6GB2
 
 | | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 39S ribosomal subunit. | | 分子名称: | 'Mitochondrial ribosomal protein L30, 'Mitochondrial ribosomal protein L55, 'Mitochondrial ribosomal protein L59, ... | | 著者 | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | | 登録日 | 2018-04-13 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Nature, 560, 2018
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7V5L
 | | Crystal structure of human bleomycin hydrolase | | 分子名称: | Bleomycin hydrolase | | 著者 | Chang, C.Y, Zheng, Y.Z, Huang, S.J, Wang, Y.L, Toh, S.I, Lin, E.C. | | 登録日 | 2021-08-17 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease.
Chembiochem, 23, 2022
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8CNK
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8CQC
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6BMM
 | | Structure of human DHHC20 palmitoyltransferase, space group P21 | | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,5S)-hexane-2,5-diol, PHOSPHATE ION, ... | | 著者 | Rana, M.S, Lee, C.-J, Banerjee, A. | | 登録日 | 2017-11-15 | | 公開日 | 2018-01-24 | | 最終更新日 | 2018-03-28 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Fatty acyl recognition and transfer by an integral membraneS-acyltransferase.
Science, 359, 2018
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6FAX
 | | Complex of Human CD40 Ectodomain with Lob 7.4 Fab | | 分子名称: | Lob 7.4 heavy chain, Lob 7.4 light chain, Tumor necrosis factor receptor superfamily member 5 | | 著者 | Orr, C.M, Tews, I, Pearson, A.R. | | 登録日 | 2017-12-18 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies.
Cancer Cell, 33, 2018
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6FB4
 | | human KIBRA C2 domain mutant C771A | | 分子名称: | GLYCEROL, PHOSPHATE ION, Protein KIBRA | | 著者 | Crennell, S.J, Posner, M.G, Bagby, S. | | 登録日 | 2017-12-18 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.415631 Å) | | 主引用文献 | Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain.
J. Biol. Chem., 293, 2018
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7CAT
 | | The NADPH binding site on beef liver catalase | | 分子名称: | CATALASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Murthy, M.R.N, Reid III, T.J, Sicignano, A, Tanaka, N, Fita, I, Rossmann, M.G. | | 登録日 | 1984-11-15 | | 公開日 | 1985-04-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The NADPH binding site on beef liver catalase.
Proc.Natl.Acad.Sci.USA, 82, 1985
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7YNH
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5LHG
 | | Structure of the KDM1A/CoREST complex with the inhibitor 4-methyl-N-[4-[[4-(1-methylpiperidin-4-yl)oxyphenoxy]methyl]phenyl]thieno[3,2-b]pyrrole-5-carboxamide | | 分子名称: | 4-methyl-N-[4-[[4-[(1-methyl-4-piperidyl)oxy]phenoxy]methyl]phenyl]thieno[3,2-b]pyrrole-5-carboxamide, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Cecatiello, V, Pasqualato, S. | | 登録日 | 2016-07-11 | | 公開日 | 2017-02-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | | 主引用文献 | Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.
J. Med. Chem., 60, 2017
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1FLS
 | | SOLUTION STRUCTURE OF THE CATALYTIC FRAGMENT OF HUMAN COLLAGENASE-3 (MMP-13) COMPLEXED WITH A HYDROXAMIC ACID INHIBITOR | | 分子名称: | CALCIUM ION, COLLAGENASE-3, N-HYDROXY-2-[(4-METHOXY-BENZENESULFONYL)-PYRIDIN-3-YLMETHYL-AMINO]-3-METHYL-BENZAMIDE, ... | | 著者 | Moy, F.J, Chanda, P.K, Chen, J.M, Cosmi, S, Edris, W, Levin, J.I, Powers, R. | | 登録日 | 2000-08-15 | | 公開日 | 2001-08-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution solution structure of the catalytic fragment of human collagenase-3 (MMP-13) complexed with a hydroxamic acid inhibitor.
J.Mol.Biol., 302, 2000
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2CEL
 | | ACTIVE-SITE MUTANT E212Q DETERMINED AT PH 6.0 WITH NO LIGAND BOUND IN THE ACTIVE SITE | | 分子名称: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION | | 著者 | Divne, C, Stahlberg, J, Jones, T.A. | | 登録日 | 1996-08-24 | | 公開日 | 1997-03-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Activity studies and crystal structures of catalytically deficient mutants of cellobiohydrolase I from Trichoderma reesei.
J.Mol.Biol., 264, 1996
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6CWM
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1JVQ
 | | Crystal structure at 2.6A of the ternary complex between antithrombin, a P14-P8 reactive loop peptide, and an exogenous tetrapeptide | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTITHROMBIN-III, ... | | 著者 | Zhou, A, Huntington, J.A, Lomas, D.A, Carrell, R.W, Stein, P.E. | | 登録日 | 2001-08-31 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | How small peptides block and reverse serpin polymerisation
J.Mol.Biol., 342, 2004
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2CBR
 | | CELLULAR RETINOIC ACID BINDING PROTEIN I IN COMPLEX WITH A RETINOBENZOIC ACID (AM80) | | 分子名称: | 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid, PROTEIN (CRABP-I) | | 著者 | Chaudhuri, B, Kleywegt, G.J, Bergfors, T, Jones, T.A. | | 登録日 | 1999-02-22 | | 公開日 | 1999-12-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids.
Acta Crystallogr.,Sect.D, 55, 1999
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7BMH
 | | Crystal structure of a light-driven proton pump LR (Mac) from Leptosphaeria maculans | | 分子名称: | EICOSANE, OLEIC ACID, Opsin | | 著者 | Kovalev, K, Zabelskii, D, Dmitrieva, N, Volkov, O, Shevchenko, V, Astashkin, R, Zinovev, E, Gordeliy, V. | | 登録日 | 2021-01-20 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-based insights into evolution of rhodopsins.
Commun Biol, 4, 2021
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1M16
 | | Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V). | | 分子名称: | FORMIC ACID, SULFATE ION, acidic fibroblast growth factor | | 著者 | Brych, S.R, Kim, J, Spielmann, G.L, Logan, T.M, Blaber, M. | | 登録日 | 2002-06-17 | | 公開日 | 2003-08-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Accommodation of a highly symmetric core within a symmetric protein superfold
Protein Sci., 12, 2003
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8RGG
 | | Structure of dynein-2 intermediate chain DYNC2I2 (WDR34) in complex with dynein-2 heavy chain DYNC2H1. | | 分子名称: | Cytoplasmic dynein 2 intermediate chain 1, Cytoplasmic dynein 2 intermediate chain 2, Dynein light chain 1, ... | | 著者 | Mukhopadhyay, A.G, Toropova, K, Daly, L, Wells, J, Vuolo, L, Mladenov, M, Seda, M, Jenkins, D, Stephens, D.J, Roberts, A.J. | | 登録日 | 2023-12-13 | | 公開日 | 2024-03-20 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structure and tethering mechanism of dynein-2 intermediate chains in intraflagellar transport.
Embo J., 43, 2024
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5OR7
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5NJT
 | | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Beckert, B, Abdelshahid, M, Schaefer, H, Steinchen, W, Arenz, S, Berninghausen, O, Beckmann, R, Bange, G, Turgay, K, Wilson, D.N. | | 登録日 | 2017-03-29 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization.
EMBO J., 36, 2017
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3K8T
 | | Structure of eukaryotic rnr large subunit R1 complexed with designed adp analog compound | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2'-deoxy-2'-(2-hydroxyethyl)adenosine 5'-(trihydrogen diphosphate), GLYCEROL, ... | | 著者 | Sun, D, Xu, H, Dealwis, C, Lee, R.E. | | 登録日 | 2009-10-14 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Based Design, Synthesis, and Evaluation of 2'-(2-Hydroxyethyl)-2'-deoxyadenosine and the 5'-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors
Chemmedchem, 4, 2009
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5LTO
 | | Ligand binding domain of Pseudomonas aeruginosa PAO1 amino acid chemoreceptors PctB in complex with L-Gln | | 分子名称: | GLUTAMINE, GLYCEROL, Methyl-accepting chemotaxis protein PctB, ... | | 著者 | Gavira, J.A, Rico-Jimenez, M, Conejero-Muriel, M, Krell, T. | | 登録日 | 2016-09-07 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.459 Å) | | 主引用文献 | How Bacterial Chemoreceptors Evolve Novel Ligand Specificities
Mbio, 2020
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5LT9
 | | Ligand binding domain of Pseudomonas aeruginosa PAO1 amino acid chemoreceptors PctB in complex with L-Arg | | 分子名称: | ARGININE, GLYCEROL, Methyl-accepting chemotaxis protein PctB, ... | | 著者 | Gavira, J.A, Rico-Jimenez, M, Ortega, A, Conejero-Muriel, M, Zhulin, I, Krell, T. | | 登録日 | 2016-09-06 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | How Bacterial Chemoreceptors Evolve Novel Ligand Specificities
Mbio, 2020
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7EDX
 | | p53-bound TFIID-based core PIC on HDM2 promoter | | 分子名称: | DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | | 登録日 | 2021-03-17 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EG7
 | | TFIID-based core PIC on SCP promoter | | 分子名称: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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