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2B1G
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Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase
分子名称: 7-(3,4-DIHYDROXY-5R-HYDROXYMETHYLTETRAHYDROFURAN-2-YL)-2,2-DIOXO-1,2R,3R,7-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-4S-ONE, Bifunctional purine biosynthesis protein PURH, PHOSPHATE ION, ...
著者Xu, L, Chong, Y, Hwang, I, D'Onofrio, A, Amore, K, Beardsley, G.P, Li, C, Olson, A.J, Boger, D.L, Wilson, I.A.
登録日2005-09-15
公開日2006-11-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase.
J.Biol.Chem., 282, 2007
2P62
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Crystal structure of hypothetical protein PH0156 from Pyrococcus horikoshii OT3
分子名称: Hypothetical protein PH0156
著者Fu, Z.-Q, Chen, L, Zhu, J, Swindell, J.T, Ebihara, A, Shinkai, A, Kuramitsu, S, Yokoyama, S, Chrzas, J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG), RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-03-16
公開日2007-04-17
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of hypothetical protein PH0156 from Pyrococcus horikoshii OT3
To be Published
2P9U
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Crystal structure of bovine Arp2/3 complex co-crystallized with AMP-PNP and calcium
分子名称: Actin-like protein 2, Actin-like protein 3, Actin-related protein 2/3 complex subunit 1B, ...
著者Nolen, B.J, Pollard, T.D.
登録日2007-03-26
公開日2007-05-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
Mol.Cell, 26, 2007
2PBO
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E27Q mutant of EXO-B-(1,3)-Glucanase from Candida Albicans at 1.85 A
分子名称: Hypothetical protein XOG1
著者Cutfield, S.M, Cutfield, J.F, Patrick, W.M.
登録日2007-03-28
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Functional Analysis of Protein:Carbohydrate Interactions at Three Distinct Sites in Candida albicans Exo-beta-1,3-glucanase
To be Published
2P3C
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Crystal Structure of the subtype F wild type HIV protease complexed with TL-3 inhibitor
分子名称: ACETIC ACID, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate, protease
著者Sanches, M, Krauchenco, S, Martins, N.H, Gustchina, A, Wlodawer, A, Polikarpov, I.
登録日2007-03-08
公開日2007-04-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Characterization of B and non-B Subtypes of HIV-Protease: Insights into the Natural Susceptibility to Drug Resistance Development.
J.Mol.Biol., 369, 2007
2PCU
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Human carboxypeptidase A4 in complex with a cleaved hexapeptide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ASPARTIC ACID, Carboxypeptidase A4, ...
著者Bayes, A, Fernandez, D, Sola, M, Marrero, A, Garcia-Pique, S, Aviles, F.X, Vendrell, J, Gomis-Ruth, F.X.
登録日2007-03-30
公開日2007-04-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Caught after the Act: a human A-type metallocarboxypeptidase in a product complex with a cleaved hexapeptide.
Biochemistry, 46, 2007
2P5Z
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The E. coli c3393 protein is a component of the type VI secretion system and exhibits structural similarity to T4 bacteriophage tail proteins gp27 and gp5
分子名称: Type VI secretion system component
著者Ramagopal, U.A, Bonanno, J.B, Sridhar, V, Lau, C, Toro, R, Gheyi, T, Maletic, M, Freeman, J.C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-03-16
公開日2007-04-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin.
Proc.Natl.Acad.Sci.Usa, 106, 2009
2PEM
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BU of 2pem by Molmil
Crystal structure of RbcX in complex with substrate
分子名称: ORF134, RbcL
著者Saschenbrecker, S, Bracher, A, Vasudeva Rao, K, Vasudeva Rao, B, Hartl, F.U, Hayer-Hartl, M.
登録日2007-04-03
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure and Function of RbcX, an Assembly Chaperone for Hexadecameric Rubisco.
Cell(Cambridge,Mass.), 129, 2007
2P9K
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BU of 2p9k by Molmil
Crystal structure of bovine Arp2/3 complex co-crystallized with ATP and crosslinked with glutaraldehyde
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ...
著者Nolen, B.J, Pollard, T.D.
登録日2007-03-26
公開日2007-05-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex.
Mol.Cell, 26, 2007
2PBK
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Crystal structure of KSHV protease in complex with hexapeptide phosphonate inhibitor
分子名称: ACETATE ION, KSHV protease, hexapeptide phosphonate inhibitor
著者Lazic, A, Goetz, D.H.
登録日2007-03-28
公開日2007-12-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Substrate modulation of enzyme activity in the herpesvirus protease family.
J.Mol.Biol., 373, 2007
2PFP
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DNA Polymerase lambda in complex with DNA and dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ...
著者Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A.
登録日2007-04-05
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Role of the catalytic metal during polymerization by DNA polymerase lambda.
DNA Repair, 6, 2007
2QOS
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Crystal structure of complement protein C8 in complex with a peptide containing the C8 binding site on C8
分子名称: Complement component 8, gamma polypeptide, Complement component C8 alpha chain
著者Lovelace, L.L, Chiswell, B, Slade, D.J, Sodetz, J.M, Lebioda, L.
登録日2007-07-20
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: Implications for C8gamma ligand binding.
Mol.Immunol., 45, 2008
2QX0
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Crystal Structure of Yersinia pestis HPPK (Ternary Complex)
分子名称: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ...
著者Blaszczyk, J, Cherry, S, Tropea, J.E, Waugh, D.S, Ji, X.
登録日2007-08-10
公開日2007-10-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and activity of Yersinia pestis 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase as a novel target for the development of antiplague therapeutics.
Acta Crystallogr.,Sect.D, 63, 2007
2R2G
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BU of 2r2g by Molmil
Structure of Eugenol Synthase from Ocimum basilicum complexed with EMDF
分子名称: Eugenol synthase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ethyl (1S,2S)-2-(4-hydroxy-3-methoxyphenyl)cyclopropanecarboxylate
著者Louie, G.V, Noel, J.P, Bowman, M.E.
登録日2007-08-24
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and reaction mechanism of basil eugenol synthase
Plos One, 2, 2007
2R2X
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Ricin A-chain (recombinant) complex with Urea
分子名称: Ricin A chain, SULFATE ION, UREA
著者Carra, J.H, McHugh, C.A, Mulligan, S, Machiesky, L.M, Soares, A.S, Millard, C.B.
登録日2007-08-28
公開日2007-11-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site.
Bmc Struct.Biol., 7, 2007
2R40
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Crystal structure of 20E bound EcR/USP
分子名称: (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one, CITRATE ANION, Ecdysone Receptor, ...
著者Moras, D, Billas, I.M.L, Browning, C.
登録日2007-08-30
公開日2007-10-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor
J.Biol.Chem., 282, 2007
1X9D
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Crystal Structure Of Human Class I alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue
分子名称: 1,4-BUTANEDIOL, CALCIUM ION, Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ...
著者Karaveg, K, Tempel, W, Liu, Z.J, Siriwardena, A, Moremen, K.W, Wang, B.C.
登録日2004-08-20
公開日2005-02-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Mechanism of class 1 (glycosylhydrolase family 47) {alpha}-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control.
J.Biol.Chem., 280, 2005
2QDJ
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Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture
分子名称: Retinoblastoma-associated protein
著者Hassler, M, Mittnacht, S, Pearl, L.H.
登録日2007-06-21
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture.
Mol.Cell, 28, 2007
2QEH
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Crystal Structure of Anopheles gambiae D7r4-serotonin complex
分子名称: D7R4 Protein, SEROTONIN
著者Andersen, J.F, Mans, B.J, Calvo, E, Ribeiro, J.M.
登録日2007-06-25
公開日2007-10-09
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献The Crystal Structure of D7r4, a Salivary Biogenic Amine-binding Protein from the Malaria Mosquito Anopheles gambiae
J.Biol.Chem., 282, 2007
2QF4
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High resolution structure of the major periplasmic domain from the cell shape-determining filament MreC (orthorhombic form)
分子名称: 1,2-ETHANEDIOL, Cell shape determining protein MreC, SULFATE ION
著者Lovering, A.L, Strynadka, N.C.J.
登録日2007-06-26
公開日2007-08-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献High-resolution Structure of the Major Periplasmic Domain from the Cell Shape-determining Filament MreC.
J.Mol.Biol., 372, 2007
2QFC
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Crystal Structure of Bacillus thuringiensis PlcR complexed with PapR
分子名称: C-terminus pentapeptide from PapR protein, DI(HYDROXYETHYL)ETHER, PlcR protein
著者Declerck, N, Chaix, D, Rugani, N, Hoh, F, Arold, S.T.
登録日2007-06-27
公開日2007-11-06
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of PlcR: Insights into virulence regulation and evolution of quorum sensing in Gram-positive bacteria
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QGC
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Human transthyretin (TTR) complexed with 2-(3,5-Dimethyl-4-hydroxyphenyl)benzoxazole
分子名称: 4-(1,3-BENZOXAZOL-2-YL)-2,6-DIMETHYLPHENOL, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QGI
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The UDP complex structure of the sixth gene product of the F1-ATPase operon of Rhodobacter blasticus
分子名称: ATP synthase subunits region ORF 6, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE
著者Enroth, C, Strid, A.
登録日2007-06-29
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of a protein, structurally related to glycosyltransferases, encoded in the Rhodobacter blasticus atp operon.
Biochim.Biophys.Acta, 1784, 2008
2QGY
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Crystal structure of an enolase from the environmental genome shotgun sequencing of the Sargasso Sea
分子名称: Enolase from the environmental genome shotgun sequencing of the Sargasso Sea, MAGNESIUM ION
著者Bonanno, J.B, Gilmore, M, Bain, K.T, Lau, C, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-06-29
公開日2007-07-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of an enolase from the environmental genome shotgun sequencing of the Sargasso Sea.
To be Published
2QFV
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Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with NADP(+)
分子名称: Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Peng, Y.J, Ding, J.P.
登録日2007-06-28
公開日2008-07-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction
Protein Sci., 17, 2008

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