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3AS1
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Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with chelerythrine
分子名称: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Chitinase A, GLYCEROL
著者Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W.
登録日2010-12-09
公開日2011-04-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms
J.Biol.Chem., 286, 2011
2IDC
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BU of 2idc by Molmil
Structure of the Histone H3-Asf1 Chaperone Interaction
分子名称: ANTI-SILENCING PROTEIN 1 AND HISTONE H3 CHIMERA
著者Antczak, A.J, Tsubota, T, Kaufman, P.D, Berger, J.M.
登録日2006-09-14
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the yeast histone H3-ASF1 interaction: implications for chaperone mechanism, species-specific interactions, and epigenetics.
Bmc Struct.Biol., 6, 2006
2IT0
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BU of 2it0 by Molmil
Crystal structure of a two-domain IdeR-DNA complex crystal form II
分子名称: ACETATE ION, Iron-dependent repressor ideR, NICKEL (II) ION, ...
著者Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G.
登録日2006-10-18
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis
Biochemistry, 46, 2007
3AV5
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BU of 3av5 by Molmil
Crystal structure of mouse DNA methyltransferase 1 with AdoHcy
分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
著者Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S.
登録日2011-02-22
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).
Proc.Natl.Acad.Sci.USA, 108, 2011
2IF0
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BU of 2if0 by Molmil
Crystal Structure of mouse Rab27b bound to GDP in monoclinic space group
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-27B
著者Chavas, L.M.G, Torii, S, Kamikubo, H, Kawasaki, M, Ihara, K, Kato, R, Kataoka, M, Izumi, T, Wakatsuki, S.
登録日2006-09-19
公開日2007-05-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
2IMW
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BU of 2imw by Molmil
Mechanism of Template-Independent Nucleotide Incorporation Catalyzed by a Template-Dependent DNA Polymerase
分子名称: 1,2-ETHANEDIOL, 2',3'-dideoxyadenosine triphosphate, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3', ...
著者Ling, H, Yang, W.
登録日2006-10-05
公開日2007-01-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mechanism of Template-independent Nucleotide Incorporation Catalyzed by a Template-dependent DNA Polymerase.
J.Mol.Biol., 365, 2007
3AV6
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Crystal structure of mouse DNA methyltransferase 1 with AdoMet
分子名称: DNA (cytosine-5)-methyltransferase 1, S-ADENOSYLMETHIONINE, ZINC ION
著者Takeshita, K, Suetake, I, Yamashita, E, Suga, M, Narita, H, Nakagawa, A, Tajima, S.
登録日2011-02-22
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).
Proc.Natl.Acad.Sci.USA, 108, 2011
3AYH
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BU of 3ayh by Molmil
Crystal structure of the C17/25 subcomplex from S. pombe RNA Polymerase III
分子名称: DNA-directed RNA polymerase III subunit rpc8, DNA-directed RNA polymerase III subunit rpc9, SULFATE ION
著者Ehara, H, Sekine, S, Yokoyama, S.
登録日2011-05-06
公開日2011-07-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.193 Å)
主引用文献Crystal structure of the C17/25 subcomplex from Schizosaccharomyces pombe RNA polymerase III
Protein Sci., 20, 2011
2IQ1
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Crystal structure of human PPM1K
分子名称: MAGNESIUM ION, Protein phosphatase 2C kappa, PPM1K
著者Bonanno, J.B, Freeman, J, Russell, M, Bain, K.T, Adams, J, Pelletier, L, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2006-10-12
公開日2006-11-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural genomics of protein phosphatases
J.STRUCT.FUNCT.GENOM., 8, 2007
2IC6
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BU of 2ic6 by Molmil
The Coiled-coil Domain (residues 1-75) Structure of the Sin Nombre Virus Nucleocapsid Protein
分子名称: Nucleocapsid protein
著者Boudko, S.P, Rossmann, M.G.
登録日2006-09-12
公開日2007-02-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献The Coiled-coil Domain Structure of the Sin Nombre Virus Nucleocapsid Protein.
J.Mol.Biol., 366, 2007
3ARW
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BU of 3arw by Molmil
Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with chelerythrine
分子名称: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Chitinase A, GLYCEROL
著者Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W.
登録日2010-12-09
公開日2011-04-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms
J.Biol.Chem., 286, 2011
3ASG
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BU of 3asg by Molmil
MamA D159K mutant 2
分子名称: MamA
著者Zeytuni, N, Levin, M, Davidov, G, Zarivach, R.
登録日2010-12-11
公開日2011-07-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Self-recognition mechanism of MamA, a magnetosome-associated TPR-containing protein, promotes complex assembly
Proc.Natl.Acad.Sci.USA, 108, 2011
3AWR
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Crystal structure of Rat TOM20-ALDH presequence complex: The intermolecular disulfide bond was cleaved in the crystal of a disulfide-tethered complex.
分子名称: Aldehyde dehydrogenase, mitochondrial, Mitochondrial import receptor subunit TOM20 homolog
著者Igura, M, Ose, T, Kohda, D.
登録日2011-03-26
公開日2011-07-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic snapshots of tom20-mitochondrial presequence interactions with disulfide-stabilized peptides.
Biochemistry, 50, 2011
3B0L
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BU of 3b0l by Molmil
M175G mutant of assimilatory nitrite reductase (Nii3) from tobbaco leaf
分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, Nitrite reductase, ...
著者Nakano, S, Takahashi, M, Sakamoto, A, Morikawa, H, Katayanagi, K.
登録日2011-06-10
公開日2012-02-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure-function relationship of assimilatory nitrite reductases from the leaf and root of tobacco based on high resolution structures
Protein Sci., 21, 2012
4QA9
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BU of 4qa9 by Molmil
Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus.
分子名称: 1,2-ETHANEDIOL, Epoxide hydrolase, SULFATE ION
著者Wang, F, Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Joachimiak, A, Phillips Jr, G.N, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-05-02
公開日2014-05-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Ensemble refinement of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus.
To be Published
4Q9T
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BU of 4q9t by Molmil
Crystal structure of Vanderwaltozyma polyspora Nup133 Beta-propeller domain
分子名称: Nucleoporin NUP133
著者Sampathkumar, P, Bonanno, J.B, Almo, S.C, Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals), New York SGX Research Center for Structural Genomics (NYSGXRC), New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-05-01
公開日2014-06-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of Vanderwaltozyma polyspora Nup133 Beta-propeller domain
to be published
3BCE
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BU of 3bce by Molmil
Crystal structure of the ErbB4 kinase
分子名称: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, Receptor tyrosine-protein kinase erbB-4, ...
著者Qiu, C.
登録日2007-11-12
公開日2008-02-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
3BCZ
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BU of 3bcz by Molmil
Crystal structure of Memo
分子名称: GLYCEROL, Protein MEMO1
著者Qiu, C.
登録日2007-11-13
公開日2007-11-27
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Memo Is Homologous to Nonheme Iron Dioxygenases and Binds an ErbB2-derived Phosphopeptide in Its Vestigial Active Site.
J.Biol.Chem., 283, 2008
3BFK
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BU of 3bfk by Molmil
Crystal structure of Plasmodium falciparum Rab11a in complex with GDP
分子名称: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, Small GTPase Rab11
著者Pizarro, J.C, Sukumar, D, Hassanali, A, Lin, L, Wernimont, A.K, Lew, J, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
登録日2007-11-21
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of Plasmodium falciparum Rab11a in complex with GDP.
To be Published
3BGP
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BU of 3bgp by Molmil
Human Pim-1 complexed with a benzoisoxazole inhibitor VX1
分子名称: 4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Jacobs, M.D.
登録日2007-11-27
公開日2007-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Docking study yields four novel inhibitors of the protooncogene pim-1 kinase.
J.Med.Chem., 51, 2008
2ING
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BU of 2ing by Molmil
X-ray Structure of the BRCA1 BRCT mutant M1775K
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
著者Birrane, G, Soni, A, Ladias, J.A.A.
登録日2006-10-07
公開日2007-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Eur.J.Hum.Genet., 16, 2008
2IO1
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Crystal structure of human Senp2 in complex with preSUMO-3
分子名称: Sentrin-specific protease 2, Small ubiquitin-related modifier 3 precursor
著者Reverter, D, Lima, C.D.
登録日2006-10-09
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates.
Nat.Struct.Mol.Biol., 13, 2006
2IPH
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X-ray Structure at 1.75 A Resolution of a Norovirus Protease Linked to an Active Site Directed Peptide Inhibitor
分子名称: N-ACETYL-L-ALPHA-GLUTAMYL-L-PHENYLALANYL-L-GLUTAMINYL-N-[(1S)-4-AMINO-1-(2-CARBOXYETHYL)-4-OXOBUTYL]-L-LEUCINAMIDE, Thiol protease P3C
著者Hussey, R.J.
登録日2006-10-12
公開日2007-10-23
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide Inhibitor.
Biochemistry, 50, 2011
3B0M
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M175K mutant of assimilatory nitrite reductase (Nii3) from tobbaco leaf
分子名称: CHLORIDE ION, IRON/SULFUR CLUSTER, Nitrite reductase, ...
著者Nakano, S, Takahashi, M, Sakamoto, A, Morikawa, H, Katayanagi, K.
登録日2011-06-10
公開日2012-02-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-function relationship of assimilatory nitrite reductases from the leaf and root of tobacco based on high resolution structures
Protein Sci., 21, 2012
4QKX
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Structure of beta2 adrenoceptor bound to a covalent agonist and an engineered nanobody
分子名称: 4-[(1R)-1-hydroxy-2-({2-[3-methoxy-4-(2-sulfanylethoxy)phenyl]ethyl}amino)ethyl]benzene-1,2-diol, Beta-2 adrenergic receptor, R9 protein, ...
著者Weichert, D, Kruse, A.C, Manglik, A, Hiller, C, Zhang, C, Huebner, H, Kobilka, B.K, Gmeiner, P.
登録日2014-06-10
公開日2014-07-23
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Covalent agonists for studying G protein-coupled receptor activation.
Proc.Natl.Acad.Sci.USA, 111, 2014

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