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2ONE
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BU of 2one by Molmil
ASYMMETRIC YEAST ENOLASE DIMER COMPLEXED WITH RESOLVED 2'-PHOSPHOGLYCERATE AND PHOSPHOENOLPYRUVATE
分子名称: 2-PHOSPHOGLYCERIC ACID, ENOLASE, LITHIUM ION, ...
著者Lebioda, L.
登録日1997-09-08
公開日1998-01-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of enolase: the crystal structure of asymmetric dimer enolase-2-phospho-D-glycerate/enolase-phosphoenolpyruvate at 2.0 A resolution.
Biochemistry, 36, 1997
1GVD
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BU of 1gvd by Molmil
CRYSTAL STRUCTURE OF C-MYB R2 V103L MUTANT
分子名称: AMMONIUM ION, MYB PROTO-ONCOGENE PROTEIN, SULFATE ION
著者Tahirov, T.H, Ogata, K.
登録日2002-02-08
公開日2003-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structure of C-Myb DNA-Binding Domain: Specific Na+ Binding and Correlation with NMR Structure
To be Published
1H9P
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BU of 1h9p by Molmil
Crystal Structure of Dioclea guianensis Seed Lectin
分子名称: CADMIUM ION, LECTIN ALPHA CHAIN, MANGANESE (II) ION
著者Romero, A, Wah, D.A, Gallego Del sol, F, Cavada, B.S, Ramos, M.V, Grangeiro, T.B, Sampaio, A.H, Calvete, J.J.
登録日2001-03-16
公開日2001-03-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Native and Cd/Cd-Substituted Dioclea Guianensis Seed Lectin. A Novel Manganese-Binding Site and Structural Basis of Dimer-Tetramer Association
J.Mol.Biol., 310, 2001
6H2L
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BU of 6h2l by Molmil
Receptor-binding domain of Proteus mirabilis Uroepithelial Cell Adhesin UcaD21-217
分子名称: Putative fimbrial adhesin, SULFATE ION
著者Wangshu, J, Knight, S.D.
登録日2018-07-13
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of two fimbrial adhesins, AtfE and UcaD, from the uropathogen Proteus mirabilis.
Acta Crystallogr D Struct Biol, 74, 2018
5NJ6
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BU of 5nj6 by Molmil
Crystal structure of a thermostabilised human protease-activated receptor-2 (PAR2) in ternary complex with Fab3949 and AZ7188 at 4.0 angstrom resolution
分子名称: Fab3949 H, Fab3949 L, Proteinase-activated receptor 2,Soluble cytochrome b562,Proteinase-activated receptor 2
著者Cheng, R.K.Y, Fiez-Vandal, C, Schlenker, O, Edman, K, Aggeler, B, Brown, D.G, Brown, G, Cooke, R.M, Dumelin, C.E, Dore, A.S, Geschwindner, S, Grebner, C, Hermansson, N.-O, Jazayeri, A, Johansson, P, Leong, L, Prihandoko, R, Rappas, M, Soutter, H, Snijder, A, Sundstrom, L, Tehan, B, Thornton, P, Troast, D, Wiggin, G, Zhukov, A, Marshall, F.H, Dekker, N.
登録日2017-03-28
公開日2017-05-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural insight into allosteric modulation of protease-activated receptor 2.
Nature, 545, 2017
3KEV
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BU of 3kev by Molmil
X-ray crystal structure of a DCUN1 domain-containing protein from Galdieria sulfuraria
分子名称: ACETATE ION, Galieria sulfuraria DCUN1 domain-containing protein, SULFATE ION
著者Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2009-10-26
公開日2009-12-01
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural architecture of Galdieria sulphuraria DCN1L.
Proteins, 79, 2011
6B5G
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BU of 6b5g by Molmil
ALDH1A2 liganded with NAD and (3-ethoxythiophen-2-yl){4-[4-nitro-3-(pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone (compound 6-118)
分子名称: (3-ethoxythiophen-2-yl){4-[4-nitro-3-(pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Retinal dehydrogenase 2
著者Chen, Y, Zhu, J.-Y, Schonbrunn, E.
登録日2017-09-29
公開日2018-01-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
1LYB
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BU of 1lyb by Molmil
CRYSTAL STRUCTURES OF NATIVE AND INHIBITED FORMS OF HUMAN CATHEPSIN D: IMPLICATIONS FOR LYSOSOMAL TARGETING AND DRUG DESIGN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATHEPSIN D, PEPSTATIN, ...
著者Baldwin, E.T, Bhat, T.N, Gulnik, S, Erickson, J.W.
登録日1993-04-22
公開日1994-01-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design.
Proc.Natl.Acad.Sci.USA, 90, 1993
5LSK
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BU of 5lsk by Molmil
CRYSTAL STRUCTURE OF THE HUMAN KINETOCHORE MIS12-CENP-C COMPLEX
分子名称: Centromere protein C, Kinetochore-associated protein DSN1 homolog, Kinetochore-associated protein NSL1 homolog, ...
著者Vetter, I.R, Petrovic, A, Keller, J, Liu, Y.
登録日2016-09-02
公開日2016-11-16
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.502 Å)
主引用文献Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
Cell, 167, 2016
7YC2
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BU of 7yc2 by Molmil
Crystal structure of auxiliary protein in complex with human protein
分子名称: ORF, Protein zyg-11 homolog B
著者Gao, X, Cui, S.
登録日2022-06-30
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献SARS-CoV-2 ORF10 hijacking ubiquitination machinery reveals potential unique drug targeting sites
Acta Pharm Sin B, 2024
1HCC
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BU of 1hcc by Molmil
THREE-DIMENSIONAL STRUCTURE OF A COMPLEMENT CONTROL PROTEIN MODULE IN SOLUTION
分子名称: 16TH COMPLEMENT CONTROL PROTEIN
著者Norman, D.G, Barlow, P.B, Campbell, I.D.C.
登録日1990-11-28
公開日1992-04-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of a complement control protein module in solution.
J.Mol.Biol., 219, 1991
5MKJ
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BU of 5mkj by Molmil
Crystal structure of the Retinoid X Receptor alpha in complex with synthetic honokiol derivative 9 and a fragment of the TIF2 co-activator.
分子名称: (~{E})-3-[4-oxidanyl-3-(5-prop-2-enyl-2-propoxy-phenyl)phenyl]prop-2-enoic acid, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP, Retinoic acid receptor RXR-alpha
著者Andrei, S.A, Brunsveld, L, Scheepstra, M, Ottmann, C.
登録日2016-12-05
公開日2017-11-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization.
ACS Chem Neurosci, 8, 2017
2END
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BU of 2end by Molmil
CRYSTAL STRUCTURE OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME FROM BACTERIOPHAGE T4: REFINEMENT AT 1.45 ANGSTROMS AND X-RAY ANALYSIS OF THE THREE ACTIVE SITE MUTANTS
分子名称: ENDONUCLEASE V
著者Vassylyev, D.G, Ariyoshi, M, Matsumoto, O, Katayanagi, K, Ohtsuka, E, Morikawa, K.
登録日1994-08-08
公開日1994-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
J.Mol.Biol., 249, 1995
6B5I
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BU of 6b5i by Molmil
ALDH1A2 liganded with 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide (compound CM121)
分子名称: 1-(4-cyanophenyl)-N-(3-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-1H-pyrazole-4-carboxamide, Retinal dehydrogenase 2
著者Chen, Y, Zhu, J.-Y, Schonbrunn, E.
登録日2017-09-29
公開日2018-01-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors.
ACS Chem. Biol., 13, 2018
8H5B
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BU of 8h5b by Molmil
The cryo-EM structure of nuclear transport receptor Kap114p complex with yeast TATA-box binding protein
分子名称: Importin subunit beta-5, TATA-box-binding protein
著者Hsia, K.C, Liao, C.C, Wang, C.H, Wu, Y.M.
登録日2022-10-12
公開日2023-09-20
実験手法ELECTRON MICROSCOPY (4.03 Å)
主引用文献Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein.
Nat Commun, 14, 2023
5NN6
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BU of 5nn6 by Molmil
Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with N-hydroxyethyl-1-deoxynojirimycin
分子名称: (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Roig-Zamboni, V, Cobucci-Ponzano, B, Iacono, R, Ferrara, M.C, Germany, S, Parenti, G, Bourne, Y, Moracci, M.
登録日2017-04-08
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease.
Nat Commun, 8, 2017
5NN4
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BU of 5nn4 by Molmil
Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with N-acetyl-cysteine
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Roig-Zamboni, V, Cobucci-Ponzano, B, Iacono, R, Ferrara, M.C, Germany, S, Parenti, G, Bourne, Y, Moracci, M.
登録日2017-04-08
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease.
Nat Commun, 8, 2017
7WJU
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BU of 7wju by Molmil
Cryo-EM structure of the AsCas12f1-sgRNAv1-dsDNA ternary complex
分子名称: Non-target strand, OrfB_Zn_ribbon domain-containing protein, Target strand, ...
著者Wu, Z, Liu, D, Shen, H, Ji, Q.
登録日2022-01-07
公開日2023-01-18
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Structure-directed functional evolution of the miniature CRISPR-AsCas12f1 system
To Be Published
1HE1
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BU of 1he1 by Molmil
Crystal structure of the complex between the GAP domain of the Pseudomonas aeruginosa ExoS toxin and human Rac
分子名称: ALUMINUM FLUORIDE, EXOENZYME S, GUANOSINE-5'-DIPHOSPHATE, ...
著者Wurtele, M, Wolf, E, Pederson, K.J, Buchwald, G, Ahmadian, M.R, Barbieri, J.T, Wittinghofer, A.
登録日2000-11-18
公開日2001-01-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献How the Pseudomonas Aeruginosa Exos Toxin Downregulates Rac
Nat.Struct.Biol., 8, 2001
5NKX
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BU of 5nkx by Molmil
HRSV M2-1 core domain, P3221 crystal form
分子名称: M2-1
著者Almeida Hernandez, Y, Josts, I, Molina, I.G, de Pray-Gay, G, Tidow, H.
登録日2017-04-03
公開日2018-01-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.00008678 Å)
主引用文献Structure and stability of the Human respiratory syncytial virus M2-1RNA-binding core domain reveals a compact and cooperative folding unit.
Acta Crystallogr F Struct Biol Commun, 74, 2018
2CI2
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BU of 2ci2 by Molmil
CRYSTAL AND MOLECULAR STRUCTURE OF THE SERINE PROTEINASE INHIBITOR CI-2 FROM BARLEY SEEDS
分子名称: CHYMOTRYPSIN INHIBITOR 2
著者Mcphalen, C.A, James, M.N.G.
登録日1988-09-05
公開日1988-09-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds.
Biochemistry, 26, 1987
3KDF
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BU of 3kdf by Molmil
X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free Expression
分子名称: 1,2-ETHANEDIOL, Replication protein A 14 kDa subunit, Replication protein A 32 kDa subunit
著者Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Fox, B.G, Makino, S.-I, Center for Eukaryotic Structural Genomics (CESG)
登録日2009-10-22
公開日2009-12-01
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (1.975 Å)
主引用文献X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free Expression
To be Published
6BML
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BU of 6bml by Molmil
Structure of human DHHC20 palmitoyltransferase, irreversibly inhibited by 2-bromopalmitate
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, PALMITIC ACID, PHOSPHATE ION, ...
著者Rana, M.S, Lee, C.-J, Banerjee, A.
登録日2017-11-15
公開日2018-01-24
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Fatty acyl recognition and transfer by an integral membraneS-acyltransferase.
Science, 359, 2018
3NIB
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BU of 3nib by Molmil
Teg14 Apo
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Teg14
著者Bick, M.J, Banik, J.J, Darst, S.A, Brady, S.F.
登録日2010-06-15
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The 2.7 A resolution structure of the glycopeptide sulfotransferase Teg14
Acta Crystallogr.,Sect.D, 66, 2010
2CBS
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BU of 2cbs by Molmil
CELLULAR RETINOIC ACID BINDING PROTEIN II IN COMPLEX WITH A SYNTHETIC RETINOIC ACID (RO-13 6307)
分子名称: 3-METHYL-7-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL) -OCTA-2,4,6-TRIENOIC ACID, PROTEIN (CRABP-II)
著者Chaudhuri, B, Kleywegt, G.J, Bergfors, T, Jones, T.A.
登録日1999-02-22
公開日1999-12-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids.
Acta Crystallogr.,Sect.D, 55, 1999

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