PDB: 83343 件ウェブページステータス検索Chemie searchBIRD

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5EVF	Crystal structure of a Francisella virulence factor FvfA in the hexagonal form 分子名称: CHLORIDE ION, Francisella virulence factor, GLYCEROL 著者 Kolappan, S, Lo, K.Y, Shen, C.L.J, Guttman, J.A, Craig, L. 登録日 2015-11-19 公開日 2016-10-26 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 Structure of the conserved Francisella virulence protein FvfA. Acta Crystallogr D Struct Biol, 73, 2017
1KIE	Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with 3-deaza-adenosine 分子名称: 3-DEAZA-ADENOSINE, CALCIUM ION, NICKEL (II) ION, ... 著者 Versees, W, Decanniere, K, Van Holsbeke, E, Devroede, N, Steyaert, J. 登録日 2001-12-03 公開日 2002-05-15 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. J.Biol.Chem., 277, 2002
4EFD	Crystal Structure of an M17 aminopeptidase from Trypanosoma Brucei, Tb427tmp.02.4440 分子名称: Aminopeptidase, GLYCEROL, MANGANESE (II) ION, ... 著者 Wernimont, A.K, Osman, K.T, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) 登録日 2012-03-29 公開日 2012-05-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal Structure of an M17 aminopeptidase from Trypanosoma Brucei, Tb427tmp.02.4440 To be Published
1KIC	Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with inosine 分子名称: CALCIUM ION, INOSINE, NICKEL (II) ION, ... 著者 Versees, W, Decanniere, K, Van Holsbeke, E, Devroede, N, Steyaert, J. 登録日 2001-12-03 公開日 2002-05-15 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. J.Biol.Chem., 277, 2002
5BSI	Crystal structure of Y36A mutant of human macrophage migration inhibitory factor 分子名称: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION 著者 Pantouris, G, Lolis, E. 登録日 2015-06-02 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
5FF5	Crystal Structure of SeMet PaaA 分子名称: GLYCEROL, NICKEL (II) ION, PaaA, ... 著者 Biernat, K.B, Redinbo, M.R. 登録日 2015-12-17 公開日 2016-04-27 最終更新日 2016-05-18 実験手法 X-RAY DIFFRACTION (2.933 Å) 主引用文献 Post-translational Claisen Condensation and Decarboxylation en Route to the Bicyclic Core of Pantocin A. J.Am.Chem.Soc., 138, 2016
1QLQ	Bovine Pancreatic Trypsin Inhibitor (BPTI) Mutant with Altered Binding Loop Sequence 分子名称: PANCREATIC TRYPSIN INHIBITOR, SULFATE ION 著者 Czapinska, H, Krzywda, S, Sheldrick, G.M, Otlewski, J, Jaskolski, M. 登録日 1999-09-10 公開日 1999-10-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 High Resolution Structure of Bovine Pancreatic Trypsin Inhibitor with Altered Binding Loop Sequence J.Mol.Biol., 295, 1999
1MXH	Crystal Structure of Substrate Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi 分子名称: DIHYDROFOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE 2 著者 Schormann, N, Pal, B, Senkovich, O, Carson, M, Howard, A, Smith, C, Delucas, L, Chattopadhyay, D. 登録日 2002-10-02 公開日 2003-10-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor. J.Struct.Biol., 152, 2005
6JIG	Crystal structure of GMP reductase C318A from Trypanosoma brucei in complex with guanosine 5'-monophosphate 分子名称: GMP reductase, GUANOSINE-5'-MONOPHOSPHATE, POTASSIUM ION 著者 Mase, H, Imamura, A, Nishimura, S, Inui, T. 登録日 2019-02-21 公開日 2020-02-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-beta-synthase domain. Nat Commun, 11, 2020
6JL8	Crystal structure of GMP reductase C318A from Trypanosoma brucei 分子名称: GMP reductase 著者 Mase, H, Imamura, A, Nishimura, S, Inui, T. 登録日 2019-03-04 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.804 Å) 主引用文献 Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-beta-synthase domain. Nat Commun, 11, 2020
3MCV	Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+ 分子名称: 5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]pyrimidine-2,4-diamine, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Tulloch, L.B, Hunter, W.N. 登録日 2010-03-29 公開日 2010-06-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 High-resolution structures of Trypanosoma brucei pteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug target. Acta Crystallogr.,Sect.D, 66, 2010
6LK4	Crystal structure of GMP reductase from Trypanosoma brucei in complex with guanosine 5'-triphosphate 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Guanosine 5'-monophosphate Reductase, PHOSPHATE ION 著者 Mase, H, Otani, T, Imamura, A, Nishimura, S, Inui, T. 登録日 2019-12-18 公開日 2020-03-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.503 Å) 主引用文献 Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-beta-synthase domain. Nat Commun, 11, 2020
5DVI	High resolution crystal Structure of glucose complexed periplasmic glucose binding protein (ppGBP) from P. putida CSV86 分子名称: Binding protein component of ABC sugar transporter, GLYCEROL, SULFATE ION, ... 著者 Pandey, S, Modak, A, Phale, P.S, Bhaumik, P. 登録日 2015-09-21 公開日 2016-02-24 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 High Resolution Structures of Periplasmic Glucose-binding Protein of Pseudomonas putida CSV86 Reveal Structural Basis of Its Substrate Specificity J.Biol.Chem., 291, 2016
1MXF	Crystal Structure of Inhibitor Complex of Putative Pteridine Reductase 2 (PTR2) from Trypanosoma cruzi 分子名称: METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PTERIDINE REDUCTASE 2 著者 Schormann, N, Pal, B, Senkovich, O, Carson, M, Howard, A, Smith, C, Delucas, L, Chattopadhyay, D. 登録日 2002-10-02 公開日 2003-10-14 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of Trypanosoma cruzi pteridine reductase 2 in complex with a substrate and an inhibitor. J.Struct.Biol., 152, 2005
5E7Y	Crystal structure of P450 BM3 heme domain M7 variant 分子名称: Bifunctional P-450/NADPH-P450 reductase, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE 著者 Panneerselvm, S, Shehzad, A, Bocola, M, Mueller-Dieckmann, J, Schwaneberg, U. 登録日 2015-10-13 公開日 2017-01-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of P450 BM3 heme domain M7 variant To Be Published
5DVJ	Crystal structure of galactose complexed periplasmic glucose binding protein (ppGBP) from P. putida CSV86 分子名称: Binding protein component of ABC sugar transporter, GLYCEROL, SULFATE ION, ... 著者 Pandey, S, Modak, A, Phale, P.S, Bhaumik, P. 登録日 2015-09-21 公開日 2016-02-17 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High Resolution Structures of Periplasmic Glucose-binding Protein of Pseudomonas putida CSV86 Reveal Structural Basis of Its Substrate Specificity J.Biol.Chem., 291, 2016
3M1P	Structure of ribose 5-phosphate isomerase type B from Trypanosoma cruzi, soaked with allose-6-phosphate 分子名称: PHOSPHATE ION, Ribose 5-phosphate isomerase 著者 Naworyta, A, Mowbray, S.L, Stern, A.L. 登録日 2010-03-05 公開日 2011-01-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family. Febs J., 278, 2011
4LZ5	Crystal structures of GLuR2 ligand-binding-domain in complex with glutamate and positive allosteric modulators 分子名称: GLUTAMIC ACID, Glutamate receptor 2, N-[(2R)-2-(4'-cyanobiphenyl-4-yl)propyl]propane-2-sulfonamide, ... 著者 Pandit, J. 登録日 2013-07-31 公開日 2013-12-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Discovery and Characterization of a Novel Dihydroisoxazole Class of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) Receptor Potentiators. J.Med.Chem., 56, 2013
1TSI	STRUCTURE OF THE COMPLEX BETWEEN TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AND N-HYDROXY-4-PHOSPHONO-BUTANAMIDE: BINDING AT THE ACTIVE SITE DESPITE AN "OPEN" FLEXIBLE LOOP 分子名称: N-HYDROXY-4-PHOSPHONO-BUTANAMIDE, TRIOSEPHOSPHATE ISOMERASE 著者 Verlinde, C.L.M.J. 登録日 1992-11-19 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Structure of the complex between trypanosomal triosephosphate isomerase and N-hydroxy-4-phosphono-butanamide: binding at the active site despite an "open" flexible loop conformation. Protein Sci., 1, 1992
1LJV	Bovine Pancreatic Polypeptide Bound to DPC Micelles 分子名称: PANCREATIC HORMONE 著者 Lerch, M, Gafner, V, Bader, R, Christen, B, Zerbe, O. 登録日 2002-04-22 公開日 2002-10-09 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Bovine pancreatic polypeptide (bPP) undergoes significant changes in conformation and dynamics upon binding to DPC micelles. J.Mol.Biol., 322, 2002
4MYF	Crystal structure of Trypanosoma cruzi formiminoglutamase(oxidized) with Mn2+2 at pH 6.0 分子名称: Formiminoglutamase, MANGANESE (II) ION 著者 Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. 登録日 2013-09-27 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013
6DIG	Crystal structure of DQA1*01:02/DQB1*06:02 in complex with a hypocretin peptide 分子名称: 13-mer peptide: ALA-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-LEU-GLY-LYS, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Birtley, J.R, Stern, L.J, Mellins, E.D, Jiang, W. 登録日 2018-05-23 公開日 2019-05-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 In vivo clonal expansion and phenotypes of hypocretin-specific CD4+T cells in narcolepsy patients and controls. Nat Commun, 10, 2019
4DE5	Pantothenate synthetase in complex with fragment 6 分子名称: (2S)-2,3-dihydro-1,4-benzodioxine-2-carboxylic acid, 1,2-ETHANEDIOL, ETHANOL, ... 著者 Silvestre, H.L. 登録日 2012-01-19 公開日 2013-03-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery. Proc.Natl.Acad.Sci.USA, 110, 2013
4BP8	Oligopeptidase B from Trypanosoma brucei - open form 分子名称: OLIGOPEPTIDASE B 著者 Canning, P, Rea, D, Morty, R, Fulop, V. 登録日 2013-05-23 公開日 2014-02-12 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structures of Trypanosoma Brucei Oligopeptidase B Broaden the Paradigm of Catalytic Regulation in Prolyl Oligopeptidase Family Enzymes. Plos One, 8, 2013
4MYL	Crystal structure of Trypanosoma cruzi Formiminoglutamase (oxidized) at pH 4.6 分子名称: Formiminoglutamase 著者 Hai, Y, Dugery, R.J, Healy, D, Christianson, D.W. 登録日 2013-09-27 公開日 2013-11-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.531 Å) 主引用文献 Formiminoglutamase from trypanosoma cruzi is an arginase-like manganese metalloenzyme. Biochemistry, 52, 2013

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