5F92
 
 | | Fumarate hydratase of Mycobacterium tuberculosis in complex with formate | | 分子名称: | CHLORIDE ION, FORMIC ACID, Fumarate hydratase class II, ... | | 著者 | Kasbekar, M, Fischer, G, Mott, B.T, Yasgar, A, Hyvonen, M, Boshoff, H.I, Abell, C, Barry, C.E, Thomas, C.J. | | 登録日 | 2015-12-09 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.859 Å) | | 主引用文献 | Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2BZR
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1YBU
 | | Mycobacterium tuberculosis adenylyl cyclase Rv1900c CHD, in complex with a substrate analog. | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION, lipJ | | 著者 | Sinha, S.C, Wetterer, M, Sprang, S.R, Schultz, J.E, Linder, J.U. | | 登録日 | 2004-12-21 | | 公開日 | 2005-02-15 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c.
Embo J., 24, 2005
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1Y6X
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4ACF
 | | CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS GLUTAMINE SYNTHETASE IN COMPLEX WITH IMIDAZOPYRIDINE INHIBITOR ((4-(6-BROMO-3-(BUTYLAMINO)IMIDAZO(1,2-A)PYRIDIN-2-YL)PHENOXY) ACETIC ACID) AND L-METHIONINE-S-SULFOXIMINE PHOSPHATE. | | 分子名称: | CHLORIDE ION, GLUTAMINE SYNTHETASE 1, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ... | | 著者 | Nilsson, M.T, Mowbray, S.L. | | 登録日 | 2011-12-15 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synthesis, Biological Evaluation and X-Ray Crystallographic Studies of Imidazo(1,2-A)Pyridine-Based Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors
Medchemcomm, 3, 2012
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3OBA
 | | Structure of the beta-galactosidase from Kluyveromyces lactis | | 分子名称: | Beta-galactosidase, GLYCEROL, MANGANESE (III) ION | | 著者 | Fernandez-Leiro, R, Pereira-Rodriguez, A, Becerra, M, Gonzalez-Siso, I, Cerdan, M.E, Sanz-Aparicio, J. | | 登録日 | 2010-08-06 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural basis of specificity in tetrameric Kluyveromyces lactis beta-galactosidase.
J.Struct.Biol., 177, 2012
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2CBY
 | | Crystal structure of the ATP-dependent Clp Protease proteolytic subunit 1 (ClpP1) from Mycobacterium tuberculosis | | 分子名称: | ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 | | 著者 | Mate, M.J, Portnoi, D, Alzari, P.M, Ortiz-Lombardia, M. | | 登録日 | 2006-01-10 | | 公開日 | 2006-01-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1.
Acta Crystallogr.,Sect.D, 63, 2007
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2CDN
 | | Crystal structure of Mycobacterium tuberculosis adenylate kinase complexed with two molecules of ADP and Mg | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINASE, MAGNESIUM ION | | 著者 | Bellinzoni, M, Haouz, A, Grana, M, Munier-Lehmann, H, Alzari, P.M. | | 登録日 | 2006-01-25 | | 公開日 | 2006-05-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Crystal Structure of Mycobacterium Tuberculosis Adenylate Kinase in Complex with Two Molecules of Adp and Mg2+ Supports an Associative Mechanism for Phosphoryl Transfer.
Protein Sci., 15, 2006
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3DWI
 | | Crystal structure of Mycobacterium tuberculosis CysM, the cysteine synthase B | | 分子名称: | Cysteine synthase B, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | 著者 | Jurgenson, C.T, Burns, K.E, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-07-22 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis.
Biochemistry, 47, 2008
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4NEC
 | | Conversion of a Disulfide Bond into a Thioacetal Group during Echinomycin Biosynthesis | | 分子名称: | 2-CARBOXYQUINOXALINE, ACETATE ION, Echinomycin, ... | | 著者 | Hotta, K, Keegan, R.M, Ranganathan, S, Fang, M, Bibby, J, Winn, M.D, Sato, M, Lian, M, Watanabe, K, Rigden, D.J, Kim, C.-Y. | | 登録日 | 2013-10-29 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Conversion of a disulfide bond into a thioacetal group during echinomycin biosynthesis.
Angew.Chem.Int.Ed.Engl., 53, 2014
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3HGB
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3HYS
 | | Structure of Rv0554 from Mycobacterium tuberculosis complexed with Malonic Acid | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MALONIC ACID, ... | | 著者 | Johnston, J.M, Baker, E.N. | | 登録日 | 2009-06-23 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis.
Acta Crystallogr.,Sect.D, 66, 2010
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3ZXO
 | | CRYSTAL STRUCTURE OF THE MUTANT ATP-BINDING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | | 分子名称: | ACETATE ION, GLYCEROL, REDOX SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS, ... | | 著者 | Cho, H.Y, Cho, H.J, Kang, B.S. | | 登録日 | 2011-08-13 | | 公開日 | 2011-08-24 | | 最終更新日 | 2013-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Activation of ATP Binding for the Autophosphorylation of Doss, a Mycobacterium Tuberculosis Histidine Kinase Lacking an ATP-Lid Motif.
J.Biol.Chem., 288, 2013
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4MQM
 | | Crystal structure of Antigen 85C in presence of Ebselen | | 分子名称: | Diacylglycerol acyltransferase/mycolyltransferase Ag85C | | 著者 | Favrot, L, Grzegorzewicz, A.E, Lajiness, D.H, Marvin, R.K, Boucau, J, Isailovic, D, Jackson, M, Ronning, D.R. | | 登録日 | 2013-09-16 | | 公開日 | 2013-11-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.346 Å) | | 主引用文献 | Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen.
Nat Commun, 4, 2013
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2GQ2
 | | Mycobacterium tuberculosis ThyX-NADP complex | | 分子名称: | GLYCEROL, IODIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Sampathkumar, P, Turley, S, Sibley, C.H, Hol, W.G. | | 登録日 | 2006-04-19 | | 公開日 | 2006-06-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design.
J.Mol.Biol., 360, 2006
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3DWM
 | | Crystal structure of Mycobacterium tuberculosis CysO, an antigen | | 分子名称: | 9.5 kDa culture filtrate antigen cfp10A | | 著者 | Jurgenson, C.T, Burns, K.E, Begley, T.P, Ealick, S.E. | | 登録日 | 2008-07-22 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis.
Biochemistry, 47, 2008
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2QKX
 | | N-acetyl glucosamine 1-phosphate uridyltransferase from Mycobacterium tuberculosis complex with N-acetyl glucosamine 1-phosphate | | 分子名称: | 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, Bifunctional protein glmU | | 著者 | Zhang, Z, Squire, C.J, Baker, E.N, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2007-07-11 | | 公開日 | 2008-07-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure and function of GlmU from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 65, 2009
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2ASB
 | | Structure of a Mycobacterium tuberculosis NusA-RNA complex | | 分子名称: | Transcription elongation protein nusA, ribosomal RNA (5'- GAACUCAAUAG -3') | | 著者 | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | | 登録日 | 2005-08-23 | | 公開日 | 2005-10-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a Mycobacterium tuberculosis NusA-RNA complex.
Embo J., 24, 2005
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1YBT
 | | MYCOBACTERIUM TUBERCULOSIS ADENYLYL CYCLASE, RV1900C CHD | | 分子名称: | hydrolase, alpha/beta hydrolase fold family | | 著者 | Sinha, S.C, Wetterer, M, Sprang, S.R, Schultz, J.E, Linder, J.U. | | 登録日 | 2004-12-21 | | 公開日 | 2005-02-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c.
Embo J., 24, 2005
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7ZWJ
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3OB8
 | | Structure of the beta-galactosidase from Kluyveromyces lactis in complex with galactose | | 分子名称: | Beta-galactosidase, MAGNESIUM ION, MANGANESE (II) ION, ... | | 著者 | Fernandez-Leiro, R, Pereira-Rodriguez, A, Becerra, M, Gonzalez-Siso, I, Cerdan, M.E, Sanz-Aparicio, J. | | 登録日 | 2010-08-06 | | 公開日 | 2011-08-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis of specificity in tetrameric Kluyveromyces lactis beta-galactosidase.
J.Struct.Biol., 177, 2012
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3GYR
 | | Structure of Phenoxazinone synthase from Streptomyces antibioticus reveals a new type 2 copper center. | | 分子名称: | COPPER (II) ION, CU-O-CU LINKAGE, GLYCEROL, ... | | 著者 | Smith, A.W, Camara-Artigas, A, Wang, M, Francisco, W.A, Allen, J.P. | | 登録日 | 2009-04-05 | | 公開日 | 2009-04-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of Phenoxazinone Synthase from Streptomyces Antibioticus Reveals a New Type 2 Copper Center.
Biochemistry, 45, 2006
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3H5H
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3H5E
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4OQF
 | | Mycobacterium tuberculosis RecA glycerol bound low temperature structure IIB-SR | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein RecA | | 著者 | Chandran, A.V, Prabu, J.R, Patil, N.K, Muniyappa, K, Vijayan, M. | | 登録日 | 2014-02-09 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability
J.Biosci., 40, 2015
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