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3CVT
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Crystal Structure of an AlkA Host/Guest Complex 8oxoGuanine:Cytosine Base Pair
分子名称: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*(8OG)P*DAP*DGP*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DCP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2008-04-19
公開日2008-09-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
3D0E
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Crystal structure of human Akt2 in complex with GSK690693
分子名称: 4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3-yn-2-ol, RAC-beta serine/threonine-protein kinase
著者Concha, N.O, Smallwood, A.
登録日2008-05-01
公開日2008-10-21
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase.
J.Med.Chem., 51, 2008
3D3D
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Bacteriophage lambda lysozyme complexed with a chitohexasaccharide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme, SULFATE ION
著者Leung, A.K.W, Berghuis, A.M.
登録日2008-05-09
公開日2008-09-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the lytic transglycosylase from bacteriophage lambda in complex with hexa-N-acetylchitohexaose
Biochemistry, 40, 2001
3CTD
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Crystal structure of a putative AAA family ATPase from Prochlorococcus marinus subsp. pastoris
分子名称: Putative ATPase, AAA family
著者Bonanno, J.B, Rutter, M, Bain, K.T, Lau, C, Ozyurt, S, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-04-11
公開日2008-04-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a putative AAA family ATPase from Prochlorococcus marinus subsp. pastoris.
To be Published
3D4N
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Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase (HSD1) in Complex with Sulfonamide Inhibitor
分子名称: 1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Wang, Z, Liu, J, Sudom, A, Walker, N.P.
登録日2008-05-14
公開日2008-07-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of Novel, Potent Benzamide Inhibitors of 11beta-Hydroxysteroid Dehydrogenase Type 1 (11beta-HSD1) Exhibiting Oral Activity in an Enzyme Inhibition ex Vivo Model
J.Med.Chem., 51, 2008
3D51
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GOLGI MANNOSIDASE II complex with gluco-hydroxyiminolactam
分子名称: (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, (4R)-2-METHYLPENTANE-2,4-DIOL, Alpha-mannosidase 2, ...
著者Kuntz, D.A, Tarling, C.A, Withers, S.G, Rose, D.R.
登録日2008-05-15
公開日2008-08-05
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structural analysis of Golgi alpha-mannosidase II inhibitors identified from a focused glycosidase inhibitor screen.
Biochemistry, 47, 2008
3CGY
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Crystal Structure of Salmonella Sensor Kinase PhoQ catalytic domain in complex with radicicol
分子名称: RADICICOL, Virulence sensor histidine kinase phoQ
著者Guarnieri, M.T, Zhang, L, Shen, J, Zhao, R.
登録日2008-03-06
公開日2008-05-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Hsp90 inhibitor radicicol interacts with the ATP-binding pocket of bacterial sensor kinase PhoQ.
J.Mol.Biol., 379, 2008
3CIB
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Structure of BACE Bound to SCH727596
分子名称: Beta-secretase 1, D(-)-TARTARIC ACID, N'-[(1S,2R)-2-[(2R,4S)-4-benzylpiperidin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide
著者Strickland, C, Cumming, J.
登録日2008-03-11
公開日2008-06-10
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors
Bioorg.Med.Chem.Lett., 18, 2008
3COC
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Crystal Structure of D115A mutant of Bacteriorhodopsin
分子名称: Bacteriorhodopsin, RETINAL
著者Joh, N.H, Faham, S, Bowie, J.U.
登録日2008-03-27
公開日2008-04-08
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins.
Nature, 453, 2008
3CMA
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The structure of CCA and CCA-Phe-Cap-Bio bound to the large ribosomal subunit of Haloarcula marismortui
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Simonovic, M, Steitz, T.A.
登録日2008-03-21
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3CQ0
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Crystal Structure of TAL2_YEAST
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Putative transaldolase YGR043C, ...
著者Huang, H, Niu, L, Teng, M.
登録日2008-04-01
公開日2009-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure and identification of NQM1/YGR043C, a transaldolase from Saccharomyces cerevisiae
Proteins, 73, 2008
3CQL
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Crystal Structure of GH family 19 chitinase from Carica papaya
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Endochitinase, ...
著者Huet, J, Rucktoa, P, Clantin, B, Azarkan, M, Looze, Y, Villeret, V, Wintjens, R.
登録日2008-04-03
公開日2008-08-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray Structure of Papaya Chitinase Reveals the Substrate Binding Mode of Glycosyl Hydrolase Family 19 Chitinases.
Biochemistry, 47, 2008
3CVB
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Regulation of Protein Function: Crystal Packing Interfaces and Conformational Dimerization
分子名称: COPPER (I) ION, Plastocyanin
著者Crowley, P.B, Matias, P.M, Mi, H, Firbank, S.J, Banfield, M.J, Dennison, C.
登録日2008-04-18
公開日2008-07-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Regulation of protein function: crystal packing interfaces and conformational dimerization.
Biochemistry, 47, 2008
3CT4
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Structure of Dha-kinase subunit DhaK from L. Lactis
分子名称: Dihydroxyacetone, PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit dhaK
著者Jeckelmann, J.M, Zurbriggen, A, Christen, S, Baumann, U, Erni, B.
登録日2008-04-11
公開日2008-10-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.498 Å)
主引用文献X-ray Structures of the Three Lactococcus lactis Dihydroxyacetone Kinase Subunits and of a Transient Intersubunit Complex.
J.Biol.Chem., 283, 2008
3CWU
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Crystal Structure of an AlkA Host/Guest Complex 2'-fluoro-2'-deoxy-1,N6-ethenoadenine:Thymine Base Pair
分子名称: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(2FE)P*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DTP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2008-04-22
公開日2008-09-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
3CXQ
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Crystal structure of human glucosamine 6-phosphate N-acetyltransferase 1 bound to GlcN6P
分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, Glucosamine 6-phosphate N-acetyltransferase
著者Wang, J, Liu, X, Li, L.-F, Su, X.-D.
登録日2008-04-25
公開日2008-09-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1
Febs Lett., 582, 2008
3AL6
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Crystal structure of Human TYW5
分子名称: 2-OXOGLUTARIC ACID, JmjC domain-containing protein C2orf60, NICKEL (II) ION
著者Kato, M, Araiso, Y, Ishitani, R, Nureki, O.
登録日2010-07-26
公開日2010-12-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.
Nucleic Acids Res., 39, 2011
3A52
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Crystal structure of cold-active alkailne phosphatase from psychrophile Shewanella sp.
分子名称: Cold-active alkaline phosphatase, MAGNESIUM ION, SULFATE ION, ...
著者Tsuruta, H, Mikami, B, Higashi, T, Aizono, Y.
登録日2009-07-24
公開日2010-04-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of cold-active alkaline phosphatase from the psychrophile Shewanella sp.
Biosci.Biotechnol.Biochem., 74, 2010
3CWS
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Crystal Structure of an AlkA Host/Guest Complex 2'-fluoro-2'-deoxyinosine:Thymine Base Pair
分子名称: DNA (5'-D(*DGP*DAP*DCP*DAP*DTP*DGP*DAP*(2FI)P*DTP*DGP*DCP*DC)-3'), DNA (5'-D(*DGP*DGP*DCP*DAP*DTP*DTP*DCP*DAP*DTP*DGP*DTP*DC)-3'), DNA-3-methyladenine glycosylase 2
著者Bowman, B.R, Lee, S, Wang, S, Verdine, G.L.
登録日2008-04-22
公開日2008-09-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the E. coli DNA Glycosylase AlkA Bound to the Ends of Duplex DNA: A System for the Structure Determination of Lesion-Containing DNA.
Structure, 16, 2008
3D34
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Structure of the F-spondin domain of mindin
分子名称: CALCIUM ION, NICKEL (II) ION, Spondin-2
著者Li, Y, Mariuzza, R.A.
登録日2008-05-09
公開日2009-02-17
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the F-spondin domain of mindin, an integrin ligand and pattern recognition molecule.
Embo J., 28, 2009
3CZE
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Crystal Structure Analysis of Sucrose hydrolase (SUH)- Tris complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Sucrose hydrolase
著者Kim, M.I, Rhee, S.
登録日2008-04-29
公開日2008-07-15
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures and mutagenesis of sucrose hydrolase from Xanthomonas axonopodis pv. glycines: insight into the exclusively hydrolytic amylosucrase fold.
J.Mol.Biol., 380, 2008
3D63
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Crystal structure of inorganic pyrophosphatase from Burkholderia pseudomallei
分子名称: Inorganic pyrophosphatase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2008-05-18
公開日2008-07-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Combining functional and structural genomics to sample the essential Burkholderia structome.
Plos One, 8, 2013
3D1J
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Crystal Structure of E.coli GS mutant dmGS(C7S;C408S)
分子名称: Glycogen synthase
著者Sheng, F, Geiger, J.H.
登録日2008-05-06
公開日2009-03-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Crystal Structures of the Open and Catalytically Competent Closed Conformation of Escherichia coli Glycogen Synthase.
J.Biol.Chem., 284, 2009
3D6T
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Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
著者Deng, J.
登録日2008-05-20
公開日2008-06-10
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
Proc.Natl.Acad.Sci.Usa, 105, 2008
3CGZ
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Crystal Structure of Salmonella Sensor Kinase PhoQ catalytic domain
分子名称: Virulence sensor histidine kinase phoQ
著者Guarnieri, M.T, Zhang, L, Shen, J, Zhao, R.
登録日2008-03-06
公開日2008-05-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Hsp90 inhibitor radicicol interacts with the ATP-binding pocket of bacterial sensor kinase PhoQ.
J.Mol.Biol., 379, 2008

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