINAL G-DOMAIN OF SHBG IN COMPLEX WITH ZINC 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, CALCIUM ION, ISOPROPYL ALCOHOL, ... 著者 Avvakumov, V.A, Muller, Y.A, Hammond, G.L. 登録日 2000-06-14 公開日 2000-09-06 最終更新日 2018-04-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site. J.Biol.Chem., 275, 2000
5LK2	Structure of hantavirus envelope glycoprotein Gc in postfusion conformation in presence of 300 mM KCL 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein, POTASSIUM ION, ... 著者 Guardado-Calvo, P, Rey, F.A. 登録日 2016-07-20 公開日 2016-09-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc. Plos Pathog., 12, 2016
7KWA	Structure of DCN1 bound to N-((4S,5S)-3-(aminomethyl)-7-ethyl-4-(4-fluorophenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-(trifluoromethyl)benzamide 分子名称: Endolysin,DCN1-like protein 1, N-[(4S,5S)-3-(aminomethyl)-7-ethyl-4-(4-fluorophenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-(trifluoromethyl)benzamide 著者 Kim, H.S, Hammill, J.T, Schulman, B.A, Guy, R.K, Scott, D.C. 登録日 2020-11-30 公開日 2021-07-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.572 Å) 主引用文献 Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M. J.Med.Chem., 64, 2021
8CZZ	Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with Temsavir, 8ANC195, and 10-1074 分子名称: 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chen, Y, Pozharski, E, Tolbert, W, Pazgier, M. 登録日 2022-05-25 公開日 2023-05-31 最終更新日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.14 Å) 主引用文献 Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
5U8W	Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa bound to NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, DIMETHYL SULFOXIDE, Dihydrolipoyl dehydrogenase, ... 著者 Glasser, N.R, Wang, B.X, Hoy, J.A, Newman, D.K. 登録日 2016-12-15 公開日 2017-02-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 The Pyruvate and alpha-Ketoglutarate Dehydrogenase Complexes of Pseudomonas aeruginosa Catalyze Pyocyanin and Phenazine-1-carboxylic Acid Reduction via the Subunit Dihydrolipoamide Dehydrogenase. J. Biol. Chem., 292, 2017
7L1Y	Unlocking the structural features for the exo-xylobiosidase activity of an unusual GH11 member identified in a compost-derived consortium-xylobiose complex 分子名称: 1,2-ETHANEDIOL, Exo-B-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose 著者 Kadowaki, M.A.S, Polikarpov, I, Briganti, L, Evangelista, D.E. 登録日 2020-12-15 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Unlocking the structural features for the xylobiohydrolase activity of an unusual GH11 member identified in a compost-derived consortium. Biotechnol.Bioeng., 118, 2021
6GEE	TEAD4 (216-434);E263A COMPLEXED WITH YAP PEPTIDE (60-100); S94A AND MYRISTOATE (COVALENTLY BOUND) AT 1.96A (P41212 CRYSTAL FORM); MYRISTOYLATION WAS DONE BY ADDING MYR-COA 分子名称: MYRISTIC ACID, Transcriptional coactivator YAP1, Transcriptional enhancer factor TEF-3 著者 Kallen, J. 登録日 2018-04-26 公開日 2018-09-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface. Protein Sci., 27, 2018
8D5T	Crystal structure of hen egg white lysozyme at 100 Kelvin (Duplicate) 分子名称: CHLORIDE ION, GLYCEROL, Lysozyme C, ... 著者 Ribeiro, F.S, Lima, L.M.T.R. 登録日 2022-06-06 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Linking B-factor and temperature-induced conformational transition. Biophys.Chem., 298, 2023
8IUS	Crystal structure of Manganese-free N(omega)-hydroxy-L-arginine hydrolase with reduced Cys86 分子名称: MAGNESIUM ION, MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase 著者 Oda, K, Matoba, Y. 登録日 2023-03-25 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Copper inactivates DcsB by oxidation of the Cys86 to cysteine sulfinic aicd To Be Published
8D69	Crystal structure of hen egg white lysozyme at 175 Kelvin 分子名称: CHLORIDE ION, GLYCEROL, Lysozyme C, ... 著者 Ribeiro, F.S, Lima, L.M.T.R. 登録日 2022-06-06 公開日 2023-05-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Linking B-factor and temperature-induced conformational transition. Biophys.Chem., 298, 2023
8IUU	Crystal structure of Manganese-rebound N(omega)-hydroxy-L-arginine hydrolase with oxidized Cys86 分子名称: MAGNESIUM ION, MANGANESE (II) ION, N(omega)-hydroxy-L-arginine amidinohydrolase 著者 Oda, K, Matoba, Y. 登録日 2023-03-25 公開日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.26 Å) 主引用文献 Copper inactivates DcsB by oxidation of the Cys86 to cysteine sulfinic aicd To Be Published

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