7LQI
 
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6GYN
 | | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | | 著者 | Shintre, C.A, Pike, A.C.W, Tessitore, A, Young, M, Bushell, S.R, Strain-Damerell, C, Mukhopadhyay, S, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2018-06-30 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel
To Be Published
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7VF7
 | | Crystal Structure of HasAp with Co-octaethylporphyrin | | 分子名称: | Co-octaethylporphyrin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | 著者 | Takiguchi, A, Sakakibara, E, Sugimoto, H, Shoji, O, Shinokubo, H. | | 登録日 | 2021-09-10 | | 公開日 | 2022-09-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Crystal Structure of HasAp with Co-octaethylporphyrin
To Be Published
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1OYD
 | | Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | | 分子名称: | Acriflavine resistance protein B, DEQUALINIUM | | 著者 | Yu, E.W, MeDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | | 登録日 | 2003-04-03 | | 公開日 | 2003-05-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Science, 300, 2003
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7LQG
 | | Cryo-EM of the KFE8 thinner nanotube (class 1, C2) | | 分子名称: | KFE8 peptide | | 著者 | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | | 登録日 | 2021-02-13 | | 公開日 | 2021-06-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Deterministic chaos in the self-assembly of beta sheet nanotubes from an amphipathic oligopeptide.
Matter, 4, 2021
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6GYT
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6GYV
 | | Lariat-capping ribozyme (circular permutation form) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lariat-capping ribozyme, MAGNESIUM ION, ... | | 著者 | Masquida, B, Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E. | | 登録日 | 2018-07-02 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.50003624 Å) | | 主引用文献 | Speciation of a group I intron into a lariat capping ribozyme.
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
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7LQE
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8VJO
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6GZ6
 | | Structure of a left-handed G-quadruplex | | 分子名称: | DNA (27-MER), POTASSIUM ION | | 著者 | Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T. | | 登録日 | 2018-07-03 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | A Minimal Sequence for Left-Handed G-Quadruplex Formation.
Angew.Chem.Int.Ed.Engl., 58, 2019
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1UWB
 | | TYR 181 CYS HIV-1 RT/8-CL TIBO | | 分子名称: | 5-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE, REVERSE TRANSCRIPTASE | | 著者 | Das, K, Ding, J, Hsiou, Y, Arnold, E. | | 登録日 | 1996-11-21 | | 公開日 | 1997-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
J.Mol.Biol., 264, 1996
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5LRS
 | | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30-bp operator PrfA-box motif | | 分子名称: | DNA (30-MER), GLUTATHIONE, Listeriolysin positive regulatory factor A | | 著者 | Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. | | 登録日 | 2016-08-19 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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8VZ0
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-400 | | 分子名称: | (1S,2R,4S)-N-(cyclopropylmethyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2024-02-09 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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6GRV
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6GZC
 | | heterotetrameric katanin p60:p80 complex | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Katanin p60 ATPase-containing subunit A1, ... | | 著者 | Faltova, L, Jiang, K, Frey, D, Wu, Y, Capitani, G, Prota, A.E, Akhmanova, A, Steinmetz, M.O, Kammerer, R.A. | | 登録日 | 2018-07-03 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of a Heterotetrameric Katanin p60:p80 Complex.
Structure, 27, 2019
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5L74
 | | Plexin A2 extracellular segment domains 4-5 (PSI2-IPT2), resolution 1.36 Angstrom | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Plexin-A2, ... | | 著者 | Kong, Y, Janssen, B.J.C, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | | 登録日 | 2016-06-01 | | 公開日 | 2017-03-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
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5LPA
 | | AadA E87Q in complex with ATP, calcium and dihydrostreptomycin | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | | 著者 | Stern, A.L, Van der Verren, S.E, Selmer, M. | | 登録日 | 2016-08-12 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase fromSalmonella enterica.
J.Biol.Chem., 293, 2018
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6QNR
 | | 70S ribosome elongation complex (EC) with experimentally assigned potassium ions | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Rozov, A, Khusainov, I, Yusupov, M, Yusupova, G. | | 登録日 | 2019-02-11 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction.
Nat Commun, 10, 2019
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5L7N
 | | Plexin A1 extracellular fragment, domains 7-10 (IPT3-IPT6) | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kong, Y, Janssen, B.J.C, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | | 登録日 | 2016-06-03 | | 公開日 | 2017-03-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
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8VYT
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-411 | | 分子名称: | 4,4'-[(1R,4R,5S)-5-(2,3-dihydro-1H-indole-1-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2024-02-09 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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6GH9
 | | USP15 catalytic domain in complex with small molecule | | 分子名称: | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, DIMETHYL SULFOXIDE, Ubiquitin carboxyl-terminal hydrolase 15, ... | | 著者 | Ward, S.J, Gratton, H.E, Caulton, S.G, Emsley, J, Dreveny, I. | | 登録日 | 2018-05-06 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel.
J. Biol. Chem., 293, 2018
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6GHK
 | | Human PARP1 (ARTD1) - Catalytic domain in complex with inhibitor ME0527 | | 分子名称: | Poly [ADP-ribose] polymerase 1, SULFATE ION, ~{N}-[(1~{R})-1-(4-imidazol-1-ylphenyl)ethyl]-3-(4-oxidanylidene-1~{H}-quinazolin-2-yl)propanamide | | 著者 | Karlberg, T, Thorsell, A.G, Lindgren, A.E.G, Moche, M, Brock, J, Ekblad, T, Spjut, S, Elofsson, M, Schuler, H. | | 登録日 | 2018-05-08 | | 公開日 | 2019-05-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Human PARP1 (ARTD1) - Catalytic domain in complex with inhibitor ME0527
To Be Published
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8VZ1
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-409 | | 分子名称: | 4,4'-[(1S,4S,5R)-5-(6-methoxy-3,4-dihydroquinoline-1(2H)-sulfonyl)-7-oxabicyclo[2.2.1]hept-2-ene-2,3-diyl]diphenol, Estrogen receptor | | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2024-02-09 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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7MSF
 | | MS2 PROTEIN CAPSID/RNA COMPLEX | | 分子名称: | 5'-R(*UP*CP*GP*CP*CP*AP*AP*CP*AP*GP*GP*CP*GP*G)-3', MS2 PROTEIN CAPSID | | 著者 | Rowsell, S, Stonehouse, N.J, Convery, M.A, Adams, C.J, Ellington, A.D, Hirao, I, Peabody, D.S, Stockley, P.G, Phillips, S.E.V. | | 登録日 | 1998-05-20 | | 公開日 | 1998-11-11 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structures of a series of RNA aptamers complexed to the same protein target.
Nat.Struct.Biol., 5, 1998
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8VZP
 | | Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with k-403 | | 分子名称: | (1S,2R,4S)-N-(2-hydroxyethyl)-5,6-bis(4-hydroxyphenyl)-N-(4-methoxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor | | 著者 | Min, C.K, Nwachukwu, J.C, Hou, Y, Russo, R.J, Papa, A, Min, J, Peng, R, Kim, S.H, Ziegler, Y, Rangarajan, E.S, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. | | 登録日 | 2024-02-12 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Asymmetric allostery in estrogen receptor-alpha homodimers drives responses to the ensemble of estrogens in the hormonal milieu.
Proc.Natl.Acad.Sci.USA, 121, 2024
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