PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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4WLM	Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese 分子名称: MANGANESE (II) ION, SULFATE ION, Xyloside xylosyltransferase 1 著者 Yu, H, Li, H. 登録日 2014-10-07 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism. Nat.Chem.Biol., 11, 2015
4WLG	crystal structure of mouse Xyloside xylosyltransferase 1, apo form 分子名称: SULFATE ION, Xyloside xylosyltransferase 1 著者 Yu, H, Li, H. 登録日 2014-10-07 公開日 2015-11-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism. Nat.Chem.Biol., 11, 2015
4WMB	crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, acceptor ligand and UDP 分子名称: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ... 著者 Yu, H, Li, H. 登録日 2014-10-08 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism. Nat.Chem.Biol., 11, 2015
4WMK	Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex II) 分子名称: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ... 著者 Yu, H, Li, H. 登録日 2014-10-09 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism. Nat.Chem.Biol., 11, 2015
6EWQ	Putative sugar aminotransferase Spr1654 from Streptococcus pneumoniae, PLP-form 分子名称: PYRIDOXAL-5'-PHOSPHATE, Putative capsular polysaccharide biosynthesis protein 著者 Achour, A, Sun, R, Sandalova, T, Han, X. 登録日 2017-11-06 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis inStreptococcus pneumoniae. Open Biol, 8, 2018
6H17	Myxococcus xanthus MglA bound to GTPgammaS 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Mutual gliding-motility protein MglA, ... 著者 Galicia, C, Cherfils, J. 登録日 2018-07-11 公開日 2019-11-27 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.275 Å) 主引用文献 MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus. Nat Commun, 10, 2019
4JF0	N79R mutant of N-acetylornithine aminotransferase 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Acetylornithine/succinyldiaminopimelate aminotransferase, ... 著者 Bisht, S, Bharath, S.R, Murthy, M.R.N. 登録日 2013-02-27 公開日 2014-03-26 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases To be Published
6EZL	Crystal structure of aspartate aminotransferase from Trypanosoma cruzi at 2.07 Angstrom resolution 分子名称: Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Jagoe, W.N, Khan, A.R. 登録日 2017-11-15 公開日 2018-12-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structure of aspartate aminotransferase from Trypanosoma Cruzi at 2.07 Angstrom resolution To Be Published
6EWJ	Putative sugar aminotransferase Spr1654 from Streptococcus pneumoniae, apo-form 分子名称: Putative capsular polysaccharide biosynthesis protein 著者 Achour, A, Sun, R, Sandalova, T, Han, X. 登録日 2017-11-04 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis inStreptococcus pneumoniae. Open Biol, 8, 2018
6EWR	Putative sugar aminotransferase Spr1654 from Streptococcus pneumoniae, PMP-form 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Putative capsular polysaccharide biosynthesis protein 著者 Achour, A, Sun, R, Sandalova, T, Han, X. 登録日 2017-11-06 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis inStreptococcus pneumoniae. Open Biol, 8, 2018
5L1B	AMPA subtype ionotropic glutamate receptor GluA2 in Apo state 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2,Glutamate receptor 2 著者 Yelshanskaya, M.V, Singh, A.K, Sampson, J.M, Sobolevsky, A.I. 登録日 2016-07-28 公開日 2016-10-19 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural Bases of Noncompetitive Inhibition of AMPA-Subtype Ionotropic Glutamate Receptors by Antiepileptic Drugs. Neuron, 91, 2016
4JF1	R144Q mutant of N-acetylornithine aminotransferase 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Acetylornithine/succinyldiaminopimelate aminotransferase, ... 著者 Bisht, S, Bharath, S.R, Murthy, M.R.N. 登録日 2013-02-27 公開日 2014-03-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases To be Published
5MYX	Structure of Pyroglutamate-Abeta-specific Fab c#24 in complex with human Abeta-pE3-18 分子名称: Fab c#24 heavy chain, Fab c#24 light chain, Pyroglutamate-Abeta pE3-18 著者 Parthier, C, Piechotta, A, Stubbs, M.T. 登録日 2017-01-30 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.492 Å) 主引用文献 Structural and functional analyses of pyroglutamate-amyloid-beta-specific antibodies as a basis for Alzheimer immunotherapy. J. Biol. Chem., 292, 2017
4WLZ	Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese and UDP 分子名称: MANGANESE (II) ION, SULFATE ION, URIDINE-5'-DIPHOSPHATE, ... 著者 Yu, H, Li, H. 登録日 2014-10-08 公開日 2015-11-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism. Nat.Chem.Biol., 11, 2015
4JEY	E198A mutant of N-acetylornithine aminotransferase from Salmonella typhimurium 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Acetylornithine/succinyldiaminopimelate aminotransferase, ... 著者 Bisht, S, Bharath, S.R, Murthy, M.R.N. 登録日 2013-02-27 公開日 2014-03-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Conformational transitions, ligand specificity and catalysis in N-acetylornithine aminotransferase: Implications on drug designing and rational enzyme engineering in omega aminotransferases To be Published
6G1F	Crystal structure of D-phenylglycine aninotransferase (D-PhgAT) from Pseudomonas stutzeri with PLP internal aldimine 分子名称: D-phenylglycine aminotransferase 著者 Serpico, A, Marles-Wright, J, Campopiano, D.J. 登録日 2018-03-21 公開日 2019-04-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.248 Å) 主引用文献 D-Phenylglycine aminotransferase (D-PhgAT) – substrate scope and structural insights of a stereo-inverting biocatalyst used in the preparation of aromatic amino acids Catalysis Science And Technology, 2020
6V8D	Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators 分子名称: (3Z)-3-iminocyclohex-1-ene-1-carboxylic acid, Ornithine aminotransferase, mitochondrial, ... 著者 Zhu, W, Doubleday, P.T, Catlin, D.S, Weerawarna, P, Butrin, A, Shen, S, Kelleher, N.L, Liu, D, Silverman, R.B. 登録日 2019-12-10 公開日 2020-12-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators To Be Published
4WMI	Crystal structure of mouse Xyloside xylosyltransferase 1 complexed with manganese, product ligand and UDP (Product complex I) 分子名称: Coagulation factor IX, MANGANESE (II) ION, SULFATE ION, ... 著者 Yu, H, Li, H. 登録日 2014-10-09 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Notch-modifying xylosyltransferase structures support an SNi-like retaining mechanism. Nat.Chem.Biol., 11, 2015
4CBR	X-ray structure of the more stable human AGXT triple mutant (AGXT_HEM) 分子名称: GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SERINE--PYRUVATE AMINOTRANSFERASE 著者 Yunta, C, Albert, A. 登録日 2013-10-16 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Consensus-Based Approach for Gene/Enzyme Replacement Therapies and Crystallization Strategies: The Case of Human Alanine:Glyoxylate Aminotransferase. Biochem.J., 462, 2014
5EFS	The crystal structure of human kynurenine aminotransferase II 分子名称: Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial 著者 Nematollahi, A, Sun, G, Kwan, A, Harrop, S.J, Hanrahan, J.R, Nadvi, N.A, Church, W.B. 登録日 2015-10-26 公開日 2015-11-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.82503 Å) 主引用文献 The crystal structure of human kynurenine aminotransferase II To Be Published
6V8C	Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators 分子名称: 3-aminocyclohexa-1,3-diene-1-carboxylic acid, Ornithine aminotransferase, mitochondrial, ... 著者 Zhu, W, Doubleday, P.T, Catlin, D.S, Weerawarna, P, Butrin, A, Shen, S, Kelleher, N.L, Liu, D, Silverman, R.B. 登録日 2019-12-10 公開日 2020-12-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design, Synthesis, and Mechanism of Fluorine-substituted Cyclohexene Analogues of GAMA-Aminobutyric Acid (GABA) as Selective Ornithine Aminotransferase Inactivators To Be Published
3NWW	P38 Alpha kinase complexed with a 2-aminothiazol-5-yl-pyrimidine based inhibitor 分子名称: 1-[2-(2-{[2-(dimethylamino)ethyl]amino}-6-{2-[(1-methylethyl)amino]-1,3-thiazol-5-yl}pyrimidin-4-yl)benzyl]-3-ethylurea, Mitogen-activated protein kinase 14 著者 Sack, J.S. 登録日 2010-07-12 公開日 2010-09-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Utilization of a nitrogen-sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38alpha MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
5FL1	Structure of a hydrolase with an inhibitor 分子名称: (3~{a}~{R},5~{R},6~{S},7~{R},7~{a}~{R})-5-(hydroxymethyl)-2-(prop-2-enylamino)-5,6,7,7~{a}-tetrahydro-3~{a}~{H}-pyrano[3,2-d][1,3]thiazole-6,7-diol, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Cekic, N, Heinonen, J.E, Stubbs, K.A, Roth, C, McEachern, E.J, Davies, G.J, Vocadlo, D.J. 登録日 2015-10-20 公開日 2016-08-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by humanO-GlcNAcase. Chem Sci, 7, 2016
5FL0	Structure of a hydrolase with an inhibitor 分子名称: (3~{a}~{R},5~{R},6~{S},7~{R},7~{a}~{R})-2-(butylamino)-5-(hydroxymethyl)-5,6,7,7~{a}-tetrahydro-3~{a}~{H}-pyrano[3,2-d] [1,3]thiazole-6,7-diol, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Cekic, N, Heinonen, J.E, Stubbs, K.A, Roth, C, McEachern, E.J, Davies, G.J, Vocadlo, D.J. 登録日 2015-10-20 公開日 2016-08-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by humanO-GlcNAcase. Chem Sci, 7, 2016
8OHM	CRYSTAL STRUCTURE OF RNA HELICASE FROM GENOTYPE 1B HEPATITIS C VIRUS: MECHANISM OF UNWINDING DUPLEX RNA 分子名称: RNA HELICASE 著者 Cho, H.S, Ha, N.C, Kang, L.W, Oh, B.H. 登録日 1998-03-13 公開日 1999-04-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of RNA helicase from genotype 1b hepatitis C virus. A feasible mechanism of unwinding duplex RNA. J.Biol.Chem., 273, 1998

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