3IPT
 
 | |
3IUU
 | |
3IV3
 | | The Structure of a putative tagatose 1,6-aldolase from Streptococcus mutans | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Cuff, M.E, Hatzos, C, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-08-31 | | 公開日 | 2009-09-22 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Structure of a putative tagatose 1,6-aldolase from Streptococcus mutans
TO BE PUBLISHED
|
|
3IS5
 | | Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720 | | 分子名称: | CALCIUM ION, Calcium-dependent protein kinase, GLYCEROL, ... | | 著者 | Wernimont, A.K, Artz, J.D, Senisterra, G, MacKenzie, F, Hutchinson, A, Kozieradzki, I, Cossar, D, Bochkarev, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-08-25 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720
To be Published
|
|
3IVI
 | | Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents | | 分子名称: | Beta-secretase 1, GLYCEROL, N-[(1S,2R)-3-{[(5S)-5-(3-tert-butylphenyl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide, ... | | 著者 | Pan, H. | | 登録日 | 2009-09-01 | | 公開日 | 2010-01-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
3ITB
 | | Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in complex with a substrate fragment | | 分子名称: | D-alanyl-D-alanine carboxypeptidase DacC, Peptidoglycan substrate (AMV)A(FGA)K(DAL)(DAL), SULFATE ION, ... | | 著者 | Chen, Y, Zhang, W, Shi, Q, Hesek, D, Lee, M, Mobashery, S, Shoichet, B.K. | | 登録日 | 2009-08-27 | | 公開日 | 2009-10-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structures of penicillin-binding protein 6 from Escherichia coli.
J.Am.Chem.Soc., 131, 2009
|
|
3IW7
 | | Human p38 MAP Kinase in Complex with an Imidazo-pyridine | | 分子名称: | 2-({4-[(4-benzylpiperidin-1-yl)carbonyl]benzyl}sulfanyl)-3H-imidazo[4,5-c]pyridine, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside | | 著者 | Gruetter, C, Simard, J.R, Rauh, D. | | 登録日 | 2009-09-02 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38alpha
J.Am.Chem.Soc., 131, 2009
|
|
3IV0
 | |
3IW4
 | | Crystal structure of PKC alpha in complex with NVP-AEB071 | | 分子名称: | 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione, Protein kinase C alpha type | | 著者 | Stark, W, Rummel, G, Strauss, A, Cowan-Jacob, S.W. | | 登録日 | 2009-09-02 | | 公開日 | 2009-11-03 | | 最終更新日 | 2021-11-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypes
J.Med.Chem., 52, 2009
|
|
3IXP
 | |
3EXT
 | | Crystal structure of KGPDC from Streptococcus mutans | | 分子名称: | MAGNESIUM ION, RmpD (Hexulose-6-phosphate synthase) | | 著者 | Liu, X, Li, G.L, Li, L.F, Su, X.D. | | 登録日 | 2008-10-17 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Open-closed conformational change revealed by the crystal structures of 3-keto-L-gulonate 6-phosphate decarboxylase from Streptococcus mutans
Biochem.Biophys.Res.Commun., 381, 2009
|
|
3EVS
 | |
3EVV
 | | Crystal Structure of Calcium bound dimeric GCAMP2 (#2) | | 分子名称: | CALCIUM ION, Myosin light chain kinase, Green fluorescent protein, ... | | 著者 | Wang, Q, Shui, B, Kotlikoff, M.I, Sondermann, H. | | 登録日 | 2008-10-13 | | 公開日 | 2008-12-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Calcium Sensing by GCaMP2.
Structure, 16, 2008
|
|
3EW3
 | | the 1:2 complex between a Nterminal elongated prolactin and the extra cellular domain of the rat prolactin receptor | | 分子名称: | Prolactin, Prolactin receptor | | 著者 | Broutin, I, Jomain, J.B, England, P, Goffin, V. | | 登録日 | 2008-10-14 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.
J.Biol.Chem., 285, 2010
|
|
3EY6
 | | Crystal structure of the FK506-binding domain of human FKBP38 | | 分子名称: | FK506-binding protein 8 | | 著者 | Parthier, C, Maestre-Martinez, M, Neumann, P, Edlich, F, Fischer, G, Luecke, C, Stubbs, M.T. | | 登録日 | 2008-10-19 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding.
J.Mol.Recognit., 24, 2011
|
|
3EXF
 | | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex | | 分子名称: | MAGNESIUM ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, ... | | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | | 登録日 | 2008-10-16 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | | 主引用文献 | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.
Structure, 16, 2008
|
|
3EWI
 | | Structural analysis of the C-terminal domain of murine CMP-Sialic acid Synthetase | | 分子名称: | N-acylneuraminate cytidylyltransferase | | 著者 | Oschlies, M, Dickmanns, A, Stummeyer, K, Gerardy-Schahn, R, Ficner, R, Muenster-Kuehnel, A.K. | | 登録日 | 2008-10-15 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme.
J.Mol.Biol., 393, 2009
|
|
3EXG
 | | Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex | | 分子名称: | POTASSIUM ION, Pyruvate dehydrogenase E1 component subunit alpha, somatic form, ... | | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Machius, M, Li, J, Chuang, D.T. | | 登録日 | 2008-10-16 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.011 Å) | | 主引用文献 | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops.
Structure, 16, 2008
|
|
3EZY
 | | Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Dehydrogenase | | 著者 | Ramagopal, U.A, Toro, R, Freeman, J, Chang, S, Maletic, M, Gheyi, T, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2008-10-24 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Crystal structure of probable dehydrogenase TM_0414 from Thermotoga maritima
To be published
|
|
3F10
 | |
3F3T
 | | Kinase domain of cSrc in complex with inhibitor RL38 (Type III) | | 分子名称: | 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea, Proto-oncogene tyrosine-protein kinase Src | | 著者 | Gruetter, C, Klueter, S, Getlik, M, Rauh, D. | | 登録日 | 2008-10-31 | | 公開日 | 2009-03-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A new screening assay for allosteric inhibitors of cSrc
Nat.Chem.Biol., 5, 2009
|
|
3EWC
 | | Crystal Structure of adenosine deaminase from Plasmodial vivax in complex with MT-coformycin | | 分子名称: | (8R)-3-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol, Adenosine deaminase, ZINC ION | | 著者 | Schramm, V.L, Almo, S.C, Cassera, M.B, Ho, M.C. | | 登録日 | 2008-10-14 | | 公開日 | 2009-09-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.
Biochemistry, 48, 2009
|
|
3EXO
 | | Crystal structure of BACE1 bound to inhibitor | | 分子名称: | Beta-secretase 1, GLYCEROL, N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide, ... | | 著者 | Allison, T.J. | | 登録日 | 2008-10-16 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
3EXX
 | |
3EY5
 | | Putative acetyltransferase from GNAT family from Bacteroides thetaiotaomicron. | | 分子名称: | Acetyltransferase-like, GNAT family, SULFATE ION | | 著者 | Osipiuk, J, Bigelow, L, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-10-17 | | 公開日 | 2008-11-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | X-ray crystal structure of putative acetyltransferase from GNAT family from Bacteroides thetaiotaomicron.
To be Published
|
|
