PDB: 22592 件ウェブページステータス検索Chemie searchBIRD

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7BVH	Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose 分子名称: CALCIUM ION, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, Meromycolate extension acyl carrier protein, ... 著者 Zhao, Y, Zhang, L, Wu, L.J, Wang, Q, Li, J, Besra, G.S, Rao, Z.H. 登録日 2020-04-10 公開日 2020-04-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368, 2020
1XVN	echinomycin (ACGTACGT)2 complex 分子名称: 2-CARBOXYQUINOXALINE, 5'-D(*AP*CP*GP*TP*AP*CP*GP*T)-3', ECHINOMYCIN, ... 著者 Cuesta-Seijo, J.A, Sheldrick, G.M. 登録日 2004-10-28 公開日 2005-04-12 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structures of Complexes between Echinomycin and Duplex DNA. Acta Crystallogr.,Sect.D, 61, 2005
1XVR	echinomycin (CGTACG)2 complex 分子名称: 2-CARBOXYQUINOXALINE, 5'-D(*CP*GP*TP*AP*CP*G)-3', ECHINOMYCIN, ... 著者 Cuesta-Seijo, J.A, Sheldrick, G.M. 登録日 2004-10-28 公開日 2005-04-12 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structures of Complexes between Echinomycin and Duplex DNA. Acta Crystallogr.,Sect.D, 61, 2005
3QYX	Crystal structure of Mycobacterium tuberculosis EspR in complex with a small DNA fragment 分子名称: 5'-D(*A*CP*GP*CP*CP*GP*AP*AP*TP*C)-3', ESX-1 secretion-associated regulator EspR 著者 Blasco, B, Pojer, F, Cole, S.T. 登録日 2011-03-04 公開日 2011-09-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.75 Å) 主引用文献 Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis. Mol.Microbiol., 82, 2011
3R44	Mycobacterium tuberculosis fatty acyl CoA synthetase 分子名称: HISTIDINE, MALONATE ION, fatty acyl CoA synthetase FADD13 (FATTY-ACYL-CoA SYNTHETASE) 著者 Andersson, C.S, Martinez Molina, D, Hogbom, M. 登録日 2011-03-17 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Mycobacterium tuberculosis Very-Long-Chain Fatty Acyl-CoA Synthetase: Structural Basis for Housing Lipid Substrates Longer than the Enzyme. Structure, 20, 2012
4HIV	Structure of actinomycin D d(ATGCGGCAT) complex 分子名称: ACTINOMYCIN D, DNA (5'-D(*AP*TP*GP*CP*GP*GP*CP*AP*T)-3') 著者 Lo, Y.S, Tseng, W.H, Hou, M.H. 登録日 2012-10-12 公開日 2013-05-08 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The structural basis of actinomycin D-binding induces nucleotide flipping out, a sharp bend and a left-handed twist in CGG triplet repeats. Nucleic Acids Res., 41, 2013
3R5L	Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Deazaflavin-dependent nitroreductase 著者 Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayyar, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. 登録日 2011-03-18 公開日 2012-01-18 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
3R5R	Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824, with co-factor F420 分子名称: COENZYME F420, Deazaflavin-dependent nitroreductase 著者 Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayya, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. 登録日 2011-03-19 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.101 Å) 主引用文献 Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
4HAY	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548E,K579Q)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB4	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(537DLTVK541/GLCEQ)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAZ	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(R543S,K548E,K579Q)-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
3R1F	Crystal structure of a key regulator of virulence in Mycobacterium tuberculosis 分子名称: ESX-1 secretion-associated regulator EspR 著者 Rosenberg, O.S, Dovey, C, Finer-Moore, J, Stroud, R.M, Cox, J.S. 登録日 2011-03-10 公開日 2011-08-03 最終更新日 2011-08-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 EspR, a key regulator of Mycobacterium tuberculosis virulence, adopts a unique dimeric structure among helix-turn-helix proteins. Proc.Natl.Acad.Sci.USA, 108, 2011
4HAW	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K548A)-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HAT	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HB0	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1(K541Q,K542Q,R543S,K545Q,K548Q,K579Q)-Ran-RanBP1 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
3R5P	Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824 分子名称: Deazaflavin-dependent nitroreductase, SULFATE ION 著者 Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayya, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. 登録日 2011-03-19 公開日 2012-01-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
3QWG	Crystal structure of EspRdelta10, C-terminal 10 amino acids deletion mutant of EspR transcription factor from Mycobacterium tuberculosis 分子名称: ESX-1 secretion-associated regulator EspR 著者 Blasco, B, Pojer, F, Cole, S.T. 登録日 2011-02-28 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis. Mol.Microbiol., 82, 2011
3TZ6	Crystal structure of Aspartate semialdehyde dehydrogenase Complexed With inhibitor SMCS (CYS) And Phosphate From Mycobacterium tuberculosis H37Rv 分子名称: Aspartate-semialdehyde dehydrogenase, CYSTEINE, GLYCEROL, ... 著者 Vyas, R, Tewari, R, Weiss, M.S, Karthikeyan, S. 登録日 2011-09-27 公開日 2012-05-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv Acta Crystallogr.,Sect.D, 68, 2012
3R5W	Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824, with co-factor F420 分子名称: COENZYME F420, Deazaflavin-dependent nitroreductase 著者 Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayya, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. 登録日 2011-03-20 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.786 Å) 主引用文献 Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
3UC5	Phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis complexed with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Phosphopantetheine adenylyltransferase 著者 Timofeev, V.I, Smirnova, E.A, Chupova, L.A, Esipov, R.S, Kuranova, I.P. 登録日 2011-10-26 公開日 2012-11-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 X-ray study of the conformational changes in the molecule of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis during the catalyzed reaction. Acta Crystallogr.,Sect.D, 68, 2012
7KIN	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter 分子名称: DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
4OKE	Structure of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo 分子名称: 3'-5' exoribonuclease Rv2179c/MT2234.1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION 著者 Berisio, R, Romano, M. 登録日 2014-01-22 公開日 2014-05-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and Function of RNase AS, a Polyadenylate-Specific Exoribonuclease Affecting Mycobacterial Virulence In Vivo Structure, 22, 2014
6C06	Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. 登録日 2017-12-27 公開日 2018-03-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.15 Å) 主引用文献 Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
6C05	Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. 登録日 2017-12-27 公開日 2018-03-28 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (5.15 Å) 主引用文献 Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
7LHL	cryo-EM structure of Mycobacterium smegmatis Lhr helicase C-terminal domain 分子名称: ATP-dependent DNA helicase 著者 Wang, J, Warren, G.M, Shuman, S, Patel, D.J. 登録日 2021-01-25 公開日 2021-04-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Oligomeric quaternary structure of Escherichia coli and Mycobacterium smegmatis Lhr helicases is nucleated by a novel C-terminal domain composed of five winged-helix modules. Nucleic Acids Res., 49, 2021

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