PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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1N5K	CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE CRYSTALLIZED IN SODIUM MALONATE (RESOLUTION 2.1 A) 分子名称: ACETATE ION, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, ... 著者 Fioravanti, E, Haouz, A, Ursby, T, Munier-Lehmann, H, Delarue, M, Bourgeois, D. 登録日 2002-11-06 公開日 2003-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the Reaction Pathway J.Mol.Biol., 375, 2003
1N5L	CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS THYMIDYLATE KINASE CRYSTALLIZED IN SODIUM MALONATE, AFTER CATALYSIS IN THE CRYSTAL (2.3 A RESOLUTION) 分子名称: ACETATE ION, DIPHOSPHATE, MAGNESIUM ION, ... 著者 Fioravanti, E, Haouz, A, Ursby, T, Munier-Lehmann, H, Delarue, M, Bourgeois, D. 登録日 2002-11-06 公開日 2003-04-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Mycobacterium tuberculosis Thymidylate Kinase: Structural Studies of Intermediates along the Reaction Pathway J.Mol.Biol., 375, 2003
2A4X	Crystal Structure Of Mitomycin C-Binding Protein Complexed with Metal-Free Bleomycin A2 分子名称: BLEOMYCIN A2, Mitomycin-Binding Protein 著者 Danshiitsoodol, N, de Pinho, C.A, Matoba, Y, Kumagai, T, Sugiyama, M. 登録日 2005-06-30 公開日 2006-07-18 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The Mitomycin C (MMC)-binding Protein from MMC-producing Microorganisms Protects from the Lethal Effect of Bleomycin: Crystallographic Analysis to Elucidate the Binding Mode of the Antibiotic to the Protein J.Mol.Biol., 360, 2006
2IPI	Crystal Structure of Aclacinomycin Oxidoreductase 分子名称: Aclacinomycin oxidoreductase (AknOx), FLAVIN-ADENINE DINUCLEOTIDE, METHYL (2S,4R)-2-ETHYL-2,5,7-TRIHYDROXY-6,11-DIOXO-4-{[2,3,6-TRIDEOXY-4-O-{2,6-DIDEOXY-4-O-[(2S,6S)-6-METHYL-5-OXOTETRAHYDRO-2H-PYRAN-2-YL]-ALPHA-D-LYXO-HEXOPYRANOSYL}-3-(DIMETHYLAMINO)-D-RIBO-HEXOPYRANOSYL]OXY}-1,2,3,4,6,11-HEXAHYDROTETRACENE-1-CARBOXYLATE 著者 Sultana, A, Kursula, I, Schneider, G, Alexeev, I, Niemi, J, Mantsala, P. 登録日 2006-10-12 公開日 2007-01-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure determination by multiwavelength anomalous diffraction of aclacinomycin oxidoreductase: indications of multidomain pseudomerohedral twinning. Acta Crystallogr.,Sect.D, 63, 2007
2Y3R	Structure of the tirandamycin-bound FAD-dependent tirandamycin oxidase TamL in P21 space group 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H. 登録日 2010-12-22 公開日 2011-06-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes Nat.Chem, 3, 2011
2Y3S	Structure of the tirandamycine-bound FAD-dependent tirandamycin oxidase TamL in C2 space group 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H. 登録日 2010-12-23 公開日 2011-06-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes Nat.Chem, 3, 2011
2Y4G	Structure of the Tirandamycin-bound FAD-dependent tirandamycin oxidase TamL in P212121 space group 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Carlson, J.C, Li, S, Gunatilleke, S.S, Anzai, Y, Burr, D.A, Podust, L.M, Sherman, D.H. 登録日 2011-01-05 公開日 2011-06-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes Nat.Chem, 3, 2011
5ZON	Histidinol phosphate phosphatase from Mycobacterium tuberculosis 分子名称: GLYCEROL, Histidinol-phosphatase, PHOSPHATE ION, ... 著者 Jha, B, Kumar, D, Biswal, B.K. 登録日 2018-04-13 公開日 2018-05-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Identification and structural characterization of a histidinol phosphate phosphatase from Mycobacterium tuberculosis J. Biol. Chem., 293, 2018
7K0A	Puromycin N-acetyltransferase in complex with acetylated puromycin and CoA 分子名称: 1,2-ETHANEDIOL, COENZYME A, DI(HYDROXYETHYL)ETHER, ... 著者 Peat, T.S, Caputo, A.T, Newman, J, Adams, T.E. 登録日 2020-09-03 公開日 2021-03-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins. Sci Rep, 11, 2021
5UHU	Solution conformation of cytochrome P450 MycG with mycinamicin IV bound 分子名称: MYCINAMICIN IV, Mycinamicin IV hydroxylase/epoxidase, PROTOPORPHYRIN IX CONTAINING FE 著者 Pochapsky, T.C, Tietz, D.R. 登録日 2017-01-12 公開日 2017-08-23 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution Conformations and Dynamics of Substrate-Bound Cytochrome P450 MycG. Biochemistry, 56, 2017
8PBY	Single particle cryo-EM of the P140-P110 heterodimer with an alternative conformation in the P140 stalk of Mycoplasma genitalium at a resolution of 3.7 Angstrom. 分子名称: Adhesin P1, Mgp-operon protein 3 著者 Sprankel, L, Scheffer, M.P, Frangakis, A.S. 登録日 2023-06-09 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-electron tomography reveals the binding and release states of the major adhesion complex from Mycoplasma genitalium. Plos Pathog., 19, 2023
8PBX	Single particle cryo-EM of the P140-P110 heterodimer of Mycoplasma genitalium at 3.3 Angstrom resolution. 分子名称: Adhesin P1, Mgp-operon protein 3 著者 Sprankel, L, Scheffer, M.P, Frangakis, A.S. 登録日 2023-06-09 公開日 2023-11-01 最終更新日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-electron tomography reveals the binding and release states of the major adhesion complex from Mycoplasma genitalium. Plos Pathog., 19, 2023
7FE6	AvmM Catalyzes Macrocyclization in Alchivemycin A Biosynthesis 分子名称: Alchivemycin A, AvmM, CHLORIDE ION 著者 Zhang, B, Ge, H.M. 登録日 2021-07-19 公開日 2021-09-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 AvmM catalyses macrocyclization through dehydration/Michael-type addition in alchivemycin A biosynthesis. Nat Commun, 13, 2022
5I4Z	Structure of apo OmoMYC 分子名称: CHLORIDE ION, GLYCEROL, Myc proto-oncogene protein, ... 著者 Koelmel, W, Jung, L.A, Kuper, J, Eilers, M, Kisker, C. 登録日 2016-02-13 公開日 2016-10-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors. Oncogene, 36, 2017
5I50	Structure of OmoMYC bound to double-stranded DNA 分子名称: DNA (5'-D(P*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*CP*TP*AP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*CP*GP*GP*GP*TP*G)-3'), Myc proto-oncogene protein 著者 Koelmel, W, Jung, L.A, Kuper, J, Eilers, M, Kisker, C. 登録日 2016-02-13 公開日 2016-10-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.701 Å) 主引用文献 OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors. Oncogene, 36, 2017
8HCR	Cryo-EM structure of the Mycobacterium tuberculosis cytochrome bcc:aa3 supercomplex and a novel inhibitor targeting subunit cytochrome cI 分子名称: CYTOCHROME AA3 SUBUNIT CtaC, CYTOCHROME AA3 SUBUNIT CtaJ, Cytochrome bc1 complex Rieske iron-sulfur subunit, ... 著者 Mathiyazakan, V, Gruber, G. 登録日 2022-11-02 公開日 2023-05-03 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY 主引用文献 Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosi s Cytochrome bcc : aa 3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome c I. Antimicrob.Agents Chemother., 67, 2023
8UFE	Multidrug efflux pump EfpA from mycobacterium smegmatis 分子名称: Integral membrane efflux protein EfpA, PHOSPHATIDYLETHANOLAMINE 著者 Wang, S, Liao, M. 登録日 2023-10-04 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structures of the Mycobacterium tuberculosis efflux pump EfpA reveal the mechanisms of transport and inhibition. Nat Commun, 15, 2024
6O6O	Structure of the regulator FasR from Mycobacterium tuberculosis 分子名称: MYRISTIC ACID, TetR family transcriptional regulator 著者 Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. 登録日 2019-03-07 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine. Nat Commun, 11, 2020
6O6N	Structure of the regulator FasR from Mycobacterium tuberculosis in complex with C20-CoA 分子名称: Arachinoyl-CoA, CHLORIDE ION, TetR family transcriptional regulator 著者 Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. 登録日 2019-03-07 公開日 2020-03-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine. Nat Commun, 11, 2020
6O6P	Structure of the regulator FasR from Mycobacterium tuberculosis in complex with DNA 分子名称: DNA-forward, DNA-reverse, TetR family transcriptional regulator 著者 Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. 登録日 2019-03-07 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.851 Å) 主引用文献 Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine. Nat Commun, 11, 2020
7AGR	Structure of the M624V-S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis soaked with MethylMalonyl Coenzyme A 分子名称: 1,2-ETHANEDIOL, Mycocerosic acid synthase 著者 Brison, Y, Mourey, L, Maveyraud, L. 登録日 2020-09-23 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
7AGS	Structure of the AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis acylated MethylMalonyl-CoenzymeA 分子名称: METHYLMALONIC ACID, Mycocerosic acid synthase 著者 Brison, Y, Mourey, L, Maveyraud, L. 登録日 2020-09-23 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
7AGP	Structure of the AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis 分子名称: 1,2-ETHANEDIOL, Mycocerosic acid synthase 著者 Brison, Y, Nahoum, V, Mourey, L, Maveyraud, L. 登録日 2020-09-23 公開日 2020-12-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
7AGQ	Structure of the S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis 分子名称: ACETATE ION, GLYCEROL, Mycocerosic acid synthase 著者 Brison, Y, Mourey, L, Maveyraud, L. 登録日 2020-09-23 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
6CCV	Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Rifampicin 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2018-02-07 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018

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