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7Y5B
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Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Saw, W.-G, Wong, C.F, Grueber, G.
登録日2022-06-16
公開日2022-11-23
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
7Y5D
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BU of 7y5d by Molmil
Cryo-EM structure of F-ATP synthase from Mycolicibacterium smegmatis (rotational state 3) (backbone)
分子名称: ATP synthase epsilon chain, ATP synthase gamma chain, ATP synthase subunit a, ...
著者Saw, W.-G, Wong, C.F, Grueber, G.
登録日2022-06-16
公開日2022-11-23
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors.
Antimicrob.Agents Chemother., 66, 2022
8H9Q
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BU of 8h9q by Molmil
Human ATP synthase state 3b subregion 3
分子名称: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ...
著者Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-10-25
公開日2023-05-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structure of the human ATP synthase.
Mol.Cell, 83, 2023
8H9U
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BU of 8h9u by Molmil
Human ATP synthase state 3a (combined)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ...
著者Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-10-25
公開日2023-05-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Structure of the human ATP synthase.
Mol.Cell, 83, 2023
8H9V
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BU of 8h9v by Molmil
Human ATP synthase state 3b (combined)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ...
著者Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-10-25
公開日2023-05-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Structure of the human ATP synthase.
Mol.Cell, 83, 2023
8H9M
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BU of 8h9m by Molmil
Human ATP synthase state 3a subregion 3
分子名称: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ...
著者Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-10-25
公開日2023-05-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the human ATP synthase.
Mol.Cell, 83, 2023
8H9S
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BU of 8h9s by Molmil
Human ATP synthase state 1 (combined)
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-10-25
公開日2023-05-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.53 Å)
主引用文献Structure of the human ATP synthase.
Mol.Cell, 83, 2023
8H9J
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BU of 8h9j by Molmil
Human ATP synthase state2 subregion 3
分子名称: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ...
著者Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-10-25
公開日2023-05-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structure of the human ATP synthase.
Mol.Cell, 83, 2023
8H9T
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BU of 8h9t by Molmil
Human ATP synthase state 2 (combined)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ...
著者Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-10-25
公開日2023-05-31
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Structure of the human ATP synthase.
Mol.Cell, 83, 2023
8H9F
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BU of 8h9f by Molmil
Human ATP synthase state 1 subregion 3
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ATP synthase F(0) complex subunit B1, mitochondrial, ...
著者Lai, Y, Zhang, Y, Liu, F, Gao, Y, Gong, H, Rao, Z.
登録日2022-10-25
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Structure of the human ATP synthase.
Mol.Cell, 83, 2023
8F29
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BU of 8f29 by Molmil
Yeast ATP synthase in conformation-1 at pH 6
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ...
著者Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
登録日2022-11-07
公開日2024-02-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
8F39
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BU of 8f39 by Molmil
Yeast ATP synthase in conformation-2, at pH 6
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ...
著者Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
登録日2022-11-09
公開日2024-02-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
8FKJ
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BU of 8fkj by Molmil
Yeast ATP Synthase in conformation-3, at pH 6
分子名称: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ...
著者Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
登録日2022-12-21
公開日2024-01-24
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
8FL8
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BU of 8fl8 by Molmil
Yeast ATP Synthase structure in presence of MgATP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ...
著者Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M.
登録日2022-12-21
公開日2024-01-17
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
8G08
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BU of 8g08 by Molmil
Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model)
分子名称: 3-[4-(morpholin-4-yl)phenyl]-4-{[(pyridin-2-yl)methyl]amino}cyclobut-3-ene-1,2-dione, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Courbon, G.M, Rubinstein, J.L.
登録日2023-01-31
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
8G09
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BU of 8g09 by Molmil
Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase rotational state 2 (backbone model)
分子名称: 3-[4-(morpholin-4-yl)phenyl]-4-{[(pyridin-2-yl)methyl]amino}cyclobut-3-ene-1,2-dione, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Courbon, G.M, Rubinstein, J.L.
登録日2023-01-31
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
8G0B
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BU of 8g0b by Molmil
Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase FO region
分子名称: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ATP synthase subunit a, ATP synthase subunit b, ...
著者Courbon, G.M, Rubinstein, J.L.
登録日2023-01-31
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
8G0C
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BU of 8g0c by Molmil
Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 1 (backbone model)
分子名称: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Courbon, G.M, Rubinstein, J.L.
登録日2023-01-31
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
8G0E
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BU of 8g0e by Molmil
Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 3
分子名称: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Courbon, G.M, Rubinstein, J.L.
登録日2023-01-31
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
8G0A
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BU of 8g0a by Molmil
Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase rotational state 3
分子名称: 3-[4-(morpholin-4-yl)phenyl]-4-{[(pyridin-2-yl)methyl]amino}cyclobut-3-ene-1,2-dione, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Courbon, G.M, Rubinstein, J.L.
登録日2023-01-31
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
8G0D
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BU of 8g0d by Molmil
Cryo-EM structure of TBAJ-876-bound Mycobacterium smegmatis ATP synthase rotational state 2 (backbone model)
分子名称: (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2,3,6-trimethoxypyridin-4-yl)butan-2-ol, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Courbon, G.M, Rubinstein, J.L.
登録日2023-01-31
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
8G07
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BU of 8g07 by Molmil
Cryo-EM structure of SQ31f-bound Mycobacterium smegmatis ATP synthase FO region
分子名称: 3-[4-(morpholin-4-yl)phenyl]-4-{[(pyridin-2-yl)methyl]amino}cyclobut-3-ene-1,2-dione, ATP synthase subunit a, ATP synthase subunit b, ...
著者Courbon, G.M, Rubinstein, J.L.
登録日2023-01-31
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
Embo J., 42, 2023
8J0T
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BU of 8j0t by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in the apo-form
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-04-11
公開日2024-05-22
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8J0S
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BU of 8j0s by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with bedaquiline(BDQ)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-04-11
公開日2024-05-22
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8J58
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BU of 8j58 by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in the apo-form
分子名称: ATP synthase subunit a, ATP synthase subunit c
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-04-21
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024

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件を2024-09-25に公開中

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