PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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6R9J	Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo) module in complex with A7 RNA 分子名称: A7 RNA, PAN2-PAN3 deadenylation complex catalytic subunit PAN2 著者 Tang, T.T.L, Stowell, J.A.W, Hill, C.H, Passmore, L.A. 登録日 2019-04-03 公開日 2019-05-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.326 Å) 主引用文献 The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases. Nat.Struct.Mol.Biol., 26, 2019
8B50	Crystal structure of a Fab fragment in complex with L-hydroxycoumarylalanine 分子名称: (2~{S})-2-azanyl-3-(7-oxidanyl-2-oxidanylidene-chromen-4-yl)propanoic acid, Fab fragment K12F9-22 - heavy chain, Fab fragment K12F9-22 - light chain, ... 著者 Meining, W, Eichinger, A, Skerra, A. 登録日 2022-09-21 公開日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Preparation and characterization of monoclonal antibodies against a non natural amino acid carrying the 7-hydroxycoumarin side chain To be published
6O9G	Open state GluA2 in complex with STZ and blocked by AgTx-636, after micelle signal subtraction 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ... 著者 Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. 登録日 2019-03-13 公開日 2019-03-20 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
6ODG	SVQIVY, Crystal Structure of a tau protein fragment 分子名称: Microtubule-associated protein tau 著者 Eisenberg, D.S, Boyer, D.R, Sawaya, M.R, Seidler, P.M. 登録日 2019-03-26 公開日 2019-10-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples. J.Biol.Chem., 294, 2019
6OR8	An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase 分子名称: 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid, IRON/SULFUR CLUSTER, PHOSPHATE ION, ... 著者 Esakova, O.A, Grove, T.L, Yennawar, N.H, Booker, S.J. 登録日 2019-04-29 公開日 2019-10-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase. J.Am.Chem.Soc., 141, 2019
8HME	head module state 1 of Tetrahymena IFT-A 分子名称: Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... 著者 Ma, Y, Wu, J, Lei, M. 登録日 2022-12-03 公開日 2023-06-14 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train. Nat Commun, 14, 2023
6OMR	Crystal structure of PtmU3 complexed with PTN substrate 分子名称: ACETATE ION, MANGANESE (II) ION, PtmU3, ... 著者 Liu, Y.C, Dong, L.B, Shen, B. 登録日 2019-04-19 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis. J.Am.Chem.Soc., 141, 2019
2PRF	THREE DIMENSIONAL SOLUTION STRUCTURE OF ACANTHAMOEBA PROFILIN I 分子名称: PROFILIN IA 著者 Archer, S.J, Vinson, V.K, Pollard, T.D, Lattman, E.E, Torchia, D.A. 登録日 1994-01-12 公開日 1994-05-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of Acanthamoeba profilin-I. J.Cell Biol., 122, 1993
6OS6	Crystal structure of CymD prenyltransferase complexed with L-tryptophan and DMSPP 分子名称: BENZOIC ACID, CHLORIDE ION, CymD prenyltransferase, ... 著者 Roose, B.W, Christianson, D.W. 登録日 2019-05-01 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD. Biochemistry, 58, 2019
6OX0	SETD3 in Complex with an Actin Peptide with Sinefungin Replacing SAH as Cofactor 分子名称: 1,2-ETHANEDIOL, Actin Peptide, Histone-lysine N-methyltransferase setd3, ... 著者 Horton, J.R, Dai, S, Cheng, X. 登録日 2019-05-13 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.755 Å) 主引用文献 Structural basis for the target specificity of actin histidine methyltransferase SETD3. Nat Commun, 10, 2019
6O4O	The structure of human interleukin 11 分子名称: CHLORIDE ION, Interleukin-11, SULFATE ION 著者 Metcalfe, R.D, Griffin, M.D.W. 登録日 2019-02-28 公開日 2020-05-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 The structure of the extracellular domains of human interleukin 11 alpha receptor reveals mechanisms of cytokine engagement. J.Biol.Chem., 295, 2020
6O52	Room temperature structure of binary complex of native hAChE with BW284c51 分子名称: 4-(5-{4-[DIMETHYL(PROP-2-ENYL)AMMONIO]PHENYL}-3-OXOPENTYL)-N,N-DIMETHYL-N-PROP-2-ENYLBENZENAMINIUM, Acetylcholinesterase 著者 Gerlits, O, Kovalevsky, A, Radic, Z. 登録日 2019-03-01 公開日 2019-06-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies. Chem.Biol.Interact., 309, 2019
7Q0D	Human carbonic anhydrase I in complex with Methyl 2-(benzenesulfonyl)-4-chloro-5-sulfamoylbenzoate 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Carbonic anhydrase 1, ... 著者 Paketuryte-Latve, V, Smirnov, A, Manakova, E, Grazulis, S. 登録日 2021-10-14 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX. Int J Mol Sci, 23, 2021
7Q0E	Human Carbonic Anhydrase II in complex with Methyl 2-(benzenesulfonyl)-4-chloro-5-sulfamoylbenzoate 分子名称: BICINE, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Paketuryte-Latve, V, Smirnov, A, Manakova, E, Grazulis, S. 登録日 2021-10-14 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX. Int J Mol Sci, 23, 2021
7Q0C	Mimic carbonic anhydrase IX in complex with Methyl 2-chloro-4-(cyclohexylsulfanyl)-5-sulfamoylbenzoate 分子名称: ACETATE ION, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Paketuryte-Latve, V, Smirnov, A, Manakova, E, Grazulis, S. 登録日 2021-10-14 公開日 2022-01-12 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX. Int J Mol Sci, 23, 2021
6OMP	Crystal structure of apo PtmU3 分子名称: ACETATE ION, MANGANESE (II) ION, PtmU3 著者 Liu, Y.C, Dong, L.B, Shen, B. 登録日 2019-04-19 公開日 2019-07-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis. J.Am.Chem.Soc., 141, 2019
6O5R	Room temperature structure of binary complex of native hAChE with oxime reactivator RS-170B 分子名称: 4-carbamoyl-1-(3-{2-[(E)-(hydroxyimino)methyl]-1H-imidazol-1-yl}propyl)pyridin-1-ium, Acetylcholinesterase, CHLORIDE ION 著者 Gerlits, O, Kovalevsky, A, Radic, Z. 登録日 2019-03-04 公開日 2019-05-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Productive reorientation of a bound oxime reactivator revealed in room temperature X-ray structures of native and VX-inhibited human acetylcholinesterase. J.Biol.Chem., 294, 2019
6Z3V	A4V mutant of human SOD1 bound with N-aryl benzoisoselenazolone derivative 13 in P21 space group 分子名称: 5-fluoranyl-~{N}-(3-morpholin-4-ylcarbonylphenyl)-2-selanyl-benzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ... 著者 Amporndanai, K, Hasnain, S.S. 登録日 2020-05-22 公開日 2020-09-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis. Ebiomedicine, 59, 2020
6OS5	Crystal structure of CymD prenyltransferase complexed with L-tryptophan 分子名称: BENZOIC ACID, CymD prenyltransferase, DIPHOSPHATE, ... 著者 Roose, B.W, Christianson, D.W. 登録日 2019-05-01 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structural Basis of Tryptophan Reverse N-Prenylation Catalyzed by CymD. Biochemistry, 58, 2019
6O5K	Murine TRIM28 Bbox1 domain 分子名称: Transcription intermediary factor 1-beta, ZINC ION 著者 Sun, Y, Keown, J.R, Goldstone, D.C. 登録日 2019-03-03 公開日 2019-06-19 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family. J.Mol.Biol., 431, 2019
4YXT	PksG, a HMG-CoA Synthase from Bacillus subtilus 分子名称: Polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG 著者 Till, M, Nair, A.V, Robson, A, Race, P.R. 登録日 2015-03-23 公開日 2016-06-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 PksG, a HMG-CoA Synthase from Bacillus subtilus To Be Published
6O5I	Menin in complex with MI-3454 分子名称: DIMETHYL SULFOXIDE, Menin, SULFATE ION, ... 著者 Linhares, B.M, Klossowski, S, Cierpicki, T, Grembecka, J. 登録日 2019-03-03 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.24025619 Å) 主引用文献 Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia. J.Clin.Invest., 130, 2020
8BYN	Chronic traumatic encephalopathy tau filaments with PET ligand flortaucipir 分子名称: 7-(6-fluoranylpyridin-3-yl)-5~{H}-pyrido[4,3-b]indole, Microtubule-associated protein tau 著者 Shi, Y, Ghetti, B, Goedert, M, Scheres, S.H.W. 登録日 2022-12-13 公開日 2023-01-11 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir. J.Mol.Biol., 435, 2023
7Q35	Crystal structure of the mutant bacteriorhodopsin pressurized with krypton 分子名称: Bacteriorhodopsin, EICOSANE, HEXANE, ... 著者 Melnikov, I, Rulev, M, Astashkin, R, Kovalev, K, Carpentier, P, Gordeliy, V, Popov, A. 登録日 2021-10-27 公開日 2022-04-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action. Commun Biol, 5, 2022
7QZR	Structure of native leukocyte myeloperoxidase in complex with the Staphyloccal Peroxidase Inhibitor SPIN from Staphylococcus aureus 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Pfanzagl, V, Brito, J.A. 登録日 2022-01-31 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation. J.Biol.Chem., 298, 2022

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