PDB: 225399 件ウェブページステータス検索Chemie searchBIRD

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3VZ2	Structural insights into substrate and cofactor selection by sp2771 分子名称: Succinate-semialdehyde dehydrogenase 著者 Yuan, Y.A, Yuan, Z, Yin, B, Wei, D. 登録日 2012-10-09 公開日 2013-10-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase J.Struct.Biol., 182, 2013
4GF7	Crystal structure of 2-Methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO), unliganded form 分子名称: 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... 著者 Kobayashi, J, Yoshida, H, Mikami, B, Hayashi, H, Kamitori, S, Sawa, Y, Yagi, T. 登録日 2012-08-03 公開日 2013-08-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.581 Å) 主引用文献 Crystal structure of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase To be Published
4GHR	TGT D102N mutant in complex with lin-benzohypoxanthine inhibitor 分子名称: 2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, GLYCEROL, Queuine tRNA-ribosyltransferase, ... 著者 Immekus, F, Klebe, G. 登録日 2012-08-08 公開日 2013-09-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Protonation state analysis of the TGT active site To be Published
3W05	Crystal structure of Oryza sativa DWARF14 (D14) in complex with PMSF 分子名称: 1,2-ETHANEDIOL, Dwarf 88 esterase, phenylmethanesulfonic acid 著者 Kagiyama, M, Hirano, Y, Mori, T, Kim, S.Y, Kyozuka, J, Seto, Y, Yamaguchi, S, Hakoshima, T. 登録日 2012-10-19 公開日 2013-01-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structures of D14 and D14L in the strigolactone and karrikin signaling pathways Genes Cells, 18, 2013
4GGL	Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity 分子名称: 7-({4-[(3R)-3-aminopyrrolidin-1-yl]-5-chloro-6-ethyl-7H-pyrrolo[2,3-d]pyrimidin-2-yl}sulfanyl)pyrido[2,3-b]pyrazin-2(1H)-one, DNA gyrase subunit B, GLYCEROL 著者 Bensen, D.C, Creighton, C.J, Tari, L.W. 登録日 2012-08-06 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. Bioorg.Med.Chem.Lett., 23, 2013
3V7S	Crystal structure of Staphylococcus aureus biotin protein ligase in complex with inhibitor 0364 分子名称: 5-methyl-3-[4-(4-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl}-1H-1,2,3-triazol-1-yl)butyl]-1,3-benzoxazol-2(3H)-one, Biotin ligase 著者 Yap, M.Y, Pendini, N.R. 登録日 2011-12-21 公開日 2012-04-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Selective inhibition of biotin protein ligase from Staphylococcus aureus. J.Biol.Chem., 287, 2012
4GK3	Human EphA3 Kinase domain in complex with ligand 87 分子名称: 8-butyl-1-methyl-7-(2-methylphenyl)-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione, EPH receptor A3 著者 Dong, J, Caflisch, A. 登録日 2012-08-10 公開日 2013-01-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Optimization of Inhibitors of the Tyrosine Kinase EphB4. 2. Cellular Potency Improvement and Binding Mode Validation by X-ray Crystallography. J.Med.Chem., 56, 2013
3VZ1	Structural insights into substrate and cofactor selelction by sp2771 分子名称: Succinate-semialdehyde dehydrogenase 著者 Yuan, Y.A, Yuan, Z, Yin, B, Wei, D. 登録日 2012-10-09 公開日 2013-07-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for cofactor and substrate selection by cyanobacterium succinic semialdehyde dehydrogenase J.Struct.Biol., 182, 2013
3VZR	Crystal structure of T173S mutant of PhaB from Ralstonia eutropha 分子名称: Acetoacetyl-CoA reductase 著者 Ikeda, K, Tanaka, Y, Tanaka, I, Yao, M. 登録日 2012-10-15 公開日 2013-08-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 Directed evolution and structural analysis of NADPH-dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) reductase from Ralstonia eutropha reveals two mutations responsible for enhanced kinetics Appl.Environ.Microbiol., 79, 2013
3W02	Crystal structure of PcrB complexed with SO4 from Staphylococcus aureus subsp. aureus Mu3 分子名称: Heptaprenylglyceryl phosphate synthase, SULFATE ION 著者 Ren, F, Feng, X, Ko, T.P, Huang, C.H, Hu, Y, Chan, H.C, Liu, Y.L, Wang, K, Chen, C.C, Pang, X, He, M, Li, Y, Oldfield, E, Guo, R.T. 登録日 2012-10-17 公開日 2012-12-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus Chembiochem, 14, 2013
4GKF	Crystal structure and characterization of Cmr5 protein from Pyrococcus furiosus 分子名称: CRISPR system Cmr subunit Cmr5 著者 Park, J, Sun, J, Park, S, Hwang, H, Park, M, Shin, M.S. 登録日 2012-08-11 公開日 2013-01-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of Cmr5 from Pyrococcus furiosus and its functional implications Febs Lett., 587, 2013
8ANO	Fucosylated mixed-chirality linear peptide FHP8 bound to the fucose binding lectin LecB PA-IIL from Pseudomonas aeruginosa at 1.3 Angstrom resolution. 分子名称: 3,7-anhydro-2,8-dideoxy-L-glycero-D-gluco-octonic acid, CALCIUM ION, Fucose-binding lectin PA-IIL, ... 著者 Personne, H, Stocker, A, Reymond, J.-L. 登録日 2022-08-05 公開日 2023-05-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 To Fold or Not to Fold: Diastereomeric Optimization of an alpha-Helical Antimicrobial Peptide. J.Med.Chem., 66, 2023
3VBK	Crystal Structure of the S84A mutant of AntD, an N-acyltransferase from Bacillus cereus in complex with dTDP-4-amino-4,6-dideoxyglucose and Coenzyme A 分子名称: BICARBONATE ION, CHLORIDE ION, COENZYME A, ... 著者 Kubiak, R.L, Holden, H.M. 登録日 2012-01-02 公開日 2012-01-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Studies of AntD: An N-Acyltransferase Involved in the Biosynthesis of d-Anthrose. Biochemistry, 51, 2012
3W0F	Crystal structure of mouse Endonuclease VIII-LIKE 3 (mNEIL3) 分子名称: Endonuclease 8-like 3, IODIDE ION, ZINC ION 著者 Liu, M, Imamura, K, Averill, A.M, Wallace, S.S, Doublie, S. 登録日 2012-10-30 公開日 2013-01-16 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA Structure, 21, 2013
3VBT	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design 分子名称: 4-chloro-2-(1H-pyrazol-3-yl)phenol, Serine/threonine-protein kinase pim-1 著者 Liu, J. 登録日 2012-01-02 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
3VC5	Crystal structure of enolase Tbis_1083(TARGET EFI-502310) FROM Thermobispora bispora DSM 43833 complexed with phosphate 分子名称: Mandelate racemase/muconate lactonizing protein, PHOSPHATE ION 著者 Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2012-01-03 公開日 2012-02-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of enolase Tbis_1083 FROM Thermobispora bispora DSM 43833 To be Published
4GK2	Human EphA3 Kinase domain in complex with ligand 66 分子名称: 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione, EPH receptor A3 著者 Dong, J, Caflisch, A. 登録日 2012-08-10 公開日 2013-01-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.195 Å) 主引用文献 Optimization of Inhibitors of the Tyrosine Kinase EphB4. 2. Cellular Potency Improvement and Binding Mode Validation by X-ray Crystallography. J.Med.Chem., 56, 2013
4GM6	Crystal structure of PfkB family carbohydrate kinase(TARGET EFI-502146 FROM Listeria grayi DSM 20601 分子名称: CHLORIDE ION, GLYCEROL, PfkB family carbohydrate kinase 著者 Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2012-08-15 公開日 2012-09-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of PfkB family carbohydrate kinase FROM Listeria grayi To be Published
3VDP	Structure and biochemical studies of the recombination mediator protein RecR in RecFOR pathway 分子名称: IMIDAZOLE, Recombination protein recR, ZINC ION 著者 Tang, Q, Yan, X.X, Liang, D.C. 登録日 2012-01-05 公開日 2012-12-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.451 Å) 主引用文献 RecOR complex including RecR N-N dimer and RecO monomer displays a high affinity for ssDNA Nucleic Acids Res., 40, 2012
4GHC	Structure of Y257F variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum at 1.55 Ang resolution 分子名称: CALCIUM ION, CHLORIDE ION, FE (II) ION, ... 著者 Kovaleva, E.G, Lipscomb, J.D. 登録日 2012-08-07 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural basis for the role of tyrosine 257 of homoprotocatechuate 2,3-dioxygenase in substrate and oxygen activation. Biochemistry, 51, 2012
4GMH	Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase 分子名称: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ACETATE ION 著者 Brown, R.L, Anderson, B.F, Norris, G.E, Tyler, P.C, Evans, G.B, Sutherland-Smith, A.J. 登録日 2012-08-15 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase To be Published
4GIH	Tyk2 (JH1) in complex with 2,6-DICHLORO-N-{2-[(CYCLOPROPYLCARBONYL)AMINO]PYRIDIN-4-YL}BENZAMIDE 分子名称: 2,6-dichloro-N-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamide, Non-receptor tyrosine-protein kinase TYK2 著者 Ultsch, M.H. 登録日 2012-08-08 公開日 2013-06-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Lead identification of novel and selective TYK2 inhibitors. Eur.J.Med.Chem., 67, 2013
4GML	Crystal structure of human NOT1 MIF4G domain 分子名称: CCR4-NOT transcription complex subunit 1 著者 Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E. 登録日 2012-08-16 公開日 2012-10-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex Nucleic Acids Res., 40, 2012
4GN7	mouse SMP30/GNL 分子名称: CALCIUM ION, Regucalcin, SULFATE ION 著者 Aizawa, S, Senda, M, Harada, A, Maruyama, N, Ishida, T, Aigaki, T, Ishigami, A, Senda, T. 登録日 2012-08-17 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis of the gamma-lactone-ring formation in ascorbic acid biosynthesis by the senescence marker protein-30/gluconolactonase Plos One, 8, 2013
3VB9	Crystal structure of VPA0735 from Vibrio parahaemolyticus in monoclinic form, NorthEast Structural Genomics target VpR109 分子名称: MAGNESIUM ION, Uncharacterized protein VPA0735 著者 Seetharaman, J, Neely, H, Cunningham, K, Ciccosanti, C, Bjelic, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) 登録日 2011-12-31 公開日 2012-05-23 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of VPA0735 from Vibrio parahaemolyticus in monoclinic form, NorthEast Structural Genomics target VpR109 To be Published

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