PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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1OUH	CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V74A MUTANT 分子名称: LYSOZYME, SODIUM ION 著者 Takano, K, Yamagata, Y, Fujii, S, Yutani, K. 登録日 1996-08-23 公開日 1997-02-12 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants. Biochemistry, 36, 1997
3PJ8	Structure of CDK2 in complex with a Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine. 分子名称: (2R)-2-{[7-(benzylamino)-3-(propan-2-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]amino}butan-1-ol, Cell division protein kinase 2 著者 McNae, I.W, Jorda, R, Havlicek, L, Strnad, M, Voller, J, Walkinshaw, M.D, Krystof, V. 登録日 2010-11-09 公開日 2011-04-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity. J.Med.Chem., 54, 2011
4RXY	Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa 分子名称: Carbonic anhydrase, GLYCEROL, ZINC ION 著者 Pinard, M.A, Mckenna, R. 登録日 2014-12-12 公開日 2015-06-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa. Bioorg.Med.Chem., 23, 2015
1OUF	CONTRIBUTION OF HYDROPHOBIC RESIDUES TO THE STABILITY OF HUMAN LYSOZYME: X-RAY STRUCTURE OF THE V130A MUTANT 分子名称: LYSOZYME, SODIUM ION 著者 Takano, K, Yamagata, Y, Fujii, S, Yutani, K. 登録日 1996-08-23 公開日 1997-02-12 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Contribution of the hydrophobic effect to the stability of human lysozyme: calorimetric studies and X-ray structural analyses of the nine valine to alanine mutants. Biochemistry, 36, 1997
4RKK	Structure of a product bound phosphatase 分子名称: Laforin, PHOSPHATE ION, alpha-D-glucopyranose, ... 著者 Vander Kooi, C.W. 登録日 2014-10-13 公開日 2015-01-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease. Mol.Cell, 57, 2015
4RPX	Precatalytic ternary complex of Human DNA Polymerase Beta With Gapped DNA Containing an 8-oxo-7,8-dihydro-Guanine (8-oxoG) and dCTP in the presence of CaCl2 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ACETATE ION, CALCIUM ION, ... 著者 Vyas, R, Suo, Z. 登録日 2014-10-31 公開日 2015-04-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Viewing Human DNA Polymerase beta Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography. J.Am.Chem.Soc., 137, 2015
1O0C	CRYSTAL STRUCTURE OF L-GLUTAMATE AND AMPCPP BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE 分子名称: ADENOSINE MONOPHOSPHATE, GLUTAMIC ACID, Glutaminyl tRNA, ... 著者 Bullock, T.L, Perona, J.J. 登録日 2003-02-20 公開日 2003-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Amino Acid Discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants J.Mol.Biol., 328, 2003
1AHT	CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND P-AMIDINOPHENYLPYRUVATE AT 1.6 ANGSTROMS RESOLUTION 分子名称: (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), ... 著者 Chen, Z. 登録日 1995-03-17 公開日 1996-03-17 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution. Arch.Biochem.Biophys., 322, 1995
5KP7	Crystal Structure of the Curacin Biosynthetic Pathway HMG Synthase in Complex with Holo Donor-ACP 分子名称: 4'-PHOSPHOPANTETHEINE, CurB, CurD, ... 著者 Maloney, F.P, Smith, J.L. 登録日 2016-07-02 公開日 2016-08-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Anatomy of the beta-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate. Proc.Natl.Acad.Sci.USA, 113, 2016
1O3Z	HIV-1 DIS(MAL) DUPLEX RU HEXAMINE-SOAKED 分子名称: HIV-1 DIS(MAL) GENOMIC RNA, MAGNESIUM ION, RUTHENIUM ION 著者 Ennifar, E, Walter, P, Dumas, P. 登録日 2003-05-16 公開日 2003-05-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A crystallographic study of the binding of 13 metal ions to two related RNA duplexes. Nucleic Acids Res., 31, 2003
1HDT	STRUCTURE OF A RETRO-BINDING PEPTIDE INHIBITOR COMPLEXED WITH HUMAN ALPHA-THROMBIN 分子名称: ALPHA-THROMBIN, HIRUGEN PEPTIDE, methyl N-(4-carbamimidamidobutanoyl)-L-phenylalanyl-L-allothreonyl-L-phenylalaninate 著者 Tabernero, L, Sack, J. 登録日 1994-07-25 公開日 1995-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of a retro-binding peptide inhibitor complexed with human alpha-thrombin. J.Mol.Biol., 246, 1995
2PUQ	Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor 分子名称: CALCIUM ION, Coagulation factor VII, TRP-TYR-THR-ARG CHLOROMETHYLKETONE INHIBITOR, ... 著者 Bjelke, J.R, Rasmussen, H.B. 登録日 2007-05-09 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa Biochem.J., 405, 2007
1BI9	RETINAL DEHYDROGENASE TYPE TWO WITH NAD BOUND 分子名称: CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, RETINAL DEHYDROGENASE TYPE II 著者 Newcomer, M.E, Lamb, A.L. 登録日 1998-06-23 公開日 1999-07-22 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structure of retinal dehydrogenase type II at 2.7 A resolution: implications for retinal specificity. Biochemistry, 38, 1999
4TGF	SOLUTION STRUCTURES OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA DERIVED FROM 1*H NMR DATA 分子名称: DES-VAL-1,VAL-2,TRANSFORMING GROWTH FACTOR, ALPHA 著者 Kline, T.P, Brown, F.K, Brown, S.C, Jeffs, P.W, Kopple, K.D, Mueller, L. 登録日 1990-06-13 公開日 1991-10-15 最終更新日 2017-11-29 実験手法 SOLUTION NMR 主引用文献 Solution structures of human transforming growth factor alpha derived from 1H NMR data. Biochemistry, 29, 1990
8R8D	Cryo-EM structure of coagulation factor beta-XIIa in complex with the garadacimab Fab fragment (symmetric dimer) 分子名称: Coagulation factor XII, Garadacimab heavy chain variable region, Garadacimab light chain variable region, ... 著者 Drulyte, I. 登録日 2023-11-29 公開日 2023-12-13 最終更新日 2024-09-04 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for the inhibition of beta FXIIa by garadacimab. Structure, 2024
6UOM	Y271G DNA polymerase beta ternary complex with templating adenine and incoming r8-oxo-GTP 分子名称: 1,2-ETHANEDIOL, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Smith, M.R, Freudenthal, B.D. 登録日 2019-10-15 公開日 2020-01-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta. J.Biol.Chem., 295, 2020
1FIW	THREE-DIMENSIONAL STRUCTURE OF BETA-ACROSIN FROM RAM SPERMATOZOA 分子名称: BETA-ACROSIN HEAVY CHAIN, BETA-ACROSIN LIGHT CHAIN, P-AMINO BENZAMIDINE, ... 著者 Tranter, R, Read, J.A, Jones, R, Brady, R.L. 登録日 2000-08-07 公開日 2000-11-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Effector sites in the three-dimensional structure of mammalian sperm beta-acrosin. Structure Fold.Des., 8, 2000
7MKF	Paired helical tau filament extracted from PrP-CAA Patient brain tissue | tau filament | PHF Tau 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Hoq, M.R. 登録日 2021-04-23 公開日 2021-07-28 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of Tau filaments in Prion protein amyloidoses. Acta Neuropathol, 142, 2021
1R4M	APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex 分子名称: Ubiquitin-like protein NEDD8, ZINC ION, amyloid beta precursor protein-binding protein 1, ... 著者 Walden, H, Podgorski, M.S, Holton, J.M, Schulman, B.A. 登録日 2003-10-07 公開日 2003-12-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1. Mol.Cell, 12, 2003
7MKH	Paired helical tau filament extracted from GSS Patient brain tissue | tau filament from Gerstmann Straussler Scheinker disease | PHF Tau 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Hoq, M.R. 登録日 2021-04-23 公開日 2021-07-28 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of Tau filaments in Prion protein amyloidoses. Acta Neuropathol, 142, 2021
7MKG	Straight tau filament extracted from PrP-CAA Patient brain tissue | tau filament | SF Tau 分子名称: Isoform Tau-F of Microtubule-associated protein tau 著者 Hoq, M.R. 登録日 2021-04-23 公開日 2021-07-28 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Structure of Tau filaments in Prion protein amyloidoses. Acta Neuropathol, 142, 2021
5JUM	Crystal Structure of Human DNA Polymerase Eta Inserting dCTP Opposite N-(2'-deoxyguanosin-8- yl)-3-aminobenzanthrone (C8-dG-ABA) 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Patra, A, Politica, D.A, Stone, M.P, Egli, M. 登録日 2016-05-10 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase eta. Chembiochem, 17, 2016
5L3K	Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase in a ternary complex with ADP and fructose-6-phosphate 分子名称: 1,2-ETHANEDIOL, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Mendes, V, Verma, N, Blaszczyk, M, Blundell, T.L. 登録日 2016-05-23 公開日 2017-06-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.305 Å) 主引用文献 Mycobacterial OtsA Structures Unveil Substrate Preference Mechanism and Allosteric Regulation by 2-Oxoglutarate and 2-Phosphoglycerate. Mbio, 10, 2019
1PLF	THE THREE-DIMENSIONAL STRUCTURE OF BOVINE PLATELET FACTOR 4 AT 3.0 ANGSTROMS RESOLUTION 分子名称: PLATELET FACTOR 4, TETRACYANONICKELATE ION 著者 St Charles, R, Edwards, B.F.P. 登録日 1993-10-20 公開日 1994-01-31 最終更新日 2019-08-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The three-dimensional structure of bovine platelet factor 4 at 3.0-A resolution. J.Biol.Chem., 264, 1989
7N0H	CryoEM structure of SARS-CoV-2 spike protein (S-6P, 2-up) in complex with sybodies (Sb45) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... 著者 Jiang, J, Huang, R, Margulies, D. 登録日 2021-05-25 公開日 2021-06-02 最終更新日 2021-10-20 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Structures of synthetic nanobody-SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction. J.Biol.Chem., 297, 2021

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