PDB: 225399 件ウェブページステータス検索Chemie searchBIRD

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4GOE	Crystal structure of the SGTA homodimerization domain with a covalent modification of a single C38 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Small glutamine-rich tetratricopeptide repeat-containing protein alpha 著者 Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M. 登録日 2012-08-19 公開日 2012-11-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface. Cell Rep, 2, 2012
3VVI	Crystal structure of the coiled-coil domain of the transient receptor potential channel from Gibberella zeae (TRPGz) 分子名称: ACETATE ION, Non selective cation channel homologous to TRP channel 著者 Ihara, M, Yamashita, A. 登録日 2012-07-25 公開日 2013-04-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Molecular bases of multimodal regulation of a fungal transient receptor potential (TRP) channel J.Biol.Chem., 288, 2013
4GOX	Sulfotransferase Domain from the Synechococcus PCC 7002 Olefin Synthase 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Polyketide synthase 著者 McCarthy, J.G, Smith, J.L. 登録日 2012-08-20 公開日 2012-10-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis of functional group activation by sulfotransferases in complex metabolic pathways. Acs Chem.Biol., 7, 2012
4GPC	Structure of the biliverdin-HmuO, heme oxygenase from Corynebacterium diphtheriae 分子名称: ASCORBIC ACID, BILIVERDINE IX ALPHA, Heme oxygenase, ... 著者 Unno, M, Ikeda-Saito, M. 登録日 2012-08-20 公開日 2013-08-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structures of the Substrate-Free and the Product-Bound forms of HmuO, a Heme Oxygenase from Corynebacterium diphtheriae To be Published
4GNK	Crystal structure of Galphaq in complex with full-length human PLCbeta3 分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Lyon, A.M, Tesmer, J.J.G. 登録日 2012-08-17 公開日 2013-02-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Full-length G alpha (q)-phospholipase C-beta 3 structure reveals interfaces of the C-terminal coiled-coil domain. Nat.Struct.Mol.Biol., 20, 2013
4GPS	Crystal Structure of K. lactis Dxo1 (YDR370C) 分子名称: CITRIC ACID, KLLA0E02245p 著者 Chang, J.H, Chiba, K, Tong, L. 登録日 2012-08-21 公開日 2012-09-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Dxo1 is a new type of eukaryotic enzyme with both decapping and 5'-3' exoribonuclease activity. Nat.Struct.Mol.Biol., 19, 2012
3VWO	Crystal structure of peptidoglycan hydrolase mutant from Sphingomonas sp. A1 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Peptidoglycan hydrolase FlgJ 著者 Maruyama, Y, Mikami, B, Hashimoto, W, Murata, K. 登録日 2012-08-30 公開日 2013-09-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Crystal structure of peptidoglycan hydrolase mutant from Sphingomonas sp. A1 To be Published
3VCB	C425S mutant of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59 分子名称: RNA-directed RNA polymerase 著者 Xu, X, Lou, Z, Ma, Y, Chen, X, Yang, Z, Tong, X, Zhao, Q, Xu, Y, Deng, H, Bartlam, M, Rao, Z. 登録日 2012-01-03 公開日 2012-01-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59. Plos One, 4, 2009
4GOY	The crystal structure of human fascin 1 K41A mutant 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BROMIDE ION, CHLORIDE ION, ... 著者 Yang, S.Y, Huang, F.K, Huang, J, Chen, S, Jakoncic, J, Leo-Macias, A, Diaz-Avalos, R, Chen, L, Zhang, J.J, Huang, X.Y. 登録日 2012-08-20 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular mechanism of fascin function in filopodial formation. J.Biol.Chem., 288, 2013
4GPG	X/N joint refinement of Achromobacter Lyticus Protease I free form at pD8.0 分子名称: Protease 1 著者 Ohnishi, Y, Yamada, T, Kurihara, K, Tanaka, I, Sakiyama, F, Masaki, T, Niimura, N. 登録日 2012-08-21 公開日 2013-09-11 最終更新日 2023-11-08 実験手法 NEUTRON DIFFRACTION (1.895 Å), X-RAY DIFFRACTION 主引用文献 Neutron and X-ray crystallographic analysis of Achromobacter protease I at pD 8.0: protonation states and hydration structure in the free-form. Biochim.Biophys.Acta, 1834, 2013
4GQ3	Human menin with bound inhibitor MI-2 分子名称: 4-[4-(5,5-dimethyl-4,5-dihydro-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine, DI(HYDROXYETHYL)ETHER, Menin, ... 著者 Shi, A, Murai, M.J, He, S, Lund, G.L, Hartley, T, Purohit, T, Reddy, G, Chruszcz, M, Grembecka, J, Cierpicki, T. 登録日 2012-08-22 公開日 2012-09-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia. Blood, 120, 2012
4GSU	Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains 分子名称: (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Probable conserved lipoprotein LPPS 著者 Kim, H.S, Kim, J, Im, H.N, Yoon, J.Y, An, D.R, Yoon, H.J, Kim, J.Y, Min, H.K, Kim, S.-J, Lee, J.Y, Han, B.W, Suh, S.W. 登録日 2012-08-28 公開日 2013-02-27 最終更新日 2022-02-09 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains Acta Crystallogr.,Sect.D, 69, 2013
3VE5	Structure of recombination mediator protein RecR16-196 deletion mutant 分子名称: IMIDAZOLE, Recombination protein recR, ZINC ION 著者 Tang, Q, Yan, X.X, Liang, D.C. 登録日 2012-01-07 公開日 2012-12-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 RecOR complex including RecR N-N dimer and RecO monomer displays a high affinity for ssDNA Nucleic Acids Res., 40, 2012
4GQL	Crystal structure of the catalytic domain of Human MMP12 in complex with selective phosphinic inhibitor RXP470.1 分子名称: CALCIUM ION, Macrophage metalloelastase, N-[(2S)-3-[(S)-(4-bromophenyl)(hydroxy)phosphoryl]-2-{[3-(3'-chlorobiphenyl-4-yl)-1,2-oxazol-5-yl]methyl}propanoyl]-L-alpha-glutamyl-L-alpha-glutamine, ... 著者 Stura, E.A, Vera, L, Beau, F, Devel, L, Cassar-Lajeunesse, E, Dive, V. 登録日 2012-08-23 公開日 2013-02-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies. J.Med.Chem., 56, 2013
3VEH	Structure of a M. tuberculosis salicylate synthase, MbtI, in complex with an inhibitor methylAMT 分子名称: 3-{[(1Z)-1-carboxyprop-1-en-1-yl]oxy}-2-hydroxybenzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Bulloch, E.M, Chi, G, Manos-Turvey, A, Johnston, J.M, Baker, E.N, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) 登録日 2012-01-08 公開日 2012-06-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis. Biochemistry, 51, 2012
4GQW	Crystal structure of CBS-pair protein, CBSX1 (loop deletion) from Arabidopsis thaliana 分子名称: CBS domain-containing protein CBSX1, chloroplastic 著者 Jeong, B.-C, Song, H.K. 登録日 2012-08-24 公開日 2013-01-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Crystal structure of CBSX1 (loop deletion) Biochem.Biophys.Res.Commun., 2012
3VF7	Crystal Structure of HIV-1 Protease Mutant L76V with novel P1'-Ligands GRL-02031 分子名称: (3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-([(4-methoxyphenyl)sulfonyl]{[(2R)-5-oxopyrrolidin-2-yl]methyl}amino)propyl]carbamate, CHLORIDE ION, GLYCEROL, ... 著者 Yu, X.X, Wang, Y.F, Chang, Y.C.E, Weber, I.T. 登録日 2012-01-09 公開日 2012-11-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring. J.Med.Chem., 55, 2012
4GR3	Crystal structure of the catalytic domain of Human MMP12 in complex with selective phosphinic inhibitor RXP470A 分子名称: CALCIUM ION, Macrophage metalloelastase, N-{(2S)-3-[(S)-(4-bromophenyl)(hydroxy)phosphoryl]-2-[(3-phenyl-1,2-oxazol-5-yl)methyl]propanoyl}-L-alpha-glutamyl-L-al pha-glutamine, ... 著者 Stura, E.A, Vera, L, Beau, F, Devel, L, Cassar-Lajeunesse, E, Dive, V. 登録日 2012-08-24 公開日 2013-02-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.494 Å) 主引用文献 Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies. J.Med.Chem., 56, 2013
3VIH	Crystal structure of beta-glucosidase from termite Neotermes koshunensis in complex with glycerol 分子名称: Beta-glucosidase, CHLORIDE ION, GLYCEROL, ... 著者 Jeng, W.Y, Liu, C.I, Wang, A.H.J. 登録日 2011-10-03 公開日 2012-07-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.03 Å) 主引用文献 High-resolution structures of Neotermes koshunensis beta-glucosidase mutants provide insights into the catalytic mechanism and the synthesis of glucoconjugates Acta Crystallogr.,Sect.D, 68, 2012
3VIU	Crystal structure of PurL from thermus thermophilus 分子名称: ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... 著者 Suzuki, S, Yanai, H, Kanagawa, M, Tamura, S, Watanabe, Y, Fuse, K, Baba, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2011-10-12 公開日 2012-01-18 最終更新日 2012-04-25 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of N-formylglycinamide ribonucleotide amidotransferase II (PurL) from Thermus thermophilus HB8 Acta Crystallogr.,Sect.F, 68, 2012
4GUX	Crystal structure of trypsin:MCoTi-II complex 分子名称: ACETATE ION, CALCIUM ION, Cationic trypsin, ... 著者 King, G.J, Daly, N.L, Thorstholm, L, Greenwood, K.P, Rosengren, K.J, Heras, B, Craik, D.J, Martin, J.L. 登録日 2012-08-30 公開日 2013-09-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor J.Biol.Chem., 288, 2013
8AHO	Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with cyanamide analogue 31 分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, NITRATE ION, ... 著者 de Munnik, M, Lang, P.A, Brem, J, Schofield, C.J. 登録日 2022-07-22 公開日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 High-throughput screen with the l,d-transpeptidase Ldt Mt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors. Chem Sci, 14, 2023
3VLJ	Crystal Structure Analysis of the Cyanide Arg409Leu Variant Complexes with o-Dianisidine in KatG from HALOARCULA MARISMORTUI 分子名称: 3,3'-dimethoxybiphenyl-4,4'-diamine, CYANIDE ION, Catalase-peroxidase 2, ... 著者 Sato, T, Higuchi, W, Yoshimatsu, K, Fujiwara, T. 登録日 2011-12-01 公開日 2012-12-05 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structures and Peroxidatic Function of Cyanide Arg409Leu Variant and its Complexes with o-Dianisidine in KatG from HALOARCULA MARISMORTUI To be Published
4GVQ	X-ray structure of the Archaeoglobus fulgidus methenyl-tetrahydromethanopterin cyclohydrolase in complex with tetrahydromethanpterin 分子名称: 1-[4-({(1R)-1-[(6S,7S)-2-amino-7-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]ethyl}amino)phenyl]-1-deoxy-5-O-{5-O-[(R)-{[(1R)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-xylitol, Methenyltetrahydromethanopterin cyclohydrolase 著者 Upadhyay, V, Demmer, U, Warkentin, E, Moll, J, Shima, S, Ermler, U. 登録日 2012-08-31 公開日 2012-10-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure and catalytic mechanism of N(5),N(10)-methenyl-tetrahydromethanopterin cyclohydrolase. Biochemistry, 51, 2012
3VNG	Crystal Structure of Keap1 in Complex with Synthetic Small Molecular based on a co-crystallization 分子名称: 2-(3-((3-(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)ureido)methyl)phenoxy)acetic acid, Kelch-like ECH-associated protein 1 著者 Kunishima, N, Tanaka, T, Satoh, M, Saburi, H. 登録日 2012-01-12 公開日 2013-01-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Keap1 in Complex with Synthetic Small Molecular based on a co-crystallization To be Published

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