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3EY4
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BU of 3ey4 by Molmil
Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors: Reducing pregnane X receptor (PXR) activity and exploring activity in a monkey pharmacodynamic model
分子名称: (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one, 11-beta-Hydroxysteroid Dehydrogenase 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, J.D, Jordan, S.R, Li, V.
登録日2008-10-17
公開日2008-11-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors: Reducing pregnane X receptor (PXR) activity and exploring activity in a monkey pharmacodynamic model
To be Published, 2008
3EYU
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BU of 3eyu by Molmil
PFA1 Fab fragment complexed with Ror2(518-525)
分子名称: If kappa light chain, PFA1 Fab Heavy Chain, ROR2(518-525) peptide
著者Gardberg, A.S, Dealwis, C.G.
登録日2008-10-21
公開日2009-05-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structures of Abeta-related peptide--monoclonal antibody complexes.
Biochemistry, 48, 2009
3EZS
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BU of 3ezs by Molmil
Crystal structure of aminotransferase AspB (NP_207418.1) from HELICOBACTER PYLORI 26695 at 2.19 A resolution
分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, aminotransferase AspB
著者Joint Center for Structural Genomics (JCSG)
登録日2008-10-23
公開日2008-11-18
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Crystal structure of aminotransferase AspB (NP_207418.1) from HELICOBACTER PYLORI 26695 at 2.19 A resolution
To be published
3EZ4
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BU of 3ez4 by Molmil
Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase from Burkholderia pseudomallei
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-methyl-2-oxobutanoate hydroxymethyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2008-10-22
公開日2008-11-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of 3-methyl-2-oxobutanoate hydroxymethyltransferase from Burkholderia pseudomallei
To be Published
3F0H
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BU of 3f0h by Molmil
Crystal structure of Aminotransferase (RER070207000802) from Eubacterium rectale at 1.70 A resolution
分子名称: Aminotransferase, GLYCEROL, UNKNOWN LIGAND
著者Joint Center for Structural Genomics (JCSG)
登録日2008-10-24
公開日2008-11-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of Aminotransferase (RER070207000802) from Eubacterium rectale at 1.70 A resolution
To be published
3F0X
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BU of 3f0x by Molmil
Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(3,5-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine
分子名称: 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Trimethoprim-sensitive dihydrofolate reductase
著者Anderson, A.C, Frey, K.M, Liu, J, Lombardo, M.N.
登録日2008-10-27
公開日2009-10-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic Complexes of Wildtype and Mutant MRSA DHFR Reveal Interactions for Lead Design
To be Published
3F14
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Crystal structure of NTF2-like protein of unknown function (YP_680363.1) from CYTOPHAGA HUTCHINSONII ATCC 33406 at 1.45 A resolution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, TRIETHYLENE GLYCOL, uncharacterized NTF2-like protein
著者Joint Center for Structural Genomics (JCSG)
登録日2008-10-27
公開日2008-11-18
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of NTF2-like protein of unknown function (YP_680363.1) from CYTOPHAGA HUTCHINSONII ATCC 33406 at 1.45 A resolution
To be published
3F1Z
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Crystal structure of putative nucleic acid-binding lipoprotein (YP_001337197.1) from Klebsiella pneumoniae subsp. pneumoniae MGH 78578 at 2.46 A resolution
分子名称: DI(HYDROXYETHYL)ETHER, putative nucleic acid-binding lipoprotein
著者Joint Center for Structural Genomics (JCSG)
登録日2008-10-28
公開日2008-11-18
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.
Acta Crystallogr.,Sect.F, 66, 2010
3F73
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Alignment of guide-target seed duplex within an argonaute silencing complex
分子名称: ARGONAUTE, DNA (5'-D(P*DTP*DGP*DAP*DGP*DGP*DTP*DAP*DGP*DTP*DAP*DGP*DGP*DTP*DTP*DGP*DTP*DA*DTP*DAP*DGP*DT)-3'), MAGNESIUM ION, ...
著者Wang, Y, Li, H, Sheng, G, Juranek, S, Tuschl, T, Patel, D.J.
登録日2008-11-07
公開日2008-12-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex.
Nature, 456, 2008
3F6G
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BU of 3f6g by Molmil
Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type II
分子名称: Alpha-isopropylmalate synthase, ISOLEUCINE, SULFATE ION, ...
著者Zhang, P, Ma, J, Zhao, G, Ding, J.
登録日2008-11-06
公開日2009-04-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans
Biochem.J., 421, 2009
3F8H
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Crystal structure of a putative polyketide cyclase (tm1040_3560) from silicibacter sp. tm1040 at 2.00 A resolution
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2008-11-12
公開日2008-11-25
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of putative polyketide cyclase (YP_611791.1) from SILICIBACTER SP. TM1040 at 2.00 A resolution
To be published
3FA5
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BU of 3fa5 by Molmil
CRYSTAL STRUCTURE OF a DUF849 family protein (PDEN_3495) FROM PARACOCCUS DENITRIFICANS PD1222 AT 1.90 A RESOLUTION
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2008-11-14
公開日2008-12-02
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of protein of unknown function (DUF849) (YP_917261.1) from PARACOCCUS DENITRIFICANS PD1222 at 1.90 A resolution
To be published
3F8L
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BU of 3f8l by Molmil
Crystal Structure of the Effector Domain of PhnF from Mycobacterium smegmatis
分子名称: GLYCEROL, HTH-type transcriptional repressor phnF, SULFATE ION
著者Busby, J.N, Gebhard, S, Cook, G.M, Baker, E.N, Lott, S.J, Money, V.A.
登録日2008-11-12
公開日2009-11-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of PhnF, a GntR-family transcription regulator in Mycobacterium smegmatis
To be Published
3F99
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BU of 3f99 by Molmil
W354F Yersinia enterocolitica PTPase apo form
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase yopH
著者Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C.
登録日2008-11-13
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures.
J.Am.Chem.Soc., 131, 2009
3F9G
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Crystal Structure of the F140A mutant of SARS-Coronovirus 3C-like Protease at pH 6.5
分子名称: 3C-like proteinase
著者Hu, T, Li, L, Jiang, H, Shen, X.
登録日2008-11-13
公開日2009-09-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure.
Virology, 388, 2009
3F9V
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BU of 3f9v by Molmil
Crystal Structure Of A Near Full-Length Archaeal MCM: Functional Insights For An AAA+ Hexameric Helicase
分子名称: Minichromosome maintenance protein MCM
著者Chen, X.J, Brewster, A.S, Wang, G.G, Yu, X, Greenleaf, W, Tjajadi, M, Klein, M.
登録日2008-11-14
公開日2008-12-30
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (4.35 Å)
主引用文献Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicase.
Proc.Natl.Acad.Sci.USA, 105, 2008
3FCK
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Complex of UNG2 and a fragment-based design inhibitor
分子名称: 3-({[3-({[(1E)-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylidene]amino}oxy)propyl]amino}methyl)benzoic acid, Uracil-DNA glycosylase
著者Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T.
登録日2008-11-21
公開日2009-04-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Impact of linker strain and flexibility in the design of a fragment-based inhibitor
Nat.Chem.Biol., 5, 2009
3FB1
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Crystal Structure of Purine Nucleoside Phosphorylase in Complex with Ribose-1-Phosphate
分子名称: 1-O-phosphono-alpha-D-ribofuranose, ACETATE ION, Purine-nucleoside phosphorylase
著者Pereira, H.M, Garratt, R.C, Oliva, G.
登録日2008-11-18
公開日2009-11-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate.
J.Synchrotron Radiat., 18, 2011
3FEZ
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Crystal structure of uncharacterized ferredoxin fold protein related to antibiotic biosynthesis monooxygenases (YP_014836.1) from LISTERIA MONOCYTOGENES 4b F2365 at 2.10 A resolution
分子名称: uncharacterized ferredoxin fold protein related to antibiotic biosynthesis monooxygenases
著者Joint Center for Structural Genomics (JCSG)
登録日2008-12-01
公開日2008-12-16
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of uncharacterized ferredoxin fold protein related to antibiotic biosynthesis monooxygenases (YP_014836.1) from LISTERIA MONOCYTOGENES 4b F2365 at 2.10 A resolution
To be published
3FFC
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Crystal Structure of CF34 TCR in complex with HLA-B8/FLR
分子名称: Beta-2-microglobulin, CADMIUM ION, CF34 alpha chain, ...
著者Gras, S, Burrows, S.R, Kjer-Nielsen, L, Clements, C.S, Liu, Y.C, Sullivan, L.C, Brooks, A.G, Purcell, A.W, McCluskey, J, Rossjohn, J.
登録日2008-12-03
公開日2009-01-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The shaping of T cell receptor recognition by self-tolerance.
Immunity, 30, 2009
3FGY
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CRYSTAL STRUCTURE OF A NTF2-LIKE PROTEIN (BXE_B1094) FROM BURKHOLDERIA XENOVORANS LB400 AT 1.59 A RESOLUTION
分子名称: DI(HYDROXYETHYL)ETHER, UNKNOWN LIGAND, uncharacterized NTF2-like protein
著者Joint Center for Structural Genomics (JCSG)
登録日2008-12-08
公開日2008-12-23
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Crystal structure of NTF2-like protein of unknown function. (YP_554211.1) from BURKHOLDERIA XENOVORANS LB400 at 1.59 A resolution
To be published
3EYE
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Crystal structure of PTS system N-acetylgalactosamine-specific IIB component 1 from Escherichia coli
分子名称: PTS system N-acetylgalactosamine-specific IIB component 1
著者Bonanno, J.B, Dickey, M, Bain, K.T, Do, J, Sampathkumar, P, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-10-20
公開日2008-11-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of PTS system N-acetylgalactosamine-specific IIB component 1 from Escherichia coli
To be Published
3FK9
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Crystal structure of mMutator MutT protein from Bacillus halodurans
分子名称: Mutator MutT protein
著者Bonanno, J.B, Freeman, J, Bain, K.T, Hu, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-12-16
公開日2009-01-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of mMutator MutT protein from Bacillus halodurans
To be Published
3F0S
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Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(3,5-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine
分子名称: 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Trimethoprim-sensitive dihydrofolate reductase
著者Anderson, A.C, Frey, K.M, Liu, J, Lombardo, M.N.
登録日2008-10-25
公開日2009-10-06
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic Complexes of Wildtype and Mutant MRSA DHFR Reveal Interactions for Lead Design
To be Published
3FN4
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Apo-form of NAD-dependent formate dehydrogenase from bacterium Moraxella sp.C-1 in closed conformation
分子名称: GLYCEROL, NAD-dependent formate dehydrogenase, SULFATE ION
著者Shabalin, I.G, Polyakov, K.M, Filippova, E.V, Dorovatovskiy, P.V, Tikhonova, T.V, Sadykhov, E.G, Tishkov, V.I, Popov, V.O.
登録日2008-12-23
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structures of the apo and holo forms of formate dehydrogenase from the bacterium Moraxella sp. C-1: towards understanding the mechanism of the closure of the interdomain cleft
Acta Crystallogr.,Sect.D, 65, 2009

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