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1YJ9
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Crystal Structure Of The Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui Containing a three residue deletion in L22
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-13
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
1YJN
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BU of 1yjn by Molmil
Crystal Structure Of Clindamycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-14
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
4C4Q
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BU of 4c4q by Molmil
Cryo-EM map of the CSFV IRES in complex with the small ribosomal 40S subunit and DHX29
分子名称: INTERNAL RIBOSOMAL ENTRY SITE
著者Hashem, Y, desGeorges, A, Dhote, V, Langlois, R, Liao, H.Y, Grassucci, R.A, Pestova, T.V, Hellen, C.U.T, Frank, J.
登録日2013-09-07
公開日2013-10-30
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Hepatitis-C-Virus-Like Internal Ribosome Entry Sites Displace Eif3 to Gain Access to the 40S Subunit
Nature, 503, 2013
8B7Y
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BU of 8b7y by Molmil
Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Koller, T.O, Graf, M, Wilson, D.N.
登録日2022-10-03
公開日2023-01-25
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J.Am.Chem.Soc., 145, 2023
6AWB
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BU of 6awb by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state
分子名称: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
著者Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
登録日2017-09-05
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AWD
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BU of 6awd by Molmil
Structure of 30S (S1 depleted) ribosomal subunit and RNA polymerase complex
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
登録日2017-09-05
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
6AWC
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BU of 6awc by Molmil
Structure of 30S ribosomal subunit and RNA polymerase complex in rotated state
分子名称: 16S rRNA, 30S ribosomal protein S1, 30S ribosomal protein S10, ...
著者Demo, G, Rasouly, A, Vasilyev, N, Loveland, A.B, Diaz-Avalos, R, Grigorieff, N, Nudler, E, Korostelev, A.A.
登録日2017-09-05
公開日2017-10-18
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Structure of RNA polymerase bound to ribosomal 30S subunit.
Elife, 6, 2017
8FON
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BU of 8fon by Molmil
Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
登録日2023-01-02
公開日2023-03-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.64 Å)
主引用文献Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
8FOM
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BU of 8fom by Molmil
Crystal structure of tRNA^Lys(SUU) bound to UAA codon in the ribosomal P site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M.
登録日2023-01-02
公開日2023-03-29
最終更新日2023-04-26
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches.
J.Biol.Chem., 299, 2023
6Y69
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BU of 6y69 by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Wieland, M, Wilson, D.N.
登録日2020-02-26
公開日2020-07-01
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
6GSJ
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BU of 6gsj by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAThr in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Yusupov, M, Yusupova, G.
登録日2018-06-14
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Nucleic Acids Res., 46, 2018
6GSL
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BU of 6gsl by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAArg in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Yusupov, M, Yusupova, G.
登録日2018-06-14
公開日2018-07-04
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Nucleic Acids Res., 46, 2018
6GSK
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BU of 6gsk by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNAThr in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Yusupov, M, Yusupova, G.
登録日2018-06-14
公開日2018-07-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.36 Å)
主引用文献Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria.
Nucleic Acids Res., 46, 2018
7PWG
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BU of 7pwg by Molmil
Cryo-EM structure of large subunit of Giardia lamblia ribosome at 2.7 A resolution
分子名称: 60S ribosomal protein L13, 60S ribosomal protein L18a, 60S ribosomal protein L27, ...
著者Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A.
登録日2021-10-06
公開日2022-04-20
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
7PWO
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BU of 7pwo by Molmil
Cryo-EM structure of Giardia lamblia ribosome at 2.75 A resolution
分子名称: 40S ribosomal protein S21, 40S ribosomal protein S26, 40S ribosomal protein S30, ...
著者Hiregange, D.G, Rivalta, A, Bose, T, Breiner-Goldstein, E, Samiya, S, Cimicata, G, Kulakova, L, Zimmerman, E, Bashan, A, Herzberg, O, Yonath, A.
登録日2021-10-07
公開日2022-04-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia.
Nucleic Acids Res., 50, 2022
7OTC
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BU of 7otc by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
著者Wieland, M, Koller, T.O, Wilson, D.N.
登録日2021-06-10
公開日2022-05-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
6GC7
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BU of 6gc7 by Molmil
50S ribosomal subunit assembly intermediate state 1
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
登録日2018-04-17
公開日2018-06-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC6
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BU of 6gc6 by Molmil
50S ribosomal subunit assembly intermediate state 2
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
登録日2018-04-17
公開日2018-07-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6PPF
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BU of 6ppf by Molmil
Bacterial 45SRbgA ribosomal particle class B
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Ortega, J, Seffouh, A, Jain, N, Jahagirdar, D, Basu, K, Razi, A, Ni, X, Guarne, A, Britton, R.A.
登録日2019-07-06
公開日2019-09-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate.
Nucleic Acids Res., 47, 2019
7KLD
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BU of 7kld by Molmil
Crystal Structure of an Essential Ribosomal Processing Protease Prp from S. aureus in complex with a covalently linked product Peptide
分子名称: CALCIUM ION, LYS-LEU-ASN-LEU-GLN-PHE-PCS, Phage-related ribosomal protease
著者Wright, H.T, Peterson, D.
登録日2020-10-29
公開日2021-09-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Phage-Related Ribosomal Protease (Prp) of Staphylococcus aureus : In Vitro Michaelis-Menten Kinetics, Screening for Inhibitors, and Crystal Structure of a Covalent Inhibition Product Complex.
Biochemistry, 61, 2022
6WQQ
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BU of 6wqq by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J.
登録日2020-04-29
公開日2020-06-03
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
6WRU
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BU of 6wru by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J.
登録日2020-04-30
公開日2020-06-03
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
4D67
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BU of 4d67 by Molmil
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
分子名称: 28S RRNA, 5.8S RRNA, 5S RRNA, ...
著者Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T.
登録日2014-11-10
公開日2015-03-04
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State
Mol.Cell, 57, 2015
6WRS
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BU of 6wrs by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J.
登録日2020-04-30
公開日2020-06-03
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020
6WQN
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BU of 6wqn by Molmil
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, contezolid
分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Belousoff, M.J.
登録日2020-04-29
公開日2020-06-03
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Characterization of the Core Ribosomal Binding Region for the Oxazolidone Family of Antibiotics Using Cryo-EM.
Acs Pharmacol Transl Sci, 3, 2020

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