PDB: 225399 件ウェブページステータス検索Chemie searchBIRD

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4GQQ	Human pancreatic alpha-amylase with bound ethyl caffeate 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... 著者 Williams, L.K, Brayer, G.D. 登録日 2012-08-23 公開日 2012-10-24 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Order and disorder: differential structural impacts of myricetin and ethyl caffeate on human amylase, an antidiabetic target. J.Med.Chem., 55, 2012
8AKF	Human Sirt6 in complex with ADP-ribose and fragment 3-aminobenzamide 分子名称: 1,2-ETHANEDIOL, 3-aminobenzamide, CHLORIDE ION, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
4WI3	Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation I253A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region 著者 Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. 登録日 2014-09-25 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
4WI6	Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation N434A 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region 著者 Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. 登録日 2014-09-25 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
8AK6	Human Sirt6 in complex with ADP-ribose and fragment sulfamethoxazole 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AK9	Human Sirt6 in complex with ADP-ribose and fragment Isatin 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
4WJV	Crystal structure of Rsa4 in complex with the Nsa2 binding peptide 分子名称: Maltose-binding periplasmic protein, Ribosome assembly protein 4, Ribosome biogenesis protein NSA2, ... 著者 Holdermann, I, Paternoga, H, Bassler, J, Hurt, E, Sinning, I. 登録日 2014-10-01 公開日 2014-11-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J.Cell Biol., 207, 2014
8AK7	Human Sirt6 in complex with ADP-ribose and fragment 6-O-methylguanine 分子名称: 1,2-ETHANEDIOL, 6-O-methylguanine, CHLORIDE ION, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AKA	Human Sirt6 in complex with ADP-ribose and fragment cis-resveratrol 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
4WSR	The crystal structure of hemagglutinin form A/chicken/New York/14677-13/1998 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin 著者 Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. 登録日 2014-10-28 公開日 2015-02-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes. J.Virol., 89, 2015
8AKE	Human Sirt6 in complex with ADP-ribose and fragment nicotinamide 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NAD-dependent protein deacetylase sirtuin-6, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AK8	Human Sirt6 in complex with ADP-ribose and fragment 4-hydroxybenzamide 分子名称: 4-HYDROXYBENZAMIDE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8AKG	Human Sirt6 in complex with ADP-ribose and fragment 4-amino-6-chlorobenzene-1,3-disulfonamide 分子名称: 1,2-ETHANEDIOL, 4-AMINO-6-CHLOROBENZENE-1,3-DISULFONAMIDE, CHLORIDE ION, ... 著者 You, W, Steegborn, C. 登録日 2022-07-29 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
4X12	JC Polyomavirus genotype 3 VP1 in complex with GD1b oligosaccharide 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein, ... 著者 Stroh, L.J, Stehle, T. 登録日 2014-11-24 公開日 2015-04-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Greater Affinity of JC Polyomavirus Capsid for alpha 2,6-Linked Lactoseries Tetrasaccharide c than for Other Sialylated Glycans Is a Major Determinant of Infectivity. J.Virol., 89, 2015
8BL0	Human Sirt6 in complex with the inhibitor S6023 and ADP-ribose 分子名称: 3-[4-[[5-(2-fluorophenyl)thiophen-2-yl]methyl]piperazin-1-yl]sulfonylbenzenesulfonamide, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 You, W, Steegborn, C. 登録日 2022-11-09 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
8BL1	Human Sirt6 in complex with the inhibitor S6039 and ADP-ribose 分子名称: 2-azanyl-5-[4-[[5-(2-fluorophenyl)thiophen-2-yl]methyl]piperazin-1-yl]sulfonyl-benzenesulfonamide, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 You, W, Steegborn, C. 登録日 2022-11-09 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Development of novel Sirtuin 6 inhibitors and activators based on a protein crystallography-based fragment screen To Be Published
5YST	RanM189D in complex with RanBP1-CRM1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ... 著者 Sun, Q, Zhang, Y. 登録日 2017-11-15 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 RanM189D in complex with RanBP1-CRM1 To Be Published
5YSU	Plumbagin in complex with CRM1-RanM189D-RanBP1 分子名称: (2~{R})-2-methyl-5-oxidanyl-2,3-dihydronaphthalene-1,4-dione, CHLORIDE ION, Exportin-1,Exportin-1, ... 著者 Sun, Q, Zhang, Y. 登録日 2017-11-15 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 RanL182A in complex with RanBP1-CRM1 To Be Published
5YRO	RanL182A in complex with RanBP1-CRM1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ... 著者 Sun, Q, Zhang, Y. 登録日 2017-11-09 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.396 Å) 主引用文献 RanL182A in complex with RanBP1-CRM1 To Be Published
5YTB	RanY197A in complex with RanBP1-CRM1 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Sun, Q, Zhang, Y. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 RanY197A in complex with RanBP1-CRM1 To Be Published
9BOO	Crystal structure of MERS-CoV Nsp5 in complex with PF-07817883 分子名称: 3C-like proteinase nsp5, N-(methoxycarbonyl)-3-methyl-L-valyl-(4R)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-4-(trifluoromethyl)-L-prolinamide 著者 Chen, P, Arutyunova, E, Lemieux, M.J. 登録日 2024-05-05 公開日 2024-08-07 最終更新日 2024-09-18 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A Structural Comparison of Oral SARS-CoV-2 Drug Candidate Ibuzatrelvir Complexed with the Main Protease (M pro ) of SARS-CoV-2 and MERS-CoV. Jacs Au, 4, 2024
9D2C	Crystal Structure of Tungbindin Treated with Proteinase K 分子名称: MOLYBDATE ION, Molybdenum-pterin binding domain-containing protein 著者 Zhou, D, Chen, L, Rose, J.P, Wang, B.C. 登録日 2024-08-08 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Crystal structure of Tungbindin treated with proteinase K To Be Published
4V6X	Structure of the human 80S ribosome 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R. 登録日 2013-02-27 公開日 2014-07-09 最終更新日 2023-02-01 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Structures of the human and Drosophila 80S ribosome. Nature, 497, 2013
9GDK	Jumonji domain-containing protein 1C with crystallization epitope mutations L2440Y:G2444H 分子名称: Probable JmjC domain-containing histone demethylation protein 2C 著者 Fairhead, M, Strain-Damerell, C, Ye, M, Mackinnon, S.R, Pinkas, D, MacLean, E.M, Koekemoer, L, Damerell, D, Krojer, T, Arrowsmith, C.H, Edwards, A, Bountra, C, Yue, W, Burgess-Brown, N, Marsden, B, von Delft, F, Structural Genomics Consortium (SGC) 登録日 2024-08-05 公開日 2024-08-21 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 A fast, parallel method for efficiently exploring crystallization behaviour of large numbers of protein variants To Be Published
9FZK	SARS CoV-2 nsp10 in complex with theExoN domain from nsp14 分子名称: Guanine-N7 methyltransferase nsp14, Non-structural protein 11, ZINC ION 著者 Fisher, S.Z. 登録日 2024-07-05 公開日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 SARS CoV-2 nsp10 in complex with theExoN domain from nsp14 To Be Published

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