PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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6HZD	X-ray structure of furin in complex with the cyclic inhibitor c[glutaryl-Arg-Arg-Arg-Lys]-Arg-4-Amba 分子名称: ARG-ARG-ARG-LYS-ARG-00S, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O. 登録日 2018-10-23 公開日 2019-02-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin. Chemmedchem, 14, 2019
8ORP	Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose 分子名称: 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... 著者 Aghajari, N, Haser, R. 登録日 2023-04-16 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase. Molecules, 28, 2023
8BBX	Structure of prolyl endoprotease from Aspergillus niger CBS 109712 in space group C222(1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoprotease endo-Pro, TETRAETHYLENE GLYCOL, ... 著者 Pijning, T, Vujicic-Zagar, A, Van der Laan, J.M, De Jong, R.M, Dijkstra, B.W. 登録日 2022-10-14 公開日 2023-12-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and time-resolved mechanistic investigations of protein hydrolysis by the acidic proline-specific endoprotease from Aspergillus niger. Protein Sci., 33, 2024
1QTE	CRYSTAL STRUCTURE OF THE 70 KDA SOLUBLE LYTIC TRANSGLYCOSYLASE SLT70 FROM ESCHERICHIA COLI AT 1.90 A RESOLUTION IN COMPLEX WITH A 1,6-ANHYDROMUROTRIPEPTIDE 分子名称: 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 van Asselt, E.J, Thunnissen, A.-M.W.H, Dijkstra, B.W. 登録日 1999-06-27 公開日 1999-08-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High resolution crystal structures of the Escherichia coli lytic transglycosylase Slt70 and its complex with a peptidoglycan fragment. J.Mol.Biol., 291, 1999
8BW8	Crystal structure of the dCNK-SAM-CRIC-PDZ/dHYP-SAM complex 分子名称: Connector enhancer of KSR protein CNK, GLYCEROL, Protein aveugle 著者 Maisonneuve, P, Kurinov, I, Sicheri, F. 登録日 2022-12-06 公開日 2024-02-21 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction. Nat.Struct.Mol.Biol., 31, 2024
8BHV	DNA-PK XLF mediated dimer bound to PAXX 分子名称: DNA (24-MER), DNA (26-MER), DNA (27-MER), ... 著者 Hardwick, S.W, Chaplin, A.K. 登録日 2022-11-01 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.51 Å) 主引用文献 PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8JB7	Crystal structure of CMY-185 分子名称: Beta-lactamase, SULFATE ION 著者 Kawai, A, Doi, Y. 登録日 2023-05-08 公開日 2023-12-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185. Mbio, 15, 2024
8JBC	Crystal Structure of the Csm6 K137A mutant from Thermus thermophilus HB8 in its apo form 分子名称: CRISPR system endoribonuclease Csm6, NICKEL (II) ION 著者 Lin, Z, Du, L. 登録日 2023-05-08 公開日 2023-12-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate. Embo J., 43, 2024
7ADH	THREE-DIMENSIONAL STRUCTURE OF ISONICOTINIMIDYLATED LIVER ALCOHOL DEHYDROGENASE 分子名称: ISONICOTINAMIDINE, ISONICOTINIMIDYLATED LIVER ALCOHOL DEHYDROGENASE, ZINC ION 著者 Plapp, B, Eklund, H. 登録日 1984-01-16 公開日 1984-07-18 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Three-dimensional structure of isonicotinimidylated liver alcohol dehydrogenase. J.Biol.Chem., 258, 1983
8JBB	Crystal Structure of the Csm6 from Thermus thermophilus HB8 in complex with A2>p 分子名称: CRISPR system endoribonuclease Csm6, RNA (5'-R(*AP*(A23))-3') 著者 Lin, Z, Du, L. 登録日 2023-05-08 公開日 2023-12-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate. Embo J., 43, 2024
8BHY	DNA-PK Ku80 mediated dimer bound to PAXX and XLF 分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ... 著者 Hardwick, S.W, Chaplin, A.K. 登録日 2022-11-01 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (5.33 Å) 主引用文献 PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8BH3	DNA-PK Ku80 mediated dimer bound to PAXX 分子名称: DNA (25-MER), DNA (26-MER), DNA (27-MER), ... 著者 Hardwick, S.W, Chaplin, A.K. 登録日 2022-10-28 公開日 2023-06-07 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.55 Å) 主引用文献 PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Sci Adv, 9, 2023
8JB8	Crystal structure of CMY-185 complex with ceftazidime 分子名称: ACYLATED CEFTAZIDIME, Beta-lactamase 著者 Kawai, A, Doi, Y. 登録日 2023-05-08 公開日 2023-12-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185. Mbio, 15, 2024
6HZC	X-ray structure of furin in complex with the cyclic inhibitor c[glutaryl-BVK-Lys-Arg-Arg-Tle-Lys]-4-Amba 分子名称: 2-[4-(aminomethyl)phenyl]ethanoic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O. 登録日 2018-10-23 公開日 2019-02-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin. Chemmedchem, 14, 2019
7PU1	High resolution X-ray structure of Thermoascus aurantiacus LPMO 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, COPPER (II) ION, ... 著者 Banerjee, S, Frandsen, K.E.H, Singh, R.K, Bjerrum, M.J, Lo Leggio, L. 登録日 2021-09-28 公開日 2022-03-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Protonation State of an Important Histidine from High Resolution Structures of Lytic Polysaccharide Monooxygenases. Biomolecules, 12, 2022
3AT1	CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH 分子名称: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ... 著者 Gouaux, J.E, Lipscomb, W.N. 登録日 1989-09-22 公開日 1990-10-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH. Biochemistry, 29, 1990
6HZB	X-ray structure of furin in complex with the cyclic inhibitor c[glutaryl-Arg-Arg-Lys]-Lys-4-Amba 分子名称: ARG-ARG-LYS-LYS-00S, CALCIUM ION, CHLORIDE ION, ... 著者 Dahms, S.O. 登録日 2018-10-23 公開日 2019-02-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin. Chemmedchem, 14, 2019
8C7Z	Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2308 分子名称: 1,2-ETHANEDIOL, 9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,6-dihydro-[1]benzoxepino[5,4-c]pyridine, AMMONIUM ION, ... 著者 Cros, J, Williams, E.P, Sweeney, M.N, Smil, D, Gonzalez-Alvarez, H, Al-awar, R, Bullock, A.N. 登録日 2023-01-18 公開日 2023-02-01 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Discovery of Conformationally Constrained ALK2 Inhibitors. J.Med.Chem., 67, 2024
8C7W	Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound M4K2304 分子名称: 1,2-ETHANEDIOL, 6-methyl-9-piperazin-1-yl-4-(3,4,5-trimethoxyphenyl)-5,7-dihydropyrido[4,3-d][2]benzazepine, Activin receptor type I, ... 著者 Cros, J, Williams, E.P, Sweeney, M.N, Smil, D, Gonzalez-Alvarez, H, Al-awar, R, Bullock, A.N. 登録日 2023-01-17 公開日 2023-02-08 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Discovery of Conformationally Constrained ALK2 Inhibitors. J.Med.Chem., 67, 2024
8C3F	Double mutant I(L177)H/F(M197)H structure of Photosynthetic Reaction Center From Cereibacter sphaeroides strain RV 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Gabdulkhakov, A.G, Selikhanov, G.K, Fufina, T.Y, Vasilieva, L.G. 登録日 2022-12-23 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Properties and Crystal Structure of the Cereibacter sphaeroides Photosynthetic Reaction Center with Double Amino Acid Substitution I(L177)H + F(M197)H. Membranes (Basel), 13, 2023
8OU1	Crystal structure of the SPOC domain of mouse SPOCD1 分子名称: CITRATE ANION, SPOC domain-containing protein 1 著者 Heep, M, Cook, A.G, O'Carroll, D. 登録日 2023-04-21 公開日 2024-02-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line. Mol.Cell, 84, 2024
8CD8	Ulilysin - C269A with AEBSF complex 分子名称: 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE, CALCIUM ION, GLY-SER-SER, ... 著者 Rodriguez-Banqueri, A, Eckhard, U, Gomis-Ruth, F.X. 登録日 2023-01-30 公開日 2023-03-22 最終更新日 2023-03-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural insights into latency of the metallopeptidase ulilysin (lysargiNase) and its unexpected inhibition by a sulfonyl-fluoride inhibitor of serine peptidases. Dalton Trans, 52, 2023
8CDB	Proulilysin E229A structure 分子名称: CALCIUM ION, Ulilysin, ZINC ION 著者 Rodriguez-Banqueri, A, Eckhard, U, Gomis-Ruth, F.X. 登録日 2023-01-30 公開日 2023-03-22 最終更新日 2023-03-29 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structural insights into latency of the metallopeptidase ulilysin (lysargiNase) and its unexpected inhibition by a sulfonyl-fluoride inhibitor of serine peptidases. Dalton Trans, 52, 2023
8EUY	Ytm1 associated nascent 60S ribosome (-fkbp39) State 1A 分子名称: 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... 著者 Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. 登録日 2022-10-19 公開日 2022-11-30 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
8ESQ	Ytm1 associated nascent 60S ribosome State 2 分子名称: 25S rRNA (cytosine-C(5))-methyltransferase nop2, 60S ribosomal protein L13, 60S ribosomal protein L14, ... 著者 Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. 登録日 2022-10-14 公開日 2022-11-30 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022

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