PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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2VGP	Crystal structure of Aurora B kinase in complex with a aminothiazole inhibitor 分子名称: 4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-methylbenzamide, INNER CENTROMERE PROTEIN A, SERINE/THREONINE-PROTEIN KINASE 12-A 著者 Andersen, C.B, Wan, Y, Chang, J.W, Lee, C, Liu, Y, Sessa, F, Villa, F, Nallan, L, Musacchio, A, Gray, N.S. 登録日 2007-11-15 公開日 2008-02-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of Selective Aminothiazole Aurora Kinase Inhibitors Acs Chem.Biol., 3, 2008
5WPI	The virulence-associated protein HsvA from the fire blight pathogen Erwinia amylovora is a polyamine amidinotransferase 分子名称: 1,2-ETHANEDIOL, HsvA 著者 Shanker, S, Lawton, J. 登録日 2017-08-04 公開日 2017-11-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The virulence-associated protein HsvA from the fire blight pathogen Erwinia amylovora is a polyamine amidinotransferase. J. Biol. Chem., 292, 2017
6X8R	Pharmacological characterisation and NMR structure of the novel mu-conotoxin SxIIIC, a potent irreversible NaV channel inhibitor 分子名称: SxIIIC peptide 著者 Schroeder, C.I, McMahon, K.L. 登録日 2020-06-01 公開日 2020-10-21 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Discovery, Pharmacological Characterisation and NMR Structure of the Novel μ-Conotoxin SxIIIC, a Potent and Irreversible Na V Channel Inhibitor. Biomedicines, 8, 2020
6P6R	HCV NS3/4A protease domain of genotype 1a3a chimera in complex with glecaprevir 分子名称: (3aR,7S,10S,12R,21E,24aR)-7-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}cyclop ropyl]-20,20-difluoro-5,8-dioxo-2,3,3a,5,6,7,8,11,12,20,23,24a-dodecahydro-1H,10H-9,12-methanocyclopenta[18,19][1,10,17, 3,6]trioxadiazacyclononadecino[11,12-b]quinoxaline-10-carboxamide, 1,2-ETHANEDIOL, ... 著者 Timm, J, Schiffer, C.A. 登録日 2019-06-04 公開日 2020-06-10 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Molecular mechanism of pan-genotypic HCV NS3/4A protease inhibition by glecaprevir and characterization of genotype-specific structural differences To Be Published
5JBD	4,6-alpha-glucanotransferase GTFB from Lactobacillus reuteri 121 分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ... 著者 Pijning, T, Dijkstra, B.W, Bai, Y, Gangoiti-Munecas, J, Dijkhuizen, L. 登録日 2016-04-13 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of 4,6-alpha-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from alpha-Amylases in Oral Bacteria. Structure, 25, 2017
5JBF	4,6-alpha-glucanotransferase GTFB (D1015N mutant) from Lactobacillus reuteri 121 complexed with maltopentaose 分子名称: CALCIUM ION, Inactive glucansucrase, SULFATE ION, ... 著者 Pijning, T, Dijkstra, B.W, Bai, Y, Gangoiti-Munecas, J, Dijkhuizen, L. 登録日 2016-04-13 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Crystal Structure of 4,6-alpha-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from alpha-Amylases in Oral Bacteria. Structure, 25, 2017
1TU5	Crystal structure of bovine plasma copper-containing amine oxidase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Lunelli, M, Di Paolo, M.L, Biadene, M, Calderone, V, Scarpa, M, Battistutta, R, Rigo, A, Zanotti, G. 登録日 2004-06-24 公開日 2005-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Crystal structure of amine oxidase from bovine serum. J.Mol.Biol., 346, 2005
5JBE	4,6-alpha-glucanotransferase GTFB from Lactobacillus reuteri 121 complexed with an isomalto-maltopentasaccharide 分子名称: ACETATE ION, CALCIUM ION, Inactive glucansucrase, ... 著者 Pijning, T, Dijkstra, B.W, Bai, Y, Gangoiti-Munecas, J, Dijkhuizen, L. 登録日 2016-04-13 公開日 2017-01-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of 4,6-alpha-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from alpha-Amylases in Oral Bacteria. Structure, 25, 2017
1W7L	Crystal structure of human kynurenine aminotransferase I 分子名称: KYNURENINE--OXOGLUTARATE TRANSAMINASE I, PYRIDOXAL-5'-PHOSPHATE 著者 Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M. 登録日 2004-09-06 公開日 2004-09-08 最終更新日 2015-12-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of Human Kynurenine Aminotransferase I J.Biol.Chem., 279, 2004
1W7N	Crystal structure of human kynurenine aminotransferase I in PMP form 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, KYNURENINE--OXOGLUTARATE TRANSAMINASE I 著者 Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M. 登録日 2004-09-06 公開日 2004-09-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Human Kynurenine Aminotransferase I J.Biol.Chem., 279, 2004
1Q3J	Solution structure of ALO3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus 分子名称: ALO3 著者 Barbault, F, Landon, C, Guenneugues, M, Meyer, J.P, Schott, V, Dimarrcq, J.L, Vovelle, F. 登録日 2003-07-30 公開日 2003-12-23 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Solution structure of Alo-3: a new knottin-type antifungal peptide from the insect Acrocinus longimanus. Biochemistry, 42, 2003
6RL5	The first crystal structure of the DABA aminotransferase EctB in the ectoine biosynthesis pathway of the model organism Chromohalobacter salexigens DSM 3034 分子名称: Diaminobutyrate--2-oxoglutarate transaminase, PYRIDOXAL-5'-PHOSPHATE 著者 Hillier, H.T, Altermark, B, Leiros, I. 登録日 2019-05-01 公開日 2020-03-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The crystal structure of the tetrameric DABA-aminotransferase EctB, a rate-limiting enzyme in the ectoine biosynthesis pathway. Febs J., 287, 2020
1W7M	Crystal structure of human kynurenine aminotransferase I in complex with L-Phe 分子名称: KYNURENINE--OXOGLUTARATE TRANSAMINASE I, PHENYLALANINE, PYRIDOXAL-5'-PHOSPHATE 著者 Rossi, F, Han, Q, Li, J, Li, J, Rizzi, M. 登録日 2004-09-06 公開日 2004-09-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Human Kynurenine Aminotransferase I J.Biol.Chem., 279, 2004
1WCT	A NOVEL CONOTOXIN FROM CONUS TEXTILE WITH UNUSUAL POST-TRANSLATIONAL MODIFICATIONS REDUCES PRESYNAPTIC CALCIUM INFLUX, NMR, 1 STRUCTURE, GLYCOSYLATED PROTEIN 分子名称: OMEGAC-TXIX, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose 著者 Rigby, A.C, Hambe, B, Czerwiec, E, Baleja, J.D, Furie, B.C, Furie, B, Stenflo, J. 登録日 1998-12-18 公開日 1999-06-08 最終更新日 2020-07-29 実験手法 SOLUTION NMR 主引用文献 A conotoxin from Conus textile with unusual posttranslational modifications reduces presynaptic Ca2+ influx. Proc.Natl.Acad.Sci.USA, 96, 1999
2ZC0	Crystal structure of an archaeal alanine:glyoxylate aminotransferase 分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Alanine glyoxylate transaminase, IMIDAZOLE, ... 著者 Sakuraba, H, Yoneda, K, Tsuge, H, Ohshima, T. 登録日 2007-10-31 公開日 2008-06-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of an archaeal alanine:glyoxylate aminotransferase Acta Crystallogr.,Sect.D, 64, 2008
4WLH	High resolution crystal structure of human kynurenine aminotransferase-I bound to PLP cofactor 分子名称: Kynurenine--oxoglutarate transaminase 1 著者 Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. 登録日 2014-10-07 公開日 2014-12-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci., 26, 2017
5YHV	Crystal structure of an aminotransferase from Mycobacterium tuberculosis 分子名称: 2-OXOGLUTARIC ACID, Aminotransferase, GLUTAMIC ACID, ... 著者 Saroj, D.C, Biswal, B.K. 登録日 2017-09-30 公開日 2018-10-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of an aminotransferase from Mycobacterium tuberculosis To Be Published
1WRV	Crystal Structure of T.th.HB8 Branched-Chain Amino Acid Aminotransferase 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Branched-Chain Amino Acid Aminotransferase, CHLORIDE ION, ... 著者 Goto, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-10-27 公開日 2005-10-18 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of T.th.HB8 Branched-Chain Amino Acid Aminotransferase TO BE PUBLISHED
6VWU	X-ray structure of ALKS 4230, a fusion of circularly permuted human Interleukin-2 and Interleukin-2 Receptor alpha 分子名称: Interleukin-2,Interleukin-2 receptor subunit alpha 著者 Losey, H.C. 登録日 2020-02-20 公開日 2020-04-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy. J Immunother Cancer, 8, 2020
4PLK	Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody 8G12 分子名称: 8G12 heavy chain, 8G12 light chain, Capsid protein 著者 Tang, X.H, Li, S.W, Sivaraman, J. 登録日 2014-05-18 公開日 2015-04-08 最終更新日 2015-05-13 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody Cell Res., 25, 2015
6J8E	Human Nav1.2-beta2-KIIIA ternary complex 分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pan, X, Li, Z, Huang, X, Huang, G, Yan, N. 登録日 2019-01-18 公開日 2019-02-27 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for pore blockade of human Na+channel Nav1.2 by the mu-conotoxin KIIIA. Science, 363, 2019
1EDM	EPIDERMAL GROWTH FACTOR-LIKE DOMAIN FROM HUMAN FACTOR IX 分子名称: CALCIUM ION, FACTOR IX 著者 Rao, Z, Handford, P, Mayhew, M, Knott, V, Brownlee, G.G, Stuart, D. 登録日 1996-03-21 公開日 1996-10-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The structure of a Ca(2+)-binding epidermal growth factor-like domain: its role in protein-protein interactions. Cell(Cambridge,Mass.), 82, 1995
6TEI	Crystal structure of human protein kinase CK2alpha (CSNK2A1 gene product) in complex with the 2-aminothiazole-type inhibitor 17 分子名称: 3-[(4-pyridin-2-yl-1,3-thiazol-2-yl)amino]benzoic acid, Casein kinase II subunit alpha, SULFATE ION 著者 Niefind, K, Lindenblatt, D, Jose, J, Applegate, V.M, Nickelsen, A. 登録日 2019-11-12 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.756 Å) 主引用文献 Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2-Aminothiazole Compounds on Protein Kinase CK2. J.Med.Chem., 63, 2020
6MM4	Solution NMR Structure of Engineered Cystine Knot Protein 2.5F 分子名称: Engineered Cystine Knot Protein 2.5F 著者 Cochran, F.V, Cochran, J.R. 登録日 2018-09-29 公開日 2019-10-02 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of Engineered Cystine Knot Protein 2.5F To be published
6NST	Crystal structure of branched chain amino acid aminotransferase from Pseudomonas aeruginosa 分子名称: Branched-chain-amino-acid aminotransferase, SULFATE ION 著者 Chang, C, Skarina, T, Savshenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2019-01-25 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.136 Å) 主引用文献 Crystal structure of branched chain amino acid aminotransferase from Pseudomonas aeruginosa To Be Published

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