PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3FMD	Crystal Structure of Human Haspin with an Isoquinoline ligand 分子名称: 1,2-ETHANEDIOL, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, NICKEL (II) ION, ... 著者 Filippakopoulos, P, Eswaran, J, Keates, T, Burgess-Brown, N, Fedorov, O, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2008-12-21 公開日 2008-12-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Human Haspin with an Isoquinoline ligand To be Published
3I2E	Crystal structure of human dimethylarginine dymethylaminohydrolase-1 (DDAH-1) 分子名称: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 著者 Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Robertus, J.D, Fast, W. 登録日 2009-06-29 公開日 2009-08-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide. Biochemistry, 48, 2009
3I2O	Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate and methylated trinucleotide T-meA-T 分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB, DNA (5'-D(P*TP*(MA7)P*T)-3'), ... 著者 Yu, B, Hunt, J.F. 登録日 2009-06-29 公開日 2009-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB. Proc.Natl.Acad.Sci.USA, 106, 2009
3I2Y	Proteinase K by Classical hanging drop Method before high X-Ray dose on ID14-2 Beamline at ESRF 分子名称: CALCIUM ION, Proteinase K 著者 Pechkova, E, Tripathi, S.K, Ravelli, R, McSweeney, S, Nicolini, C. 登録日 2009-06-30 公開日 2010-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (0.995 Å) 主引用文献 Atomic structure and radiation resistance of Langmuir-Blodgett protein crystals To be Published
3HRD	Crystal structure of nicotinate dehydrogenase 分子名称: CALCIUM ION, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Wagener, N, Pierik, A.J, Hille, R, Dobbek, H. 登録日 2009-06-09 公開日 2009-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Mo-Se active site of nicotinate dehydrogenase Proc.Natl.Acad.Sci.USA, 106, 2009
3HSS	A higher resolution structure of Rv0554 from Mycobacterium tuberculosis complexed with malonic acid 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... 著者 Johnston, J.M, Baker, E.N. 登録日 2009-06-10 公開日 2010-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis. Acta Crystallogr.,Sect.D, 66, 2010
3HT0	Crystal structure of E. coli HPPK(F123A) in complex with MgAMPCPP 分子名称: CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, HPPK, ... 著者 Blaszczyk, J, Li, Y, Yan, H, Ji, X. 登録日 2009-06-11 公開日 2010-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published
3HT7	2-ethylphenol in complex with T4 lysozyme L99A/M102Q 分子名称: 2-ethylphenol, BETA-MERCAPTOETHANOL, Lysozyme, ... 著者 Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K. 登録日 2009-06-11 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site. J.Mol.Biol., 394, 2009
3HTF	4-chloro-1h-pyrazole in complex with T4 lysozyme L99A/M102Q 分子名称: 4-chloro-1H-pyrazole, BETA-MERCAPTOETHANOL, Lysozyme, ... 著者 Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K. 登録日 2009-06-11 公開日 2009-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site. J.Mol.Biol., 394, 2009
3HTN	Crystal structure of a putative dna binding protein (bt_1116) from bacteroides thetaiotaomicron vpi-5482 at 1.50 A resolution 分子名称: FE (III) ION, NICKEL (II) ION, PENTAETHYLENE GLYCOL, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-06-12 公開日 2009-06-30 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Putative DNA binding protein (NP_810029.1) from Bacteroides thetaiotaomicron VPI-5482 at 1.50 A resolution To be Published
3HWS	Crystal structure of nucleotide-bound hexameric ClpX 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit clpX, MAGNESIUM ION, ... 著者 Glynn, S.E, Martin, A, Baker, T.A, Sauer, R.T. 登録日 2009-06-18 公開日 2009-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell(Cambridge,Mass.), 139, 2009
3I56	Co-crystal structure of Triacetyloleandomcyin Bound to the Large Ribosomal Subunit 分子名称: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... 著者 Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B. 登録日 2009-07-03 公開日 2010-03-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui. Antimicrob.Agents Chemother., 53, 2009
3HMW	Crystal structure of ustekinumab FAB 分子名称: CADMIUM ION, USTEKINUMAB FAB HEAVY CHAIN, USTEKINUMAB FAB LIGHT CHAIN 著者 Luo, J. 登録日 2009-05-29 公開日 2010-06-09 最終更新日 2015-07-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab. J.Mol.Biol., 402, 2010
3HYD	LVEALYL peptide derived from human insulin chain B, residues 11-17 分子名称: Insulin 著者 Ivanova, M.I, Sawaya, M.R, Eisenberg, D. 登録日 2009-06-22 公開日 2009-10-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Molecular basis for insulin fibril assembly. Proc.Natl.Acad.Sci.USA, 106, 2009
3HN7	Crystal structure of a murein peptide ligase mpl (psyc_0032) from psychrobacter arcticus 273-4 at 1.65 A resolution 分子名称: UDP-N-acetylmuramate-L-alanine ligase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-05-29 公開日 2009-06-16 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and function of the first full-length murein Peptide ligase (mpl) cell wall recycling protein. Plos One, 6, 2011
3HNJ	Crystal structure of the Zn-induced tetramer of the engineered cyt cb562 variant RIDC-2 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Soluble cytochrome b562, ZINC ION 著者 Salgado, E.N, Lewis, R.A, Brodin, J, Tezcan, F.A. 登録日 2009-05-31 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Metal templated design of protein interfaces. Proc.Natl.Acad.Sci.USA, 107, 2010
3HZ2	Crystal structure of a betagamma-crystallin from an Archaea 分子名称: Beta/gama crystallin family protein, CALCIUM ION 著者 Aravind, P, Sankaranarayanan, R. 登録日 2009-06-23 公開日 2009-12-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 The betagamma-crystallin superfamily contains a universal motif for binding calcium Biochemistry, 48, 2009
3HNY	Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor 分子名称: Coagulation factor VIII 著者 Liu, Z, Yuan, C. 登録日 2009-06-01 公開日 2010-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. J.Biol.Chem., 285, 2010
3HZB	Crystal structure of a betagamma-crystallin domain from Flavobacterium johnsoniae 分子名称: CALCIUM ION, Carbohydrate binding protein 著者 Aravind, P, Sankaranarayanan, R. 登録日 2009-06-23 公開日 2009-12-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 The betagamma-crystallin superfamily contains a universal motif for binding calcium Biochemistry, 48, 2009
3HZY	Crystal structure of S73-2 antibody in complex with antigen Kdo(2.4)Kdo(2.4)Kdo 分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, MAGNESIUM ION, S73-2 Fab (IgG1k) heavy chain, ... 著者 Brooks, C.L, Muller-Loennies, S, Borisova, S.N, Brade, L, Kosma, P, Hirama, T, MacKenzie, C.R, Brade, H, Evans, S.V. 登録日 2009-06-24 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition Biochemistry, 49, 2010
3HOJ	Crystal Structure of a Novel Engineered Retroaldolase: RA-22 分子名称: RETROALDOLASE-22 著者 Stoddard, B.L, Doyle, L.A. 登録日 2009-06-02 公開日 2009-08-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 De Novo Computational Design of Retro-Aldol Enzymes Science, 319, 2008
3I0E	Crystal structure of GTB C80S/C196S + H-antigen 分子名称: ABO glycosyltransferase, alpha-L-fucopyranose-(1-2)-hexyl beta-D-galactopyranoside 著者 Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. 登録日 2009-06-25 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402, 2010
3I0L	Crystal structure of GTB C80S/C196S/C209S + DA + UDP-Gal 分子名称: ABO glycosyltransferase, URIDINE-5'-DIPHOSPHATE, alpha-L-fucopyranose-(1-2)-hexyl beta-D-galactopyranoside, ... 著者 Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. 登録日 2009-06-25 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402, 2010
3I0X	Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing adenine opposite to 8-oxoG 分子名称: 5'-D(*AP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*AP*TP*GP*GP*A)-3', 8-oxoguanine-DNA-glycosylase, ... 著者 Faucher, F, Doublie, S. 登録日 2009-06-25 公開日 2009-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase. Dna Repair, 8, 2009
3HQW	Discovery of novel inhibitors of PDE10A 分子名称: 4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole, MAGNESIUM ION, ZINC ION, ... 著者 Pandit, J, Marr, E.S. 登録日 2009-06-08 公開日 2009-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia J.Med.Chem., 52, 2009

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