3FMD
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![BU of 3fmd by Molmil](/molmil-images/mine/3fmd) | Crystal Structure of Human Haspin with an Isoquinoline ligand | 分子名称: | 1,2-ETHANEDIOL, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, NICKEL (II) ION, ... | 著者 | Filippakopoulos, P, Eswaran, J, Keates, T, Burgess-Brown, N, Fedorov, O, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2008-12-21 | 公開日 | 2008-12-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Human Haspin with an Isoquinoline ligand To be Published
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3I2E
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![BU of 3i2e by Molmil](/molmil-images/mine/3i2e) | Crystal structure of human dimethylarginine dymethylaminohydrolase-1 (DDAH-1) | 分子名称: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 著者 | Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Robertus, J.D, Fast, W. | 登録日 | 2009-06-29 | 公開日 | 2009-08-25 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide. Biochemistry, 48, 2009
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3I2O
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3I2Y
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![BU of 3i2y by Molmil](/molmil-images/mine/3i2y) | Proteinase K by Classical hanging drop Method before high X-Ray dose on ID14-2 Beamline at ESRF | 分子名称: | CALCIUM ION, Proteinase K | 著者 | Pechkova, E, Tripathi, S.K, Ravelli, R, McSweeney, S, Nicolini, C. | 登録日 | 2009-06-30 | 公開日 | 2010-06-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (0.995 Å) | 主引用文献 | Atomic structure and radiation resistance of Langmuir-Blodgett protein crystals To be Published
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3HRD
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![BU of 3hrd by Molmil](/molmil-images/mine/3hrd) | Crystal structure of nicotinate dehydrogenase | 分子名称: | CALCIUM ION, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Wagener, N, Pierik, A.J, Hille, R, Dobbek, H. | 登録日 | 2009-06-09 | 公開日 | 2009-06-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Mo-Se active site of nicotinate dehydrogenase Proc.Natl.Acad.Sci.USA, 106, 2009
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3HSS
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![BU of 3hss by Molmil](/molmil-images/mine/3hss) | A higher resolution structure of Rv0554 from Mycobacterium tuberculosis complexed with malonic acid | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | 著者 | Johnston, J.M, Baker, E.N. | 登録日 | 2009-06-10 | 公開日 | 2010-05-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis. Acta Crystallogr.,Sect.D, 66, 2010
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3HT0
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![BU of 3ht0 by Molmil](/molmil-images/mine/3ht0) | Crystal structure of E. coli HPPK(F123A) in complex with MgAMPCPP | 分子名称: | CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, HPPK, ... | 著者 | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | 登録日 | 2009-06-11 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Pterin-binding site mutation Y53A, N55A or F123A and activity of E. coli HPPK To be Published
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3HT7
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![BU of 3ht7 by Molmil](/molmil-images/mine/3ht7) | 2-ethylphenol in complex with T4 lysozyme L99A/M102Q | 分子名称: | 2-ethylphenol, BETA-MERCAPTOETHANOL, Lysozyme, ... | 著者 | Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K. | 登録日 | 2009-06-11 | 公開日 | 2009-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site. J.Mol.Biol., 394, 2009
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3HTF
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![BU of 3htf by Molmil](/molmil-images/mine/3htf) | 4-chloro-1h-pyrazole in complex with T4 lysozyme L99A/M102Q | 分子名称: | 4-chloro-1H-pyrazole, BETA-MERCAPTOETHANOL, Lysozyme, ... | 著者 | Boyce, S.E, Mobley, D.L, Rocklin, G.J, Graves, A.P, Dill, K.A, Shoichet, B.K. | 登録日 | 2009-06-11 | 公開日 | 2009-11-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Predicting ligand binding affinity with alchemical free energy methods in a polar model binding site. J.Mol.Biol., 394, 2009
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3HTN
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3HWS
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![BU of 3hws by Molmil](/molmil-images/mine/3hws) | Crystal structure of nucleotide-bound hexameric ClpX | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit clpX, MAGNESIUM ION, ... | 著者 | Glynn, S.E, Martin, A, Baker, T.A, Sauer, R.T. | 登録日 | 2009-06-18 | 公開日 | 2009-11-24 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine. Cell(Cambridge,Mass.), 139, 2009
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3I56
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![BU of 3i56 by Molmil](/molmil-images/mine/3i56) | Co-crystal structure of Triacetyloleandomcyin Bound to the Large Ribosomal Subunit | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... | 著者 | Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B. | 登録日 | 2009-07-03 | 公開日 | 2010-03-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui. Antimicrob.Agents Chemother., 53, 2009
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3HMW
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![BU of 3hmw by Molmil](/molmil-images/mine/3hmw) | Crystal structure of ustekinumab FAB | 分子名称: | CADMIUM ION, USTEKINUMAB FAB HEAVY CHAIN, USTEKINUMAB FAB LIGHT CHAIN | 著者 | Luo, J. | 登録日 | 2009-05-29 | 公開日 | 2010-06-09 | 最終更新日 | 2015-07-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab. J.Mol.Biol., 402, 2010
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3HYD
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3HN7
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3HNJ
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![BU of 3hnj by Molmil](/molmil-images/mine/3hnj) | Crystal structure of the Zn-induced tetramer of the engineered cyt cb562 variant RIDC-2 | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Soluble cytochrome b562, ZINC ION | 著者 | Salgado, E.N, Lewis, R.A, Brodin, J, Tezcan, F.A. | 登録日 | 2009-05-31 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Metal templated design of protein interfaces. Proc.Natl.Acad.Sci.USA, 107, 2010
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3HZ2
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3HNY
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3HZB
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3HZY
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![BU of 3hzy by Molmil](/molmil-images/mine/3hzy) | Crystal structure of S73-2 antibody in complex with antigen Kdo(2.4)Kdo(2.4)Kdo | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, MAGNESIUM ION, S73-2 Fab (IgG1k) heavy chain, ... | 著者 | Brooks, C.L, Muller-Loennies, S, Borisova, S.N, Brade, L, Kosma, P, Hirama, T, MacKenzie, C.R, Brade, H, Evans, S.V. | 登録日 | 2009-06-24 | 公開日 | 2010-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Antibodies raised against chlamydial lipopolysaccharide antigens reveal convergence in germline gene usage and differential epitope recognition Biochemistry, 49, 2010
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3HOJ
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3I0E
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![BU of 3i0e by Molmil](/molmil-images/mine/3i0e) | Crystal structure of GTB C80S/C196S + H-antigen | 分子名称: | ABO glycosyltransferase, alpha-L-fucopyranose-(1-2)-hexyl beta-D-galactopyranoside | 著者 | Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. | 登録日 | 2009-06-25 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402, 2010
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3I0L
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![BU of 3i0l by Molmil](/molmil-images/mine/3i0l) | Crystal structure of GTB C80S/C196S/C209S + DA + UDP-Gal | 分子名称: | ABO glycosyltransferase, URIDINE-5'-DIPHOSPHATE, alpha-L-fucopyranose-(1-2)-hexyl beta-D-galactopyranoside, ... | 著者 | Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. | 登録日 | 2009-06-25 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding J.Mol.Biol., 402, 2010
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3I0X
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3HQW
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![BU of 3hqw by Molmil](/molmil-images/mine/3hqw) | Discovery of novel inhibitors of PDE10A | 分子名称: | 4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole, MAGNESIUM ION, ZINC ION, ... | 著者 | Pandit, J, Marr, E.S. | 登録日 | 2009-06-08 | 公開日 | 2009-08-04 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia J.Med.Chem., 52, 2009
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