PDB: 5558 件ウェブページステータス検索Chemie searchBIRD

---

5GTC	Crystal structure of complex between DMAP-SH conjugated with a Kaposi's sarcoma herpesvirus LANA peptide (5-15) and nucleosome core particle 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... 著者 Arimura, Y, Kato, D, Suto, H, Kurumizaka, H, Kawashima, S.A, Yamatsugu, K, Kanai, M. 登録日 2016-08-19 公開日 2017-06-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Synthetic Posttranslational Modifications: Chemical Catalyst-Driven Regioselective Histone Acylation of Native Chromatin. J. Am. Chem. Soc., 139, 2017
6L49	H3-CA-H3 tri-nucleosome with the 22 base-pair linker DNA 分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H. 登録日 2019-10-16 公開日 2019-12-04 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (18.9 Å) 主引用文献 Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome. Structure, 28, 2020
6KXV	Crystal structure of a nucleosome containing Leishmania histone H3 分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Dacher, M, Taguchi, H, Kujirai, T, Kurumizaka, H. 登録日 2019-09-13 公開日 2020-07-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.63 Å) 主引用文献 Incorporation and influence of Leishmania histone H3 in chromatin. Nucleic Acids Res., 47, 2019
6LA8	349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 分子名称: CALCIUM ION, DNA (349-MER), Histone H1.0, ... 著者 Adhireksan, Z, Lee, P.L, Sharma, D, Davey, C.A. 登録日 2019-11-12 公開日 2020-10-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Near-atomic resolution structures of interdigitated nucleosome fibres. Nat Commun, 11, 2020
6KVD	Crystal structure of human nucleosome containing H2A.J 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A.J, ... 著者 Tanaka, H, Koyama, M, Sato, S, Kujirai, T, Kurumizaka, H. 登録日 2019-09-04 公開日 2019-12-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Biochemical and structural analyses of the nucleosome containing human histone H2A.J. J.Biochem., 167, 2020
6L4A	H3-H3-H3 tri-nucleosome with the 22 base-pair linker DNA 分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H. 登録日 2019-10-16 公開日 2019-12-04 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (12.3 Å) 主引用文献 Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome. Structure, 28, 2020
5GWJ	Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873S 分子名称: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ... 著者 Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L. 登録日 2016-09-12 公開日 2017-08-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.566 Å) 主引用文献 Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry Nucleic Acids Res., 45, 2017
6LA9	349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 (high cryoprotectant) 分子名称: CALCIUM ION, DNA (349-MER), Histone H1.0, ... 著者 Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. 登録日 2019-11-12 公開日 2020-10-07 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Near-atomic resolution structures of interdigitated nucleosome fibres. Nat Commun, 11, 2020
6IEH	Crystal structures of the hMTR4-NRDE2 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... 著者 Chen, J.Y, Yun, C.H. 登録日 2018-09-14 公開日 2019-04-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.892 Å) 主引用文献 NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction. Genes Dev., 33, 2019
6J4X	RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome (+1A) 分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... 著者 Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2019-01-10 公開日 2019-02-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
6JFB	Crystal structure of human pyruvate kinase M2 isoform 分子名称: PHOSPHATE ION, Pyruvate kinase PKM Isoform M2, SERINE 著者 Chen, T.J, Wang, W.C. 登録日 2019-02-08 公開日 2020-04-01 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Crystal structure of human pyruvate kinase M2 isoform To Be Published
6J4Z	RNA polymerase II elongation complex bound with Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome 分子名称: DNA (198-MER), DNA (42-MER), DNA-directed RNA polymerase subunit, ... 著者 Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S. 登録日 2019-01-10 公開日 2019-02-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insight into nucleosome transcription by RNA polymerase II with elongation factors. Science, 363, 2019
6JR1	Crystal structure of the human nucleosome phased with 16 selenium atoms 分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... 著者 Saotome, M, Horikoshi, N, Urano, K, Kujirai, T, Yuzurihara, H, Kurumizaka, H, Kagawa, W. 登録日 2019-04-02 公開日 2019-10-02 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure determination of the nucleosome core particle by selenium SAD phasing. Acta Crystallogr D Struct Biol, 75, 2019
5H1V	Complex structure of TRIM24 PHD-bromodomain and inhibitor 6 分子名称: 2-Hydrazino-1,3-benzothiazole-6-carbohydrazide, DIMETHYL SULFOXIDE, Transcription intermediary factor 1-alpha, ... 著者 Liu, J. 登録日 2016-10-11 公開日 2017-02-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.002 Å) 主引用文献 The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network FEBS J., 284, 2017
6M4G	Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2 分子名称: DNA (93-MER), Histone H2A-Bbd type 2/3, Histone H2B type 2-E, ... 著者 Zhou, M, Dai, L.C, Li, C.M, Shi, L.X, Huang, Y, Guo, Z.Q. 登録日 2020-03-06 公開日 2020-09-23 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2. Embo J., 40, 2021
5FXY	Structure of the human RBBP4:MTA1(464-546) complex 分子名称: HISTONE-BINDING PROTEIN RBBP4, METASTASIS-ASSOCIATED PROTEIN MTA1 著者 Millard, C.J, Varma, N, Fairall, L, Schwabe, J.W.R. 登録日 2016-03-03 公開日 2016-05-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The structure of the core NuRD repression complex provides insights into its interaction with chromatin. Elife, 5, 2016
6M4H	Structural mechanism of nucleosome dynamics governed by human histone variants H2A.B and H2A.Z.2.2 分子名称: DNA (103-MER), Histone H2A-Bbd type 2/3, Histone H2B type 2-E, ... 著者 Zhou, M, Dai, L.C, Li, C.M, Shi, L.X, Huang, Y, Guo, Z.Q. 登録日 2020-03-07 公開日 2020-09-23 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis of nucleosome dynamics modulation by histone variants H2A.B and H2A.Z.2.2. Embo J., 40, 2021
6K1K	Human nucleosome core particle with H2A.X S139E variant 分子名称: CHLORIDE ION, DNA (145-MER), Histone H2AX, ... 著者 Sharma, D, De Falco, L, Davey, C.A. 登録日 2019-05-10 公開日 2020-01-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome. Nat Commun, 10, 2019
6M44	355 bp di-nucleosome harboring cohesive DNA termini (high cryoprotectant) 分子名称: CALCIUM ION, DNA (355-MER), Histone H2A type 1-B/E, ... 著者 Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. 登録日 2020-03-05 公開日 2020-10-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.81 Å) 主引用文献 Near-atomic resolution structures of interdigitated nucleosome fibres. Nat Commun, 11, 2020
6M3V	355 bp di-nucleosome harboring cohesive DNA termini 分子名称: CALCIUM ION, DNA (355-MER), Histone H2A type 1-B/E, ... 著者 Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. 登録日 2020-03-04 公開日 2020-10-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (4.6 Å) 主引用文献 Near-atomic resolution structures of interdigitated nucleosome fibres. Nat Commun, 11, 2020
5FLX	Mammalian 40S HCV-IRES complex 分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... 著者 Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T. 登録日 2015-10-28 公開日 2015-12-23 最終更新日 2017-08-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA. Embo J., 34, 2015
5FA5	Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide 分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Histone H4, Methylosome protein 50, ... 著者 Sprague, E.R, McNamara, J.T. 登録日 2015-12-10 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5. Science, 351, 2016
6L9Z	338 bp di-nucleosome assembled with linker histone H1.X 分子名称: CALCIUM ION, CHLORIDE ION, DNA (338-MER), ... 著者 Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. 登録日 2019-11-11 公開日 2021-02-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021
6LAB	169 bp nucleosome, harboring cohesive DNA termini, assembled with linker histone H1.0 分子名称: CALCIUM ION, CHLORIDE ION, DNA (169-MER), ... 著者 Adhireksan, Z, Sharma, D, Bao, Q, Lee, P.L, Padavattan, S, Davey, C.A. 登録日 2019-11-12 公開日 2021-02-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021
6LA2	343 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 分子名称: DNA (343-MER), Histone H1.0, Histone H2A type 1-B/E, ... 著者 Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. 登録日 2019-11-11 公開日 2021-02-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.89 Å) 主引用文献 Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021

<47484950515253545556575859606162>