4RY2
 
 | |
4MYH
 | |
4MRP
 | | Structure of a bacterial Atm1-family ABC transporter | | 分子名称: | ABC transporter related protein, GLUTATHIONE, LAURYL DIMETHYLAMINE-N-OXIDE, ... | | 著者 | Lee, J.Y, Yang, J.G, Zhitnitsky, D, Lewinson, O, Rees, D.C. | | 登録日 | 2013-09-17 | | 公開日 | 2014-03-19 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for heavy metal detoxification by an Atm1-type ABC exporter.
Science, 343, 2014
|
|
4MRS
 | | Structure of a bacterial Atm1-family ABC transporter | | 分子名称: | ABC transporter related protein, LAURYL DIMETHYLAMINE-N-OXIDE, OXIDIZED GLUTATHIONE DISULFIDE, ... | | 著者 | Lee, J.Y, Yang, J.G, Zhitnitsky, D, Lewinson, O, Rees, D.C. | | 登録日 | 2013-09-17 | | 公開日 | 2014-03-19 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis for heavy metal detoxification by an Atm1-type ABC exporter.
Science, 343, 2014
|
|
4MRR
 | | Structure of a bacterial Atm1-family ABC transporter | | 分子名称: | ABC transporter related protein, LAURYL DIMETHYLAMINE-N-OXIDE, PHOSPHATE ION, ... | | 著者 | Lee, J.Y, Yang, J.G, Zhitnitsky, D, Lewinson, O, Rees, D.C. | | 登録日 | 2013-09-17 | | 公開日 | 2014-03-19 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Structural basis for heavy metal detoxification by an Atm1-type ABC exporter.
Science, 343, 2014
|
|
7O9W
 | | Encequidar-bound human P-glycoprotein in complex with UIC2-Fab | | 分子名称: | Multidrug resistance protein 1, UIC2 Fab-fragment heavy chain, UIC2 Fab-fragment light chain, ... | | 著者 | Nosol, K, Locher, K.P. | | 登録日 | 2021-04-17 | | 公開日 | 2022-01-12 | | 最終更新日 | 2022-01-26 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Discovery and Characterization of Potent Dual P-Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations.
J.Med.Chem., 65, 2022
|
|
7BCW
 | | Structure of MsbA in Salipro with ADP vanadate | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-DIPHOSPHATE, ATP-dependent lipid A-core flippase, ... | | 著者 | Traore, D.A.K, Tidow, H. | | 登録日 | 2020-12-21 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of MsbA in saposin-lipid nanoparticles (Salipro) provides insights into nucleotide coordination.
Febs J., 289, 2022
|
|
7BG4
 | | Multidrug resistance transporter BmrA mutant E504A bound with ATP, Mg, and Rhodamine 6G solved by Cryo-EM | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding/permease protein BmrA, ... | | 著者 | Wiseman, B, Chaptal, V, Zampieri, V, Magnard, S, Hogbom, M, Falson, P. | | 登録日 | 2021-01-05 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
|
|
7OCY
 | | Enterococcus faecalis EfrCD in complex with a nanobody | | 分子名称: | ABC transporter ATP-binding protein, Nanobody | | 著者 | Ehrenbolger, K, Hutter, C.A.J, Meier, G, Seeger, M.A, Barandun, J. | | 登録日 | 2021-04-28 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | | 主引用文献 | Deep mutational scan of a drug efflux pump reveals its structure-function landscape.
Nat.Chem.Biol., 19, 2023
|
|
7OTI
 | | Structure of ABCB1/P-glycoprotein in apo state | | 分子名称: | Multidrug resistance protein 1A | | 著者 | Ford, R.C, Barbieri, A, Thonghin, N, Shafi, T, Prince, S.M, Collins, R.F. | | 登録日 | 2021-06-10 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor.
Membranes (Basel), 11, 2021
|
|
7OTG
 | | Structure of ABCB1/P-glycoprotein in the presence of the CFTR potentiator ivacaftor | | 分子名称: | Multidrug resistance protein 1A, N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide | | 著者 | Ford, R.C, Barbieri, A, Thonghin, N, Shafi, T, Prince, S.M, Collins, R.F. | | 登録日 | 2021-06-10 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor.
Membranes (Basel), 11, 2021
|
|
7OW8
 | | CryoEM structure of the ABC transporter BmrA E504A mutant in complex with ATP-Mg | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | | 著者 | Gobet, A, Schoehn, G, Falson, P, Chaptal, V. | | 登録日 | 2021-06-17 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.
Sci Adv, 8, 2022
|
|
7PSL
 | |
7PSM
 | |
7PSN
 | |
7PH3
 | | AMP-PNP bound nanodisc reconstituted MsbA with nanobodies, spin-labeled at position A60C | | 分子名称: | (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ATP-dependent lipid A-core flippase, ... | | 著者 | Parey, K, Januliene, D, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A. | | 登録日 | 2021-08-16 | | 公開日 | 2022-08-24 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells.
Sci Adv, 8, 2022
|
|
7D7N
 | | Cryo-EM structure of human ABCB6 transporter | | 分子名称: | ATP-binding cassette sub-family B member 6, mitochondrial | | 著者 | Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C. | | 登録日 | 2020-10-05 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | | 主引用文献 | Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
|
|
7PH7
 | | Nanodisc reconstituted MsbA in complex with nanobodies, spin-labeled at position T68C | | 分子名称: | (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{S},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,5-bis(oxidanyl)oxan-2-yl]oxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-4-[(3~{R})-3-nonanoyloxytetradecanoyl]oxy-5-[[(3~{R})-3-octanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{S},5~{S},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanylnonanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-oxan-2-yl]methoxy]-5-oxidanyl-oxane-2-carboxylic acid, ATP-binding transport protein multicopy suppressor of htrB, ... | | 著者 | Parey, K, Januliene, D, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A. | | 登録日 | 2021-08-16 | | 公開日 | 2022-08-24 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells.
Sci Adv, 8, 2022
|
|
7PH2
 | | Nanodisc reconstituted MsbA in complex with nanobodies, spin-labeled at position A60C | | 分子名称: | (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{S},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,5-bis(oxidanyl)oxan-2-yl]oxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-4-[(3~{R})-3-nonanoyloxytetradecanoyl]oxy-5-[[(3~{R})-3-octanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{S},5~{S},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanylnonanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-oxan-2-yl]methoxy]-5-oxidanyl-oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase, ... | | 著者 | Januliene, D, Parey, K, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A. | | 登録日 | 2021-08-16 | | 公開日 | 2022-08-24 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells.
Sci Adv, 8, 2022
|
|
7PH4
 | | AMP-PNP bound nanodisc reconstituted MsbA with nanobodies, spin-labeled at position T68C | | 分子名称: | (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, ATP-dependent lipid A-core flippase, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Parey, K, Januliene, D, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A. | | 登録日 | 2021-08-16 | | 公開日 | 2022-08-24 | | 最終更新日 | 2022-10-26 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells.
Sci Adv, 8, 2022
|
|
7D7R
 | | Cryo-EM structure of the core domain of human ABCB6 transporter | | 分子名称: | ATP-binding cassette sub-family B member 6, mitochondrial | | 著者 | Wang, C, Cao, C, Wang, N, Wang, X, Zhang, X.C. | | 登録日 | 2020-10-05 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-electron microscopy structure of human ABCB6 transporter.
Protein Sci., 29, 2020
|
|
7EHL
 | | Cryo-EM structure of human ABCB8 transporter in nucleotide binding state | | 分子名称: | CHOLESTEROL, MAGNESIUM ION, Mitochondrial potassium channel ATP-binding subunit, ... | | 著者 | Li, S.J, Yang, X, Shen, Y.Q. | | 登録日 | 2021-03-29 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY | | 主引用文献 | Cryo-EM structure of human ABCB8 transporter in nucleotide binding state.
Biochem.Biophys.Res.Commun., 557, 2021
|
|
7EKM
 | | Mitochondrial outer membrane protein | | 分子名称: | ATP-binding cassette sub-family B member 6, mitochondrial | | 著者 | Zhang, S.S. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Molecular insights into the human ABCB6 transporter.
Cell Discov, 7, 2021
|
|
7EKL
 | | Mitochondrial outer membrane protein | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family B member 6, MAGNESIUM ION | | 著者 | Zhang, S.S. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-25 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular insights into the human ABCB6 transporter.
Cell Discov, 7, 2021
|
|
7DQV
 | | Crystal structure of a CmABCB1 mutant | | 分子名称: | DECYL-BETA-D-MALTOPYRANOSIDE, MAGNESIUM ION, NITRATE ION, ... | | 著者 | Matsuoka, K, Nakatsu, T, Kato, H. | | 登録日 | 2020-12-24 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The crystal structure of the CmABCB1 G132V mutant, which favors the outward-facing state, reveals the mechanism of the pivotal joint between TM1 and TM3.
Protein Sci., 30, 2021
|
|
