PDB: 185519 件ウェブページステータス検索Chemie searchBIRD

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4JI0	Crystal Structure of 30S ribosomal subunit from Thermus thermophilus 分子名称: 16S rRNA, MAGNESIUM ION, ZINC ION, ... 著者 Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. 登録日 2013-03-05 公開日 2013-11-06 最終更新日 2013-12-04 実験手法 X-RAY DIFFRACTION (3.492 Å) 主引用文献 The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna, 19, 2013
6Z0R	Crystal structure of SAICAR Synthetase (PurC) from Mycobacterium abscessus in complex with fragment 1 分子名称: 1,2-ETHANEDIOL, 4-azanylpyrimidine-5-carbonitrile, Phosphoribosylaminoimidazole-succinocarboxamide synthase, ... 著者 Thomas, S.E, Charoensutthivarakul, S, Coyne, A.G, Abell, C, Blundell, T.L. 登録日 2020-05-10 公開日 2021-05-19 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.308 Å) 主引用文献 Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach. Acs Infect Dis., 8, 2022
1GR3	Structure of the human collagen X NC1 trimer 分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, COLLAGEN X, ... 著者 Bogin, O, Kvansakul, M, Rom, E, Singer, J, Yayon, A, Hohenester, E. 登録日 2001-12-12 公開日 2002-02-14 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insight Into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X Nc1 Domain Trimer. Structure, 10, 2002
1STA	ACCOMMODATION OF INSERTION MUTATIONS ON THE SURFACE AND IN THE INTERIOR OF STAPHYLOCOCCAL NUCLEASE 分子名称: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE 著者 Keefe, L.J, Quirk, S, Gittis, A, Lattman, E.E. 登録日 1994-01-17 公開日 1994-06-22 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease. Protein Sci., 3, 1994
4QPG	Crystal structure of empty hepatitis A virus 分子名称: CHLORIDE ION, Capsid protein VP0, Capsid protein VP1, ... 著者 Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. 登録日 2014-06-23 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Hepatitis A virus and the origins of picornaviruses. Nature, 517, 2015
8RH1	Trimeric HSV-2F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules. 分子名称: Envelope glycoprotein B, HDIT101 Fab heavy chain, HDIT101 Fab light chain 著者 Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. 登録日 2023-12-14 公開日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus. J.Biomed.Sci., 31, 2024
6ZGK	GLIC pentameric ligand-gated ion channel, pH 3 分子名称: Proton-gated ion channel 著者 Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. 登録日 2020-06-18 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
8RH0	Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT102 Fab molecules. 分子名称: Envelope glycoprotein B, HDIT102 Fab heavy chain 著者 Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. 登録日 2023-12-14 公開日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.44 Å) 主引用文献 Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus. J.Biomed.Sci., 31, 2024
2J9J	Atomic-resolution Crystal Structure of Chemically-Synthesized HIV-1 Protease Complexed with Inhibitor JG-365 分子名称: ACETATE ION, GLYCEROL, INHIBITOR MOLECULE JG365, ... 著者 Malito, E, Shen, Y, Johnson, E.C.B, Tang, W.J. 登録日 2006-11-11 公開日 2007-08-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Insights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with Inhibitors. J.Mol.Biol., 373, 2007
2IZR	Structure of casein kinase gamma 3 in complex with inhibitor 分子名称: CASEIN KINASE I ISOFORM GAMMA-3, CHLORIDE ION, MAGNESIUM ION, ... 著者 Bunkoczi, G, Salah, E, Rellos, P, Das, S, Fedorov, O, Savitsky, P, Debreczeni, J.E, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. 登録日 2006-07-26 公開日 2006-08-01 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Inhibitor Binding by Casein Kinases To be Published
6ZGD	GLIC pentameric ligand-gated ion channel, pH 7 分子名称: Proton-gated ion channel 著者 Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. 登録日 2020-06-18 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
6ZGJ	GLIC pentameric ligand-gated ion channel, pH 5 分子名称: Proton-gated ion channel 著者 Rovsnik, U, Zhuang, Y, Forsberg, B.O, Carroni, M, Yvonnesdotter, L, Howard, R.J, Lindahl, E. 登録日 2020-06-18 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations. Life Sci Alliance, 4, 2021
8DK4	Peroxisome proliferator-activated receptor gamma in complex with VSP-51-2 分子名称: 5-(benzylcarbamoyl)-1-[(4-chloro-3-fluorophenyl)methyl]-1H-indole-2-carboxylic acid, Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 著者 Ma, L, Zhou, X.E, Suino-Powell, K, Hou, N, Zhou, Z, Luo, J, Xu, H.E, Yi, W. 登録日 2022-07-02 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Identification of VSP-51-2 as the Novel and Safe PPAR gamma Modulator: Structure-Based Design, Biological Validation and Crystal Analysis To Be Published
2I3C	Crystal Structure of an Aspartoacylase from Homo Sapiens 分子名称: Aspartoacylase, PHOSPHATE ION, ZINC ION 著者 Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Mccoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-08-17 公開日 2006-08-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of aspartoacylase, the brain enzyme impaired in Canavan disease. Proc.Natl.Acad.Sci.Usa, 104, 2007
4X59	Anthranilate phosphoribosyltransferase variant P180A from Mycobacterium tuberculosis in complex with PRPP and Mg 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, GLYCEROL, ... 著者 Cookson, T.V.M, Evans, G.L, Parker, E.J, Lott, J.S. 登録日 2014-12-04 公開日 2015-11-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site. Biochemistry, 54, 2015
6AQB	Structure of the SH3 domain of MLK3 bound to peptide generated from phage display 分子名称: 1,2-ETHANEDIOL, Chimera protein of MLK3-SH3 and MIP (E.C.2.7.11.25), PHOSPHATE ION 著者 Kall, S.K, Lavie, A. 登録日 2017-08-19 公開日 2018-07-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3. J. Biol. Chem., 293, 2018
1H0W	Human cyclin dependent protein kinase 2 in complex with the inhibitor 2-Amino-6-[cyclohex-3-enyl]methoxypurine 分子名称: 1-AMINO-6-CYCLOHEX-3-ENYLMETHYLOXYPURINE, CELL DIVISION PROTEIN KINASE 2 著者 Gibson, A.E, Arris, C.E, Bentley, J, Boyle, F.T, Curtin, N.J, Davies, T.G, Endicott, J.A, Golding, B.T, Grant, S, Griffin, R.J, Jewsbury, P, Johnson, L.N, Mesguiche, V, Newell, D.R, Noble, M.E.M, Tucker, J.A, Whitfield, H.J. 登録日 2002-06-27 公開日 2003-06-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives J.Med.Chem., 45, 2002
8RGZ	Trimeric HSV-1F gB ectodomain in postfusion conformation with three bound HDIT101 Fab molecules. 分子名称: Envelope glycoprotein B, HDIT101 Fab heavy chain, HDIT101 Fab light chain 著者 Kalbermatter, D, Seyfizadeh, N, Imhof, T, Ries, M, Mueller, C, Jenner, L, Blumenschein, E, Yendrzheyevskiy, A, Moog, K, Eckert, D, Engel, R, Diebolder, P, Chami, M, Krauss, J, Schaller, T, Arndt, M. 登録日 2023-12-14 公開日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Development of a highly effective combination monoclonal antibody therapy against Herpes simplex virus. J.Biomed.Sci., 31, 2024
8E9A	Crystal structure of AsfvPolX in complex with 10-23 DNAzyme and Mg 分子名称: DNA/RNA (52-MER), MAGNESIUM ION, Repair DNA polymerase X, ... 著者 Cramer, E.R, Robart, A.R, Kaya, A.I. 登録日 2022-08-26 公開日 2023-06-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Structure of a 10-23 deoxyribozyme exhibiting a homodimer conformation. Commun Chem, 6, 2023
4WX2	Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with two F6F molecules in the alpha-site and one F6F molecule in the beta-site 分子名称: 1,2-ETHANEDIOL, 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Hilario, E, Caulkins, B.G, Young, R.P, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. 登録日 2014-11-13 公開日 2015-11-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water. Biochim.Biophys.Acta, 1864, 2016
6SLZ	Crystal structure of human ROR gamma LBD in complex with a (quinolinoxymethyl)benzamide inverse agonist 分子名称: (2~{S})-1-[2,4-bis(chloranyl)-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]carbonyl-~{N}-methyl-pyrrolidine-2-carboxamide, Nuclear receptor ROR-gamma 著者 Amaudrut, J, Argiriadi, M.A, Barth, M, Breinlinger, E.C, Calderwood, D.J, Cusack, K.P, Kort, M.E, Montalbetti, C, Potin, D, Poupardin, O, Spitzer, L. 登録日 2019-08-21 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of human ROR gamma LBD in complex with a (quinolinoxymethyl)benzamide inverse agonist To Be Published
4WYL	Mutant K18E of 3D polymerase from Foot-and-Moth Disease Virus 分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ... 著者 Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E. 登録日 2014-11-17 公開日 2015-05-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. J.Virol., 89, 2015
6AW0	Crystal structure of CEACAM3 L44Q 分子名称: CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 3, GLYCEROL, ... 著者 Bonsor, D.A, Sundberg, E.J. 登録日 2017-09-05 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 TheHelicobacter pyloriadhesin protein HopQ exploits the dimer interface of human CEACAMs to facilitate translocation of the oncoprotein CagA. EMBO J., 37, 2018
1HBI	CRYSTAL STRUCTURE OF OXYGENATED SCAPHARCA DIMERIC HEMOGLOBIN AT 1.7 ANGSTROMS RESOLUTION 分子名称: HEMOGLOBIN (OXY), OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE 著者 Royer Junior, W.E, Condon, P.J. 登録日 1994-06-22 公開日 1994-10-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of oxygenated Scapharca dimeric hemoglobin at 1.7-A resolution. J.Biol.Chem., 269, 1994
5FMV	Crystal structure of human CD45 extracellular region, domains d1-d4 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, SULFATE ION 著者 Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. 登録日 2015-11-09 公開日 2016-03-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'. Nat.Immunol., 17, 2016

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