3ILJ
| Crystal structure of E. coli HPPK(D95A) in complex with MgAMPCPP | 分子名称: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, CHLORIDE ION, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-08-07 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published
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5K54
| Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state | 分子名称: | Fructose-1,6-bisphosphatase isozyme 2 | 著者 | Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D. | 登録日 | 2016-05-23 | 公開日 | 2017-06-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.717 Å) | 主引用文献 | Structural studies of human muscle FBPase To Be Published
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3MHR
| 14-3-3 sigma in complex with YAP pS127-peptide | 分子名称: | 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... | 著者 | Schumacher, B, Skwarczynska, M, Rose, R, Ottmann, C. | 登録日 | 2010-04-08 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structure of a 14-3-3[sigma]-YAP phosphopeptide complex at 1.15 A resolution Acta Crystallogr.,Sect.F, 66, 2010
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2WDW
| The Native Crystal Structure of the Primary Hexose Oxidase (Dbv29) in Antibiotic A40926 Biosynthesis | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, PUTATIVE HEXOSE OXIDASE | 著者 | Liu, Y.-C, Li, Y.-S, Lyu, S.-Y, Chen, Y.-H, Chan, H.-C, Huang, C.-J, Huang, Y.-T, Chen, G.-H, Chou, C.-C, Tsai, M.-D, Li, T.-L. | 登録日 | 2009-03-27 | 公開日 | 2010-04-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Interception of Teicoplanin Oxidation Intermediates Yields New Antimicrobial Scaffolds Nat.Chem.Biol., 7, 2011
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3SWK
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3GD3
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6KO6
| Crystal structure of AMPPNP bound Cka1 from C. neoformans | 分子名称: | CMGC/CK2 protein kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Cho, H.S, Yoo, Y. | 登録日 | 2019-08-08 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural analysis of fungal pathogenicity-related casein kinase alpha subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans. Sci Rep, 9, 2019
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5TZ1
| Crystal structure of sterol 14-alpha demethylase (CYP51) from Candida albicans in complex with the tetrazole-based antifungal drug candidate VT1161 (VT1) | 分子名称: | (R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14-alpha demethylase | 著者 | Hargrove, T, Wawrzak, Z, Lepesheva, G. | 登録日 | 2016-11-21 | 公開日 | 2017-03-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural analyses of Candida albicans sterol 14 alpha-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis. J. Biol. Chem., 292, 2017
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2WTY
| Crystal structure of the homodimeric MafB in complex with the T-MARE binding site | 分子名称: | DNA (5'-D(*TP*AP*AP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP *GP*CP*AP*AP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*TP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP *GP*CP*AP*AP*TP*T)-3'), MAGNESIUM ION, ... | 著者 | Consani Textor, L, Holton, S, Wilmanns, M. | 登録日 | 2009-09-25 | 公開日 | 2010-12-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Design of a bZIP Transcription Factor with Homo/Heterodimer-Induced DNA-Binding Preference. Structure, 22, 2014
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3DRM
| 2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin | 分子名称: | Alpha-1-antitrypsin | 著者 | Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E. | 登録日 | 2008-07-11 | 公開日 | 2009-03-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design. J.Mol.Biol., 387, 2009
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3BGC
| HIV-1 protease in complex with a benzyl decorated oligoamine | 分子名称: | CHLORIDE ION, N,N'-(iminodiethane-2,1-diyl)bis(4-amino-N-benzylbenzenesulfonamide), Protease | 著者 | Boettcher, J, Blum, A, Sammet, B, Heine, A, Diederich, W.E, Klebe, G. | 登録日 | 2007-11-26 | 公開日 | 2008-09-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Achiral oligoamines as versatile tool for the development of aspartic protease inhibitors Bioorg.Med.Chem., 16, 2008
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1CLF
| CLOSTRIDIUM PASTEURIANUM FERREDOXIN | 分子名称: | FERREDOXIN, IRON/SULFUR CLUSTER | 著者 | Bertini, I, Donaire, A, Feinberg, B.A, Luchinat, C, Piccioli, M, Yuan, H. | 登録日 | 1995-06-21 | 公開日 | 1996-01-29 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the oxidized 2[4Fe-4S] ferredoxin from Clostridium pasteurianum. Eur.J.Biochem., 232, 1995
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5UW5
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3S7K
| Structure of thrombin mutant Y225P in the E form | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, POTASSIUM ION, Prothrombin | 著者 | Niu, W, Chen, Z, Gandhi, P, Vogt, A, Pozzi, N, Pele, L.A, Zapata, F, Di Cera, E. | 登録日 | 2011-05-26 | 公開日 | 2011-07-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like Protease. Biochemistry, 50, 2011
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5CEL
| CBH1 (E212Q) CELLOTETRAOSE COMPLEX | 分子名称: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ... | 著者 | Divne, C, Stahlberg, J, Jones, T.A. | 登録日 | 1997-09-24 | 公開日 | 1997-12-24 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High-resolution crystal structures reveal how a cellulose chain is bound in the 50 A long tunnel of cellobiohydrolase I from Trichoderma reesei. J.Mol.Biol., 275, 1998
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2Y92
| Crystal structure of MAL adaptor protein | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN, | 著者 | Valkov, E, Stamp, A, Martin, J.L, Kobe, B. | 登録日 | 2011-02-11 | 公開日 | 2011-09-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection. Proc.Natl.Acad.Sci.USA, 108, 2011
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6ANQ
| STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) TERNARY COMPLEX WITH A DOUBLE STRANDED DNA AND AN INCOMING D4TTP AT PH 8.5 | 分子名称: | 2',3'-DEHYDRO-2',3'-DEOXY-THYMIDINE 5'-TRIPHOSPHATE, DNA PRIMER (5'- D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*GP)-3'), DNA TEMPLATE (5'- D(*AP*TP*GP*AP*AP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), ... | 著者 | Martinez, S.E, Das, K, Arnold, E. | 登録日 | 2017-08-14 | 公開日 | 2018-08-15 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.586 Å) | 主引用文献 | Structure of HIV-1 reverse transcriptase/d4TTP complex: Novel DNA cross-linking site and pH-dependent conformational changes. Protein Sci., 28, 2019
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2P8W
| Fitted structure of eEF2 in the 80S:eEF2:GDPNP cryo-EM reconstruction | 分子名称: | Elongation factor 2, Elongation factor Tu-B, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J. | 登録日 | 2007-03-23 | 公開日 | 2007-05-08 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (11.3 Å) | 主引用文献 | Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation. Embo J., 26, 2007
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3KD5
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2YQ0
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2YPZ
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1NOY
| DNA POLYMERASE (E.C.2.7.7.7)/DNA COMPLEX | 分子名称: | DNA (5'-D(*TP*TP*T)-3'), MANGANESE (II) ION, PROTEIN (DNA POLYMERASE (E.C.2.7.7.7)), ... | 著者 | Wang, J, Yu, P, Lin, T.C, Konigsberg, W.H, Steitz, T.A. | 登録日 | 1996-02-16 | 公開日 | 1996-10-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions. Biochemistry, 35, 1996
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3GGV
| HIV Protease, pseudo-symmetric inhibitors | 分子名称: | V-1 protease, methyl [(1S)-1-{[(1R,3S,4S)-3-hydroxy-4-{[(2S)-2-(3-{[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]methyl}-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-3,3-dimethylbutanoyl]amino}-5-phenyl-1-(4-pyridin-2-ylbenzyl)pentyl]carbamoyl}-2,2-dimethylpropyl]carbamate | 著者 | Stoll, V.S. | 登録日 | 2009-03-02 | 公開日 | 2009-05-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | 2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus
protease inhibitors (A-792611 and A-790742) with potential for convenient
dosing and reduced side effects. J.Med.Chem., 52, 2009
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2YPY
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2WOF
| EDTA treated E. coli copper amine oxidase | 分子名称: | COPPER (II) ION, PRIMARY AMINE OXIDASE, SODIUM ION | 著者 | Smith, M.A, Pirrat, P, Pearson, A.R, Knowles, P.F, Phillips, S.E.V, McPherson, M.J. | 登録日 | 2009-07-23 | 公開日 | 2010-05-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Exploring the Roles of the Metal Ions in Escherichia Coli Copper Amine Oxidase. Biochemistry, 49, 2010
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