PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3IJH	Structure of S67-27 in Complex with Ko 分子名称: Immunoglobulin heavy chain (IGG3), Immunoglobulin light chain (IGG3), MAGNESIUM ION, ... 著者 Brooks, C.L, Blackler, R.J, Evans, S.V. 登録日 2009-08-04 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The role of CDR H3 in antibody recognition of a synthetic analog of a lipopolysaccharide antigen. Glycobiology, 20, 2010
3IK3	AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance 分子名称: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Proto-oncogene tyrosine-protein kinase ABL1 著者 Zhou, T. 登録日 2009-08-05 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell, 16, 2009
3IK6	Crystal structure of the AMPA subunit GluR2 bound to the allosteric modulator, chlorothiazide 分子名称: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, GLUTAMIC ACID, Glutamate receptor 2, ... 著者 Ptak, C.P, Ahmed, A.H, Oswald, R.E. 登録日 2009-08-05 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Probing the allosteric modulator binding site of GluR2 with thiazide derivatives Biochemistry, 48, 2009
3ILI	Crystal structure of E. coli HPPK(D95A) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, ACETATE ION, ... 著者 Blaszczyk, J, Li, Y, Yan, H, Ji, X. 登録日 2009-08-07 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural and functional roles of residues D95 and D97 in E. coli HPPK To be Published
3ILR	Structure of Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product 分子名称: 1,2-ETHANEDIOL, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(4-1)-4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid, 4-deoxy-2-O-sulfo-beta-D-erythro-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ... 著者 Garron, M.L, Cygler, M, Shaya, D. 登録日 2009-08-07 公開日 2009-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural snapshots of heparin depolymerization by heparin lyase I. J.Biol.Chem., 284, 2009
3IMS	Transthyretin in complex with 2,6-dibromo-4-(2,6-dichlorophenethyl)phenol 分子名称: 2,6-dibromo-4-[2-(2,6-dichlorophenyl)ethyl]phenol, Transthyretin 著者 Connelly, S, Wilson, I.A. 登録日 2009-08-11 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity. J.Am.Chem.Soc., 132, 2010
3ILZ	Structure of TR-alfa bound to selective thyromimetic GC-1 in P212121 space group 分子名称: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid 著者 Aparicio, R, Polikarpov, L, Bleicher, L. 登録日 2009-08-07 公開日 2010-04-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms. Bmc Struct.Biol., 8, 2008
3IM9	Crystal structure of MCAT from Staphylococcus aureus 分子名称: ACETATE ION, CALCIUM ION, Malonyl CoA-acyl carrier protein transacylase, ... 著者 Hong, S.K, Kim, K.H, Park, J.K, Kim, Y.M, Kim, E.E. 登録日 2009-08-10 公開日 2010-06-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 New design platform for malonyl-CoA-acyl carrier protein transacylase Febs Lett., 584, 2010
3IOI	Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (1GW) 分子名称: 5-(2-FORMYLTHIEN-5-YL)-URIDINE-5'-DIPHOSPHATE-ALPHA-D-GALACTOSE, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... 著者 Pesnot, T, Jorgensen, R, Palcic, M.M, Wagner, G.K. 登録日 2009-08-14 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural and mechanistic basis for a new mode of glycosyltransferase inhibition. Nat.Chem.Biol., 6, 2010
3IOY	Structure of putative short-chain dehydrogenase (Saro_0793) from Novosphingobium aromaticivorans 分子名称: Short-chain dehydrogenase/reductase SDR 著者 Ramagopal, U.A, Morano, C, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-08-15 公開日 2010-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure of putative short-chain dehydrogenase (Saro_0793) from Novosphingobium aromaticivorans To be published
3IPP	crystal structure of sulfur-free YnjE 分子名称: GLYCEROL, PHOSPHATE ION, Putative thiosulfate sulfurtransferase ynjE, ... 著者 Haenzelmann, P, Kuper, J, Schindelin, H. 登録日 2009-08-18 公開日 2009-12-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of YnjE from Escherichia coli, a sulfurtransferase with three rhodanese domains. Protein Sci., 18, 2009
3IQP	SAM-I riboswitch from T. tencongensis variant A94G apo form 分子名称: BARIUM ION, SAM-I riboswitch 著者 Montange, R.K, Batey, R.T. 登録日 2009-08-20 公開日 2010-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Free state conformational sampling of the SAM-I riboswitch aptamer domain. Structure, 18, 2010
3IP0	Crystal structure of E. coli HPPK in complex with MgAMPCPP and 6-hydroxymethylpterin/6-carboxypterin 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-CARBOXYPTERIN, 6-HYDROXYMETHYLPTERIN, ... 著者 Blaszczyk, J, Ji, X. 登録日 2009-08-15 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (0.89 Å) 主引用文献 Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydroptein pyrophosphokinase: Crystallographic studies Biochemistry, 42, 2003
3IVH	Design and Synthesis of Potent BACE-1 Inhibitors with Cellular Activity: Structure-Activity Relationship of P1 Substituents 分子名称: Beta-secretase 1, N-[(1S,2R)-3-{[1-(3-tert-butylphenyl)cyclohexyl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide 著者 Pan, H. 登録日 2009-09-01 公開日 2010-01-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents. Bioorg.Med.Chem.Lett., 19, 2009
3IVS	Homocitrate Synthase Lys4 分子名称: COBALT (II) ION, Homocitrate synthase, mitochondrial, ... 著者 Bulfer, S.L, Scott, E.M, Couture, J.-F, Pillus, L, Trievel, R.C. 登録日 2009-09-01 公開日 2009-09-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J.Biol.Chem., 284, 2009
3ISF	Structure of non-mineralized Bfrb (as-isolated) from Pseudomonas aeruginosa to 2.07A Resolution 分子名称: Bacterioferritin, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Lovell, S, Weeratunga, S.K, Battaile, K.P, Rivera, M. 登録日 2009-08-25 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural Studies of Bacterioferritin B from Pseudomonas aeruginosa Suggest a Gating Mechanism for Iron Uptake via the Ferroxidase Center Biochemistry, 49, 2010
3I72	Structural characterization for the nucleotide binding ability of subunit A with SO4 of the A1AO ATP synthase 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, A-TYPE ATP SYNTHASE CATALYTIC SUBUNIT A, ... 著者 Manimekalai, S.M.S, Kumar, A, Balakrishna, A.M, Gruber, G. 登録日 2009-07-07 公開日 2010-01-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.47 Å) 主引用文献 Nucleotide binding states of subunit A of the A-ATP synthase and the implication of P-loop switch in evolution. J.Mol.Biol., 396, 2010
3I7D	Crystal structure of sugar phosphate isomerase from a cupin superfamily SPO2919 from Silicibacter pomeroyi (YP_168127.1) from SILICIBACTER POMEROYI DSS-3 at 2.30 A resolution 分子名称: ACETATE ION, CACODYLATE ION, CHLORIDE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-07-08 公開日 2009-07-21 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of sugar phosphate isomerase from a cupin superfamily SPO2919 from Silicibacter pomeroyi (YP_168127.1) from SILICIBACTER POMEROYI DSS-3 at 2.30 A resolution To be published
3I8P	Crystal structure of E. coli FabF(C163A) in complex with Platensimycin A1 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Platensimycin A1 著者 Soisson, S.M, Parthsarathy, G. 登録日 2009-07-09 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis. Bioorg.Med.Chem.Lett., 19, 2009
3I80	Protein Tyrosine Phosphatase 1B - Transition state analog for the second catalytic step 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1, ... 著者 Brandao, T.A.S, Johnson, S.J, Hengge, A.C. 登録日 2009-07-09 公開日 2010-03-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Insights into the reaction of protein-tyrosine phosphatase 1B: crystal structures for transition state analogs of both catalytic steps. J.Biol.Chem., 285, 2010
3I96	Ethanolamine Utilization Microcompartment Shell Subunit, EutS 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CHLORIDE ION, Ethanolamine utilization protein eutS, ... 著者 Tanaka, S, Sawaya, M.R, Yeates, T.O. 登録日 2009-07-10 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and Mechanisms of a Protein-Based Organelle in Escherichia coli. Science, 327, 2010
3I9G	Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate 分子名称: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, CALCIUM ION, MAGNESIUM ION, ... 著者 Huxford, T. 登録日 2009-07-10 公開日 2009-09-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. Proc.Natl.Acad.Sci.USA, 106, 2009
3I9V	Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus, oxidized, 2 mol/ASU 分子名称: CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... 著者 Sazanov, L.A, Berrisford, J.M. 登録日 2009-07-13 公開日 2009-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for the mechanism of respiratory complex I J.Biol.Chem., 284, 2009
3I9Y	Crystal structure of the V. parahaemolyticus histidine kinase sensor TorS sensor domain 分子名称: Sensor protein 著者 Moore, J.O, Hendrickson, W.A. 登録日 2009-07-13 公開日 2009-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Structural analysis of sensor domains from the TMAO-responsive histidine kinase receptor TorS Structure, 17, 2009
3IBO	Pseudomonas aeruginosa E2Q/H83Q/T126H-azurin RE(PHEN)(CO)3 分子名称: (1,10 PHENANTHROLINE)-(TRI-CARBON MONOXIDE) RHENIUM (I), Azurin, COPPER (II) ION 著者 Gradinaru, C, Crane, B.R, Sudhamsu, J. 登録日 2009-07-16 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Relaxation dynamics of Pseudomonas aeruginosa Re(I)(CO)3(alpha-diimine)(HisX)+ (X = 83, 107, 109, 124, 126)Cu(II) azurins. J.Am.Chem.Soc., 131, 2009

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