7AIA
| Complex of human GDAP1 with hexadecanedioic acid | 分子名称: | ETHANOL, GLYCEROL, Ganglioside-induced differentiation-associated protein 1, ... | 著者 | Nguyen, G.T.T, Sutinen, A, Kursula, P. | 登録日 | 2020-09-26 | 公開日 | 2021-02-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations. Front Mol Biosci, 7, 2020
|
|
4P92
| Crystal structure of dienelactone hydrolase C123S mutant at 1.65 A resolution | 分子名称: | Carboxymethylenebutenolidase, SULFATE ION | 著者 | Porter, J.L, Carr, P.D, Collyer, C.A, Ollis, D.L. | 登録日 | 2014-04-02 | 公開日 | 2014-07-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystallization of dienelactone hydrolase in two space groups: structural changes caused by crystal packing. Acta Crystallogr.,Sect.F, 70, 2014
|
|
5HWV
| |
4PDN
| Crystal structure of E. coli YfcM | 分子名称: | MAGNESIUM ION, Uncharacterized protein | 著者 | Kobayashi, K, Ishii, R, Ishitani, R, Nureki, O. | 登録日 | 2014-04-19 | 公開日 | 2015-03-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.448 Å) | 主引用文献 | The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation. Nucleic Acids Res., 42, 2014
|
|
4PHM
| The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids | 分子名称: | 3-(5-bromo-1H-indol-3-yl)-2-thioxopropanoic acid, CALCIUM ION, Calpain small subunit 1 | 著者 | Rizkallah, P.J, Allemann, R.K, Adams, S.E, Miller, D.J, Hallett, M.B. | 登録日 | 2014-05-06 | 公開日 | 2014-08-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids. J.Struct.Biol., 187, 2014
|
|
5HYU
| |
4PGW
| |
7AQE
| Structure of SARS-CoV-2 Main Protease bound to UNC-2327 | 分子名称: | 3C-like proteinase, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Guenther, S, Reinke, P, Meents, A. | 登録日 | 2020-10-21 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease. Science, 372, 2021
|
|
4PKN
| Crystal structure of the football-shaped GroEL-GroES2-(ADPBeFx)14 complex containing substrate Rubisco | 分子名称: | 10 kDa chaperonin, 60 kDa chaperonin, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Fei, X, Ye, X, Laronde-Leblanc, N, Lorimer, G.H. | 登録日 | 2014-05-15 | 公開日 | 2014-08-20 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.66 Å) | 主引用文献 | Formation and structures of GroEL:GroES2 chaperonin footballs, the protein-folding functional form. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4P16
| Crystal structure of the papain-like protease of Middle-East Respiratory Syndrome coronavirus | 分子名称: | ORF1a, ZINC ION | 著者 | Lei, J, Mesters, J.R, Ma, Q, Hilgenfeld, R. | 登録日 | 2014-02-25 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features. Antiviral Res., 109C, 2014
|
|
5HWI
| Crystal structure of selenomethionine labelled gama glutamyl cyclotransferease specific to glutathione from yeast | 分子名称: | GLYCEROL, Glutathione-specific gamma-glutamylcyclotransferase, SUCCINIC ACID | 著者 | Kaur, A, Gautam, R, Srivastava, R, Chandel, A, Kumar, A, Karthikeyan, S, Bachhawat, A.K. | 登録日 | 2016-01-29 | 公開日 | 2016-12-14 | 最終更新日 | 2017-01-25 | 実験手法 | X-RAY DIFFRACTION (1.755 Å) | 主引用文献 | ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione J. Biol. Chem., 292, 2017
|
|
7B6B
| The carbohydrate binding module family 48 (CBM48) and carboxy-terminal carbohydrate esterase family 1 (CE1) domains of the multidomain esterase DmCE1B from Dysgonomonas mossii in complex with methyl ferulate | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Carbohydrate Esterase family 1 protein with an N-terminal carbohydrate binding module family 48, ... | 著者 | Mazurkewich, S, Kmezik, C, Branden, G, Larsbrink, J. | 登録日 | 2020-12-07 | 公開日 | 2021-03-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | A polysaccharide utilization locus from the gut bacterium Dysgonomonas mossii encodes functionally distinct carbohydrate esterases. J.Biol.Chem., 296, 2021
|
|
7AEL
| alpha 1-antitrypsin (C232S) complexed with GSK716 | 分子名称: | Alpha-1-antitrypsin, SULFATE ION, ~{N}-[(1~{S},2~{R})-1-(3-fluoranyl-2-methyl-phenyl)-1-oxidanyl-pentan-2-yl]-2-oxidanylidene-1,3-dihydroindole-4-carboxamide | 著者 | Chung, C. | 登録日 | 2020-09-17 | 公開日 | 2021-03-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Development of a small molecule that corrects misfolding and increases secretion of Z alpha 1 -antitrypsin. Embo Mol Med, 13, 2021
|
|
4P1X
| Crystal structure of staphylococcal LUK prepore | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Gamma-hemolysin component B, Gamma-hemolysin component C | 著者 | Yamashita, D, Tanaka, Y, Tanaka, I, Yao, M. | 登録日 | 2014-02-28 | 公開日 | 2014-10-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis of transmembrane beta-barrel formation of staphylococcal pore-forming toxins. Nat Commun, 5, 2014
|
|
7AVR
| The tetrameric structure of haloalkane dehalogenase DpaA from Paraglaciecola agarilytica NO2 | 分子名称: | CHLORIDE ION, Haloalkane dehalogenase 1 | 著者 | Mazur, A, Kolenko, P, Prudnikova, T, Grinkevich, P, Kuta Smatanova, I. | 登録日 | 2020-11-05 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The tetrameric structure of the novel haloalkane dehalogenase DpaA from Paraglaciecola agarilytica NO2. Acta Crystallogr D Struct Biol, 77, 2021
|
|
7B1H
| |
7B7E
| Room temperature X-ray structure of perdeuterated PLL lectin | 分子名称: | PLL lectin | 著者 | Gajdos, L, Blakeley, M.P, Kumar, A, Wimmerova, M, Haertlein, M, Forsyth, V.T, Imberty, A, Devos, J.M. | 登録日 | 2020-12-10 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Visualization of hydrogen atoms in a perdeuterated lectin-fucose complex reveals key details of protein-carbohydrate interactions. Structure, 29, 2021
|
|
4P4T
| GDP-bound stalkless-MxA | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Interferon-induced GTP-binding protein Mx1, SULFATE ION | 著者 | Rennie, M.L, McKelvie, S.A, Bulloch, E.M, Kingston, R.L. | 登録日 | 2014-03-13 | 公開日 | 2014-10-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Transient Dimerization of Human MxA Promotes GTP Hydrolysis, Resulting in a Mechanical Power Stroke. Structure, 22, 2014
|
|
7B1J
| |
4P3R
| Cryogenic WT DHFR, time-averaged ensemble | 分子名称: | Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Keedy, D.A, van den Bedem, H, Fraser, J.S. | 登録日 | 2014-03-10 | 公開日 | 2014-05-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR. Structure, 22, 2014
|
|
7AGX
| Apo-state type 3 secretion system export apparatus complex from Salmonella enterica typhimurium | 分子名称: | Protein PrgI, Protein PrgJ, Surface presentation of antigens protein SpaP, ... | 著者 | Goessweiner-Mohr, N, Fahrenkamp, D, Miletic, S, Wald, J, Marlovits, T. | 登録日 | 2020-09-23 | 公開日 | 2021-03-17 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation. Nat Commun, 12, 2021
|
|
4PTD
| PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT D274N | 分子名称: | PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C | 著者 | Heinz, D.W. | 登録日 | 1997-07-18 | 公開日 | 1998-01-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis. Biochemistry, 36, 1997
|
|
7AWX
| Structure of the FKBP51FK1 domain in complex with the macrocyclic SAFit analogue 55 | 分子名称: | Macrocyclic SAFit analogue 55, Peptidyl-prolyl cis-trans isomerase FKBP5 | 著者 | Bauder, M, Meyners, C, Purder, P, Merz, S, Voll, A, Heymann, T, Hausch, F. | 登録日 | 2020-11-09 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-Based Design of High-Affinity Macrocyclic FKBP51 Inhibitors. J.Med.Chem., 64, 2021
|
|
7B2W
| Torpedo californica acetylcholinesterase complexed with UO2 | 分子名称: | Acetylcholinesterase, URANYL (VI) ION | 著者 | Silman, I, Shnyrov, V.L, Ashani, Y, Roth, E, Nicolas, A, Sussman, J.L, Weiner, L. | 登録日 | 2020-11-28 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif. Protein Sci., 30, 2021
|
|
4P6C
| Structure of ribB complexed with inhibitor 4PEH | 分子名称: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID | 著者 | Islam, Z, Kumar, A, Singh, S, Salmon, L, Karthikeyan, S. | 登録日 | 2014-03-24 | 公開日 | 2015-03-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-butanone-4-phosphate Synthase from Vibrio cholerae. J.Biol.Chem., 290, 2015
|
|