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1SXV
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1.3A Crystal structure of rv3628, Mycobacterium tuberculosis inorganic pyrophosphatase (PPase) at pH5.0
分子名称: GLYCEROL, Inorganic pyrophosphatase, SULFATE ION
著者Benini, S, Wilson, K.S.
登録日2004-03-31
公開日2005-04-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Mycobacterium tuberculosis Rv3628, yet another inorganic pyrophosphatase or a possible drug target?
To be Published
1TFU
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BU of 1tfu by Molmil
phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis
分子名称: Phosphopantetheine adenylyltransferase
著者Morris, V.K, Izard, T, TB Structural Genomics Consortium (TBSGC)
登録日2004-05-27
公開日2004-09-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Substrate-induced asymmetry and channel closure revealed by the apoenzyme structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase.
Protein Sci., 13, 2004
1ZVW
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BU of 1zvw by Molmil
The Crystal Structure of TrpD (Rv2192c) from Mycobacterium tuberculosis in Complex with PRPP and Magnesium
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, BENZAMIDINE, ...
著者Lee, C.E, Lott, J.S, Baker, E.N, Arcus, V.L, Javid-Majd, F, Goodfellow, C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC)
登録日2005-06-02
公開日2006-01-17
最終更新日2021-08-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate.
J.Mol.Biol., 355, 2006
3FVE
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BU of 3fve by Molmil
Crystal structure of diaminopimelate epimerase Mycobacterium tuberculosis DapF
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Diaminopimelate epimerase, GLYCEROL
著者Usha, V, Dover, L.G, Roper, D.I, Futterer, K, Besra, G.S.
登録日2009-01-15
公開日2009-01-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the diaminopimelate epimerase DapF from Mycobacterium tuberculosis
Acta Crystallogr.,Sect.D, 65, 2009
1YL7
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BU of 1yl7 by Molmil
the crystal structure of Mycobacterium tuberculosis dihydrodipicolinate reductase (Rv2773c) in complex with NADH (crystal form C)
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Dihydrodipicolinate reductase, MAGNESIUM ION
著者Janowski, R, Kefala, G, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2005-01-19
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The structure of dihydrodipicolinate reductase (DapB) from Mycobacterium tuberculosis in three crystal forms.
Acta Crystallogr.,Sect.D, 66, 2010
8T5N
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BU of 8t5n by Molmil
Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound)
分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-06-14
公開日2023-06-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of Glycine--tRNA ligase from Mycobacterium tuberculosis (AMP-Mg bound)
To be published
1Z8F
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Guanylate Kinase Double Mutant A58C, T157C from Mycobacterium tuberculosis (Rv1389)
分子名称: FORMIC ACID, Guanylate kinase
著者Chan, S, Sawaya, M.R, Choi, B, Zocchi, G, Perry, L.J, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-03-30
公開日2005-04-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Guanylate Kinase from Mycobacterium tuberculosis (Rv1389)
To be Published
5EBC
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Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P21 (state III)
分子名称: CALCIUM ION, ESX-1 secretion system protein eccB1
著者Zhang, X.L, Qi, C, Xie, X.Q, Li, D.F, Bi, L.J.
登録日2015-10-19
公開日2016-02-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic observation of the movement of the membrane-distal domain of the T7SS core component EccB1 from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 72, 2016
4GZR
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BU of 4gzr by Molmil
Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221
分子名称: ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION
著者Arbing, M.A, Chan, S, He, Q, Harris, L, Zhou, T.T, Kuo, E, Ahn, C.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
登録日2012-09-06
公開日2012-09-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
3FHZ
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Crystal structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and co-repressor, L-arginine
分子名称: 5'-D(*TP*GP*TP*TP*GP*CP*AP*TP*AP*AP*CP*GP*AP*TP*GP*CP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*CP*AP*TP*CP*GP*TP*TP*AP*TP*GP*CP*AP*AP*CP*A)-3', ACETATE ION, ...
著者Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2008-12-10
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine.
J.Mol.Biol., 388, 2009
2UYO
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Crystal structure of ML2640c from Mycobacterium leprae in an hexagonal crystal form
分子名称: HYPOTHETICAL PROTEIN ML2640
著者Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Miras, I, Shepard, W, Alzari, P.M.
登録日2007-04-11
公開日2007-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria.
Protein Sci., 16, 2007
7BZ6
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BU of 7bz6 by Molmil
Mycobacterium bovis AhpC
分子名称: Alkyl hydroperoxide reductase C peptide
著者Chong, S.M.S, Neelagandan, K, Gruber, G.
登録日2020-04-27
公開日2021-03-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.302 Å)
主引用文献Residues of helix alpha2 are critical for catalytic efficiency of mycobacterial alkylhydroperoxide reductase subunit C.
Febs Lett., 594, 2020
3GXO
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BU of 3gxo by Molmil
Structure of the Mitomycin 7-O-methyltransferase MmcR with bound Mitomycin A
分子名称: CALCIUM ION, MmcR, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Singh, S, Chang, A, Bingman, C.A, Phillips Jr, G.N, Thorson, J.S.
登録日2009-04-02
公開日2010-04-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural characterization of the mitomycin 7-O-methyltransferase.
Proteins, 79, 2011
3HSS
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BU of 3hss by Molmil
A higher resolution structure of Rv0554 from Mycobacterium tuberculosis complexed with malonic acid
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ...
著者Johnston, J.M, Baker, E.N.
登録日2009-06-10
公開日2010-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional analysis of Rv0554 from Mycobacterium tuberculosis: testing a putative role in menaquinone biosynthesis.
Acta Crystallogr.,Sect.D, 66, 2010
2Q74
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Mycobacterium tuberculosis SuhB
分子名称: Inositol-1-monophosphatase
著者Brown, A.K, Meng, G, Ghadbane, H, Besra, G.S, Futterer, K.
登録日2007-06-06
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg2+
Bmc Struct.Biol., 7, 2007
1XXX
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Crystal structure of Dihydrodipicolinate Synthase (DapA, Rv2753c) from Mycobacterium tuberculosis
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Dihydrodipicolinate synthase, ...
著者Kefala, G, Panjikar, S, Janowski, R, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2004-11-09
公開日2006-02-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.
Biochem.J., 411, 2008
1W66
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Structure of a lipoate-protein ligase b from Mycobacterium tuberculosis
分子名称: DECANOIC ACID, LIPOYLTRANSFERASE
著者Ma, Q, Wilmanns, M.
登録日2004-08-13
公開日2005-12-08
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献The Mycobacterium Tuberculosis Lipb Enzyme Functions as a Cysteine/Lysine Dyad Acyltransferase.
Proc.Natl.Acad.Sci.USA, 103, 2006
2UYQ
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Crystal structure of ML2640c from Mycobacterium leprae in complex with S-adenosylmethionine
分子名称: HYPOTHETICAL PROTEIN ML2640, S-ADENOSYLMETHIONINE
著者Grana, M, Buschiazzo, A, Wehenkel, A, Haouz, A, Miras, I, Shepard, W, Alzari, P.M.
登録日2007-04-11
公開日2007-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of M. Leprae Ml2640C Defines a Large Family of Putative S-Adenosylmethionine- Dependent Methyltransferases in Mycobacteria.
Protein Sci., 16, 2007
2LCA
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BU of 2lca by Molmil
Solution structure of the C domain of RV0899 from mycobacterium tuberculosis
分子名称: Uncharacterized protein Rv0899/MT0922
著者Marassi, F, Yao, Y.
登録日2011-04-26
公開日2012-01-04
最終更新日2023-12-06
実験手法SOLUTION NMR
主引用文献Molecular Structure and Peptidoglycan Recognition of Mycobacterium tuberculosis ArfA (Rv0899).
J.Mol.Biol., 416, 2012
4KG7
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Structure of MycP3 protease from the type VII (ESX-3) secretion system.
分子名称: CHLORIDE ION, Peptidase S8 and S53, subtilisin, ...
著者Korotkov, K.V, Evans, T.J.
登録日2013-04-28
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
J.Struct.Biol., 184, 2013
2QLP
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Bifunctional dCTP deaminase:dUTPase from Mycobacterium tuberculosis, apo form
分子名称: Deoxycytidine triphosphate deaminase, PENTAETHYLENE GLYCOL
著者Christophersen, S, Harris, P, Willemoes, M.
登録日2007-07-13
公開日2008-02-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Mechanism of dTTP inhibition of the bifunctional dCTP deaminase:dUTPase encoded by Mycobacterium tuberculosis
J.Mol.Biol., 376, 2007
2GES
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BU of 2ges by Molmil
Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-I (RT)
分子名称: Pantothenate kinase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-4-{[3-({2-[(2-HYDROXYETHYL)DITHIO]ETHYL}AMINO)-3-OXOPROPYL]AMINO}-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M.
登録日2006-03-20
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.
Acta Crystallogr.,Sect.D, 62, 2006
2LBT
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Solution structure of the C domain of RV0899(D236A) from mycobacterium tuberculosis
分子名称: Uncharacterized protein Rv0899/MT0922
著者Yao, Y, Marassi, F.
登録日2011-04-06
公開日2012-01-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Molecular Structure and Peptidoglycan Recognition of Mycobacterium tuberculosis ArfA (Rv0899).
J.Mol.Biol., 416, 2012
2GET
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Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-I (LT)
分子名称: GLYCEROL, Pantothenate kinase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-4-{[3-({2-[(2-HYDROXYETHYL)DITHIO]ETHYL}AMINO)-3-OXOPROPYL]AMINO}-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE
著者Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M.
登録日2006-03-20
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.
Acta Crystallogr.,Sect.D, 62, 2006
2GEV
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Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-II (LT)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Pantothenate kinase, ...
著者Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M.
登録日2006-03-20
公開日2006-06-06
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.
Acta Crystallogr.,Sect.D, 62, 2006

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