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5AKV
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Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: genistein-7-O- glucuronide
分子名称: Genistein-7-O-glucuronide, TRANSTHYRETIN
著者Florio, P, Foll, C, Cianci, M, Del Rio, D, Zanotti, G, Berni, R.
登録日2015-03-05
公開日2015-10-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Transthyretin Binding Heterogeneity and Anti-Amyloidogenic Activity of Natural Polyphenols and Their Metabolites
J.Biol.Chem., 290, 2015
6ZUS
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Crystal structure of the effector Ecp11-1 from Fulvia fulva
分子名称: DI(HYDROXYETHYL)ETHER, Extracellular protein 11-1, GLYCEROL, ...
著者Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I.
登録日2020-07-23
公開日2021-08-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
6ZUQ
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Crystal structure of the effector Ecp11-1 from Fulvia fulva
分子名称: Extracellular protein 11-1, GLYCEROL, ZINC ION
著者Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I.
登録日2020-07-23
公開日2021-08-04
最終更新日2022-07-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
7AD5
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Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans
分子名称: ACETATE ION, Avirulence protein LmJ1, GLYCEROL, ...
著者Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I.
登録日2020-09-14
公開日2021-10-06
最終更新日2022-07-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins.
Plos Pathog., 18, 2022
3DJS
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Crystal structure of transthyretin variant L58H at acidic pH
分子名称: Transthyretin
著者Cendron, L, Zanotti, G, Folli, C, Berni, R.
登録日2008-06-24
公開日2009-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Amyloidogenic potential of transthyretin variants: insights from structural and computational analyses.
J.Biol.Chem., 284, 2009
3DJZ
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BU of 3djz by Molmil
Crystal structure of transthyretin variant L55P at neutral pH
分子名称: Transthyretin
著者Cendron, L, Zanotti, G, Folli, C, Berni, R.
登録日2008-06-24
公開日2009-07-14
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Amyloidogenic potential of transthyretin variants: insights from structural and computational analyses.
J.Biol.Chem., 284, 2009
4P5K
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BU of 4p5k by Molmil
Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity
分子名称: HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, ...
著者Clayton, G.M, Wang, Y, Crawford, F, Novikov, A, Wimberly, B.T, Kieft, J.S, Falta, M.T, Bowerman, N.A, Marrack, P, Fontenot, A.P, Dai, S, Kappler, J.W.
登録日2014-03-17
公開日2015-01-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
7SZZ
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Structure of the smaller diameter PSMalpha3 nanotubes
分子名称: Phenol-soluble modulin PSM-alpha-3
著者Beltran, L.C, Kreutzberger, M.A, Wang, S, Egelman, E.H, Conticello, V.P.
登録日2021-11-29
公開日2022-05-18
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T8U
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Structure of PSMbeta2 nanotubes
分子名称: Antibacterial protein
著者Kreutzberger, M.A, Wang, S, Egelman, E.H, Conicello, V.P.
登録日2021-12-17
公開日2022-05-18
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T0X
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Structure of the larger diameter PSMalpha3 nanotube
分子名称: Phenol-soluble modulin PSM-alpha-3
著者Kreutzberger, M.A, Wang, S, Beltran, L.C, Egelman, E.H, Conticello, V.P.
登録日2021-11-30
公開日2022-05-18
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids.
Proc.Natl.Acad.Sci.USA, 119, 2022
6PX7
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BU of 6px7 by Molmil
Dg12a in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
分子名称: Venom polypeptide
著者Agwa, A.J, Schroeder, C.
登録日2019-07-25
公開日2020-01-22
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
2RGK
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BU of 2rgk by Molmil
Functional annotation of Escherichia coli yihS-encoded protein
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Uncharacterized sugar isomerase yihS
著者Itoh, T, Mikami, B, Hashimoto, W, Murata, K.
登録日2007-10-03
公開日2008-08-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of YihS in complex with D-mannose: structural annotation of Escherichia coli and Salmonella enterica yihS-encoded proteins to an aldose-ketose isomerase
J.Mol.Biol., 377, 2008
6PX8
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Dg3b in Weaponisation 'on the fly': Convergent recruitment of knottin and defensin scaffolds as neurotoxins in the venom of assassin fly Dolopus genitalis (Diptera: Asilidae)
分子名称: Venom polypeptide
著者Agwa, A.J, Schroeder, C.
登録日2019-07-25
公開日2020-01-22
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Weaponisation 'on the fly': Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies.
Insect Biochem.Mol.Biol., 118, 2019
4B9B
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BU of 4b9b by Molmil
The structure of the omega aminotransferase from Pseudomonas aeruginosa
分子名称: BETA-ALANINE-PYRUVATE TRANSAMINASE, CALCIUM ION, CHLORIDE ION, ...
著者Sayer, C, Isupov, M.N, Westlake, A, Littlechild, J.A.
登録日2012-09-03
公開日2013-03-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
5VEH
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BU of 5veh by Molmil
Re-refinement OF THE PDB STRUCTURE 1yiz of Aedes aegypti kynurenine aminotransferase
分子名称: BROMIDE ION, GLYCEROL, Kynurenine aminotransferase
著者Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B.
登録日2017-04-04
公開日2017-11-29
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018
6DQP
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Crystal structure of SsuE FMN reductase Delta118 mutant in apo form
分子名称: FMN reductase (NADPH), GLYCEROL
著者McFarlane, J.S, Ellis, H.R, Lamb, A.L.
登録日2018-06-11
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.546 Å)
主引用文献Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases.
Protein Sci., 28, 2019
6DQI
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BU of 6dqi by Molmil
Crystal structure of SsuE FMN reductase Y118A mutant in apo form.
分子名称: FMN reductase (NADPH), SULFATE ION
著者McFarlane, J.S, Ellis, H.R, Lamb, A.L.
登録日2018-06-11
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases.
Protein Sci., 28, 2019
6DQO
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Crystal structure of SsuE FMN reductase Y118A mutant in FMN bound form.
分子名称: FLAVIN MONONUCLEOTIDE, FMN reductase (NADPH), GLYCEROL
著者McFarlane, J.S, Ellis, H.R, Lamb, A.L.
登録日2018-06-11
公開日2019-01-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.705 Å)
主引用文献Not as easy as pi : An insertional residue does not explain the pi-helix gain-of-function in two-component FMN reductases.
Protein Sci., 28, 2019
4BA5
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BU of 4ba5 by Molmil
Crystal structure of omega-transaminase from Chromobacterium violaceum
分子名称: 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, AMINOTRANSFERASE, SULFATE ION
著者Sayer, C, Isupov, M.N, Littlechild, J.A.
登録日2012-09-11
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
4B98
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The structure of the omega aminotransferase from Pseudomonas aeruginosa
分子名称: 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, BETA-ALANINE--PYRUVATE TRANSAMINASE, CALCIUM ION, ...
著者Sayer, C, Isupov, M.N, Westlake, A, Littlechild, J.A.
登録日2012-09-03
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
8AZ8
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SARS-CoV-2 non-structural protein-1 (nsp1) in complex with 2-(benzylamino)ethan-1-ol
分子名称: 2-[(phenylmethyl)amino]ethanol, Host translation inhibitor nsp1
著者Ma, S, Damfo, S, Pinotsis, N, Bowler, M.W, Kozielski, F.
登録日2022-09-05
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening.
Int J Mol Sci, 23, 2022
4AO4
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BU of 4ao4 by Molmil
Structural Determinants of the beta-Selectivity of a Bacterial Aminotransferase
分子名称: (3R)-3-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]-5-METHYLHEXANOIC ACID, 1,2-ETHANEDIOL, Beta-transaminase
著者Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W.
登録日2012-03-23
公開日2012-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural determinants of the beta-selectivity of a bacterial aminotransferase.
J. Biol. Chem., 287, 2012
8ORS
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BU of 8ors by Molmil
Knockout of GMC-oxidoreductase genes reveals that functional redundancy preserves mimivirus essential functions
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase
著者Alempic, J.M, Bisio, H, Villalta, A, Santini, S, Lartigue, A, Schmitt, A, Bugnot, C, Notaro, A, Belmudes, L, Adrait, A, Poirot, O, Ptchelkine, D, De Castro, C, Coute, Y, Abergel, C.
登録日2023-04-17
公開日2024-04-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes.
Microlife, 5, 2024
8ORH
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BU of 8orh by Molmil
Knockout of GMC-oxidoreductase genes reveals that functional redundancy preserves mimivirus essential functions
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Putative GMC-type oxidoreductase
著者Alempic, J.M, Bisio, H, Villalta, A, Santini, S, Lartigue, A, Schmitt, A, Bugnot, C, Notaro, A, Belmudes, L, Adrait, A, Poirot, O, Ptchelkine, D, De Castro, C, Coute, Y, Abergel, C.
登録日2023-04-14
公開日2024-04-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes.
Microlife, 5, 2024
4C6Y
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Ancestral PNCA (last common ancestors of Gram-positive and Gram- negative bacteria) beta-lactamase class A
分子名称: ACETATE ION, BETA-LACTAMASE, CHLORIDE ION, ...
著者Gavira, J.A, Risso, V.A, Sanchez-Ruiz, J.M.
登録日2013-09-19
公開日2014-04-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Phenotypic Comparisons of Consensus Variants Versus Laboratory Resurrections of Precambrian Proteins.
Proteins, 82, 2014

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